Single versus staged epidural injections of 0.75% bupivacaine: pharmacokinetic and pharmacodynamic effects.

abstract：BACKGROUND:Current guidelines from the American College of Obstetricians and Gynecologists recommend antibiotic prophylaxis for cesarean delivery immediately before incision. The purpose of this study was to measure and describe correlates of adherence to these guidelines in a sample of United States anesthesiologists....

journal_title：Anesthesia and analgesia

authors： Raghunathan K,Connelly NR,Friderici J,Naglieri-Prescod D,Joyce R,Prasanna P,Ponnusamy N

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The increasing demand for anesthetic procedures in the gastrointestinal endoscopy area has not been followed by a similar increase in the methods to provide and control sedation and analgesia for these patients. In this study, we evaluated different combinations of propofol and remifentanil, administered thr...

journal_title：Anesthesia and analgesia

authors： Gambús PL,Jensen EW,Jospin M,Borrat X,Martínez Pallí G,Fernández-Candil J,Valencia JF,Barba X,Caminal P,Trocóniz IF

更新日期：2011-02-01 00:00:00

abstract：UNLABELLED:Diabetic patients are at increased risk of wound infection after major surgery, but the effect of perioperative glucose control on postoperative wound infection rates after surgery is uncertain. We tested the effect of an insulin infusion on perioperative neutrophil function in diabetic patients scheduled fo...

journal_title：Anesthesia and analgesia

authors： Rassias AJ,Marrin CA,Arruda J,Whalen PK,Beach M,Yeager MP

更新日期：1999-05-01 00:00:00

abstract：:The effects of anesthetics on intracranial pressure (ICP) may be different in preterm neonates than in adults because the neonate's cranial sutures are not yet fused. The authors monitored changes in anterior fontanel pressure (AFP), a noninvasive indicator of ICP, during anesthesia in 44 preterm neonates without neur...

journal_title：Anesthesia and analgesia

authors： Friesen RH,Thieme RE,Honda AT,Morrison JE Jr

更新日期：1987-05-01 00:00:00

abstract：UNLABELLED:Children undergoing placement of bilateral myringotomy tubes (BMT) often exhibit pain-related behavior (agitation) in the postanesthesia care unit. We compared the emergence and recovery profiles of pediatric patients who received sevoflurane with or without supplementary intranasal fentanyl for BMT surgery....

journal_title：Anesthesia and analgesia

authors： Finkel JC,Cohen IT,Hannallah RS,Patel KM,Kim MS,Hummer KA,Choi SS,Pena M,Schreiber SB,Zalzal G

更新日期：2001-05-01 00:00:00

abstract：UNLABELLED:The transient hyperemic response (THR) test has been used to assess cerebral autoregulation in anesthesia and intensive care. To date it has not been compared with the static autoregulation test for assessing graded changes in cerebral autoregulation. We compared the two tests during propofol, desflurane, an...

journal_title：Anesthesia and analgesia

authors： Tibble RK,Girling KJ,Mahajan RP

更新日期：2001-07-01 00:00:00

abstract：UNLABELLED:One thousand questionnaires concerning the techniques and complications of intravenous regional anesthesia (IVRA) were sent to 900 American and 100 Canadian anesthesiologists. Of the 321 respondents, 86% perform IVRA regularly. A wide variation in device-related and clinical aspects was found, ranging from a...

journal_title：Anesthesia and analgesia

authors： Henderson CL,Warriner CB,McEwen JA,Merrick PM

更新日期：1997-10-01 00:00:00

abstract：:Nicardipine is used in the treatment of premature labor. There are no previous reports in the anesthesia literature of serious side effects associated with this drug. We report a case of pulmonary edema induced by nicardipine therapy for tocolysis in a pregnant 27-yr-old patient admitted to our hospital for preterm la...

journal_title：Anesthesia and analgesia

authors： Bal L,Thierry S,Brocas E,Adam M,Van de Louw A,Tenaillon A

更新日期：2004-09-01 00:00:00

abstract：:We used laser-Doppler flowmetry to compare the effects of the volatile anesthetics, isoflurane and halothane, on the cerebrovascular response to CO2 inhalation in male Sprague-Dawley rats. The effects of 0.5 and 1.5 minimum alveolar anesthetic concentrations (MAC) of halothane and isoflurane on the microcirculatory re...

journal_title：Anesthesia and analgesia

authors： Lee JG,Smith JJ,Hudetz AG,Hillard CJ,Bosnjak ZJ,Kampine JP

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Nerve-stimulated fade in muscle is generally accepted as a prejunctional phenomenon mediated by block of prejunctional acetylcholine receptors (AChRs) at the nerve terminal, whereas decrease of twitch tension is considered a postjunctional effect due to block of muscle AChRs. Using ligands with specific pre-...

journal_title：Anesthesia and analgesia

authors： Nagashima M,Yasuhara S,Martyn JA

更新日期：2013-05-01 00:00:00

abstract：:The pharmacokinetics of sufentanil were studied in 28 pediatric patients undergoing cardiovascular procedures. Patients were divided into four groups on the basis of age: neonates (0-1 month, n = 9), infants (1-24 months, n = 7), children (2-12 yr, n = 7), and adolescents (12-18 yr, n = 5). Sufentanil 10-15 micrograms...

journal_title：Anesthesia and analgesia

authors： Greeley WJ,de Bruijn NP,Davis DP

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Although the mechanical status of the lungs affects the shape of the capnogram, the relations between the capnographic parameters and those reflecting the airway and lung tissue mechanics have not been established in mechanically ventilated patients. We, therefore, set out to characterize how the mechanical ...

journal_title：Anesthesia and analgesia

authors： Csorba Z,Petak F,Nevery K,Tolnai J,Balogh AL,Rarosi F,Fodor GH,Babik B

更新日期：2016-05-01 00:00:00

abstract：:We studied the effect of halothane on the fetal cardiovascular system of six lambs in utero by measuring fetal heart rate and femoral arterial blood pressure and by injecting labeled microspheres during a control period and again after 60 and 90 min of halothane anesthesia administered to six pregnant ewes at an inspi...

journal_title：Anesthesia and analgesia

authors： Biehl DR,Tweed WA,Cote J,Wade JG,Sitar D

更新日期：1983-05-01 00:00:00

abstract：UNLABELLED:Because anesthetic technique has the potential to dramatically affect cerebral blood flow and metabolism (two determinants of brain thermoregulation), we tested the hypothesis that, after craniotomy, anesthetic technique would influence brain temperature independent of core temperature. Twenty-one cats (2.7 ...

journal_title：Anesthesia and analgesia

authors： Erickson KM,Lanier WL

更新日期：2003-05-01 00:00:00

abstract：:This study used the activated clotting time (ACT) to determine the clinical onset of four different doses of heparin after bolus injection into the central circulation. Ten consenting adults (Group A) undergoing coronary artery bypass grafting were given 350 U/kg of bovine lung heparin and had simultaneous duplicate a...

journal_title：Anesthesia and analgesia

authors： Heres EK,Speight K,Benckart D,Marquez J,Gravlee GP

更新日期：2001-06-01 00:00:00

abstract：:We have determined that the mixed agonist-antagonist narcotic, butorphanol, improves CO2 response and ventilation after fentanyl anesthesia. A tentative dosage range has been established. Twenty-two patients were anesthetized with isoflurane, nitrous oxide, and fentanyl, which was continuously infused throughout the s...

journal_title：Anesthesia and analgesia

authors： Bowdle TA,Greichen SL,Bjurstrom RL,Schoene RB

更新日期：1987-06-01 00:00:00

abstract：UNLABELLED:Nitric oxide (NO) may play an important role in central and peripheral nociceptive processes. However, its contribution to peripheral antinociception is still not clear. In the present study, we investigated the effect of peripherally administered FK409, a spontaneous NO releaser, and its interaction with pe...

journal_title：Anesthesia and analgesia

authors： Nozaki-Taguchi N,Yamamoto T

更新日期：1998-02-01 00:00:00

abstract：:Sufentanil is a potent opioid that occasionally has been associated with hypotension. The mechanism behind this hypotension is unclear. We hypothesized that sufentanil had a direct effect on vascular smooth muscle to cause vasodilation. Sufentanil was infused into the brachial artery of 10 young, healthy volunteers at...

journal_title：Anesthesia and analgesia

authors： Ebert TJ,Ficke DJ,Arain SR,Holtz MN,Shankar H

更新日期：2005-12-01 00:00:00

abstract：:In recent years, there have been escalating concerns related to the opioid epidemic. With a steadily increasing opioid supply, it is critical to provide proper education to patients who are prescribed these medications. Education should be emphasized as a means of ensuring safe use and potentially as a strategy for cu...

journal_title：Anesthesia and analgesia

authors： Lee BH,Wu CL

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Premedication with midazolam is commonly used in children to reduce anxiety and improve cooperation before anesthesia. However, it has the potential to alter respiratory function because of its muscle relaxant properties. We assessed functional residual capacity (FRC), ventilation homogeneity, using a lung c...

journal_title：Anesthesia and analgesia

authors： von Ungern-Sternberg BS,Erb TO,Habre W,Sly PD,Hantos Z

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Currently, the monitoring of cardiac output (CO) and stroke volume (SV) is mainly performed using invasive techniques. Therefore, performing CO monitoring noninvasively by means of electrical impedance tomography (EIT) would be advantageous for intensive care. Our hypothesis was that, by means of EIT, it is ...

journal_title：Anesthesia and analgesia

authors： Pikkemaat R,Lundin S,Stenqvist O,Hilgers RD,Leonhardt S

更新日期：2014-07-01 00:00:00

abstract：:Morphine given intracerebroventricularly releases spinal dynorphin A (Dyn) in mice. The present study was undertaken to determine whether morphine given intrathecally (IT) released Dyn. We demonstrated that the antinociceptive action of morphine was enhanced by procedures that are known to attenuate Dyn action. First,...

journal_title：Anesthesia and analgesia

authors： Holmes BB,Fujimoto JM

更新日期：1993-12-01 00:00:00

abstract：:The purpose of this canine study was to examine the cerebral vascular and metabolic effects of adding nitrous oxide to isoflurane from 1.4% expired (1 MAC) up to a concentration giving an isoelectric electroencephalogram (EEG). Cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) were determined us...

journal_title：Anesthesia and analgesia

authors： Roald OK,Forsman M,Heier MS,Steen PA

更新日期：1991-01-01 00:00:00

abstract：UNLABELLED:Previous studies of samples from cranial meninges have created doubts about the existence of a virtual subdural space. We examined the ultrastructure of spinal meninges from three human cadavers immediately after death to see whether there is a virtual subdural space at this level. The arachnoid mater had tw...

journal_title：Anesthesia and analgesia

authors： Reina MA,De Leon Casasola O,López A,De Andrés JA,Mora M,Fernández A

更新日期：2002-04-01 00:00:00

abstract：:Activity of methionine synthetase was measured in liver biopsies of seven patients who had received 50% to 70% nitrous oxide supplemented by a combination of a narcotic and/or barbiturate with or without a volatile anesthetic, and from seven patients who were anesthetized without nitrous oxide (control group). Methion...

journal_title：Anesthesia and analgesia

authors： Koblin DD,Waskell L,Watson JE,Stokstad EL,Eger EI 2nd

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:Growing awareness of the negative impacts from the practice of health care on the environment and public health calls for the routine inclusion of life cycle criteria into the decision-making process of device selection. Here we present a life cycle assessment of 2 laryngeal mask airways (LMAs), a one-time-u...

journal_title：Anesthesia and analgesia

authors： Eckelman M,Mosher M,Gonzalez A,Sherman J

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Lidocaine can alleviate acute as well as chronic neuropathic pain at very low plasma concentrations in humans and laboratory animals. The mechanism(s) underlying lidocaine's analgesic effect when administered systemically is poorly understood but clearly not related to interruption of peripheral nerve conduc...

journal_title：Anesthesia and analgesia

authors： Luo Z,Yu M,Smith SD,Kritzer M,Du C,Ma Y,Volkow ND,Glass PS,Benveniste H

更新日期：2009-01-01 00:00:00

abstract：UNLABELLED:We investigated the impact of cardiopulmonary bypass pump (CPB), hematocrit, gender, age, and body weight on blood use in patients undergoing coronary artery bypass graft surgery at a major university hospital. Participants were 1235 consecutive patients undergoing primary coronary artery surgery over a peri...

journal_title：Anesthesia and analgesia

authors： Scott BH,Seifert FC,Glass PS,Grimson R

更新日期：2003-10-01 00:00:00

abstract：:Increasing reports of latex-induced anaphylaxis make preoperative identification of latex-sensitive individuals an important concern. The incidence of latex sensitivity and the efficacy of questionnaires in identifying this in ambulatory surgical populations have not been determined. To clarify these issues, 996 ambul...

journal_title：Anesthesia and analgesia

authors： Lebenbom-Mansour MH,Oesterle JR,Ownby DR,Jennett MK,Post SK,Zaglaniczy K

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Helium produces preconditioning against myocardial infarction by activating prosurvival signaling, but whether nitric oxide (NO) generated by endothelial NO synthase plays a role in this phenomenon is unknown. We tested the hypothesis that NO mediates helium-induced cardioprotection in vivo. METHODS:Rabbits...

journal_title：Anesthesia and analgesia

authors： Pagel PS,Krolikowski JG,Pratt PF Jr,Shim YH,Amour J,Warltier DC,Weihrauch D

更新日期：2008-09-01 00:00:00