Insulin infusion improves neutrophil function in diabetic cardiac surgery patients.

abstract：:The mechanisms of succinylcholine-induced cardiac effects have not been fully elucidated. Accordingly, we studied the effects of succinylcholine on atrial rate and contractile force in the isolated canine atrium perfused with donor blood. The sinus node artery was perfused with heparinized blood from the common caroti...

journal_title：Anesthesia and analgesia

authors： Saegusa K,Furukawa Y,Takeda M,Chiba S

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Synergistic neuromuscular blocking effects have been observed clinically with certain pairs of nicotinic acetylcholine receptor (nAChR) competitive antagonists. The mechanism for synergy has not been elucidated. We tested the hypothesis that synergy arises from a differential selectivity of antagonists for t...

journal_title：Anesthesia and analgesia

authors： Liu M,Dilger JP

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Recently, there has been significant focus on the effects of anesthesia on the developing brain. Concern is heightened in children <3 years of age requiring lengthy and/or multiple anesthetics. Hypospadias correction is common in otherwise healthy children and may require both lengthy and repeated anesthetic...

journal_title：Anesthesia and analgesia

authors： Adler AC,Chandrakantan A,Sawires Y,Lee AD,Hart M,Koh CJ,Janzen NK,Austin PF,Andropoulos DB

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:Obesity causes multiorgan dysfunction, specifically metabolic abnormalities in the liver. Obese patients are opioid-sensitive and have high rates of respiratory complications after surgery. Obesity also has been shown to cause resistance to leptin, an adipose-derived hormone that is key in regulating hunger,...

journal_title：Anesthesia and analgesia

authors： Dalesio NM,Hendrix CW,McMichael DH,Thompson CB,Lee CK,Pho H,Arias RS,Lynn RR,Galinkin J,Yaster M,Brown RH,Schwartz AR

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Although our understanding of nociceptive processing during anesthesia has increased greatly over the last decade, many patients still experience hyperalgesia and acute pain postoperatively. The noxious-induced withdrawal reflex (NIWR) model is specifically designed and validated to quantitatively study the ...

journal_title：Anesthesia and analgesia

authors： Sommers MG,Nguyen NK,Veening JG,Vissers KC,Ritskes-Hoitinga M,van Egmond J

更新日期：2008-04-01 00:00:00

abstract：:To learn the latest developments in the various forms of postoperative cognitive dysfunction, a group of scientists and physicians met in Stockholm for a full day of presentations and interactive discussions. This article summarizes the discussion; highlighting progress, challenges, and new directions in the area of p...

journal_title：Anesthesia and analgesia

authors： Terrando N,Eriksson LI,Eckenhoff RG

更新日期：2015-03-01 00:00:00

abstract：:Initial, but not subsequent, inhalation of 8% desflurane produces transient sympathetic stimulation. We hypothesized that initial but not subsequent increases should produce pupil dilation, and that N2O, fentanyl, and clonidine, but not esmolol, should blunt the response. In 10 volunteers, we maintained anesthesia wit...

journal_title：Anesthesia and analgesia

authors： Daniel M,Larson MD,Eger EI 2nd,Noorani M,Weiskopf RB

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:We have recently shown that levetiracetam, administered systemically, exerts an antihyperalgesic effect in a rat inflammatory pain model. In this study, we examined whether levetiracetam has local peripheral antihyperalgesic/anti-edematous effects in the same model of localized inflammation and whether opioi...

journal_title：Anesthesia and analgesia

authors： Stepanović-Petrović RM,Micov AM,Tomić MA,Ugrešić ND

更新日期：2012-12-01 00:00:00

abstract：:Critically ill patients often have cardiopulmonary perturbations that require rapid and frequent assessment for optimal care, including cardiac output determinations, measurement of cardiac filling pressures, and arterial and mixed venous blood gas determinations. We evaluated the performance of a rapid, on-demand bed...

journal_title：Anesthesia and analgesia

authors： Franklin ML,Peruzzi WT,Moen SG,Shapiro BA

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:There is a pronounced learning curve for the technique of ultrasound-guided regional anesthesia. Practicing with a simulator model has been shown to speed the acquisition of these skills for various ultrasound-guided procedures. However, commercial models for ultrasound-guided regional anesthesia may be too ...

journal_title：Anesthesia and analgesia

authors： Liu Y,Glass NL,Power RW

更新日期：2010-04-01 00:00:00

abstract：:To determine whether concentrations of diethylaminoethanol (DEAE) and procaine below those that reduce the amplitude of action potentials might alter the excitability of brain cells, a single microelectrode intracellular recording technique was used to measure firing threshold and action potential amplitude of pyramid...

journal_title：Anesthesia and analgesia

authors： Butterworth JF 4th,Cole LR

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Animal models show us that specific activation of the p38 mitogen-activated protein kinase (MAPK) may be a pivotal step in lidocaine neurotoxicity, but this has not been investigated in the case of two very widely used local anesthetics, bupivacaine and ropivacaine. We investigated the hypotheses that these ...

journal_title：Anesthesia and analgesia

authors： Lirk P,Haller I,Colvin HP,Lang L,Tomaselli B,Klimaschewski L,Gerner P

更新日期：2008-05-01 00:00:00

abstract：:Epinephrine-induced dysrhythmias were studied in 19 dogs anesthetized with 1.25 MAC enflurane or isoflurane, or the same preceded by thiopental (20 mg/kg). In 11 (group 1) dogs, thiopental reduced the dose of epinephrine required for production of ventricular ectopy, bigeminy and tachycardia with enflurane, and only v...

journal_title：Anesthesia and analgesia

authors： Atlee JL 3rd,Roberts FL

更新日期：1986-05-01 00:00:00

abstract：:The anesthetic propofol (2,6 diisopropylphenol) mediates some of its effects by activating inhibitory chloride currents in the lower brainstem and spinal cord. The effects comprise direct activation of gamma-aminobutyric acid-A and glycine receptors in the absence of the natural agonist, as well as potentiation of the...

journal_title：Anesthesia and analgesia

authors： Ahrens J,Haeseler G,Leuwer M,Mohammadi B,Krampfl K,Dengler R,Bufler J

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Patients with lung failure who undergo prone positioning often receive extended hemodynamic monitoring. We investigated the influence of modified prone positioning (135°) on the accuracy of pulse contour-derived calibrated cardiac index (CIPC) and uncalibrated cardiac index (CIVIG) in this patient population...

journal_title：Anesthesia and analgesia

authors： Grensemann J,Bruecken U,Treszl A,Wappler F,Sakka SG

更新日期：2013-04-01 00:00:00

abstract：:Sufentanil is a potent opioid that occasionally has been associated with hypotension. The mechanism behind this hypotension is unclear. We hypothesized that sufentanil had a direct effect on vascular smooth muscle to cause vasodilation. Sufentanil was infused into the brachial artery of 10 young, healthy volunteers at...

journal_title：Anesthesia and analgesia

authors： Ebert TJ,Ficke DJ,Arain SR,Holtz MN,Shankar H

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Skeletal muscle failure in critical illness (intensive care unit-acquired weakness) is a well-known complication developing early during intensive care unit stay. However, muscle weakness during the perioperative setting has not yet been investigated. METHODS:We performed a subgroup investigation of a prosp...

journal_title：Anesthesia and analgesia

authors： Lachmann G,Mörgeli R,Kuenz S,Piper SK,Spies C,Kurpanik M,Weber-Carstens S,Wollersheim T,BIOCOG Consortium.

更新日期：2020-02-01 00:00:00

abstract：UNLABELLED:N-methyl-D-aspartate (NMDA) antagonists, such as MK801, delay the development of morphine tolerance. Magnesium, a noncompetitive NMDA antagonist, reduces postoperative morphine requirements. The present study was designed to evaluate the effects of intrathecal co-administration of magnesium sulfate with morp...

journal_title：Anesthesia and analgesia

authors： McCarthy RJ,Kroin JS,Tuman KJ,Penn RD,Ivankovich AD

更新日期：1998-04-01 00:00:00

abstract：:As part of an oximetry research effort in which plethysmographic data were collected from moving patients, a wide variety of patient motion affecting pulse oximetry was observed and characterized by the clinical incidence, type, severity and duration of patient motion. 350 patients were observed for movement in clinic...

journal_title：Anesthesia and analgesia

authors： Tobin RM,Pologe JA,Batchelder PB

更新日期：2002-01-01 00:00:00

abstract：UNLABELLED:Surgery causes changes in hemostasis, leading to a hypercoagulable state that has been linked to both arterial and venous thrombotic complications. The etiology of this state is unknown, but many investigators have hypothesized that perioperative neuroendocrine changes are responsible. We have previously dem...

journal_title：Anesthesia and analgesia

authors： Rosenfeld BA,Nguyen ND,Sung I,Faraday N

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Insufficient fixation of an epidural catheter may result in migration of the catheter and eventual catheter failure. However, the best fixation method remains to be established. Aron Alpha A (2-ethyl cyanoacrylate) adhesive is approved for clinical use and can be used for surgical adhesion to both skin and b...

journal_title：Anesthesia and analgesia

authors： Tadokoro T,Kakinohana M,Navarro M,Goya M,Odo Y

更新日期：2019-07-01 00:00:00

abstract：UNLABELLED:In the present study, we investigated the effect of remifentanil on cerebral blood flow velocity (CBFV). We investigated 20 patients (ASA physical status III) scheduled for elective coronary artery bypass graft surgery. Anesthesia was induced with remifentanil 5 microg/kg IV (Group 1, n = 10) or 2 microg/kg ...

journal_title：Anesthesia and analgesia

authors： Paris A,Scholz J,von Knobelsdorff G,Tonner PH,Schulte am Esch J

更新日期：1998-09-01 00:00:00

abstract：INTRODUCTION:Serious complications are common during the intensive care of postoperative cardiac surgery patients. Some of these complications may be influenced by communication during the process of handover of care from the operating room to the intensive care unit (ICU) team. A structured transfer of care process ma...

journal_title：Anesthesia and analgesia

authors： Hall M,Robertson J,Merkel M,Aziz M,Hutchens M

更新日期：2017-08-01 00:00:00

abstract：UNLABELLED:We assessed the role of vasopressin (VP) for the hemodynamic response to pneumoperitoneum in pigs. Four groups of anesthetized pigs were investigated. Nine pigs were intraabdominally insufflated with CO2 and eight were intraabdominally insufflated with argon; eight pigs received an i.v. injection of 1 mg/kg ...

journal_title：Anesthesia and analgesia

authors： Mann C,Boccara G,Pouzeratte Y,Eliet J,Serradel-Le Gal C,Vergnes C,Bichet DG,Guillon G,Fabre JM,Colson P

更新日期：1999-08-01 00:00:00

abstract：UNLABELLED:We determined the effects of fentanyl, sufentanil, morphine, and meperidine on the spontaneous contractility of isolated human pregnant uterine muscle strips. Uterine specimens were obtained from normal full-term parturients undergoing elective lower-segment cesarean delivery. Longitudinal muscle strips were...

journal_title：Anesthesia and analgesia

authors： Yoo KY,Lee J,Kim HS,Jeong SW

更新日期：2001-04-01 00:00:00

abstract：:We investigated the anesthetic and analgesic effectiveness of adding dexamethasone to lidocaine for IV regional anesthesia (IVRA). Seventy-five patients undergoing ambulatory hand surgery were randomly assigned to one of three groups: group L received 3 mg/kg lidocaine, group LD received 3 mg/kg lidocaine + 8 mg dexam...

journal_title：Anesthesia and analgesia

authors： Bigat Z,Boztug N,Hadimioglu N,Cete N,Coskunfirat N,Ertok E

更新日期：2006-02-01 00:00:00

abstract：UNLABELLED:Endothelial dysfunction and platelet activation with thromboxane release may contribute to spasm or alterations in internal mammary artery (IMA) graft flow during coronary artery surgery. Clevidipine, an ultrashort-acting dihydropyridine calcium channel blocker, is undergoing clinical development, but there ...

journal_title：Anesthesia and analgesia

authors： Huraux C,Makita T,Szlam F,Nordlander M,Levy JH

更新日期：1997-11-01 00:00:00

abstract：:Spine surgery is associated with a wide range of surgical and anesthetic complications. Excessive cerebrospinal fluid leak can be a cause of cerebellar hemorrhage postoperatively. We report a 43-yr-old patient who had lumbar spine reexploration surgery complicated by a cerebrospinal fluid leak which led to cerebellar ...

journal_title：Anesthesia and analgesia

authors： Farag E,Abdou A,Riad I,Borsellino SR,Schubert A

更新日期：2005-02-01 00:00:00

abstract：:Primary sensory nerves transmit information to both the periphery and central nervous systems, and they mediate neurogenic inflammation by release of neurotransmitters, such as tachykinins, in the periphery. Because the effect of local anesthetics on neurogenic inflammation is a subject of controversy, we investigated...

journal_title：Anesthesia and analgesia

authors： Takakura K,Mizogami M,Morishima S,Muramatsu I

更新日期：2006-09-01 00:00:00

abstract：UNLABELLED:Small-dose ketamine in combination with sedative drugs has increasingly been used for sedation and analgesia in local anesthesia. We compared the clinical efficacy of midazolam with two different ketamine infusion regimens during plastic surgery under local anesthesia. Sixty patients undergoing plastic surge...

journal_title：Anesthesia and analgesia

authors： Deng XM,Xiao WJ,Luo MP,Tang GZ,Xu KL

更新日期：2001-11-01 00:00:00