Low concentrations of procaine and diethylaminoethanol reduce the excitability but not the action potential amplitude of hippocampal pyramidal cells.

abstract：BACKGROUND:Capsaicin, the active component of chili peppers, can produce sensory-selective peripheral nerve blockade. Coadministration of capsaicin and tetrodotoxin, a site-1 sodium channel blocker, can achieve a synergistic effect on duration of nerve blocks. However, capsaicin can be neurotoxic, and tetrodotoxin can ...

journal_title：Anesthesia and analgesia

authors： Shomorony A,Santamaria CM,Zhao C,Rwei AY,Mehta M,Zurakowski D,Kohane DS

更新日期：2019-09-01 00:00:00

abstract：:A quest for a systems-level neuroscientific basis of anesthetic-induced loss and return of consciousness has been in the forefront of research for the past 2 decades. Recent advances toward the discovery of underlying mechanisms have been achieved using experimental electrophysiology, multichannel electroencephalograp...

journal_title：Anesthesia and analgesia

authors： Hudetz AG,Mashour GA

更新日期：2016-11-01 00:00:00

abstract：UNLABELLED:Besides having important hormonal effects, progesterone has depressant and hypnotic effects on the brain. In this study, we compared women in the follicular phase with low progesterone levels and in the luteal phase with high progesterone levels regarding their anesthetic requirements. Twenty patients with m...

journal_title：Anesthesia and analgesia

authors： Erden V,Yangin Z,Erkalp K,Delatioğlu H,Bahçeci F,Seyhan A

更新日期：2005-10-01 00:00:00

abstract：:The purpose of the present study was to quantify the inhibitory effect of inhaled halothane and isoflurane on acute hypercapnia-induced responses of capacitance-regulating veins and related cardiovascular variables in response to sequential 40-s periods of 5%, 10%, 15%, and 20% inspired CO2 (FICO2). Measurements were ...

journal_title：Anesthesia and analgesia

authors： Stekiel TA,Stekiel WJ,Tominaga M,Stadnicka A,Bosnjak ZJ,Kampine JP

更新日期：1996-02-01 00:00:00

abstract：:The importance of timely administration of antibiotics for prophylaxis of surgical site infections has led to pressure on anesthesiologists to administer antibiotics. We present a survey of members of the American Association of Clinical Directors designed to evaluate the role of the anesthesiologist in the selection ...

journal_title：Anesthesia and analgesia

authors： Warters RD,Szmuk P,Pivalizza EG,Gebhard RE,Katz J,Ezri T,American Association of Clinical Directors.

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Perioperative respiratory adverse events (PRAEs) account for the major cause of morbidity and mortality in children undergoing general anesthesia. In our institutional clinical practice, we suspected that African American children experienced untoward respiratory events more frequently than other racial grou...

journal_title：Anesthesia and analgesia

authors： Tariq S,Syed M,Martin T,Zhang X,Schmitz M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:IV infusion systems can be configured with manifolds connecting multiple drug infusion lines to transcutaneous catheters. Prior in vitro studies suggest that there may be significant lag times for drug delivery to reflect changes in infusion rates set at the pump, especially with low drug and carrier flows a...

journal_title：Anesthesia and analgesia

authors： Lovich MA,Wakim MG,Wei A,Parker MJ,Maslov MY,Pezone MJ,Tsukada H,Peterfreund RA

更新日期：2013-12-01 00:00:00

abstract：IMPLICATIONS:We report the successful use of the laryngeal mask airway for percutaneous endoscopic gastrostomy in an adult patient with a known difficult airway and severe cerebral palsy. ...

journal_title：Anesthesia and analgesia

authors： Brimacombe J,Newell S,Bergin A,McCarthy J,Barry J

更新日期：2000-09-01 00:00:00

abstract：:This randomized, prospective clinical study investigated the effects of supplemental inspired oxygen on arterial hemoglobin desaturation and myocardial ischemia in premedicated patients who have critical coronary artery stenosis, identified predictors for these adverse events, and examined the temporal relationship be...

journal_title：Anesthesia and analgesia

authors： Kavanagh BP,Cheng DC,Sandler AN,Chung F,Lawson S,Ong D

更新日期：1993-05-01 00:00:00

abstract：UNLABELLED:Thiamylal, a chiral thiobarbiturate, is marketed as a racemic product. We studied the serum protein binding and microsomal metabolism of thiamylal enantiomers in vitro. The unbound fraction of R(+)-thiamylal was greater than that of S(-)-thiamylal. The analysis of binding data revealed that both enantiomers ...

journal_title：Anesthesia and analgesia

authors： Sueyasu M,Fujito K,Shuto H,Mizokoshi T,Kataoka Y,Oishi R

更新日期：2000-09-01 00:00:00

abstract：:The anesthesia machine check is an integral part of the anesthesiologist's daily routine. It is standard operating procedure to check the high- and low-pressure systems of the machine as well as other integral parts that are accessible. Many new anesthesia machines offer a self-testing capability, but older ones with ...

journal_title：Anesthesia and analgesia

authors： Ianchulev SA,Comunale ME

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:In this prospective observational study, we compared changes in cardiac index (CI) during fluid challenge using photoplethysmography (PPG; Nexfin™) (CIPPG) versus esophageal Doppler (ED) (CIED) in major noncardiac surgery patients. METHODS:Measurements were obtained when the attending anesthesiologist decid...

journal_title：Anesthesia and analgesia

authors： Blanié A,Soued M,Benhamou D,Mazoit JX,Duranteau J

更新日期：2016-02-01 00:00:00

abstract：:Outcomes after cardiac arrest remain poor more than a half a century after closed chest cardiopulmonary resuscitation (CPR) was first described. This review article is focused on recent insights into the physiology of blood flow to the heart and brain during CPR. Over the past 20 years, a greater understanding of hear...

journal_title：Anesthesia and analgesia

authors： Lurie KG,Nemergut EC,Yannopoulos D,Sweeney M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:A lighted stylet is an effective alternative to a direct laryngoscope and has been reported to be particularly useful in patients with difficult airways. A high Mallampati class indicates poor visibility of the oropharyngeal structures. Because a lighted stylet does not require direct oropharyngeal visualiza...

journal_title：Anesthesia and analgesia

authors： Rhee KY,Lee JR,Kim J,Park S,Kwon WK,Han S

更新日期：2009-04-01 00:00:00

abstract：:Experimental aspiration pneumonitis studies in general have focused on the pathogenesis of the acidic component of the lung injury, although the injury produced by the particulate component of gastric contents largely has been ignored. The present study compares the inflammatory potential of small gastric particles to...

journal_title：Anesthesia and analgesia

authors： Knight PR,Rutter T,Tait AR,Coleman E,Johnson K

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Hypotension after spinal anesthesia for cesarean delivery is common. Previous studies have demonstrated that a crystalloid fluid "coload" (rapid administration of a fluid bolus starting at the time of intrathecal injection) is superior to the conventional crystalloid preload (fluid administered before the in...

journal_title：Anesthesia and analgesia

authors： Siddik-Sayyid SM,Nasr VG,Taha SK,Zbeide RA,Shehade JM,Al Alami AA,Mokadem FH,Abdallah FW,Baraka AS,Aouad MT

更新日期：2009-10-01 00:00:00

abstract：:The serotonergic system is involved in pain transmission and the 5-hydroxytryptamine (5-HT3) receptor subtype mediates some of these effects at the spinal level. Therefore, we explored the effects of the serotonergic system on nifedipine-induced analgesia by using the 5-HT3 receptor antagonist ondansetron. Male Spragu...

journal_title：Anesthesia and analgesia

authors： Hunt TE,Wu W,Zbuzek VK

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:High-quality shared decision-making for patients undergoing elective surgical procedures includes eliciting patient goals and treatment preferences. This is particularly important, should complications occur and life-sustaining therapies be considered. Our objective was to determine the preoperative care pre...

journal_title：Anesthesia and analgesia

authors： Udelsman BV,Govea N,Cooper Z,Chang DC,Bader A,Meyer MJ

更新日期：2021-01-01 00:00:00

abstract：UNLABELLED:We compared, in a double-blinded manner, the anesthetic maintenance and recovery properties of remifentanil with a clinically comparable fentanyl-based anesthetic technique in pediatric ambulatory surgical patients. Anesthesia was induced with either halothane or sevoflurane and nitrous oxide and oxygen. Pat...

journal_title：Anesthesia and analgesia

authors： Davis PJ,Finkel JC,Orr RJ,Fazi L,Mulroy JJ,Woelfel SK,Hannallah RS,Lynn AM,Kurth CD,Moro M,Henson LG,Goodman DK,Decker MD

更新日期：2000-04-01 00:00:00

abstract：:A microelectrode examination of guinea pig left ventricular papillary muscle was performed to determine whether there was a direct effect of pancuronium on cardiac cells and, if so, to attempt to ascertain the mechanism of this effect. Electrical events were measured before and during superfusion with pancuronium, epi...

journal_title：Anesthesia and analgesia

authors： Jacobs HK,Lim S,Salem MR,Rao TL,Mathru M,Smith BD

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:The switch from International Classification of Diseases, Ninth Revision, Clinical Modification to International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) for coding of inpatient procedures in the United States increased the number of procedural codes more than 19-fold,...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,O'Neill L

更新日期：2019-06-01 00:00:00

abstract：:There has been no description of the hemodynamic dose-response relationship between halothane and sodium nitroprusside (SNP), although these drugs are used together frequently for induction of deliberate hypotension. Utilizing aortic root cannulation and thermister-tipped pulmonary artery catheterization, this relatio...

journal_title：Anesthesia and analgesia

authors： Bedford RF

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Superoxide, nitric oxide (NO), and peroxynitrite are important mediators in the pathogenesis of ischemia-reperfusion (I/R) injury. We tested the renoprotective effects of allopurinol (ALP), a xanthine oxidase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), and 5,10,15,20-tetrakis (N-methyl-4-pyridyl) po...

journal_title：Anesthesia and analgesia

authors： Choi EK,Jung H,Kwak KH,Yi SJ,Lim JA,Park SH,Park JM,Kim S,Jee DL,Lim DG

更新日期：2017-01-01 00:00:00

abstract：UNLABELLED:Carpal tunnel release is often performed as an outpatient procedure. We designed this retrospective study to assess the effect of different anesthesia techniques on intraoperative cardiovascular stability and discharge time. According to the anesthesia technique received, 62 consecutive patients were categor...

journal_title：Anesthesia and analgesia

authors： Gebhard RE,Al-Samsam T,Greger J,Khan A,Chelly JE

更新日期：2002-08-01 00:00:00

abstract：UNLABELLED:We evaluated the effects of aggressive warming and maintenance of normothermia on surgical blood loss and allogeneic transfusion requirement. We randomly assigned 150 patients undergoing total hip arthroplasty with spinal anesthesia to aggressive warming (to maintain a tympanic membrane temperature of 36.5 d...

journal_title：Anesthesia and analgesia

authors： Winkler M,Akça O,Birkenberg B,Hetz H,Scheck T,Arkiliç CF,Kabon B,Marker E,Grübl A,Czepan R,Greher M,Goll V,Gottsauner-Wolf F,Kurz A,Sessler DI

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Even though current perception threshold (CPT) has been used for evaluating the effectiveness of sensory block in patients before surgery, its reliability under controlled conditions has not been investigated. Two independent investigations were performed. The primary objective of the first study was to dete...

journal_title：Anesthesia and analgesia

authors： Gaudreault F,Drolet P,Fallaha M,Varin F

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:There are profound racial and ethnic disparities in obstetric outcomes in the United States, but little is known about disparities in risk of postpartum hemorrhage (PPH). We explored the association of race and ethnicity on the risk of PPH due to uterine atony with sequential adjustment for possible mediatin...

journal_title：Anesthesia and analgesia

authors： Bryant A,Mhyre JM,Leffert LR,Hoban RA,Yakoob MY,Bateman BT

更新日期：2012-11-01 00:00:00

abstract：:The effects of adenosine-induced hypotension on central as well as myocardial hemodynamics and metabolism were studied in five neurolept-anesthetized patients without known heart or lung diseases, who were undergoing cerebral aneurysm surgery. Adenosine (217 +/- 32 micrograms.kg-1.min-1) decreased mean arterial pressu...

journal_title：Anesthesia and analgesia

authors： Owall A,Lagerkranser M,Sollevi A

更新日期：1988-03-01 00:00:00

abstract：:Lidocaine decreases the minimum alveolar concentration (MAC) of inhaled anesthetics and has been used clinically to reduce the requirements for other anesthetic drugs. In this study we examined the effects of lidocaine on isoflurane MAC in cats. Six cats were studied. In Experiment 1, the MAC of isoflurane was determi...

journal_title：Anesthesia and analgesia

authors： Pypendop BH,Ilkiw JE

更新日期：2005-01-01 00:00:00

abstract：UNLABELLED:We performed this study to assess the influence of endotracheal tube (ETT) tip design (Murphy-tip versus Magill-tip) on nasal trauma during nasotracheal intubation with a conventional polyvinyl chloride ETT. Patients were randomly allocated to one of four groups (n = 25 each): Magill-tipped ETT and Murphy-ti...

journal_title：Anesthesia and analgesia

authors： Lee JH,Kim CH,Bahk JH,Park KS

更新日期：2005-10-01 00:00:00