Prolonged Duration Local Anesthesia by Combined Delivery of Capsaicin- and Tetrodotoxin-Loaded Liposomes.

abstract：:Morphine given intracerebroventricularly releases spinal dynorphin A (Dyn) in mice. The present study was undertaken to determine whether morphine given intrathecally (IT) released Dyn. We demonstrated that the antinociceptive action of morphine was enhanced by procedures that are known to attenuate Dyn action. First,...

journal_title：Anesthesia and analgesia

authors： Holmes BB,Fujimoto JM

更新日期：1993-12-01 00:00:00

abstract：UNLABELLED:We studied the effects of spinal cord stimulation (SCS) on postherpetic neuralgia (PHN). Data of 28 patients were prospectively investigated over a median period of 29 (quartiles 9--39) mo. In addition, four patients with acute herpes zoster (HZ) pain were studied simultaneously. After intractable pain for m...

journal_title：Anesthesia and analgesia

authors： Harke H,Gretenkort P,Ladleif HU,Koester P,Rahman S

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that MAC (the minimum alveolar concentration of an inhaled anesthetic that produces immobility in 50% of subjects exposed to noxious stimulation) for halothane directly correlates with the central nervous system concentration of Na+. However, those studies globally altered Na+ c...

journal_title：Anesthesia and analgesia

authors： Laster MJ,Zhang Y,Eger EI 2nd,Shnayderman D,Sonner JM

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Heart rate variability might predict arrhythmias after coronary artery bypass grafting. METHODS:Off-line processing of 10-min electrocardiogram recordings of consecutive patients provided R-R intervals for time domain, frequency domain, Poincaré, and point correlation analyses and subsequent association wit...

journal_title：Anesthesia and analgesia

authors： Chamchad D,Djaiani G,Jung HJ,Nakhamchik L,Carroll J,Horrow JC

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Cerebral cholinergic transmission plays a key role in cognitive function, and anticholinergic drugs administered during the perioperative phase are a hypothetical cause of postoperative cognitive dysfunction (POCD). We hypothesized that a perioperative increase in serum anticholinergic activity (SAA) is asso...

journal_title：Anesthesia and analgesia

authors： Rossi A,Burkhart C,Dell-Kuster S,Pollock BG,Strebel SP,Monsch AU,Kern C,Steiner LA

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:In this study, we hypothesized that leg positioning and distal tourniquet application, when compared with neutral positioning of the leg, alters the efficacy of sciatic nerve block performed by the double-stimulation technique. METHODS:Ninety randomized, consecutive, ASA physical status I to III patients un...

journal_title：Anesthesia and analgesia

authors： Sertoz N,Deniz MN,Ayanoglu HO

更新日期：2011-12-01 00:00:00

abstract：:When neuromuscular blockade becomes necessary in the intensive care unit, there are several options available in regard to both the drug and the mode of delivery (continuous versus intermittent administration). Despite extensive experience with intermediate acting drugs such as atracurium or vecuronium, these muscle r...

journal_title：Anesthesia and analgesia

authors： Tobias JD,Lynch A,McDuffee A,Garrett JS

更新日期：1995-07-01 00:00:00

abstract：:In this prospective randomized, double-blind study, we investigated the effect of ondansetron on the lidocaine subarachnoid block. Fifty-four male patients scheduled for transurethral surgery under subarachnoid anesthesia received oral ondansetron 4 mg the evening before surgery and 4 mg IV 15 min before subarachnoid ...

journal_title：Anesthesia and analgesia

authors： Fassoulaki A,Melemeni A,Zotou M,Sarantopoulos C

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:For emergent procedures, in-house teams are required for immediate patient care. However, for many procedures, there is time to bring in a call team from home without increasing patient morbidity. Anesthesia providers taking subspecialty or backup call from home are required to return to the hospital within ...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,Diez C,Potnuru P

更新日期：2019-11-01 00:00:00

abstract：UNLABELLED:We evaluated the effect of 1, 20, and 40 mL of epidural saline flush on recovery from lidocaine epidural anesthesia. Eight volunteers were studied for three study periods, each separated by 72 h. The volume of saline was randomized, and a new catheter was inserted for each study period. A standardized dose o...

journal_title：Anesthesia and analgesia

authors： Chan VW,Nazarnia S,Kaszas Z,Perlas A

更新日期：1999-10-01 00:00:00

abstract：:In this study we attempted to define the minimal dosage of alfentanil (AF) needed in combination with nitrous oxide to provide satisfactory anesthetic conditions for lower abdominal gynecologic surgery. General anesthesia was induced in 12 women with AF (150 micrograms X kg-1) and 66% N2O in O2. An infusion of AF was ...

journal_title：Anesthesia and analgesia

authors： Ausems ME,Hug CC Jr,de Lange S

更新日期：1983-11-01 00:00:00

abstract：:Clinical practice parameters have been published with greater frequency by professional societies and groups of experts. These publications run the gamut of practice standards, practice guidelines, consensus statements or practice advisories, position statements, and practice alerts. The definitions of these terms hav...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Joshi GP,Gan TJ,Vetter TR

更新日期：2019-12-01 00:00:00

abstract：:In order to evaluate the possible physiologic significance of intra- and postoperative hypotension, we monitored arterial blood pressure and heart rate continuously for 36 hr starting the night before and ending the morning after operation in 34 gynecologic patients. The lowest pressures that occurred during physiolog...

journal_title：Anesthesia and analgesia

authors： Berger JJ,Donchin M,Morgan LS,van der Aa J,Gravenstein JS

更新日期：1984-07-01 00:00:00

abstract：:A study of the effects of halothane on the cyclic 3',5'-adenosine monophosphate (cAMP) system in human platelets was undertaken since cAMP has been implicated in the regulation of the process of platelet aggregation and this anesthetic has been reported to decrease platelet aggregation and, in other tissues, to increa...

journal_title：Anesthesia and analgesia

authors： Walter F,Vulliemoz Y,Verosky Y,Triner L

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Various different interventions can be used to reduce surgical blood loss; however, there is no "gold standard" for accurately measuring the volume of perioperative blood loss, and this makes it difficult to assess the efficacy of these interventions. METHODS:We used data from a previous multicenter double-...

journal_title：Anesthesia and analgesia

authors： Lopez-Picado A,Albinarrate A,Barrachina B

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:We implemented a previously described barcode-based drug safety system in all of our anesthetizing locations. Providers were instructed to scan the barcode on syringes using our Anesthesia Information Management System before drug administration, but the rate of provider adherence was low. We studied an impl...

journal_title：Anesthesia and analgesia

authors： Bowdle TA,Jelacic S,Nair B,Zucker F,Bussey LS,Togashi K,Yang JT,Lang J

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Lung-protective ventilation (LPV) has been demonstrated to improve clinical outcomes in surgical patients. There are very limited data on the current use of LPV for patients undergoing 1-lung ventilation (1LV) despite evidence that 1LV may be a particularly important setting for its use. In this multicenter ...

journal_title：Anesthesia and analgesia

authors： Colquhoun DA,Naik BI,Durieux ME,Shanks AM,Kheterpal S,Bender SP,Blank RS,MPOG Investigators.

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Clonidine is an alpha(2) adrenoreceptor and imidazoline receptor agonist, which has analgesic, sedative, and minimum alveolar anesthetic concentration-sparing effects. It has been used orally, IV, and epidurally. In spinal surgery, there is a reluctance to use local anesthetic-based epidural analgesia postop...

journal_title：Anesthesia and analgesia

authors： Farmery AD,Wilson-MacDonald J

更新日期：2009-02-01 00:00:00

abstract：UNLABELLED:We investigated the effects of approach (lateral versus anterior), position (supine versus Trendelenburg), and head rotation (0 degrees, 20 degrees, and maximum) during central venous catheterization on the area of the right internal jugular vein. Twenty-four patients were placed in supine position, followed...

journal_title：Anesthesia and analgesia

authors： Suarez T,Baerwald JP,Kraus C

更新日期：2002-12-01 00:00:00

abstract：:Either epidural analgesia or femoral nerve blockade improves analgesia and rehabilitation after total knee arthroplasty. No study has evaluated the combination of femoral nerve blockade and epidural analgesia. In this prospective, randomized, blinded study we investigated combining femoral nerve blockade with epidural...

journal_title：Anesthesia and analgesia

authors： YaDeau JT,Cahill JB,Zawadsky MW,Sharrock NE,Bottner F,Morelli CM,Kahn RL,Sculco TP

更新日期：2005-09-01 00:00:00

abstract：:Transesophageal Doppler (TED) monitoring provides continuous, noninvasive monitoring of cardiac output by measurement of aortic flow velocities. Because of the effects on aortic flow dynamics resulting from atherosclerosis, aortic cross-clamping, and wide variations in arterial blood pressure, the validity of TED moni...

journal_title：Anesthesia and analgesia

authors： Perrino AC Jr,Fleming J,LaMantia KR

更新日期：1991-12-01 00:00:00

abstract：:Twenty-four male patients scheduled for elective pulmonary resection were studied to determine whether continuous insufflation of oxygen to the nonventilated lung would reduce intrapulmonary shunting (Qs/Qt) and arterial oxygen desaturation. Measurements of physiologic variables were made using pulmonary arterial and ...

journal_title：Anesthesia and analgesia

authors： Rees DI,Wansbrough SR

更新日期：1982-06-01 00:00:00

abstract：:Patients with coronavirus disease 2019 (COVID-19) frequently experience a coagulopathy associated with a high incidence of thrombotic events leading to poor outcomes. Here, biomarkers of coagulation (such as D-dimer, fibrinogen, platelet count), inflammation (such as interleukin-6), and immunity (such as lymphocyte co...

journal_title：Anesthesia and analgesia

authors： Görlinger K,Dirkmann D,Gandhi A,Simioni P

更新日期：2020-11-01 00:00:00

abstract：:The relative safety of epidural catheter placement with subsequent heparinization has been well documented. However, what is the risk of neurologic sequelae in such patients who receive warfarin perioperatively? This study retrospectively evaluates the risk of spinal hematoma in patients receiving postoperative epidur...

journal_title：Anesthesia and analgesia

authors： Horlocker TT,Wedel DJ,Schlichting JL

更新日期：1994-07-01 00:00:00

abstract：:A microelectrode examination of guinea pig left ventricular papillary muscle was performed to determine whether there was a direct effect of pancuronium on cardiac cells and, if so, to attempt to ascertain the mechanism of this effect. Electrical events were measured before and during superfusion with pancuronium, epi...

journal_title：Anesthesia and analgesia

authors： Jacobs HK,Lim S,Salem MR,Rao TL,Mathru M,Smith BD

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:Through the Australian and New Zealand Haemostasis Registry, we report on the Australian and New Zealand experience with recombinant activated factor VII (rFVIIa) in obstetric patients. METHODS:The role of rFVIIa for off-label indications, including trauma, cardiac surgery, and severe postpartum hemorrhage, ...

journal_title：Anesthesia and analgesia

authors： Phillips LE,McLintock C,Pollock W,Gatt S,Popham P,Jankelowitz G,Ogle R,Cameron PA,Australian and New Zealand Haemostasis Registry.

更新日期：2009-12-01 00:00:00

abstract：UNLABELLED:Reports of transient neurological symptoms with the use of subarachnoid lidocaine has generated interest in alternate local anesthetics of intermediate duration, such as mepivacaine. This prospective randomized, double-blinded, dose-response study examined the anesthetic and recovery profiles of 60- and 80-m...

journal_title：Anesthesia and analgesia

authors： Pawlowski J,Sukhani R,Pappas AL,Kim KM,Lurie J,Gunnerson H,Corsino A,Frey K,Tonino P

更新日期：2000-09-01 00:00:00

abstract：:In view of the overall experience regarding regional anesthetic techniques to control postoperative pain in infants and children, it is feasible that a similar efficacy and safety profile can be obtained when using such techniques after major orthopedic procedures such as anterior or posterior spinal fusion. I reviewe...

journal_title：Anesthesia and analgesia

authors： Tobias JD

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Blood conservation strategies and transfusion guidelines remain a heavily debated clinical topic. Previous investigational trials have shown that acute isovolemic hemodilution does not limit adequate oxygen delivery; however, a true critical hemoglobin level has never been investigated or defined due to safe...

journal_title：Anesthesia and analgesia

authors： Sims CR 3rd,Delima LR,Calimaran A,Hester R,Pruett WA

更新日期：2018-01-01 00:00:00

abstract：:The hypothesis that neurogenically mediated cardiac arrhythmias can be induced by the intracerebroventrical (ICV) infusion of local anesthetic solutions was tested in 11 chronically prepared, unmedicated cats. Test substances were bupivacaine (0.1%), lidocaine (0.4%), procaine (0.4 or 0.8%), or saline (pH 5.8). Cats r...

journal_title：Anesthesia and analgesia

authors： Heavner JE

更新日期：1986-02-01 00:00:00