One-lung anesthesia: percent shunt and arterial oxygen tension during continuous insufflation of oxygen to the nonventilated lung.

Abstract:

:Twenty-four male patients scheduled for elective pulmonary resection were studied to determine whether continuous insufflation of oxygen to the nonventilated lung would reduce intrapulmonary shunting (Qs/Qt) and arterial oxygen desaturation. Measurements of physiologic variables were made using pulmonary arterial and peripheral arterial catheters. Blood was sampled for analysis and Qs/Qt and other hemodynamic variables were calculated. Significant differences were observed in Qs/Qt and arterial oxygen tensions (PaO2) between patients insufflated and those in whom oxygen was not insufflated. Patients with oxygen insufflation had significantly lower Qs/Qt and consistently higher PaO2. Statistically significant differences in Qs/Qt became apparent after 15, 30, and 45 minutes of one-lung ventilation compared with values for patients not receiving oxygen insufflation. Six of 12 patients without oxygen insufflation had peak Qs/Qt levels greater than 50%, whereas none of the patients in whom oxygen was insufflated had levels that exceeded this amount. Of 12 patients given oxygen insufflation, one had a PaO2 of less than 100 torr at the point of maximum decrease in arterial oxygen tension, compared with six of 12 patients in whom oxygen was not insufflated. These findings suggest that continuous oxygen insufflation of the nonventilated lung during periods of one-lung ventilation reduces Qs/Qt and minimizes arterial oxygen desaturation.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Rees DI,Wansbrough SR

subject

Has Abstract

pub_date

1982-06-01 00:00:00

pages

507-12

issue

6

eissn

0003-2999

issn

1526-7598

journal_volume

61

pub_type

杂志文章
  • Vasoconstrictors in spinal anesthesia with tetracaine--a comparison of epinephrine and phenylephrine.

    abstract::A randomized double-blind study was conducted in 50 orthopedic patients to determine the effect of epinephrine and phenylephrine on the anesthetic properties of intrathecally administered tetracaine. Two doses of each vasoconstrictor agent were studied: 0.2 mg of epinephrine, 0.3 mg of epinephrine, 1 mg of phenylephri...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Concepcion M,Maddi R,Francis D,Rocco AG,Murray E,Covino BG

    更新日期:1984-02-01 00:00:00

  • Gradual or abrupt nitrous oxide administration in a canine model of critical coronary stenosis induces regional myocardial dysfunction that is worsened by halothane.

    abstract::The existence of a dose-response relation between nitrous oxide concentration and regional dysfunction in compromised myocardium, and whether or not halothane-induced myocardial depression alleviated this regional dysfunction was examined. Nitrous oxide was administered to eight dogs with experimentally induced left a...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Leone BJ,Philbin DM,Lehot JJ,Foëx P,Ryder WA

    更新日期:1988-09-01 00:00:00

  • Dexamethasone added to lidocaine prolongs axillary brachial plexus blockade.

    abstract::Different additives have been used to prolong regional blockade. We designed a prospective, randomized, double-blind study to evaluate the effect of dexamethasone added to lidocaine on the onset and duration of axillary brachial plexus block. Sixty patients scheduled for elective hand and forearm surgery under axillar...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/01.ane.0000189055.06729.0a

    authors: Movafegh A,Razazian M,Hajimaohamadi F,Meysamie A

    更新日期:2006-01-01 00:00:00

  • The effect of fibrinogen substitution on reversal of dilutional coagulopathy: an in vitro model.

    abstract::Colloids and crystalloids are usually administered as treatment for hypovolemia in severely injured patients. However, dilution of clotting factors and platelets together with impaired fibrinogen polymerization are associated with fluid therapy and may aggravate hemorrhage, thus worsening final outcome of these patien...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000194359.06286.d4

    authors: Fries D,Innerhofer P,Reif C,Streif W,Klingler A,Schobersberger W,Velik-Salchner C,Friesenecker B

    更新日期:2006-02-01 00:00:00

  • The effect of electroconvulsive treatment on thermal hyperalgesia and mechanical allodynia in a rat model of peripheral neuropathy.

    abstract:UNLABELLED:We tested the ability of electroconvulsive treatment (ECT) to block thermal hyperalgesia and mechanical allodynia in rats with peripheral neuropathy. Repeated ECT (six times daily) significantly reduced thermal hyperalgesia 48 h after the end of the final treatment but had no significant effects on mechanica...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199803000-00028

    authors: Shibata M,Wakisaka S,Inoue T,Shimizu T,Yoshiya I

    更新日期:1998-03-01 00:00:00

  • Regional cerebral oxygen saturation during electroconvulsive therapy: monitoring by near-infrared spectrophotometry.

    abstract::Electroconvulsive therapy (ECT) increases neuronal energy consumption and alters systemic hemodynamics. We examined the effects of ECT on regional cerebral oxygen saturation (rSo2) using a near-infrared spectro-photometer. Heart rate (HR), mean arterial blood pressure (MAP), and rSo2 were continuously monitored throug...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199610000-00011

    authors: Saito S,Miyoshi S,Yoshikawa D,Shimada H,Morita T,Kitani Y

    更新日期:1996-10-01 00:00:00

  • An advanced specialty training program in anesthesiology: a special educational fellowship designed to return community anesthesiologists to clinical practice.

    abstract::We describe a program for community anesthesiologists designed to evaluate clinical skills and provide additional training in the latest technologies in anesthesiology. This educational program was established for previously trained anesthesiologists who require additional training for either remedial purposes or beca...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000220903.33100.15

    authors: Larson CP Jr,Steadman RH

    更新日期:2006-07-01 00:00:00

  • The effect of lidocaine on early postoperative cognitive dysfunction after coronary artery bypass surgery.

    abstract:UNLABELLED:We investigated the effect of lidocaine on the incidence of cognitive dysfunction in the early postoperative period after cardiac surgery. One-hundred-eighteen patients undergoing elective coronary artery bypass surgery with cardiopulmonary bypass (CPB) were randomized to receive either lidocaine (1.5 mg/kg ...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200211000-00002

    authors: Wang D,Wu X,Li J,Xiao F,Liu X,Meng M

    更新日期:2002-11-01 00:00:00

  • The discriminant power of simultaneous monitoring of spontaneous electroencephalogram and evoked potentials as a predictor of different clinical states of general anesthesia.

    abstract::Spontaneous or evoked electrical brain activity is increasingly used to monitor general anesthesia. Previous studies investigated the variables from spontaneous electroencephalogram (EEG), acoustic (AEP), or somatosensory evoked potentials (SSEP). But, by monitoring them separately, the available information from simu...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,多中心研究

    doi:10.1213/01.ane.0000237231.73261.92

    authors: Jeleazcov C,Schneider G,Daunderer M,Scheller B,Schüttler J,Schwilden H

    更新日期:2006-10-01 00:00:00

  • Renal function and proteinuria after cardiopulmonary bypass: the effects of temperature and mannitol.

    abstract::We studied three groups of patients without previous renal impairment, undergoing elective coronary artery bypass surgery. Group H (n = 7) underwent open heart surgery using moderate hypothermia (28 degrees C); Groups N and M (n = 8, each) were managed at normothermia. The extracorporeal circuit was primed with Hartma...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/00000539-199405000-00004

    authors: Ip-Yam PC,Murphy S,Baines M,Fox MA,Desmond MJ,Innes PA

    更新日期:1994-05-01 00:00:00

  • The efficacy of intrathecal morphine with or without clonidine for postoperative analgesia after radical prostatectomy.

    abstract:BACKGROUND:In this randomized study, we compared intrathecal (i.t.) morphine with or without clonidine and i.v. postoperative patient-controlled analgesia (PCA) morphine for analgesia after radical retropubic prostatectomy. METHODS:Fifty patients were randomly divided into three groups. They were allocated to receive ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ane.0b013e3181a30182

    authors: Andrieu G,Roth B,Ousmane L,Castaner M,Petillot P,Vallet B,Villers A,Lebuffe G

    更新日期:2009-06-01 00:00:00

  • A New Approach to Pathogen Containment in the Operating Room: Sheathing the Laryngoscope After Intubation.

    abstract:BACKGROUND:Anesthesiologists may contribute to postoperative infections by means of the transmission of blood and pathogens to the patient and the environment in the operating room (OR). Our primary aims were to determine whether contamination of the IV hub, the anesthesia work area, and the patient could be reduced af...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0000000000000854

    authors: Birnbach DJ,Rosen LF,Fitzpatrick M,Carling P,Arheart KL,Munoz-Price LS

    更新日期:2015-11-01 00:00:00

  • Dolasetron versus ondansetron for the treatment of postoperative nausea and vomiting.

    abstract::The management of postoperative nausea and vomiting (PONV) remains a persistent problem. Despite the use of prophylactic antiemetics, breakthrough nausea and vomiting still frequently occur. There have been no published studies comparing dolasetron and ondansetron for the treatment of PONV. This was a prospective, ran...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/01.ANE.0000144421.96275.D1

    authors: Meyer TA,Roberson CR,Rajab MH,Davis J,McLeskey CH

    更新日期:2005-02-01 00:00:00

  • Pharmacokinetics of lidocaine in nonpregnant and pregnant ewes.

    abstract::The pharmacokinetics of lidocaine were studied in nonpregnant and pregnant ewes. The maternal femoral vessels were cannulated and, on the day of study, the urinary bladder was catheterized. Lidocaine HCl, 4-5 mg/kg, was administered by IV injection over 60 seconds. Serial samples of arterial blood and urine were colle...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Santos AC,Pedersen H,Morishima HO,Finster M,Arthur GR,Covino BG

    更新日期:1988-12-01 00:00:00

  • Technical communication: new teaching model for practicing ultrasound-guided regional anesthesia techniques: no perishable food products!

    abstract:BACKGROUND:There is a pronounced learning curve for the technique of ultrasound-guided regional anesthesia. Practicing with a simulator model has been shown to speed the acquisition of these skills for various ultrasound-guided procedures. However, commercial models for ultrasound-guided regional anesthesia may be too ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3181cc558b

    authors: Liu Y,Glass NL,Power RW

    更新日期:2010-04-01 00:00:00

  • A comparison of the local anesthetic effects of meperidine, fentanyl, and sufentanil on dorsal root axons.

    abstract::The local anesthetic effects of opioids have been demonstrated in both clinical and laboratory studies. Clinically, both meperidine and sufentanil can produce segmental sensory anesthesia. However, previous studies of the effects of opioids on nerve conduction have all made use of peripheral nerve preparations and yie...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199610000-00021

    authors: Jaffe RA,Rowe MA

    更新日期:1996-10-01 00:00:00

  • Combination of ondansetron and droperidol in the prophylaxis of postoperative nausea and vomiting.

    abstract::The aim of this study was to compare the efficacy and safety of ondansetron plus droperidol with each drug alone or placebo in the prevention of postoperative nausea and vomiting (PONV). One hundred females, aged 18-65 yr, ASA physical status I-II, undergoing general anesthesia for elective abdominal surgery were incl...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-199607000-00021

    authors: Pueyo FJ,Carrascosa F,Lopez L,Iribarren MJ,García-Pedrajas F,Saez A

    更新日期:1996-07-01 00:00:00

  • Small-Volume Injections: Evaluation of Volume Administration Deviation From Intended Injection Volumes.

    abstract:BACKGROUND:In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000001976

    authors: Muffly MK,Chen MI,Claure RE,Drover DR,Efron B,Fitch WL,Hammer GB

    更新日期:2017-10-01 00:00:00

  • In vitro, inhibition of mitogen-activated protein kinase pathways protects against bupivacaine- and ropivacaine-induced neurotoxicity.

    abstract:BACKGROUND:Animal models show us that specific activation of the p38 mitogen-activated protein kinase (MAPK) may be a pivotal step in lidocaine neurotoxicity, but this has not been investigated in the case of two very widely used local anesthetics, bupivacaine and ropivacaine. We investigated the hypotheses that these ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e318168514b

    authors: Lirk P,Haller I,Colvin HP,Lang L,Tomaselli B,Klimaschewski L,Gerner P

    更新日期:2008-05-01 00:00:00

  • Anesthesia as therapy for persistent hiccups.

    abstract:IMPLICATIONS:Chronic hiccups may be a serious therapeutic problem. Pharmacological treatment with increasing dosages of baclofen, carbamazepine, or gabapentin is not always successful. In this paper, the use of general anesthesia with positive-pressure ventilation and muscle relaxation for the termination of chronic hi...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200208000-00050

    authors: Lierz P,Felleiter P

    更新日期:2002-08-01 00:00:00

  • Pulmonary gas exchange in coronary artery surgery patients during sevoflurane and isoflurane anesthesia.

    abstract:UNLABELLED:As the surgical population ages, the number of patients presenting with coronary artery disease and age-related loss of pulmonary recoil will increase. Although their influence on gas exchange in this population remains unknown, sevoflurane and isoflurane are used for an increasing variety of surgical proced...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200205000-00009

    authors: Loeckinger A,Keller C,Lindner KH,Kleinsasser A

    更新日期:2002-05-01 00:00:00

  • Effect of halothane and isoflurane on in situ diameter responses of small mesenteric veins to acute graded hypercapnia.

    abstract::The purpose of the present study was to quantify the inhibitory effect of inhaled halothane and isoflurane on acute hypercapnia-induced responses of capacitance-regulating veins and related cardiovascular variables in response to sequential 40-s periods of 5%, 10%, 15%, and 20% inspired CO2 (FICO2). Measurements were ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199602000-00024

    authors: Stekiel TA,Stekiel WJ,Tominaga M,Stadnicka A,Bosnjak ZJ,Kampine JP

    更新日期:1996-02-01 00:00:00

  • Time course of muscle relaxation with a combination of pancuronium and tubocurarine.

    abstract::A combination of pancuronium and d-tubocurarine is associated with potentiation of the neuromuscular blocking effects of each drug used singly. The time to onset of maximum block and the time to 25% recovery after administration of equipotent (ED95) doses of pancuronium (0.07 mg/kg) alone, d-tubocurarine (0.51 mg/kg) ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Mirakhur RK,Pandit SK,Ferres CJ,Gibson FM

    更新日期:1984-04-01 00:00:00

  • Supraventricular arrhythmias in intensive care unit patients: short and long-term consequences.

    abstract:BACKGROUND:Supraventricular arrhythmias (SVA), including atrial fibrillation and flutter, are common in surgical and nonsurgical intensive care unit (ICU) patients. There is increased mortality among surgical ICU patients who develop new-onset atrial arrhythmias after noncardiac, non-thoracic surgery. We sought to dete...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000255759.41131.05

    authors: Goodman S,Shirov T,Weissman C

    更新日期:2007-04-01 00:00:00

  • Are peripheral opioid antagonists the solution to opioid side effects?

    abstract:UNLABELLED:Opioid medication is the mainstay of therapy for severe acute and chronic pain. Unfortunately, the side effects of these medications can affect patient comfort and safety, thus limiting their proven therapeutic potential. Whereas the main analgesic effects of opioids are centrally mediated, many of the commo...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:10.1213/01.ane.0000090147.97636.77

    authors: Bates JJ,Foss JF,Murphy DB

    更新日期:2004-01-01 00:00:00

  • Comparison of Thrombelastography-Derived Fibrinogen Values at Rewarming and Following Cardiopulmonary Bypass in Cardiac Surgery Patients.

    abstract:BACKGROUND:The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest is factor I (fibrinogen). Hypofibrinogenemia is typically tested for using time-consumin...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1213/ANE.0000000000001465

    authors: Fabbro M 2nd,Gutsche JT,Miano TA,Augoustides JG,Patel PA

    更新日期:2016-09-01 00:00:00

  • Use of cognitive aids in a simulated anesthetic crisis.

    abstract::We evaluated empirically the extent to which the use of a cognitive aid during a high-fidelity simulation of a malignant hyperthermia (MH) event facilitated the correct and prompt treatment of MH. We reviewed the management of 48 simulated adult MH scenarios; 24 involving CA 1 and 24 involving CA 2 residents. In the C...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000229718.02478.c4

    authors: Harrison TK,Manser T,Howard SK,Gaba DM

    更新日期:2006-09-01 00:00:00

  • A new highly reliable instrument for the assessment of pre- and postoperative gynecological pain.

    abstract:UNLABELLED:In this study, we evaluated the reliability of a newly developed method for pain assessment, which is based on perceptual matching by Pain Matcher, Cefar Medical AB, Lund, Sweden, during minor gynecological surgery. In addition, the responsiveness to two different anesthetic methods-electro-acupuncture or a ...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200207000-00027

    authors: Stener-Victorin E,Kowalski J,Lundeberg T

    更新日期:2002-07-01 00:00:00

  • Bronchofiberscopic jet ventilation.

    abstract::The suction-biopsy channel of a flexible bronchofiberscope was used to provide subglottic jet ventilation in six dogs and eight adult human subjects. In dogs, after 75 minutes of ventilation at a driving pressure of 2580 torr/cm2 (50 lb/in2) the PaO2 was 412 +/- 18 torr and the PaCO2 32 +/- 3 torr with a peak airway p...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Satyanarayana T,Capan L,Ramanathan S,Chalon J,Turndorf H

    更新日期:1980-05-01 00:00:00

  • Readability, Content, and Quality Assessment of Web-Based Patient Education Materials Addressing Neuraxial Labor Analgesia.

    abstract:BACKGROUND:Studies in a variety of disciplines have shown that the readability of Web-based patient education materials is above that of the sixth grade reading level recommended by the U.S. Department of Health and Human Services. The aim of this study was to evaluate the readability, content, and quality of English- ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,多中心研究

    doi:10.1213/ANE.0000000000000888

    authors: Patel SK,Gordon EJ,Wong CA,Grobman WA,Goucher H,Toledo P

    更新日期:2015-11-01 00:00:00