The analgesic effect of epidural clonidine after spinal surgery: a randomized placebo-controlled trial.

abstract：UNLABELLED:Calcium-sensitizing drugs, such as levosimendan, are a novel class of drug therapy for heart failure. We investigated the hypothesis that levosimendan is a pulmonary vasodepressor mediated through inhibition of phosphodiesterase, adenosine triphosphate (ATP)-dependent potassium channels, or both. We investig...

journal_title：Anesthesia and analgesia

authors： De Witt BJ,Ibrahim IN,Bayer E,Fields AM,Richards TA,Banister RE,Kaye AD

更新日期：2002-06-01 00:00:00

abstract：:Forty neonates delivered by cesarean section were studied, half being delivered of mothers in whom anesthesia was induced with midazolam (0.3 mg/kg intravenously) and half of mothers given thiopental (4 mg/kg). At delivery, blood samples from mother and the umbilical vein were drawn for determination of plasma concent...

journal_title：Anesthesia and analgesia

authors： Bach V,Carl P,Ravlo O,Crawford ME,Jensen AG,Mikkelsen BO,Crevoisier C,Heizmann P,Fattinger K

更新日期：1989-03-01 00:00:00

abstract：UNLABELLED:Cryoanalgesia versus sham treatment was applied to the ilioinguinal and iliohypogastric nerves after mesh repair of an inguinal hernia under local anesthesia in 48 male patients in a prospective, randomized, and observer- and patient-blinded trial. Pain was scored daily during rest, while coughing, and durin...

journal_title：Anesthesia and analgesia

authors： Callesen T,Bech K,Thorup J,Andersen J,Nielsen R,Roikjaer O,Kehlet H

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Oral opioid formulations contribute to postoperative analgesia. In this study, we evaluated the perioperative application of oral controlled-release oxycodone to reduce postoperative IV morphine consumption and opioid side effects after lumbar discectomy. METHODS:Forty patients scheduled for elective lumbar...

journal_title：Anesthesia and analgesia

authors： Blumenthal S,Min K,Marquardt M,Borgeat A

更新日期：2007-07-01 00:00:00

abstract：:Inferential statistics relies heavily on the central limit theorem and the related law of large numbers. According to the central limit theorem, regardless of the distribution of the source population, a sample estimate of that population will have a normal distribution, but only if the sample is large enough. The rel...

journal_title：Anesthesia and analgesia

authors： Mascha EJ,Vetter TR

更新日期：2018-02-01 00:00:00

abstract：:In a prospective, randomized, double-blind study, we investigated whether epinephrine increased the efficacy of levobupivacaine and sufentanil during epidural labor analgesia. Seventy term parturients received an epidural injection of levobupivacaine 0.125% and sufentanil 0.75 microg/mL with or without 1:800,000 epine...

journal_title：Anesthesia and analgesia

authors： Soetens FM,Soetens MA,Vercauteren MP

更新日期：2006-07-01 00:00:00

abstract：UNLABELLED:Several factors are responsible for hypercarbia during laparoscopic procedures. This study was undertaken because we observed a sudden increase in PaCO(2) in children with portal hypertension (PHT), which was unusual in healthy children undergoing laparoscopic procedures. Fifty-seven children underwent lapar...

journal_title：Anesthesia and analgesia

authors： Bozkurt P,Kaya G,Yeker Y,Sarimurat N,Yesildag E,Tekant G,Emir H,Senyuz OF

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Statistical heterogeneity can increase the uncertainty of results and reduce the quality of evidence derived from systematic reviews. At present, it is uncertain what the major factors are that account for heterogeneity in meta-analyses of analgesic adjuncts. Therefore, the aim of this review was to identify...

journal_title：Anesthesia and analgesia

authors： Doleman B,Sutton AJ,Sherwin M,Lund JN,Williams JP

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:An anesthesia department implemented scheduling of anesthetics outside of operating rooms (non-OR) by clerks and nurses from other departments using its hospital's enterprise-wide scheduling system. METHODS:Observational studies chronicled the change over 2 yr as non-OR time was allocated by specialty, and ...

journal_title：Anesthesia and analgesia

authors： Dexter F,Xiao Y,Dow AJ,Strader MM,Ho D,Wachtel RE

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Previously, our group successfully established one of the nation's first Perioperative Surgical Homes (PSHs) aimed at coordinating services to patients undergoing primary total hip arthroplasty (THA) and primary total knee arthroplasty (TKA). As we now focus on extending the PSH to other service lines within...

journal_title：Anesthesia and analgesia

authors： Cyriac J,Garson L,Schwarzkopf R,Ahn K,Rinehart J,Vakharia S,Cannesson M,Kain Z

更新日期：2016-07-01 00:00:00

abstract：:We evaluated the effects of adding clonidine for continuous peripheral nerve infusions. Sixty patients undergoing total knee arthroplasty under combined single-injection sciatic block and continuous femoral infusion were randomly allocated to three groups: block induction with 0.75% ropivacaine followed by 0.2% ropiva...

journal_title：Anesthesia and analgesia

authors： Casati A,Vinciguerra F,Cappelleri G,Aldegheri G,Fanelli G,Putzu M,Chelly JE

更新日期：2005-03-01 00:00:00

abstract：:The respiratory variations in the plethysmographic (PLET) waveform of the pulse oximeter during mechanical ventilation can be automatically quantified as the PLET variation index (PVI(®)). Like other dynamic variables, the PVI may provide useful information about fluid responsiveness but only when the patient is recei...

journal_title：Anesthesia and analgesia

authors： Perel A

更新日期：2014-12-01 00:00:00

abstract：:The direct effect of protamine sulfate upon myocardial inotropism was studied using an isolated canine heart muscle preparation. Isometric force (F) was decreased to 87.6 +/- 1.2% of control values by a concentration of 50 x 10(-3) g/L protamine, which is approximately equal to the estimated serum concentration of pro...

journal_title：Anesthesia and analgesia

authors： Iwatsuki N,Matsukawa S,Iwatsuki K

更新日期：1980-02-01 00:00:00

abstract：:CO2 absorbents were introduced into anesthesia practice in 1924 and are essential when using a circle system to minimize waste by reducing fresh gas flow to allow exhaled anesthetic agents to be rebreathed. For many years, absorbent formulations consisted of calcium hydroxide combined with strong bases like sodium and...

journal_title：Anesthesia and analgesia

authors： Feldman JM,Hendrickx J,Kennedy RR

更新日期：2020-09-14 00:00:00

abstract：UNLABELLED:Using a randomized, double-blind protocol design, we compared a new lower-lipid emulsion of propofol (Ampofol) containing propofol 1%, soybean oil 5%, and egg lecithin 0.6% with the most commonly used formulation of propofol (Diprivan) with respect to onset of action and recovery profiles, as well as intraop...

journal_title：Anesthesia and analgesia

authors： Song D,Hamza M,White PF,Klein K,Recart A,Khodaparast O

更新日期：2004-03-01 00:00:00

abstract：:A 53-yr-old man undergoing laparoscopic cholecystectomy experienced cardiac arrest intraoperatively. Patient state index values decreased to single digits during the cardiac arrest and returned to baseline after successful cardiopulmonary resuscitation. ...

journal_title：Anesthesia and analgesia

authors： Nguyen NK,Lenkovsky F,Joshi GP

更新日期：2005-01-01 00:00:00

abstract：UNLABELLED:Whether tracheal intubation is more difficult in obese patients is debatable. We compared the incidence of difficult tracheal intubation in obese and lean patients by using a recently validated objective scale, the intubation difficulty scale (IDS). We studied 134 lean (body mass index, <30 kg/m2) and 129 ob...

journal_title：Anesthesia and analgesia

authors： Juvin P,Lavaut E,Dupont H,Lefevre P,Demetriou M,Dumoulin JL,Desmonts JM

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The spinal cord is an important site where volatile anesthetics decrease sensation and produce immobility. Beyond this knowledge, our understanding of a site of anesthetic action is limited. Previous evidence suggests that dorsal horn neurons with ascending projections may be more susceptible to depression b...

journal_title：Anesthesia and analgesia

authors： Barter LS,Mark LO,Jinks SL,Carstens EE,Antognini JF

更新日期：2008-03-01 00:00:00

abstract：:A combination of pancuronium and d-tubocurarine is associated with potentiation of the neuromuscular blocking effects of each drug used singly. The time to onset of maximum block and the time to 25% recovery after administration of equipotent (ED95) doses of pancuronium (0.07 mg/kg) alone, d-tubocurarine (0.51 mg/kg) ...

journal_title：Anesthesia and analgesia

authors： Mirakhur RK,Pandit SK,Ferres CJ,Gibson FM

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Pulmonary complications related to residual neuromuscular blockade lead to morbidity and mortality. Using an interrupted time series design, we tested whether proportions of reintubation for respiratory failure or new noninvasive ventilation were changed after a system-wide transition of the standard reversa...

journal_title：Anesthesia and analgesia

authors： Krause M,McWilliams SK,Bullard KJ,Mayes LM,Jameson LC,Mikulich-Gilbertson SK,Fernandez-Bustamante A,Bartels K

更新日期：2020-07-01 00:00:00

abstract：UNLABELLED:We examined the effects of two perioperative pain management techniques on recovery after laparotomy, as assessed by body weight (BW) and food consumption (FC). All rats received a preoperative intrathecal mixture of morphine plus bupivacaine combined with one of two treatments: (a) injection of slow-release...

journal_title：Anesthesia and analgesia

authors： Shavit Y,Fish G,Wolf G,Mayburd E,Meerson Y,Yirmiya R,Beilin B

更新日期：2005-10-01 00:00:00

abstract：:Persistent postoperative opioid use is thought to contribute to the ongoing opioid epidemic in the United States. However, efforts to study and address the issue have been stymied by the lack of a standard definition, which has also hampered efforts to measure the incidence of and risk factors for persistent postopera...

journal_title：Anesthesia and analgesia

authors： Kent ML,Hurley RW,Oderda GM,Gordon DB,Sun E,Mythen M,Miller TE,Shaw AD,Gan TJ,Thacker JKM,McEvoy MD,POQI-4 Working Group.

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Bilateral paravertebral block (PVB) is a suitable alternative to thoracic epidural analgesia (TEA) for abdominal surgeries. This randomized clinical trial aims to determine if PVB is noninferior to TEA in terms of analgesia after midline laparotomy. METHODS:Seventy American Society of Anesthesiologists (ASA...

journal_title：Anesthesia and analgesia

authors： Sondekoppam RV,Uppal V,Brookes J,Ganapathy S

更新日期：2019-09-01 00:00:00

abstract：UNLABELLED:We evaluated in a qualitative systematic review the effect of N-methyl-D-aspartate (NMDA) receptor antagonists on reducing postoperative pain and analgesic consumption beyond the clinical duration of action of the target drug (preventive analgesia). Randomized trials examining the use of an NMDA antagonist i...

journal_title：Anesthesia and analgesia

authors： McCartney CJ,Sinha A,Katz J

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:A single preoperative dose of 600 mg gabapentin, combined with multimodal analgesia, has previously been shown to reduce postcesarean pain and improve maternal satisfaction but was associated with increased maternal sedation. We hypothesized that a lower dose of gabapentin may be effective with less sedation...

journal_title：Anesthesia and analgesia

authors： Short J,Downey K,Bernstein P,Shah V,Carvalho JC

更新日期：2012-12-01 00:00:00

abstract：IMPLICATIONS:Postoperative management of sedation and analgesia in pediatric cardiac patients presents many challenges. This case report describes a child who experienced dramatic clinical improvement with the postoperative use of caudal morphine and clonidine after conventional therapy had failed. ...

journal_title：Anesthesia and analgesia

authors： Diaz LK,Cantu F

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:There is a considerable discrepancy between the reported incidences of awareness under anesthesia in children (0.2%-2.7%). In this prospective, observational, cohort study we evaluated 1) the incidence of awareness during general anesthesia in children across three settings, 2) factors contributing to awaren...

journal_title：Anesthesia and analgesia

authors： Malviya S,Galinkin JL,Bannister CF,Burke C,Zuk J,Popenhagen M,Brown S,Voepel-Lewis T

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Chronic pain is one of the most common complaints in patients with human immunodeficiency virus (HIV)-associated sensory neuropathy. Ryanodine receptor (RyR) and mitochondrial oxidative stress are involved in neuropathic pain induced by nerve injury. Here, we investigated the role of RyR and mitochondrial su...

journal_title：Anesthesia and analgesia

authors： Godai K,Takahashi K,Kashiwagi Y,Liu CH,Yi H,Liu S,Dong C,Lubarsky DA,Hao S

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which ...

journal_title：Anesthesia and analgesia

authors： Muffly MK,Chen MI,Claure RE,Drover DR,Efron B,Fitch WL,Hammer GB

更新日期：2017-10-01 00:00:00

abstract：UNLABELLED:Because succinylcholine has obvious advantages for facilitating endotracheal intubation in the ambulatory setting (e.g., low cost, fast onset, and no need for reversal of neuromuscular block), it is important to determine whether this muscle relaxant is indeed associated with an increased incidence of postop...

journal_title：Anesthesia and analgesia

authors： Mikat-Stevens M,Sukhani R,Pappas AL,Fluder E,Kleinman B,Stevens RA

更新日期：2000-08-01 00:00:00