The incidence of intraoperative awareness in children: childhood awareness and recall evaluation.

Abstract:

BACKGROUND:There is a considerable discrepancy between the reported incidences of awareness under anesthesia in children (0.2%-2.7%). In this prospective, observational, cohort study we evaluated 1) the incidence of awareness during general anesthesia in children across three settings, 2) factors contributing to awareness, and 3) short-term psychological effects of awareness. METHODS:Children (aged 5-15 yr) who underwent general anesthesia were included, and all perioperative data including anesthetic drugs were collected prospectively. Children were interviewed three times postoperatively using a semistructured questionnaire. All cases of possible or probable awareness were discussed with the child's care providers to confirm or refute the memories. Internal consensus among investigators across sites was reached, and these cases and a random selection of others were reviewed by three external reviewers. For the purpose of this study, possible/probable awareness was defined as cases with agreement between the internal consensus and at least two of the three external reviewers. RESULTS:One thousand seven hundred eighty-four children completed at least one interview. Thirty-two cases were coded as possible or probable awareness by at least one entity (i.e., either the internal consensus or one of the external reviewers). Fourteen of these cases met the definition for possible/probable awareness, making the incidence of awareness 0.8%. Six of the 14 children with awareness (43%) remembered feeling scared during their surgery and three (21%) reported hurting. Two children in this group (14%) said they would feel worse if they had to have surgery again, which was not significantly different from reports of children with no recall (15%). None of the children with awareness required psychological follow-up. Endoscopic procedures were associated with a higher risk for awareness (relative risk = 4.5 [confidence interval 1.5-13.6]). CONCLUSIONS:Although 0.8% of children experienced possible/probable awareness in this study, none experienced short-term psychological distress.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Malviya S,Galinkin JL,Bannister CF,Burke C,Zuk J,Popenhagen M,Brown S,Voepel-Lewis T

doi

10.1213/ANE.0b013e3181b620b0

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

1421-7

issue

5

eissn

0003-2999

issn

1526-7598

pii

ANE.0b013e3181b620b0

journal_volume

109

pub_type

杂志文章,多中心研究
  • Inhaled nitric oxide versus intravenous vasodilators in severe pulmonary hypertension after cardiac surgery.

    abstract:UNLABELLED:Inhaled nitric oxide (iNO) is superior to i.v. vasodilators for treatment of pulmonary hypertension (PH) after cardiac surgery, but iNO is a potentially toxic gas, and patient subsets who benefit from iNO are not yet clearly defined. We administered iNO 40 ppm, prostaglandin E1 (PGE1) 0.1 microg x kg(-1) min...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Schmid ER,Bürki C,Engel MH,Schmidlin D,Tornic M,Seifert B

    更新日期:1999-11-01 00:00:00

  • The anesthetic considerations in patients with ventricular assist devices presenting for noncardiac surgery: a review of eight cases.

    abstract:IMPLICATIONS:The number of patients supported by ventricular assist devices (VADs) that present for noncardiac surgery is increasing in our institution. Our recent experience with eight such patients is reported, along with a review of the most commonly implanted VADs and the anesthetic implications and considerations ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200207000-00007

    authors: Stone ME,Soong W,Krol M,Reich DL

    更新日期:2002-07-01 00:00:00

  • Radiologic assessment of potential sites for needle decompression of a tension pneumothorax.

    abstract:BACKGROUND:The recommended treatment of suspected tension pneumothorax is immediate needle decompression. Recommended sites and needle sizes for this procedure vary, and there are published reports of failed decompression as well as iatrogenic hemothorax. We investigated the optimal needle length and relative safety of...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000282827.86345.ff

    authors: Wax DB,Leibowitz AB

    更新日期:2007-11-01 00:00:00

  • The influence of propofol on vomiting induced by apomorphine.

    abstract::It has been proposed that propofol has antiemetic effects even in nonsedative doses. The aim of this study was to investigate whether propofol influences vomiting induced by the dopamine agonist apomorphine. Ten healthy male volunteers received apomorphine infusion (1 mg/min) until vomiting was induced on four differe...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-199505000-00019

    authors: Hvarfner A,Hammas B,Thörn SE,Wattwil M

    更新日期:1995-05-01 00:00:00

  • Comparison of morphine, meperidine, fentanyl, and sufentanil in balanced anesthesia: a double-blind study.

    abstract::A double-blind study comparing four narcotic analgesics of different potencies, meperidine, morphine, fentanyl, and sufentanil, was performed on consenting patients undergoing general or orthopedic surgery under balanced anesthesia. Blood pressure, measured through an indwelling arterial catheter, was recorded continu...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:

    authors: Flacke JW,Bloor BC,Kripke BJ,Flacke WE,Warneck CM,Van Etten AP,Wong DH,Katz RL

    更新日期:1985-09-01 00:00:00

  • The use of metoprolol and glycopyrrolate to prevent hypotensive/bradycardic events during shoulder arthroscopy in the sitting position under interscalene block.

    abstract:UNLABELLED:Sudden profound hypotensive and/or bradycardic events (HBE) have been reported in >20% of patients undergoing shoulder arthroscopy in the sitting position under interscalene block anesthesia. Retrospective studies suggest that the administration of beta-blockers is safe and may decrease the incidence of thes...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-199812000-00020

    authors: Liguori GA,Kahn RL,Gordon J,Gordon MA,Urban MK

    更新日期:1998-12-01 00:00:00

  • Benzodiazepines protect mice from local anesthetic convulsions and deaths.

    abstract::Median convulsant (CD50) and median lethal (LD50) doses of intraperitoneal lidocaine, bupivacaine, and etidocaine were determined in 149 mice. Another 496 mice were pretreated with intramuscular diazepam, lorazepam, or midazolam, 1 mg/kg. Fifteen minutes later, lidocaine, bupivacaine, or etidocaine was given intraperi...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: de Jong RH,Bonin JD

    更新日期:1981-06-01 00:00:00

  • Risk factors for neurologic deterioration after revascularization surgery in patients with moyamoya disease.

    abstract:UNLABELLED:To investigate the risk factors for postoperative neurological deterioration in patients with moyamoya disease, we retrospectively reviewed the perioperative course of 368 cases of revascularization surgery in 216 patients with this disease. Risk factors anecdotally associated with postoperative ischemic eve...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199711000-00018

    authors: Sakamoto T,Kawaguchi M,Kurehara K,Kitaguchi K,Furuya H,Karasawa J

    更新日期:1997-11-01 00:00:00

  • Effects of Intraoperative Opioid Use on Recurrence-Free and Overall Survival in Patients With Esophageal Adenocarcinoma and Squamous Cell Carcinoma.

    abstract:BACKGROUND:Perioperative opioid use is associated with poor survival in patients with esophageal squamous cell carcinoma. The most common histological type of esophageal cancer in western countries is adenocarcinoma. The objective of this study was to evaluate the association between intraoperative opioid consumption a...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000003428

    authors: Du KN,Feng L,Newhouse A,Mehta J,Lasala J,Mena GE,Hofstetter WL,Cata JP

    更新日期:2018-07-01 00:00:00

  • Bradykinin antagonists have no analgesic effect on incisional pain.

    abstract::Bradykinin, an endogenous nonapeptide and an important mediator of inflammation, is also implicated in the initiation and maintenance of pain. Both des-Arg(8), Leu(8)-bradykinin (dALBK) and HOE-140, the prototypic bradykinin B1 and B2 receptor antagonists, respectively, have been shown to reduce pain behaviors and inf...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ANE.0000130348.85587.BE

    authors: Leonard PA,Arunkumar R,Brennan TJ

    更新日期:2004-10-01 00:00:00

  • The antiallodynic effect of Neurotropin is mediated via activation of descending pain inhibitory systems in rats with spinal nerve ligation.

    abstract:BACKGROUND:Neurotropin, a nonprotein extract isolated from inflamed skin of rabbits inoculated with vaccinia virus, is widely used in Japan to treat chronic pain such as neuropathic pain. Although some studies have been conducted on the mechanism of the antiallodynic action of Neurotropin, this mechanism has yet to be ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e31817e7a59

    authors: Okazaki R,Namba H,Yoshida H,Okai H,Miura T,Kawamura M

    更新日期:2008-09-01 00:00:00

  • Outcomes in Patients Undergoing Cardiac Surgery Who Decline Transfusion and Received Erythropoietin Compared to Patients Who Did Not: A Matched Cohort Study.

    abstract:BACKGROUND:Erythropoiesis-stimulating agents, such as erythropoietin (EPO), can be used to treat preoperative anemia. Some studies suggest an increased risk of mortality and thrombotic events, and use in cardiovascular surgery remains off-label. This study compares outcomes in cardiac surgery patients declining blood t...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000002418

    authors: Duce L,Cooter ML,McCartney SL,Lombard FW,Guinn NR

    更新日期:2018-08-01 00:00:00

  • The effects of needle type, gauge, and tip bend on spinal needle deflection.

    abstract::Although the use of fine-gauge spinal needles reduces the incidence of postdural puncture headache, they are associated with increased risk of placement failure as a result of deflection and bending. This in vitro study quantifies spinal needle deflection from the axis of insertion with respect to needle type, gauge, ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199602000-00014

    authors: Sitzman BT,Uncles DR

    更新日期:1996-02-01 00:00:00

  • The dose-response of nitrous oxide in postoperative nausea in patients undergoing gynecologic laparoscopic surgery: a preliminary study.

    abstract:BACKGROUND:Whether nitrous oxide (N(2)O) increases the incidence of postoperative nausea and vomiting (PONV) after laparoscopic gynecologic surgery is still controversial, which may be due to the administration of different concentrations of inspired N(2)O. We investigated whether N(2)O results in a dose-response incre...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ane.0b013e318181f4aa

    authors: Mraovic B,Simurina T,Sonicki Z,Skitarelic N,Gan TJ

    更新日期:2008-09-01 00:00:00

  • Trends in the Prevalence of Intraoperative Adverse Events at Two Academic Hospitals After Implementation of a Mandatory Reporting System.

    abstract:BACKGROUND:Anesthesia information management systems (AIMSs) have been effectively used to improve quality in anesthesia care, and have enabled the development of mandatory quality assurance (QA) reporting systems for adverse events (AEs). While this approach has been shown to increase event reporting over time, the lo...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,多中心研究

    doi:10.1213/ANE.0000000000002447

    authors: Wanderer JP,Gratch DM,Jacques PS,Rodriquez LI,Epstein RH

    更新日期:2018-01-01 00:00:00

  • Case report: polyuria related to dexmedetomidine.

    abstract::Dexmedetomidine has become a popular sedative in the intensive care unit for patients undergoing mechanical ventilation because of its highly selective α-2 agonism, which exerts a combination of anesthetic, analgesic, and anxiolytic effects. Bradycardia and hypotension have been reported as the most common side effect...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3182917c86

    authors: Pratt A,Aboudara M,Lung L

    更新日期:2013-07-01 00:00:00

  • Comparison of desflurane with propofol in outpatients undergoing peripheral orthopedic surgery.

    abstract::This study was undertaken to compare desflurane with propofol anesthesia in outpatients undergoing peripheral orthopedic surgery. Data were combined from two institutions participating in a multicenter study. Ninety-one patients, ASA physical status I or II, were each randomly assigned to one of four groups. After adm...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/00000539-199210000-00019

    authors: Rapp SE,Conahan TJ,Pavlin DJ,Levy WJ,Hautman B,Lecky J,Luke J,Nessly ML

    更新日期:1992-10-01 00:00:00

  • The Effects of Continuous Positive Airway Pressure on Postoperative Outcomes in Obstructive Sleep Apnea Patients Undergoing Surgery: A Systematic Review and Meta-analysis.

    abstract:BACKGROUND:Obstructive sleep apnea (OSA) is a commonly encountered comorbid condition in patients undergoing surgery and is associated with a greater risk of postoperative adverse events. Our objective in this review was to investigate the effectiveness of continuous positive airway pressure (CPAP) in reducing the risk...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1213/ANE.0000000000000634

    authors: Nagappa M,Mokhlesi B,Wong J,Wong DT,Kaw R,Chung F

    更新日期:2015-05-01 00:00:00

  • Different responses of ear and finger pulse oximeter wave form to cold pressor test.

    abstract::The cold pressor test is often used to assess vasoconstrictive responses because it simulates the vasoconstrictive challenges commonly encountered in the clinical setting. With IRB approval, 12 healthy volunteers, aged 25--50 yr, underwent baseline plethysmographic monitoring on the finger and ear. The contralateral h...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000539-200106000-00026

    authors: Awad AA,Ghobashy MA,Ouda W,Stout RG,Silverman DG,Shelley KH

    更新日期:2001-06-01 00:00:00

  • Levobupivacaine-sufentanil with or without epinephrine during epidural labor analgesia.

    abstract::In a prospective, randomized, double-blind study, we investigated whether epinephrine increased the efficacy of levobupivacaine and sufentanil during epidural labor analgesia. Seventy term parturients received an epidural injection of levobupivacaine 0.125% and sufentanil 0.75 microg/mL with or without 1:800,000 epine...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1213/01.ane.0000221038.46094.c0

    authors: Soetens FM,Soetens MA,Vercauteren MP

    更新日期:2006-07-01 00:00:00

  • Estimation of optimal modeling weights for a Bayesian-based closed-loop system for propofol administration using the bispectral index as a controlled variable: a simulation study.

    abstract:BACKGROUND:Implementing Bayesian methods in a model-based closed-loop system requires the integration of a standard response model with a patient-specific response model. This process makes use of specific modeling weights, called Bayesian variances, which determine how the specific model can deviate from the standard ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000287269.06170.0f

    authors: De Smet T,Struys MM,Greenwald S,Mortier EP,Shafer SL

    更新日期:2007-12-01 00:00:00

  • Volume-independent elastance: a useful parameter for open-lung positive end-expiratory pressure adjustment.

    abstract:BACKGROUND:A decremental positive end-expiratory pressure (PEEP) trial after full lung recruitment allows for the adjustment of the lowest PEEP that prevents end-expiratory collapse (open-lung PEEP). For a tidal volume (Vt) approaching zero, the PEEP of minimum respiratory system elastance (PEEP(minErs)) is theoretical...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e31824a95ca

    authors: Carvalho AR,Bergamini BC,Carvalho NS,Cagido VR,Neto AC,Jandre FC,Zin WA,Giannella-Neto A

    更新日期:2013-03-01 00:00:00

  • Pulse contour analysis and transesophageal echocardiography: a comparison of measurements of cardiac output during laparoscopic colon surgery.

    abstract:BACKGROUND:Pulse wave analysis (PWA) allows cardiac output (CO) measurement after calibration by transpulmonary thermodilution. A PWA system that does not require previous calibration, the FloTrac/Vigileo (FTV), has been recently developed. We compared determinations of CO made with the FTV to simultaneous measurements...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e3181a491b8

    authors: Concha MR,Mertz VF,Cortínez LI,González KA,Butte JM

    更新日期:2009-07-01 00:00:00

  • Colloids versus crystalloids and tissue oxygen tension in patients undergoing major abdominal surgery.

    abstract:UNLABELLED:The effects of intravascular volume replacement regimens on tissue oxygen tension (ptiO(2)) are not definitely known. Forty-two consecutive patients scheduled for elective major abdominal surgery were prospectively randomized to receive either 6% hydroxyethyl starch (HES) (mean molecular weight 130 kd, degre...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验,收录出版

    doi:10.1097/00000539-200108000-00034

    authors: Lang K,Boldt J,Suttner S,Haisch G

    更新日期:2001-08-01 00:00:00

  • Pharyngeal Oxygen Insufflation During AirTraq Laryngoscopy Slows Arterial Desaturation in Infants and Small Children.

    abstract:BACKGROUND:The extent to which insufflation of oxygen into the posterior pharynx during laryngoscopy prolongs adequate saturation in infants and small children remains unknown. Therefore, we compared oxygen saturation over time in preoxygenated small children with and without posterior pharynx oxygen insufflation. MET...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000001189

    authors: Windpassinger M,Plattner O,Gemeiner J,Röder G,Baumann A,Zimmerman NM,Sessler DI

    更新日期:2016-04-01 00:00:00

  • Validating the Physiologic Model HumMod as a Substitute for Clinical Trials Involving Acute Normovolemic Hemodilution.

    abstract:BACKGROUND:Blood conservation strategies and transfusion guidelines remain a heavily debated clinical topic. Previous investigational trials have shown that acute isovolemic hemodilution does not limit adequate oxygen delivery; however, a true critical hemoglobin level has never been investigated or defined due to safe...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000002430

    authors: Sims CR 3rd,Delima LR,Calimaran A,Hester R,Pruett WA

    更新日期:2018-01-01 00:00:00

  • Comparison of a Novel Cadaver Model (Fix for Life) With the Formalin-Fixed Cadaver and Manikin Model for Suitability and Realism in Airway Management Training.

    abstract:BACKGROUND:Manikins are widely used in airway management training; however, simulation of realism and interpatient variability remains a challenge. We investigated whether cadavers embalmed with the novel Fix for Life (F4L) embalmment method are a suitable and realistic model for teaching 3 basic airway skills: facemas...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0000000000003678

    authors: van Emden MW,Geurts JJ,Schober P,Schwarte LA

    更新日期:2018-10-01 00:00:00

  • Choice of electrocardiography lead does not affect the usefulness of the T-wave criterion for detecting intravascular injection of an epinephrine test dose in anesthetized children.

    abstract:UNLABELLED:Accidental intravascular injection of an epinephrine-containing test dose increases T-wave amplitude of lead II electrocardiogram (EKG) in anesthetized children. We designed this study to test whether the choice of EKG lead would affect the usefulness of simulated intravascular test dose. We studied 32 ASA p...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/01.ane.0000070230.10328.08

    authors: Ogasawara K,Tanaka M,Nishikawa T

    更新日期:2003-08-01 00:00:00

  • The visual analog scale in the immediate postoperative period: intrasubject variability and correlation with a numeric scale.

    abstract:UNLABELLED:The visual analog scale (VAS) has been used to assess the efficacy of pain management regimens in patients with acute postoperative pain, but its usefulness has not been confirmed in postoperative pain studies. We studied 60 subjects in the immediate postoperative period. The specific data collected were: VA...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199801000-00020

    authors: DeLoach LJ,Higgins MS,Caplan AB,Stiff JL

    更新日期:1998-01-01 00:00:00

  • The effect of music on the neurohormonal stress response to surgery under general anesthesia.

    abstract:UNLABELLED:Several pharmacological interventions reduce perioperative stress hormone release during surgery under general anesthesia. Listening to music and therapeutic suggestions were also studied, but mostly in awake patients, and these have a positive effect on postoperative recovery and the need for analgesia. In ...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/01.ane.0000096182.70239.23

    authors: Migneault B,Girard F,Albert C,Chouinard P,Boudreault D,Provencher D,Todorov A,Ruel M,Girard DC

    更新日期:2004-02-01 00:00:00