Case report: polyuria related to dexmedetomidine.

Abstract:

:Dexmedetomidine has become a popular sedative in the intensive care unit for patients undergoing mechanical ventilation because of its highly selective α-2 agonism, which exerts a combination of anesthetic, analgesic, and anxiolytic effects. Bradycardia and hypotension have been reported as the most common side effects of its use in large studies. Dexmedetomidine has been reported to induce polyuria by suppressing vasopressin secretion and increasing permeability of the collecting ducts in a dose-dependent fashion. We report a case of dexmedetomidine-related polyuria that occurred with a high-dose continuous infusion and subsequently resolved with discontinuation of the drug. (Anesth Analg 2013;117:150-2).

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Pratt A,Aboudara M,Lung L

doi

10.1213/ANE.0b013e3182917c86

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

150-2

issue

1

eissn

0003-2999

issn

1526-7598

pii

ANE.0b013e3182917c86

journal_volume

117

pub_type

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