Midazolam-ethanol interactions and reversal with a benzodiazepine antagonist.

abstract：UNLABELLED:N-methyl-D-aspartate (NMDA) antagonists, such as MK801, delay the development of morphine tolerance. Magnesium, a noncompetitive NMDA antagonist, reduces postoperative morphine requirements. The present study was designed to evaluate the effects of intrathecal co-administration of magnesium sulfate with morp...

journal_title：Anesthesia and analgesia

authors： McCarthy RJ,Kroin JS,Tuman KJ,Penn RD,Ivankovich AD

更新日期：1998-04-01 00:00:00

abstract：:Informed consent for pediatric anesthesia challenges practitioners to navigate complex ethical, medical, and legal ambiguities. A patient's status as a minor does not negate the importance of his or her participation in the decision-making process but, rather, necessitates a nuanced evaluation of age and development t...

journal_title：Anesthesia and analgesia

authors： Feinstein MM,Pannunzio AE,Lobell S,Kodish E

更新日期：2018-12-01 00:00:00

abstract：:Recent determinations of the minimum alveolar anesthetic concentration (MAC) for nitrous oxide in rats yield values of 1.51-1.55 atm. When combined with results from other reports, these results suggest a deviation from linear additivity, and call into question the unitary theory of narcosis. The present report provid...

journal_title：Anesthesia and analgesia

authors： Gonsowski CT,Eger EI 2nd

更新日期：1994-10-01 00:00:00

abstract：UNLABELLED:The enhancing action of propofol on gamma-amino-n-butyric acid subtype A (GABA(A)) receptors purportedly underlies its anesthetic effects. However, a recent study found that a GABA(A) antagonist did not alter the capacity of propofol to depress the righting reflex. We examined whether the noncompetitive GABA...

journal_title：Anesthesia and analgesia

authors： Sonner JM,Zhang Y,Stabernack C,Abaigar W,Xing Y,Laster MJ

更新日期：2003-03-01 00:00:00

abstract：UNLABELLED:Transesophageal echocardiography (TEE) and central venous catheter (CVC) placement are often used during congenital cardiac surgery. Complications of CVC placement include cardiac perforation, inadvertent arterial placement, and erroneous hemodynamic data from unrecognized malposition. In this study, we used...

journal_title：Anesthesia and analgesia

authors： Andropoulos DB,Stayer SA,Bent ST,Campos CJ,Bezold LI,Alvarez M,Fraser CD

更新日期：1999-07-01 00:00:00

abstract：UNLABELLED:Intravenous and volatile general anesthetics inhibit norepinephrine (NE) release from sympathetic neurons and other neurosecretory cells. However, the actions of general anesthetics on NE release from central nervous system (CNS) neurons are unclear. We investigated the effects of representative IV and volat...

journal_title：Anesthesia and analgesia

authors： Pashkov VN,Hemmings HC Jr

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Sigma (sigma)-receptor agonists attenuate brain injury after experimental focal cerebral ischemia in several species. We tested the hypothesis that the potent, prototypical sigma(1)-receptor agonist, 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP), protects neurons by a mechanism involving the antiapoptotic pro...

journal_title：Anesthesia and analgesia

authors： Yang S,Bhardwaj A,Cheng J,Alkayed NJ,Hurn PD,Kirsch JR

更新日期：2007-05-01 00:00:00

abstract：:We determined the effects of hyperkalemia, hypernatremia, hyperosmolality and hypo-osmolality on halothane requirement (MAC) in dogs. Hyperkalemia did not change cerebrospinal fluid potassium or MAC. Hypernatremia proportionately increased cerebrospinal fluid sodium and osmolality. MAC concomitantly increased 43%. Ser...

journal_title：Anesthesia and analgesia

authors： Tanifuji Y,Eger EI 2nd

更新日期：1978-07-01 00:00:00

abstract：UNLABELLED:We conducted a randomized, controlled, cross-over cadaver study to test the hypothesis that the efficacy of seal for ventilation and airway protection, anatomic position, and airway patency with the flexible laryngeal mask airway (FLMA) are altered by the application of a Boyle Davis (B-D) gag. We also deter...

journal_title：Anesthesia and analgesia

authors： Brimacombe JR,Keller C,Gunkel AR,Pühringer F

更新日期：1999-07-01 00:00:00

abstract：UNLABELLED:We investigated the possibility of using argon, an inert gas, as a replacement for carbon dioxide (CO2). The tolerance of argon pneumoperitoneum was compared with that of CO2 pneumoperitoneum. Twenty pigs were anesthetized with enflurane 1.5%. Argon (n = 11) or CO2 (n = 9) pneumoperitoneum was created at 15 ...

journal_title：Anesthesia and analgesia

authors： Mann C,Boccara G,Grevy V,Navarro F,Fabre JM,Colson P

更新日期：1997-12-01 00:00:00

abstract：UNLABELLED:We investigated the impact of cardiopulmonary bypass pump (CPB), hematocrit, gender, age, and body weight on blood use in patients undergoing coronary artery bypass graft surgery at a major university hospital. Participants were 1235 consecutive patients undergoing primary coronary artery surgery over a peri...

journal_title：Anesthesia and analgesia

authors： Scott BH,Seifert FC,Glass PS,Grimson R

更新日期：2003-10-01 00:00:00

abstract：UNLABELLED:Endothelial dysfunction and platelet activation with thromboxane release may contribute to spasm or alterations in internal mammary artery (IMA) graft flow during coronary artery surgery. Clevidipine, an ultrashort-acting dihydropyridine calcium channel blocker, is undergoing clinical development, but there ...

journal_title：Anesthesia and analgesia

authors： Huraux C,Makita T,Szlam F,Nordlander M,Levy JH

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:The relatively short duration of effect of local anesthetics has been addressed by encapsulation in drug delivery systems. Codelivery with a single compound that produces an adjuvant effect on nerve block but without intrinsic local anesthetic properties can further prolong the nerve block effect. Here, we i...

journal_title：Anesthesia and analgesia

authors： Rwei AY,Sherburne RT,Zurakowski D,Wang B,Kohane DS

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:In patients with mitral regurgitation (MR), the effective regurgitant orifice area can be estimated by measuring the vena contracta area (VCA). We hypothesize that the VCA has characteristic temporal dynamics related to the underlying mechanism of functional mitral regurgitation (FMR) versus degenerative mit...

journal_title：Anesthesia and analgesia

authors： Cobey FC,Ashihkmina E,Edrich T,Fox J,Shook D,Bollen B,Breeze JL,Ursprung WW,Shernan SK

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:In the present study, we examined the effects and mechanisms of the Chinese herb resveratrol on attenuation of morphine tolerance in rats. METHODS:Male Wistar rats were implanted with 2 intrathecal catheters; one catheter was connected to a mini-osmotic pump, used for either morphine (15 μg/h) or saline (1 ...

journal_title：Anesthesia and analgesia

authors： Tsai RY,Chou KY,Shen CH,Chien CC,Tsai WY,Huang YN,Tao PL,Lin YS,Wong CS

更新日期：2012-10-01 00:00:00

abstract：:As most of us are aware, almost every facet of our society is becoming, for better or worse, progressively more technology-dependent. Technological advancement has made autonomous systems, also known as robots, an integral part of our life in several fields, including medicine. The application of robots in anesthesia ...

journal_title：Anesthesia and analgesia

authors： Zaouter C,Joosten A,Rinehart J,Struys MMRF,Hemmerling TM

更新日期：2020-05-01 00:00:00

abstract：:The purpose of this study was to determine the analgesic efficacy, opioid-sparing effect, and tolerability of ketorolac administered as an intravenous (i.v.) bolus followed by a continuous infusion after total hip or knee arthroplasty. After general anesthesia, patients received either placebo or ketorolac 30 mg i.v. ...

journal_title：Anesthesia and analgesia

authors： Etches RC,Warriner CB,Badner N,Buckley DN,Beattie WS,Chan VW,Parsons D,Girard M

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) is a commonly encountered comorbid condition in patients undergoing surgery and is associated with a greater risk of postoperative adverse events. Our objective in this review was to investigate the effectiveness of continuous positive airway pressure (CPAP) in reducing the risk...

journal_title：Anesthesia and analgesia

authors： Nagappa M,Mokhlesi B,Wong J,Wong DT,Kaw R,Chung F

更新日期：2015-05-01 00:00:00

abstract：:The extent of sensory and motor blockades was examined in 195 patients 5 and 20 min after four different techniques of brachial plexus block using 50 ml of 0.5% bupivacaine. The interscalene technique of Winnie (N = 50) resulted in a preferential blockade of the caudad portions of the cervical plexus and the cephalad ...

journal_title：Anesthesia and analgesia

authors： Lanz E,Theiss D,Jankovic D

更新日期：1983-01-01 00:00:00

abstract：:The hypnotic effects of propofol, midazolam, alfentanil, and their binary and triple combinations, were studied in 130 unpremedicated patients in a randomized, double-blind fashion. The ability to open eyes on verbal command was used as an end-point. Dose-response curves for the three drugs given separately and in com...

journal_title：Anesthesia and analgesia

authors： Vinik HR,Bradley EL Jr,Kissin I

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Multiple interventions have been tested in models of cardiopulmonary resuscitation (CPR) to optimize drug use, chest compressions, and ventilation. None has studied the effects of positive end-expiratory pressure (PEEP) on outcome. We hypothesized that because PEEP can reverse pulmonary atelectasis, lower pu...

journal_title：Anesthesia and analgesia

authors： McCaul C,Kornecki A,Engelberts D,McNamara P,Kavanagh BP

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:In this randomized study, we compared intrathecal (i.t.) morphine with or without clonidine and i.v. postoperative patient-controlled analgesia (PCA) morphine for analgesia after radical retropubic prostatectomy. METHODS:Fifty patients were randomly divided into three groups. They were allocated to receive ...

journal_title：Anesthesia and analgesia

authors： Andrieu G,Roth B,Ousmane L,Castaner M,Petillot P,Vallet B,Villers A,Lebuffe G

更新日期：2009-06-01 00:00:00

abstract：:The fragility of erythrocytes from 21 patients undergoing in vitro skeletal muscle contracture testing for malignant hyperthermia (MH) susceptibility was examined. Osmotic fragility was determined by the degree of hemolysis in buffered saline solutions of decreasing osmotic strength. Halothane-induced fragility was de...

journal_title：Anesthesia and analgesia

authors： Kistler P,Fletcher JE,Rosenberg H

更新日期：1987-10-01 00:00:00

abstract：:The traditional tests that have been used for the past 30 yr to determine plasma cholinesterase phenotype--measurement of esterase activity with a variety of substrates, dibucaine inhibition, fluoride inhibition, and Ro2-0683 inhibition--are inadequate for identifying some variants of this enzyme and leave many cases ...

journal_title：Anesthesia and analgesia

authors： Pantuck EJ

更新日期：1993-08-01 00:00:00

abstract：UNLABELLED:We studied the effects of spinal cord stimulation (SCS) on postherpetic neuralgia (PHN). Data of 28 patients were prospectively investigated over a median period of 29 (quartiles 9--39) mo. In addition, four patients with acute herpes zoster (HZ) pain were studied simultaneously. After intractable pain for m...

journal_title：Anesthesia and analgesia

authors： Harke H,Gretenkort P,Ladleif HU,Koester P,Rahman S

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Halothane and desflurane have been shown to attenuate neuronal injury; however, the effects of these anesthetics on mitochondria are unclear. We investigated whether halothane and desflurane affect the function of mitochondria after cerebral ischemia in rats. METHODS:Forty male Wistar rats were randomly div...

journal_title：Anesthesia and analgesia

authors： Zhang B,Wei X,Cui X,Zhou H,Ding W,Li W

更新日期：2008-04-01 00:00:00

abstract：UNLABELLED:We selected bis [N-(3,4-diacetoxybenzyl) tropanium-3alpha-yl] glutarate dibromide (TAAC3) from many new tropinyl diester derivatives to evaluate its neuromuscular blocking (NMB) and autonomic side effects on anesthetized rats, rabbits, guinea pigs, cats, pigs, dogs, and monkeys. NMB potency, onset, recovery ...

journal_title：Anesthesia and analgesia

authors： Gyermek L,Lee C,Cho YM,Nguyen N,Tsai SK

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Aspirin-resistant platelet activation in whole blood is attributable to a transcellular pathway not detected by isolated platelet aggregometry. Aspirin resistance as defined by urinary thromboxane levels is associated with increased risk for myocardial infarction or cardiac death. Whole blood point-of-care a...

journal_title：Anesthesia and analgesia

authors： Carroll RC,Craft RM,Snider CC,Aligeti VR,Wortham DC

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Intraarticular (IA) local anesthetics are often used for the management and prevention of pain after arthroscopic knee surgery. Recently, IA tramadol was also used for the management of these patients. However, the IA combination of local anesthetic and tramadol has not been evaluated in arthroscopic outpati...

journal_title：Anesthesia and analgesia

authors： Zeidan A,Kassem R,Nahleh N,Maaliki H,El-Khatib M,Struys MM,Baraka A

更新日期：2008-07-01 00:00:00

abstract：:Outpatients undergoing minor diagnostic and therapeutic procedures associated with intermittent discomfort are frequently given bolus injections of intravenous opioid analgesics. In a group of 80 healthy women undergoing vaginal ovum pickup procedures, we evaluated patient-controlled administration of alfentanil using...

journal_title：Anesthesia and analgesia

authors： Zelcer J,White PF,Chester S,Paull JD,Molnar R

更新日期：1992-07-01 00:00:00