The effects of general anesthetics on norepinephrine release from isolated rat cortical nerve terminals.

abstract：BACKGROUND:Recently, there has been significant focus on the effects of anesthesia on the developing brain. Concern is heightened in children <3 years of age requiring lengthy and/or multiple anesthetics. Hypospadias correction is common in otherwise healthy children and may require both lengthy and repeated anesthetic...

journal_title：Anesthesia and analgesia

authors： Adler AC,Chandrakantan A,Sawires Y,Lee AD,Hart M,Koh CJ,Janzen NK,Austin PF,Andropoulos DB

更新日期：2019-12-09 00:00:00

abstract：:A quest for a systems-level neuroscientific basis of anesthetic-induced loss and return of consciousness has been in the forefront of research for the past 2 decades. Recent advances toward the discovery of underlying mechanisms have been achieved using experimental electrophysiology, multichannel electroencephalograp...

journal_title：Anesthesia and analgesia

authors： Hudetz AG,Mashour GA

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The spinal cord is an important site where volatile anesthetics decrease sensation and produce immobility. Beyond this knowledge, our understanding of a site of anesthetic action is limited. Previous evidence suggests that dorsal horn neurons with ascending projections may be more susceptible to depression b...

journal_title：Anesthesia and analgesia

authors： Barter LS,Mark LO,Jinks SL,Carstens EE,Antognini JF

更新日期：2008-03-01 00:00:00

abstract：IMPLICATIONS:These results indicate that fetal exposure to propofol can vary considerably depending on maternal plasma albumin concentration. A fractional change in the maternal protein binding of propofol can result in a relatively large difference in fetal exposure. ...

journal_title：Anesthesia and analgesia

authors： He YL,Seno H,Sasaki K,Tashiro C

更新日期：2002-05-01 00:00:00

abstract：:Phenomena seen in axons exposed to subblocking doses serve as the basis for interpreting clinical and behavioral observations during onset and recovery of peripheral nerve block. To delineate the changes in excitability and in impulse conduction caused by subblocking concentrations of local anesthetics (LAs) in myelin...

journal_title：Anesthesia and analgesia

authors： Raymond SA

更新日期：1992-12-01 00:00:00

abstract：:A randomized double-blind study was conducted in 50 orthopedic patients to determine the effect of epinephrine and phenylephrine on the anesthetic properties of intrathecally administered tetracaine. Two doses of each vasoconstrictor agent were studied: 0.2 mg of epinephrine, 0.3 mg of epinephrine, 1 mg of phenylephri...

journal_title：Anesthesia and analgesia

authors： Concepcion M,Maddi R,Francis D,Rocco AG,Murray E,Covino BG

更新日期：1984-02-01 00:00:00

abstract：:We describe a program for community anesthesiologists designed to evaluate clinical skills and provide additional training in the latest technologies in anesthesiology. This educational program was established for previously trained anesthesiologists who require additional training for either remedial purposes or beca...

journal_title：Anesthesia and analgesia

authors： Larson CP Jr,Steadman RH

更新日期：2006-07-01 00:00:00

abstract：:The effects of intravenously administered lidocaine on cough suppression in elderly patients over the age of 60 yr during tracheal intubation under general anesthesia were evaluated in two studies. In the first study, 100 patients received a placebo of either 0.5, 1.0, 1.5, or 2.0 mg/kg lidocaine intravenously 1 min b...

journal_title：Anesthesia and analgesia

authors： Yukioka H,Hayashi M,Terai T,Fujimori M

更新日期：1993-08-01 00:00:00

abstract：:Noma (cancrum oris) is a disease of poverty and malnutrition, which predominantly affects children younger than 10 years in developing countries. Although the majority of sufferers die of sepsis at the time of the initial infection, or of subsequent starvation due to severe trismus and an inability to eat, a small min...

journal_title：Anesthesia and analgesia

authors： Coupe MH,Johnson D,Seigne P,Hamlin B

更新日期：2013-07-01 00:00:00

abstract：IMPLICATIONS:Because of case reports of severe bronchospasm after the use of mivacurium, we used the Food and Drug Administration MedWatch database to determine the frequency of bronchospasm as an adverse event after the use of nondepolarizing muscle relaxants. ...

journal_title：Anesthesia and analgesia

authors： Bishop MJ,O'Donnell JT,Salemi JR

更新日期：2003-08-01 00:00:00

abstract：UNLABELLED:Chronic ingestion of small doses of ethanol protects the myocardium from ischemic damage. It was demonstrated that short-term administration of ethanol (SAE) enhances the recovery of stunned myocardium in acutely instrumented, anesthetized dogs. It is unclear whether this beneficial effect of SAE also occurs...

journal_title：Anesthesia and analgesia

authors： Weber TP,Hartlage MA,Rolf N,Booke M,Berendes E,Van Aken H,Meissner A

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor alpha (TNF-alpha) could trigger p38 mitogen-activated protein kinase (MAPK) activation. Conversely phosphorylated p38 (p-p38) could induce the upregulation of TNF-alpha. In this study, we examined the hypothesis that chronic constrictive injury (CCI) of the sciatic nerve could promote s...

journal_title：Anesthesia and analgesia

authors： Xu L,Huang Y,Yu X,Yue J,Yang N,Zuo P

更新日期：2007-12-01 00:00:00

abstract：:To compare the dose-response of remifentanil for tracheal intubation in infants and children, 32 healthy full-term infants and 32 children were anesthetized with 10 mug/kg glycopyrrolate and 4.0 mg/kg propofol and administered 1 of 4 doses of remifentanil (1.25, 1.50, 1.75, or 2.00 microg/kg) to facilitate tracheal in...

journal_title：Anesthesia and analgesia

authors： Crawford MW,Hayes J,Tan JM

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Opioids are frequently used in chronic pain management but are associated with significant morbidity and mortality in some patient populations. An important avenue for identifying complications-including serious or rare complications-is the study of closed malpractice claims. The present study is intended to...

journal_title：Anesthesia and analgesia

authors： Abrecht CR,Brovman EY,Greenberg P,Song E,Rathmell JP,Urman RD

更新日期：2017-11-01 00:00:00

abstract：:Clinical practice parameters have been published with greater frequency by professional societies and groups of experts. These publications run the gamut of practice standards, practice guidelines, consensus statements or practice advisories, position statements, and practice alerts. The definitions of these terms hav...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Joshi GP,Gan TJ,Vetter TR

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Sedation protocols, including the use of sedation scales and regular sedation stops, help to reduce the length of mechanical ventilation and intensive care unit stay. Because clinical assessment of depth of sedation is labor-intensive, performed only intermittently, and interferes with sedation and sleep, pr...

journal_title：Anesthesia and analgesia

authors： Haenggi M,Ypparila-Wolters H,Buerki S,Schlauri R,Korhonen I,Takala J,Jakob SM

更新日期：2009-09-01 00:00:00

abstract：:Sufentanil is a potent opioid that occasionally has been associated with hypotension. The mechanism behind this hypotension is unclear. We hypothesized that sufentanil had a direct effect on vascular smooth muscle to cause vasodilation. Sufentanil was infused into the brachial artery of 10 young, healthy volunteers at...

journal_title：Anesthesia and analgesia

authors： Ebert TJ,Ficke DJ,Arain SR,Holtz MN,Shankar H

更新日期：2005-12-01 00:00:00

abstract：:Ketanserin, a serotonin antagonist, was used to control blood pressure during cardiopulmonary bypass in 12 patients having cardiac surgery. The drug was administered as a 10 mg bolus followed by a continuous infusion of either 40, 80, or 120 mg/hr to maintain mean arterial blood pressure below 70 mm Hg. There were 16 ...

journal_title：Anesthesia and analgesia

authors： Lichtenthal PR,Wade LD,Rossi EC

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Both femoral and obturator nerve blocks have been suggested to be useful in relieving pain after total knee arthroplasty (TKA). We sought to compare their efficacy. METHODS:Sixty patients undergoing elective unilateral TKA under spinal anesthesia received in a randomized, double-blind manner a femoral, obtu...

journal_title：Anesthesia and analgesia

authors： Kardash K,Hickey D,Tessler MJ,Payne S,Zukor D,Velly AM

更新日期：2007-09-01 00:00:00

abstract：:A claim of superiority of one intervention over another often depends naturally on results from several outcomes of interest. For such studies the common practice of making conclusions about individual outcomes in isolation can be problematic. For example, an intervention might be shown to improve one outcome (e.g., p...

journal_title：Anesthesia and analgesia

authors： Mascha EJ,Turan A

更新日期：2012-06-01 00:00:00

abstract：:We determined the neuromuscular blockade of 0.2 mg. kg(-1) mivacurium at the diaphragm by using two new methods of electromyographic (EMG) monitoring and compared it with acceleromyography of the orbicularis oculi (OO) and the corrugator supercilii (CS) muscle. After the induction of anesthesia in 15 patients undergoi...

journal_title：Anesthesia and analgesia

authors： Hemmerling TM,Schmidt J,Wolf T,Hanusa C,Siebzehnruebl E,Schmitt H

更新日期：2001-01-01 00:00:00

abstract：:A number of cardiac arrests and severe hypotensive episodes have been witnessed associated with the intravenous infusion of fresh frozen plasma (FFP). To clarify the possible role of hypocalcemia, 28 thermally injured anesthetized pediatric patients with massive blood loss were studied to examine the cardiovascular re...

journal_title：Anesthesia and analgesia

authors： Coté CJ,Drop LJ,Hoaglin DC,Daniels AL,Young ET

更新日期：1988-02-01 00:00:00

abstract：UNLABELLED:We evaluated the effects of aggressive warming and maintenance of normothermia on surgical blood loss and allogeneic transfusion requirement. We randomly assigned 150 patients undergoing total hip arthroplasty with spinal anesthesia to aggressive warming (to maintain a tympanic membrane temperature of 36.5 d...

journal_title：Anesthesia and analgesia

authors： Winkler M,Akça O,Birkenberg B,Hetz H,Scheck T,Arkiliç CF,Kabon B,Marker E,Grübl A,Czepan R,Greher M,Goll V,Gottsauner-Wolf F,Kurz A,Sessler DI

更新日期：2000-10-01 00:00:00

abstract：:Spine surgery is associated with a wide range of surgical and anesthetic complications. Excessive cerebrospinal fluid leak can be a cause of cerebellar hemorrhage postoperatively. We report a 43-yr-old patient who had lumbar spine reexploration surgery complicated by a cerebrospinal fluid leak which led to cerebellar ...

journal_title：Anesthesia and analgesia

authors： Farag E,Abdou A,Riad I,Borsellino SR,Schubert A

更新日期：2005-02-01 00:00:00

abstract：:The intracranial and systemic hemodynamic effects of sufentanil (20 micrograms/kg) were studied in 10 mongrel dogs. Baseline anesthesia was maintained with 0.7% end-tidal isoflurane and 50% nitrous oxide in oxygen. Catheters were inserted for blood pressure measurement, arterial and sagittal sinus blood sampling, radi...

journal_title：Anesthesia and analgesia

authors： Werner C,Hoffman WE,Baughman VL,Albrecht RF,Schulte J

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:We have developed a proportional-integral-derivative controller allowing the closed-loop coadministration of propofol and remifentanil, guided by a Bispectral Index (BIS) monitor, during induction and maintenance of general anesthesia. The controller was compared with manual target-controlled infusion. METH...

journal_title：Anesthesia and analgesia

authors： Liu N,Chazot T,Hamada S,Landais A,Boichut N,Dussaussoy C,Trillat B,Beydon L,Samain E,Sessler DI,Fischler M

更新日期：2011-03-01 00:00:00

abstract：:This study examined the changes in spinal and cortical evoked potentials (EPs) produced by fentanyl in the rabbit. The reversibility of these effects by naloxone and the effects of varying stimulus intensity also were examined. Eleven ketamine-anesthetized rabbits underwent analysis of spinal and cortical EPs produced...

journal_title：Anesthesia and analgesia

authors： Lee VC

更新日期：1994-02-01 00:00:00

abstract：:Patients receiving metoprolol before cardiac revascularization surgery were randomly divided into those in whom metoprolol was discontinued before the operation (N = 10) and those in whom metoprolol was continued up to the time of operation (N = 10). Cardiovascular responses to neuroleptanesthesia and sternotomy were ...

journal_title：Anesthesia and analgesia

authors： Pontén J,Häggendal J,Milocco I,Waldenström A

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that MAC for isoflurane directly correlates with the concentration of Na(+) in cerebrospinal fluid surrounding the spinal cord, the primary site for mediation of the immobility produced by inhaled anesthetics. If this correlation resulted from increased irritability of the cord,...

journal_title：Anesthesia and analgesia

authors： Shnayderman D,Laster MJ,Eger EI 2nd,Oh I,Zhang Y,Jinks SL,Antognini JF,Raines DE

更新日期：2008-09-01 00:00:00

abstract：:Rapid sequence induction and intubation (RSII) and awake tracheal intubation are commonly used anesthetic techniques in patients at risk of pulmonary aspiration of gastric or esophageal contents. Some of these patients may have a gastric tube (GT) placed preoperatively. Currently, there are no guidelines regarding whi...

journal_title：Anesthesia and analgesia

authors： Salem MR,Khorasani A,Saatee S,Crystal GJ,El-Orbany M

更新日期：2014-03-01 00:00:00