The influence of p38 mitogen-activated protein kinase inhibitor on synthesis of inflammatory cytokine tumor necrosis factor alpha in spinal cord of rats with chronic constriction injury.

abstract：:Recent determinations of the minimum alveolar anesthetic concentration (MAC) for nitrous oxide in rats yield values of 1.51-1.55 atm. When combined with results from other reports, these results suggest a deviation from linear additivity, and call into question the unitary theory of narcosis. The present report provid...

journal_title：Anesthesia and analgesia

authors： Gonsowski CT,Eger EI 2nd

更新日期：1994-10-01 00:00:00

abstract：UNLABELLED:Incorrect positioning of central venous catheters (CVC) in infants and children may lead to serious complications such as perforation of the heart or great vessels. CVC position is not usually assessed until the first postoperative chest radiograph, potentially leaving malposition undetected for several hour...

journal_title：Anesthesia and analgesia

authors： Andropoulos DB,Bent ST,Skjonsby B,Stayer SA

更新日期：2001-10-01 00:00:00

abstract：:Part I of this review discussed the similarities between embryogenesis, mammalian adaptions to hypoxia (primarily driven by hypoxia-inducible factor-1 [HIF-1]), ischemia-reperfusion injury (and its relationship with reactive oxygen species), hibernation, diving animals, cancer, and sepsis, and it focused on the common...

journal_title：Anesthesia and analgesia

authors： Thiele RH

更新日期：2017-06-01 00:00:00

abstract：:The aim of the present study was to investigate the impact of isoflurane on regional neurogenic mechanisms in the control of vascular tone. Therefore, regional determinations of sympathetic activity and hemodynamics were made in chloralose-anesthetized swine before and during administration of 1.4% isoflurane. Sympath...

journal_title：Anesthesia and analgesia

authors： Aneman A,Pontén J,Fändriks L,Eisenhofer G,Friberg P,Biber B

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Midazolam is the most commonly used premedication in children. It has been shown to be more effective than parental presence or placebo in reducing anxiety and improving compliance at induction of anesthesia. Clonidine, an alpha(2) agonist, has been suggested as an alternative. Dexmedetomidine is a more alph...

journal_title：Anesthesia and analgesia

authors： Yuen VM,Hui TW,Irwin MG,Yuen MK

更新日期：2008-06-01 00:00:00

abstract：IMPLICATIONS:The performance of regional blockade on a patient with a preexisting neurologic condition or a history of neurologic complications after regional anesthesia is controversial. We present a case of recurring brachial plexus neuropathy in a diabetic patient after two shoulder procedures performed 4 mo apart. ...

journal_title：Anesthesia and analgesia

authors： Horlocker TT,O'Driscoll SW,Dinapoli RP

更新日期：2000-09-01 00:00:00

abstract：:The dorsal raphe (DR) nucleus is a system of nuclei in the midline of the lower brainstem, which is considered one of the most important nuclei in the modulation of pain in the central nervous system. Central noradrenergic systems play an important role in the control of cardiovascular regulation and pain transmission...

journal_title：Anesthesia and analgesia

authors： Alojado ME,Ohta Y,Kemmotsu O

更新日期：1994-08-01 00:00:00

abstract：:Tramadol analgesia results from a monoaminergic effect by tramadol itself and an opioid effect of its metabolite (+)-M1 formed by O-demethylation of tramadol by CYP2D6. In this study we sought to determine the impact of (+)-M1 on the analgesic effect of tramadol evaluated by experimental pain models. The effect of an ...

journal_title：Anesthesia and analgesia

authors： Enggaard TP,Poulsen L,Arendt-Nielsen L,Brøsen K,Ossig J,Sindrup SH

更新日期：2006-01-01 00:00:00

abstract：UNLABELLED:Accidental intravascular injection of an epinephrine-containing test dose increases T-wave amplitude of lead II electrocardiogram (EKG) in anesthetized children. We designed this study to test whether the choice of EKG lead would affect the usefulness of simulated intravascular test dose. We studied 32 ASA p...

journal_title：Anesthesia and analgesia

authors： Ogasawara K,Tanaka M,Nishikawa T

更新日期：2003-08-01 00:00:00

abstract：UNLABELLED:We conducted this retrospective study to document the efficacy and safety, and demonstrate the spectrum of indications for subcutaneously tunneled epidural catheters in the management of prolonged pain in pediatric patients. The charts of 25 patients with prolonged pain that was unresponsive to conventional ...

journal_title：Anesthesia and analgesia

authors： Aram L,Krane EJ,Kozloski LJ,Yaster M

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Patients with lung failure who undergo prone positioning often receive extended hemodynamic monitoring. We investigated the influence of modified prone positioning (135°) on the accuracy of pulse contour-derived calibrated cardiac index (CIPC) and uncalibrated cardiac index (CIVIG) in this patient population...

journal_title：Anesthesia and analgesia

authors： Grensemann J,Bruecken U,Treszl A,Wappler F,Sakka SG

更新日期：2013-04-01 00:00:00

abstract：:We studied the feasibility of recording motor evoked responses to transcranial electrical stimulation (tce-MERs) during partial neuromuscular blockade (NMB). In 11 patients, compound muscle action potentials were recorded from the tibialis anterior muscle in response to transcranial electrical stimulation during vario...

journal_title：Anesthesia and analgesia

authors： Kalkman CJ,Drummond JC,Kennelly NA,Patel PM,Partridge BL

更新日期：1992-10-01 00:00:00

abstract：UNLABELLED:Thiopental is a racemate. In this study, we examined whether thiopental total body clearance and its distribution into central nervous system (CNS) tissue of rats was enantioselective. Rats, either anesthetized with halothane or conscious and restrained, were infused to stepwise steady-state targets of 5, 10...

journal_title：Anesthesia and analgesia

authors： Mather LE,Edwards SR,Duke CC,Cousins MJ

更新日期：1999-07-01 00:00:00

abstract：UNLABELLED:Propofol is a cardiac depressant with minimal diastolic effects in the adult myocardium. Cardiac effects of propofol in the newborn are unknown. We examined hemodynamic variables and systolic and diastolic left ventricular function in 12 newborn pigs exposed to propofol at three different infusion rates (7.5...

journal_title：Anesthesia and analgesia

authors： Graham MR,Thiessen DB,Mutch WA

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Noticeable changes in vital signs indicating hypovolemia occur only after 15% of the blood volume is lost. More sensitive variables (e.g., cardiac output, systolic pressure variation and its Δdown component) are invasive and difficult to obtain in the early phase of bleeding. Lately, a new technology for con...

journal_title：Anesthesia and analgesia

authors： Shamir MY,Kaplan L,Marans RS,Willner D,Klein Y

更新日期：2011-03-01 00:00:00

abstract：UNLABELLED:Propofol has an antiemetic effect that may be mediated by gamma-aminobutyric acid (GABA) influences on the serotonin system, the mechanism of which is not known. We used three techniques, immunohistochemistry, High Performance Liquid Chromatography, and electrophysiology, to define propofol's effects on the ...

journal_title：Anesthesia and analgesia

authors： Cechetto DF,Diab T,Gibson CJ,Gelb AW

更新日期：2001-04-01 00:00:00

abstract：:Computer simulations for the technique of estimating minimum alveolar anesthetic concentration (MAC) in patients (quantal design) suggest that incremental concentration changes and the number of crossovers affect MAC. We hypothesized that these variables may also apply to estimating MAC in rats (bracketing design). Th...

journal_title：Anesthesia and analgesia

authors： Leon A,Mayzler O,Benifla M,Semionov M,Fuxman Y,Eilig I,Passuga V,Doitchinova MK,Gurevich B,Artru AA,Shapira Y

更新日期：2004-12-01 00:00:00

abstract：UNLABELLED:We examined the effect of ulinastatin, a protease inhibitor purified from human urine, on neuromuscular block caused by vecuronium. Sixty adult patients were randomly divided into four groups of 15 patients each: ulinastatin-posttetanic count (U-PTC), ulinastatin-train-of-four (U-TOF), control-posttetanic co...

journal_title：Anesthesia and analgesia

authors： Saitoh Y,Fujii Y,Oshima T

更新日期：1999-12-01 00:00:00

abstract：UNLABELLED:We investigated the physiological reaction to mobilization the first and second day after aortic valve replacement in an open, prospective study. Hemodynamic and oxygenation variables were recorded in 15 patients using a pulmonary artery oximetry catheter and bench oximetry. Serious intraoperative events occ...

journal_title：Anesthesia and analgesia

authors： Kirkeby-Garstad I,Sellevold OF,Stenseth R,Skogvoll E,Karevold A

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:In this study, we examined the relationship between postoperative cognitive dysfunction (POCD) and intraoperative regional cerebral oxygen saturation (rSO2) in elderly patients undergoing spinal surgery. METHODS:We enrolled 87 patients older than 65 years. All patients were tested using a battery of cogniti...

journal_title：Anesthesia and analgesia

authors： Kim J,Shim JK,Song JW,Kim EK,Kwak YL

更新日期：2016-08-01 00:00:00

abstract：UNLABELLED:The objective of this study was to evaluate prognostic models for quality assurance purposes in predicting automatically detected intraoperative cardiovascular events (CVE) in 58458 patients undergoing noncardiac surgery. To this end, we assessed the performance of two established models for risk assessment ...

journal_title：Anesthesia and analgesia

authors： Röhrig R,Junger A,Hartmann B,Klasen J,Quinzio L,Jost A,Benson M,Hempelmann G

更新日期：2004-03-01 00:00:00

abstract：:Procaine hydrochloride was added to cardioplegia and studied for its efficacy in stabilizing the postischemic rhythm after aortic declamping in cardiac surgery. Fifty-six patients scheduled for coronary artery bypass grafting (CABG), were included in a randomized, double-blind study. The patients were anesthetized wit...

journal_title：Anesthesia and analgesia

authors： Sellevold OF,Berg EM,Levang OW

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Statistical heterogeneity can increase the uncertainty of results and reduce the quality of evidence derived from systematic reviews. At present, it is uncertain what the major factors are that account for heterogeneity in meta-analyses of analgesic adjuncts. Therefore, the aim of this review was to identify...

journal_title：Anesthesia and analgesia

authors： Doleman B,Sutton AJ,Sherwin M,Lund JN,Williams JP

更新日期：2018-02-01 00:00:00

abstract：IMPLICATIONS:Chronic hiccups may be a serious therapeutic problem. Pharmacological treatment with increasing dosages of baclofen, carbamazepine, or gabapentin is not always successful. In this paper, the use of general anesthesia with positive-pressure ventilation and muscle relaxation for the termination of chronic hi...

journal_title：Anesthesia and analgesia

authors： Lierz P,Felleiter P

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Neonatal exposure to sevoflurane induces neurobehavioral and neuroendocrine abnormalities in exposed male rats (generation F0) and neurobehavioral, but not neuroendocrine, abnormalities in their male, but not female, offspring (generation F1). These effects of sevoflurane are accompanied by a hypermethylated...

journal_title：Anesthesia and analgesia

authors： Xu N,Lei L,Lin Y,Ju LS,Morey TE,Gravenstein N,Yang J,Martynyuk AE

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Perineural dexamethasone has gained popularity in regional anesthesia to prolong analgesia duration. However, uncertainty remains regarding the optimal perineural dose. Clarification of this characteristic is of significant importance as the administration of dexamethasone may lead to dose-dependent complica...

journal_title：Anesthesia and analgesia

authors： Kirkham KR,Jacot-Guillarmod A,Albrecht E

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Percutaneous cricothyroidotomy may be a life-saving procedure in cannot intubate-cannot ventilate situations. In this study we compared the insertion times of a new indicator-guided cricothyroidotomy device and a wire-guided device in mannequins. METHODS:This study was a crossover trial comparing the insert...

journal_title：Anesthesia and analgesia

authors： Assmann NM,Wong DT,Morales E

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Because children's anxiety influences pain perception, perioperative anxiety should be evaluated in clinical practice with a unique, useful, and valid tool to optimize pain management. In this study, we evaluated psychometric properties of the visual analog scale (VAS)-anxiety for children and to study its p...

journal_title：Anesthesia and analgesia

authors： Bringuier S,Dadure C,Raux O,Dubois A,Picot MC,Capdevila X

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Anesthesiologists may contribute to postoperative infections by means of the transmission of blood and pathogens to the patient and the environment in the operating room (OR). Our primary aims were to determine whether contamination of the IV hub, the anesthesia work area, and the patient could be reduced af...

journal_title：Anesthesia and analgesia

authors： Birnbach DJ,Rosen LF,Fitzpatrick M,Carling P,Arheart KL,Munoz-Price LS

更新日期：2015-11-01 00:00:00

abstract：:A series of groups of Sprague-Dawley rats were given either secobarbital, phenobarbital, morphine, pentazocine, diazepam, methotrimeprazine, or saline (control) intraperitoneally on 4 consecutive days and then, on day 5, anesthetized with chloroform, trichlorethylene, fluroxene, halothane, methoxyflurane, enflurane, i...

journal_title：Anesthesia and analgesia

authors： Dobkin AB,Borgstedt HH,Rohner RF,KURLAN RM,Fein AB

更新日期：1975-01-01 00:00:00