The effect of clonidine on the activity of neurons in the rat dorsal raphe nucleus in vitro.

abstract：IMPLICATIONS:Tizanidine was given systemically to rats with experimental postoperative pain. Partial pain relief was obtained, but the effect was not clinically significant. Although systemic tizanidine is effective in relieving experimental neuropathic pain, it is not as effective for postoperative pain. ...

journal_title：Anesthesia and analgesia

authors： Hord AH,Denson DD,Azevedo MI

更新日期：2001-11-01 00:00:00

abstract：:The ex utero intrapartum treatment (EXIT) procedure provides time to secure the airway of the fetus while utero-placental circulation supplies the fetus with oxygen. We report the anesthetic management of a fetus with a large neck mass during an EXIT procedure in which the confirmation of correct endotracheal intubati...

journal_title：Anesthesia and analgesia

authors： Eschertzhuber S,Keller C,Mitterschiffthaler G,Jochberger S,Kühbacher G

更新日期：2005-09-01 00:00:00

abstract：UNLABELLED:We selected bis [N-(3,4-diacetoxybenzyl) tropanium-3alpha-yl] glutarate dibromide (TAAC3) from many new tropinyl diester derivatives to evaluate its neuromuscular blocking (NMB) and autonomic side effects on anesthetized rats, rabbits, guinea pigs, cats, pigs, dogs, and monkeys. NMB potency, onset, recovery ...

journal_title：Anesthesia and analgesia

authors： Gyermek L,Lee C,Cho YM,Nguyen N,Tsai SK

更新日期：2002-04-01 00:00:00

abstract：UNLABELLED:We performed this study to assess the influence of endotracheal tube (ETT) tip design (Murphy-tip versus Magill-tip) on nasal trauma during nasotracheal intubation with a conventional polyvinyl chloride ETT. Patients were randomly allocated to one of four groups (n = 25 each): Magill-tipped ETT and Murphy-ti...

journal_title：Anesthesia and analgesia

authors： Lee JH,Kim CH,Bahk JH,Park KS

更新日期：2005-10-01 00:00:00

abstract：:Because no completely effective antiemetic exists for the prevention of postoperative nausea and vomiting (PONV), we hypothesize that a multimodal approach to management of PONV may reduce both vomiting and the need for rescue antiemetics in high-risk patients. After IRB approval, women undergoing outpatient laparosco...

journal_title：Anesthesia and analgesia

authors： Scuderi PE,James RL,Harris L,Mims GR 3rd

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that MAC for isoflurane directly correlates with the concentration of Na(+) in cerebrospinal fluid surrounding the spinal cord, the primary site for mediation of the immobility produced by inhaled anesthetics. If this correlation resulted from increased irritability of the cord,...

journal_title：Anesthesia and analgesia

authors： Shnayderman D,Laster MJ,Eger EI 2nd,Oh I,Zhang Y,Jinks SL,Antognini JF,Raines DE

更新日期：2008-09-01 00:00:00

abstract：UNLABELLED:Our aim in this study, performed using a closed cranial window preparation, was to investigate the effect of systemic pretreatment with dexmedetomidine on cerebrovascular response to isoflurane or sevoflurane. After instrumentation under pentobarbital anesthesia, 48 dogs were assigned to one of two groups: t...

journal_title：Anesthesia and analgesia

authors： Ohata H,Iida H,Dohi S,Watanabe Y

更新日期：1999-08-01 00:00:00

abstract：UNLABELLED:In this randomized, controlled study in dogs, we examined the short-term effects of blood pressure targeted fluid resuscitation with colloids or crystalloids solutions on systemic oxygen delivery, and lactate blood concentration. Fluid resuscitation using hydroxyethyl starch (HES) 6% to a mean arterial blood...

journal_title：Anesthesia and analgesia

authors： Friedman Z,Berkenstadt H,Preisman S,Perel A

更新日期：2003-01-01 00:00:00

abstract：UNLABELLED:Recent investigations have sought to improve intrathecal analgesia by combining opioids with other classes of analgesics. In this study we assessed the ability of intrathecal midazolam to increase the potency and duration of the analgesic effects of intrathecal fentanyl without causing adverse effects. Thirt...

journal_title：Anesthesia and analgesia

authors： Tucker AP,Mezzatesta J,Nadeson R,Goodchild CS

更新日期：2004-06-01 00:00:00

abstract：:Total knee arthroplasty (TKA) may result in severe pain, and single-injection femoral nerve blocks (SFNB) have been demonstrated to have a limited duration of analgesia. Continuous femoral nerve blocks (CFNB) can prolong the analgesic duration of SFNB. We prospectively randomized 36 patients undergoing TKA to CFNB ver...

journal_title：Anesthesia and analgesia

authors： Salinas FV,Liu SS,Mulroy MF

更新日期：2006-04-01 00:00:00

abstract：UNLABELLED:Labor epidural analgesia (LEA) is allegedly associated with maternal fever and an increase in the newborn sepsis work-up (SWU) rate. In this study, we evaluated whether LEA causes an increase in the SWU rate compared with a Control group given parenteral narcotics for labor pain. Maternal and neonatal data w...

journal_title：Anesthesia and analgesia

authors： Kaul B,Vallejo M,Ramanathan S,Mandell G

更新日期：2001-10-01 00:00:00

abstract：:Multiple logistic regression studies frequently are performed with duration (e.g., operative time) included as an independent variable. We use narrative review of the statistical literature to highlight that when the association between duration and outcome is presumptively significant, the procedure itself (e.g., vid...

journal_title：Anesthesia and analgesia

authors： Dexter F,Dexter EU,Ledolter J

更新日期：2011-11-01 00:00:00

abstract：:We assessed the efficacy of patient-controlled analgesia (PCA) techniques for extended femoral nerve sheath block after total hip arthroplasty. Forty-five patients were divided into three groups of 15. Over 48 h, all patients received 0.125% bupivacaine with clonidine 1 microg/mL and sufentanil 0.1 microg/mL via a fem...

journal_title：Anesthesia and analgesia

authors： Singelyn FJ,Vanderelst PE,Gouverneur JM

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Hypotension after spinal anesthesia for cesarean delivery is common. Previous studies have demonstrated that a crystalloid fluid "coload" (rapid administration of a fluid bolus starting at the time of intrathecal injection) is superior to the conventional crystalloid preload (fluid administered before the in...

journal_title：Anesthesia and analgesia

authors： Siddik-Sayyid SM,Nasr VG,Taha SK,Zbeide RA,Shehade JM,Al Alami AA,Mokadem FH,Abdallah FW,Baraka AS,Aouad MT

更新日期：2009-10-01 00:00:00

abstract：:Hemodynamic responses to physostigmine were evaluated in eight patients with coma due to overdose with mainly anticholinergic drugs (AC) and in five patients with coma due to overdose with nonanticholinergic drugs (NAC). After correction of hypovolemia, but before administration of physostigmine, AC patients had signi...

journal_title：Anesthesia and analgesia

authors： Nilsson E,Meretoja OA,Neuvonen P

更新日期：1983-10-01 00:00:00

abstract：:The sedative effects of epidural anesthesia without volatile and IV anesthetics and quantification of the degree of epidural anesthesia-induced sedation have not been investigated. In the current study we evaluated the effects of epidural anesthesia on the bispectral index (BIS) during the awake phase and during gener...

journal_title：Anesthesia and analgesia

authors： Ishiyama T,Kashimoto S,Oguchi T,Yamaguchi T,Okuyama K,Kumazawa T

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Intrathecal drug delivery is an efficient method to administer therapeutic molecules to the central nervous system. However, even with identical drug dosage and administration mode, the extent of drug distribution in vivo is highly variable and difficult to control. Different cerebrospinal fluid (CSF) pulsat...

journal_title：Anesthesia and analgesia

authors： Hsu Y,Hettiarachchi HD,Zhu DC,Linninger AA

更新日期：2012-08-01 00:00:00

abstract：:Blind oral intubation using the Augustine Guide is helpful for intubating the trachea of patients presenting with difficult airways. This device has been modified by adding a fiberoptic scope with a built-in battery-powered light. We studied this Augustine Scope in 104 patients (Group AS) and compared the results with...

journal_title：Anesthesia and analgesia

authors： Krafft P,Krenn CG,Fitzgerald RD,Pernerstorfer T,Fridrich P,Weinstabl C

更新日期：1997-03-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to determine whether different levels of pain would respond similarly to analgesia. We compared the analgesic response to ibuprofen in subjects with moderate versus severe baseline pain in clinical trials using the third molar post-extraction dental pain model. We performed a po...

journal_title：Anesthesia and analgesia

authors： Averbuch M,Katzper M

更新日期：2003-07-01 00:00:00

abstract：UNLABELLED:Selective pulmonary vasodilation is an advantageous therapeutic strategy for cardiac surgical patients with increased pulmonary vascular resistance (PVR) and right ventricular failure. We hypothesized that milrinone, an adenosine-3',5'-cyclic monophosphate (cAMP)-selective phosphodiesterase enzyme (PDE) inhi...

journal_title：Anesthesia and analgesia

authors： Haraldsson s A,Kieler-Jensen N,Ricksten SE

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:The primary objective of this study was to compare the characteristics of culture-positive and culture-negative status in septic patients. We also determined whether culture status is associated with mortality and whether unique variables are associated with mortality in culture-positive and culture-negative...

journal_title：Anesthesia and analgesia

authors： Sigakis MJG,Jewell E,Maile MD,Cinti SK,Bateman BT,Engoren M

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:In 2001, the Center for Medicare and Medicaid Services issued a rule permitting states to "opt-out" of federal regulations requiring physician supervision of nurse anesthetists. We examined the extent to which this rule increased access to anesthesia care for urgent cases. METHODS:Using data from a national...

journal_title：Anesthesia and analgesia

authors： Sun E,Dexter F,Miller TR

更新日期：2016-06-01 00:00:00

abstract：UNLABELLED:We compared three ventilators-Servo 900C (Siemens Medical Systems, Danvers, MA), Aestiva 3000 (Datex-Ohmeda, Madison, WI), and NAD 6000 (North American Dräger, Telford, PA)-set to deliver pressure control ventilation using an infant test lung model. Ventilator settings were selected to test "near-maximum" se...

journal_title：Anesthesia and analgesia

authors： Stayer SA,Bent ST,Skjonsby BS,Frolov A,Andropoulos DB

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:N-methyl-D-aspartate receptor (NMDARs)-dependent central sensitization plays an important role in cancer pain. Binding of NMDAR subunit 2B (NR2B) by postsynaptic density protein-95 (PSD-95) can couple NMDAR activity to intracellular enzymes, such as neuronal nitric oxide synthase (nNOS), facilitate downstrea...

journal_title：Anesthesia and analgesia

authors： Liu Y,Cui X,Sun YE,Yang X,Ni K,Zhou Y,Ma Z,Gu X

更新日期：2014-06-01 00:00:00

abstract：UNLABELLED:Neuronal baseline K(+) channels were activated by several volatile anesthetics. Whole-cell recordings from cultured cerebellar granule neurons of 7-day-old male Sprague-Dawley rats showed outward-rectifying K(+) currents with a conductance of approximately 1.1 +/- 0.3 nS (n = 20) at positive potentials. The ...

journal_title：Anesthesia and analgesia

authors： Shin WJ,Winegar BD

更新日期：2003-05-01 00:00:00

abstract：UNLABELLED:Suppression of nitric oxide (NO) production alters the toxicity of cocaine and bupivacaine. We undertook this study to determine whether the systemic toxicity of two other local anesthetics that differ in antiarrhythmic activity, plasma clearance, and biotransformation are similarly affected by nitric oxide ...

journal_title：Anesthesia and analgesia

authors： Heavner JE,Shi B,Pitkänen M

更新日期：1999-04-01 00:00:00

abstract：:We evaluated risk of heart block after cardiopulmonary by-pass (CPB) in patients with normal conduction undergoing coronary artery bypass grafting who chronically received calcium-entry blockers, beta-blockers, or combined therapy. Before CPB, calcium-entry blockers alone produced an increase in P-R intervals but no c...

journal_title：Anesthesia and analgesia

authors： Henling CE,Slogoff S,Kodali SV,Arlund C

更新日期：1984-05-01 00:00:00

abstract：UNLABELLED:Genitofemoral neuritis, which occurs when the neurolytic solution spreads into the psoas muscle, is the most common complication after neurolytic lumbar sympathetic block. We developed a transdiscal approach for neurolytic lumbar sympathetic block to reduce the danger of genitofemoral neuritis by making a sy...

journal_title：Anesthesia and analgesia

authors： Ohno K,Oshita S

更新日期：1997-12-01 00:00:00

abstract：UNLABELLED:We determined the effects of fentanyl, sufentanil, morphine, and meperidine on the spontaneous contractility of isolated human pregnant uterine muscle strips. Uterine specimens were obtained from normal full-term parturients undergoing elective lower-segment cesarean delivery. Longitudinal muscle strips were...

journal_title：Anesthesia and analgesia

authors： Yoo KY,Lee J,Kim HS,Jeong SW

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Sedation protocols, including the use of sedation scales and regular sedation stops, help to reduce the length of mechanical ventilation and intensive care unit stay. Because clinical assessment of depth of sedation is labor-intensive, performed only intermittently, and interferes with sedation and sleep, pr...

journal_title：Anesthesia and analgesia

authors： Haenggi M,Ypparila-Wolters H,Buerki S,Schlauri R,Korhonen I,Takala J,Jakob SM

更新日期：2009-09-01 00:00:00