Statistical grand rounds: Importance of appropriately modeling procedure and duration in logistic regression studies of perioperative morbidity and mortality.

abstract：:Because no completely effective antiemetic exists for the prevention of postoperative nausea and vomiting (PONV), we hypothesize that a multimodal approach to management of PONV may reduce both vomiting and the need for rescue antiemetics in high-risk patients. After IRB approval, women undergoing outpatient laparosco...

journal_title：Anesthesia and analgesia

authors： Scuderi PE,James RL,Harris L,Mims GR 3rd

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Hypothermia (HT) reduces neuronal injury after perinatal asphyxia. The anesthetic gas xenon (XE) may enhance this effect. We investigated the sedative and respiratory effects of variable XE concentrations at 37 degrees C normothermia (NT) or 32 degrees C HT after a hypoxic-ischemic (HI) insult to determine t...

journal_title：Anesthesia and analgesia

authors： Dingley J,Hobbs C,Ferguson J,Stone J,Thoresen M

更新日期：2008-03-01 00:00:00

abstract：:The potency of conventional inhaled anesthetics increases with increasing age: the 50% effective dose (minimum alveolar anesthetic concentration [MAC]) for anesthesia in the neonatal animal or human exceeds MAC in the young adult by approximately 30% to 60%. We tested whether this relationship also applies to the alka...

journal_title：Anesthesia and analgesia

authors： Fang Z,Gong D,Ionescu P,Laster MJ,Eger EI 2nd,Kendig J

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:This study investigated the clinical performance of a model-based, patient-individualized closed-loop (CL) control system for propofol administration using the bispectral index (BIS) as a controlled variable during the induction and maintenance of anesthesia with propofol and remifentanil and studied the inf...

journal_title：Anesthesia and analgesia

authors： Neckebroek M,Boldingh JHL,De Smet T,Struys MMRF

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The blood/gas partition coefficient of a certain volatile anesthetic is of clinical importance because it determines its velocity of uptake into and elimination from the body of a patient and thus its pharmacokinetic behavior. To date, the blood/gas partition coefficients of isoflurane, sevoflurane, and desf...

journal_title：Anesthesia and analgesia

authors： Esper T,Wehner M,Meinecke CD,Rueffert H

更新日期：2015-01-01 00:00:00

abstract：:Combinations of alpha 2 agonists and opiates are used in the clinical management of pain to harness their potential synergistic interaction for analgesia while limiting their side-effects. To better predict the clinical consequences of this combination, we studied the behavioral effects of dexmedetomidine, a highly se...

journal_title：Anesthesia and analgesia

authors： Hayashi Y,Guo TZ,Maze M

更新日期：1996-09-01 00:00:00

abstract：:Hypotensive effects of the intravenous injection of adenine compounds [adenosine triphosphate (ATP), adenosine] were compared with those of sodium nitroprusside (SNP) in rabbits during light, stable halothane anesthesia. ATP and adenosine were almost equipotent in their effects on blood pressure and heart rate. The hy...

journal_title：Anesthesia and analgesia

authors： Fukunaga AF,Flacke WE,Bloor BC

更新日期：1982-03-01 00:00:00

abstract：:The choice between morphine and meperidine for postoperative pain is usually based on the preference of the prescriber, as few objective comparative data are available. This blind, randomized study compared the efficacy and side effects of morphine and meperidine administered by patient-controlled analgesia (PCA) for ...

journal_title：Anesthesia and analgesia

authors： Plummer JL,Owen H,Ilsley AH,Inglis S

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Asian American/Pacific Islanders (AAPIs) are the fastest-growing racial group in the United States. Despite a higher socioeconomic status, AAPI women experience higher rates of maternal morbidity and mortality. METHODS:Using the National Inpatient Sample, we performed a retrospective cohort analysis of wome...

journal_title：Anesthesia and analgesia

authors： Siddiqui M,Minhaj M,Mueller A,Tung A,Scavone B,Rana S,Shahul S

更新日期：2017-03-01 00:00:00

abstract：:Spine surgery has been growing rapidly as a neurosurgical operation, with an increase of 220% over a 15-year period. Intraoperative blood transfusion is a major outcome determinant of spine procedures. Various approaches, including pharmacologic and nonpharmacologic therapies, have been tested to decrease both intraop...

journal_title：Anesthesia and analgesia

authors： Willner D,Spennati V,Stohl S,Tosti G,Aloisio S,Bilotta F

更新日期：2016-11-01 00:00:00

abstract：:A 91-yr-old man (57 kg, 156 cm, ASA III) received an infraclavicular brachial plexus block for surgery of bursitis of the olecranon. Twenty minutes after infraclavicular injection of 30 mL of mepivacaine 1% (Scandicain) and 5 min after supplementation of 10 mL of prilocaine 1% (Xylonest) using an axillary approach, th...

journal_title：Anesthesia and analgesia

authors： Litz RJ,Roessel T,Heller AR,Stehr SN

更新日期：2008-05-01 00:00:00

abstract：:The hemodynamic effects of high-dose hydromorphone hydrochloride (H), 1.25 mg/kg, were investigated in 10 patients with normal ventricular function undergoing coronary artery bypass graft (CABG) surgery. One patient with unstable angina was excluded from the study because of hypotension and facial flushing after a 6-m...

journal_title：Anesthesia and analgesia

authors： Welti RS,Moldenhauer CC,Hug CC Jr,Kaplan JA,Holbrook GW

更新日期：1984-01-01 00:00:00

abstract：:There are quantitative deficiencies in the coagulation system for at least the first 6 mo of life. Clinical experience, however, does not indicate an increased risk of excessive bleeding during surgical procedures. Thrombelastography, a test providing a functional evaluation of coagulation, was used to assess the hemo...

journal_title：Anesthesia and analgesia

authors： Miller BE,Bailey JM,Mancuso TJ,Weinstein MS,Holbrook GW,Silvey EM,Tosone SR,Levy JH

更新日期：1997-04-01 00:00:00

abstract：:Effective communication is essential in today's health care environment, and poor communication can lead to conflict among health care providers. Differences in cultures and beliefs can further incite conflict among health care team members, families, and patients. Pediatric patient care has a higher potential for con...

journal_title：Anesthesia and analgesia

authors： Sinskey JL,Chang JM,Shibata GS,Infosino AJ,Rouine-Rapp K

更新日期：2019-10-01 00:00:00

abstract：:Evaluation of a new inhaled anesthetic requires determination of the anesthetic's potential to predispose to ventricular (and other) arrhythmias in an animal model. This need poses logistic and economic burdens if the effects of large numbers of new anesthetics are to be surveyed. We have devised a technique for deter...

journal_title：Anesthesia and analgesia

authors： Laster MJ,Johnson BH,Eger EI 2nd,Taheri S

更新日期：1990-06-01 00:00:00

abstract：:Early tracheal extubation has been safely performed after large operative procedures, questioning the need for routine postoperative ventilation. Because immediate postoperative tracheal extubation of liver transplantation patients has not been previously reported, we performed preliminary studies at two institutions ...

journal_title：Anesthesia and analgesia

authors： Mandell MS,Lockrem J,Kelley SD

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Hypotension compromises local tissue perfusion, thereby reducing tissue oxygenation. Hypotension might thus be expected to promote infection. Hypotension on surgical wards, while usually less severe than intraoperative hypotension, is common and often prolonged. In this retrospective cohort study, we tested ...

journal_title：Anesthesia and analgesia

authors： Yilmaz HO,Babazade R,Leung S,Zimmerman NM,Makarova N,Saasouh W,Stocchi L,Gorgun E,Sessler DI,Turan A

更新日期：2018-11-01 00:00:00

abstract：:This study was performed to compare the efficacy of tropisetron, droperidol, and saline in the prevention of postoperative nausea and vomiting (PONV) and to compare the possible adverse effects of these drugs in gynecologic incontinence surgery. Using a randomized, double-blind study design, we studied 150 women under...

journal_title：Anesthesia and analgesia

authors： Purhonen S,Kauko M,Koski EM,Nuutinen L

更新日期：1997-03-01 00:00:00

abstract：:We assessed the effect of small clonidine doses on anxiolysis, analgesia, and hemodynamic stability in patients undergoing abdominal hysterectomy. A total of 61 patients, ASA status I-II, were randomly assigned to receive either oral clonidine 100 microg (n = 29) or placebo (n = 32) before surgery and 24 h after surge...

journal_title：Anesthesia and analgesia

authors： Hidalgo MP,Auzani JA,Rumpel LC,Moreira NL Jr,Cursino AW,Caumo W

更新日期：2005-03-01 00:00:00

abstract：:In this prospective randomized, double-blind study, we investigated the effect of ondansetron on the lidocaine subarachnoid block. Fifty-four male patients scheduled for transurethral surgery under subarachnoid anesthesia received oral ondansetron 4 mg the evening before surgery and 4 mg IV 15 min before subarachnoid ...

journal_title：Anesthesia and analgesia

authors： Fassoulaki A,Melemeni A,Zotou M,Sarantopoulos C

更新日期：2005-06-01 00:00:00

abstract：:We investigated the effects of a close carotid injection of vecuronium on changes in phrenic nerve activity during different states of oxygenation. Experiments were performed on normothermic and mechanically ventilated adult New Zealand White rabbits with a tracheostomy under continuous thiopental infusion. Carotid ar...

journal_title：Anesthesia and analgesia

authors： Wyon N,Eriksson LI,Yamamoto Y,Lindahl SG

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:There are profound racial and ethnic disparities in obstetric outcomes in the United States, but little is known about disparities in risk of postpartum hemorrhage (PPH). We explored the association of race and ethnicity on the risk of PPH due to uterine atony with sequential adjustment for possible mediatin...

journal_title：Anesthesia and analgesia

authors： Bryant A,Mhyre JM,Leffert LR,Hoban RA,Yakoob MY,Bateman BT

更新日期：2012-11-01 00:00:00

abstract：:Dilation of lymphatic vessels may contribute to iatrogenic dissemination of cancer cells during surgery. We sought to determine whether neuraxial anesthesia reduces regional lymphatic flow. Using nuclear lymphoscintigraphy, 5 participants receiving spinal anesthesia for brachytherapy had lower extremity lymph flow at ...

journal_title：Anesthesia and analgesia

authors： Hiller JG,Ismail HM,Hofman MS,Narayan K,Ramdave S,Riedel BJ

更新日期：2016-11-01 00:00:00

abstract：UNLABELLED:Pain complicates the recovery process after ambulatory surgery. We surveyed 175 ambulatory surgery patients to determine pain severity, analgesic use, relationship of pain to duration of recovery, and the relative importance of various factors to predicting these outcomes. Multivariate regression analysis wa...

journal_title：Anesthesia and analgesia

authors： Pavlin DJ,Chen C,Penaloza DA,Polissar NL,Buckley FP

更新日期：2002-09-01 00:00:00

abstract：UNLABELLED:Forty-eight healthy parturients scheduled for elective cesarean delivery were randomly allocated to receive intrathecally either 12 mg of hyperbaric bupivacaine plus 12.5 microg of fentanyl (n = 23) or bupivacaine alone (n = 25). In the latter group, IV 12.5 microg of fentanyl was administered immediately af...

journal_title：Anesthesia and analgesia

authors： Siddik-Sayyid SM,Aouad MT,Jalbout MI,Zalaket MI,Berzina CE,Baraka AS

更新日期：2002-07-01 00:00:00

abstract：UNLABELLED:The availability of an analgesic compound devoid of the side effects associated with the commonly used opioid and nonsteroidal antiinflammatory drugs would be useful during the perioperative period. Although adenosine has analgesic and anesthetic-sparing properties, it also produces dose-dependent cardiovasc...

journal_title：Anesthesia and analgesia

authors： Wang B,Tang J,White PF,Foster AC,Grettenberger HM,Kopcho J,Wender RH

更新日期：1997-09-01 00:00:00

abstract：:Lumbar cerebrospinal fluid levels of 5-hydroxyindoleacetic acid, which are used as indicators of central nervous system serotonergic neuronal activity, were significantly higher in 67 patients with chronic pain and in 32 patients with acute pain (23.6 +/- 3.3 and 23.1 +/- 3.8, respectively) than in 30 patients (8.8 +/...

journal_title：Anesthesia and analgesia

authors： Ghia JN,Mueller RA,Duncan GH,Scott DS,Mao W

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Women laboring with epidural analgesia experience fever much more frequently than do women who chose other forms of analgesia, and maternal intrapartum fever is associated with numerous adverse consequences, including brain injury in the fetus. We developed a model of noninfectious inflammatory fever in the ...

journal_title：Anesthesia and analgesia

authors： Segal S,Pancaro C,Bonney I,Marchand JE

更新日期：2017-12-01 00:00:00

abstract：:We determined the effects of hyperkalemia, hypernatremia, hyperosmolality and hypo-osmolality on halothane requirement (MAC) in dogs. Hyperkalemia did not change cerebrospinal fluid potassium or MAC. Hypernatremia proportionately increased cerebrospinal fluid sodium and osmolality. MAC concomitantly increased 43%. Ser...

journal_title：Anesthesia and analgesia

authors： Tanifuji Y,Eger EI 2nd

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:Cardiac surgery for carcinoid heart disease is complicated by hemodynamic instability secondary to carcinoid crises, cardiovascular dysfunction, and blood loss. The safety of vasopressors and the benefit of aprotinin during concomitant octreotide administration are uncertain. METHODS:We reviewed the effects...

journal_title：Anesthesia and analgesia

authors： Weingarten TN,Abel MD,Connolly HM,Schroeder DR,Schaff HV

更新日期：2007-11-01 00:00:00