Xenon/hypothermia neuroprotection regimes in spontaneously breathing neonatal rats after hypoxic-ischemic insult: the respiratory and sedative effects.

abstract：:We evaluated empirically the extent to which the use of a cognitive aid during a high-fidelity simulation of a malignant hyperthermia (MH) event facilitated the correct and prompt treatment of MH. We reviewed the management of 48 simulated adult MH scenarios; 24 involving CA 1 and 24 involving CA 2 residents. In the C...

journal_title：Anesthesia and analgesia

authors： Harrison TK,Manser T,Howard SK,Gaba DM

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Even though current perception threshold (CPT) has been used for evaluating the effectiveness of sensory block in patients before surgery, its reliability under controlled conditions has not been investigated. Two independent investigations were performed. The primary objective of the first study was to dete...

journal_title：Anesthesia and analgesia

authors： Gaudreault F,Drolet P,Fallaha M,Varin F

更新日期：2015-03-01 00:00:00

abstract：:Although the use of fine-gauge spinal needles reduces the incidence of postdural puncture headache, they are associated with increased risk of placement failure as a result of deflection and bending. This in vitro study quantifies spinal needle deflection from the axis of insertion with respect to needle type, gauge, ...

journal_title：Anesthesia and analgesia

authors： Sitzman BT,Uncles DR

更新日期：1996-02-01 00:00:00

abstract：:The brain is one of the most metabolically active organs in the body. The brain's high energy demand associated with wakefulness persists during rapid eye movement sleep, and even during non-rapid eye movement sleep, cerebral oxygen consumption is only reduced by 20%. The active bioenergetic state parallels metabolic ...

journal_title：Anesthesia and analgesia

authors： Benveniste H,Heerdt PM,Fontes M,Rothman DL,Volkow ND

更新日期：2019-04-01 00:00:00

abstract：:We measured the pharmacokinetics of hydromorphone in normal volunteers given three doses of the drug (10, 20, and 40 micrograms/kg) as intravenous 45-s injections on different days. Concentrations of hydromorphone in plasma from serial blood samples were measured by a high-performance liquid chromatography method spec...

journal_title：Anesthesia and analgesia

authors： Hill HF,Coda BA,Tanaka A,Schaffer R

更新日期：1991-03-01 00:00:00

abstract：:Three types of catheters, the Arrow multi-orifice catheter, the American Edwards 7 Fr Swan-Ganz catheter and the Cook Bunegin-Albin multi-orifice CVP catheter were evaluated for their ability to retrieve venous air emboli and effect on the success rate of resuscitation from venous air emboli. The catheters were insert...

journal_title：Anesthesia and analgesia

authors： Colley PS,Artru AA

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Spinal cord monitoring is associated with a significantly lower rate of neurologic deficits after deformity surgery, and has been shown to have predictive value in cervical, thoracic, and lumbar surgery. Lower extremity motor evoked potentials (MEPs) are particularly sensitive to anesthetics and physiologic ...

journal_title：Anesthesia and analgesia

authors： Deiner SG,Kwatra SG,Lin HM,Weisz DJ

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The clinical utility of focused transthoracic echocardiography (TTE) is increasingly recognized in perioperative medicine. However its use is limited among anesthesiologists because of a lack of training. The most efficient training methods have not been determined. We hypothesized that simulation-based TTE ...

journal_title：Anesthesia and analgesia

authors： Neelankavil J,Howard-Quijano K,Hsieh TC,Ramsingh D,Scovotti JC,Chua JH,Ho JK,Mahajan A

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:While transfusion-related acute lung injury (TRALI) remains the primary cause of transfusion-related fatalities (37%), recent reports estimate the incidence of TRALI at 0.008% per unit of plasma transfused and 0.004% per all products transfused. Because blood banks have moved toward male-predominant plasma, ...

journal_title：Anesthesia and analgesia

authors： Meyer DE,Reynolds JW,Hobbs R,Bai Y,Hartwell B,Pommerening MJ,Fox EE,Wade CE,Holcomb JB,Cotton BA

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:As orexinergic (OXergic) neurons have been reported to mediate emotional changes, benzodiazepines might interact with OXergic neurons. METHODS:We examined the interactions between OXergic neurons and benzodiazepine receptors in orexin-A (100 nM) and K+ (25 mM)-evoked norepinephrine release from rat cerebroc...

journal_title：Anesthesia and analgesia

authors： He Y,Kudo M,Kudo T,Kushikata T,Li E,Hirota K

更新日期：2007-02-01 00:00:00

abstract：:Morphine anesthesia is often recommended in patients with reduced cardiac reserve. As the effect of morphine on the balance between myocardial oxygen supply and demand is not well understood, the effect of large doses of morphine (3 mg/kg, subcutaneously) on experimental myocardial infarction size in the rat was evalu...

journal_title：Anesthesia and analgesia

authors： Markiewicz W,Finberg JP,Lichtig C

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Twenty percent of patients born with congenital heart disease present with right ventricular outflow tract abnormalities. These patients require multiple surgical procedures in their lifetime. Transcatheter pulmonary valve replacement (TPVR) has become a viable alternative to conventional pulmonary valve and...

journal_title：Anesthesia and analgesia

authors： Arboleda Salazar R,Heggie J,Wolski P,Horlick E,Osten M,Meineri M

更新日期：2018-07-01 00:00:00

abstract：:It is not known how sevoflurane affects the cardiac conduction system. We compared the effects of halothane, isoflurance, and sevoflurane on specialized atrioventricular (AV) conduction times in eight pentobarbital-anesthetized dogs. AV conduction times with three inhaled anesthetics at end-tidal concentrations of 1 a...

journal_title：Anesthesia and analgesia

authors： Nakaigawa Y,Akazawa S,Shimizu R,Ishii R,Yamato R

更新日期：1995-08-01 00:00:00

abstract：:Electroconvulsive therapy (ECT) is a highly effective treatment for severe depression. However, its use is associated with significant posttreatment cognitive impairment. Magnetic seizure therapy (MST) was developed as an alternative therapy that could reduce postseizure side effects through the induction of more "foc...

journal_title：Anesthesia and analgesia

authors： White PF,Amos Q,Zhang Y,Stool L,Husain MM,Thornton L,Downing M,McClintock S,Lisanby SH

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Animal models show us that specific activation of the p38 mitogen-activated protein kinase (MAPK) may be a pivotal step in lidocaine neurotoxicity, but this has not been investigated in the case of two very widely used local anesthetics, bupivacaine and ropivacaine. We investigated the hypotheses that these ...

journal_title：Anesthesia and analgesia

authors： Lirk P,Haller I,Colvin HP,Lang L,Tomaselli B,Klimaschewski L,Gerner P

更新日期：2008-05-01 00:00:00

abstract：:Over the last decade, there has been a heightened awareness and an increase in the amount of literature being published on recognition and prediction of the difficult airway. During the preoperative evaluation of the airway, a thorough history and physical specifically related to the airway should be performed. Variou...

journal_title：Anesthesia and analgesia

authors： Cattano D,Panicucci E,Paolicchi A,Forfori F,Giunta F,Hagberg C

更新日期：2004-12-01 00:00:00

abstract：:The hemodynamic effects of high-dose hydromorphone hydrochloride (H), 1.25 mg/kg, were investigated in 10 patients with normal ventricular function undergoing coronary artery bypass graft (CABG) surgery. One patient with unstable angina was excluded from the study because of hypotension and facial flushing after a 6-m...

journal_title：Anesthesia and analgesia

authors： Welti RS,Moldenhauer CC,Hug CC Jr,Kaplan JA,Holbrook GW

更新日期：1984-01-01 00:00:00

abstract：:We investigated the effects of halothane on changes in cardiac function during hypoperfusion and recovery of function after reperfusion in the isolated perfused guinea pig heart. Heart rate, atrioventricular (AV) conduction time, the incidence and severity of dysrhythmias, and isovolumetric left ventricular systolic p...

journal_title：Anesthesia and analgesia

authors： Buljubasic N,Marijic J,Stowe DF,Kampine JP,Bosnjak ZJ

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle calcium regulation associated primarily, but not exclusively, with mutations in the skeletal muscle ryanodine receptor. Associated environmental factors, however, may also be important for expression of the syndrome. METHODS AND RE...

journal_title：Anesthesia and analgesia

authors： Capacchione JF,Radimer MC,Sagel JS,Kraus GP,Sambuughin N,Muldoon SM

更新日期：2009-03-01 00:00:00

abstract：IMPLICATIONS:We measured plasma propofol levels by head space-gas chromatography analysis using solid-phase microextraction. This method saves time, and does not require elimination of interfering substances in the plasma. The coefficient variation was +/-5% to +/-30%. The detection limit was 10 ng/mL. ...

journal_title：Anesthesia and analgesia

authors： Fujita A,Higuchi J,Nagai T,Tokudome S,Sakio H

更新日期：2000-06-01 00:00:00

abstract：:A guinea pig model of halothane hepatitis was used to explore the humoral immune response induced by multiple halothane exposures and the potential role this response might play in contributing to liver damage. Three different strains of guinea pigs (Strain 2, Amana, and Hartley) were exposed to 1% halothane under eit...

journal_title：Anesthesia and analgesia

authors： Siadat-Pajouh M,Hubbard AK,Roth TP,Gandolfi AJ

更新日期：1987-12-01 00:00:00

abstract：:In a prospective, randomized, double-blind study, we investigated whether epinephrine increased the efficacy of levobupivacaine and sufentanil during epidural labor analgesia. Seventy term parturients received an epidural injection of levobupivacaine 0.125% and sufentanil 0.75 microg/mL with or without 1:800,000 epine...

journal_title：Anesthesia and analgesia

authors： Soetens FM,Soetens MA,Vercauteren MP

更新日期：2006-07-01 00:00:00

abstract：:The efficacy and safety of 0.5% hyperbaric bupivacaine (Sensorcaine, Astra) was evaluated in 22 patients undergoing elective cesarean section under spinal anesthesia. The dose varied from 7.5 to 10 mg, (depending on the patient's height) which was significantly lower than previously reported. Patients were placed in h...

journal_title：Anesthesia and analgesia

authors： Santos A,Pedersen H,Finster M,Edström H

更新日期：1984-11-01 00:00:00

abstract：:Seven anesthetized patients were studied to determine the interaction between pancuronium and lincomycin and the ability of neostigmine and 4-aminopyridine to antagonize the block. Lincomycin 600 mg given IV alone did not decrease twitch tension. An 8 to 10% decrease in twitch tension occurred when lincomycin was give...

journal_title：Anesthesia and analgesia

authors： Booij LH,Miller RD,Crul JF

更新日期：1978-05-01 00:00:00

abstract：:The nasal route is preferred for fiberoptic intubation. Placing a lubricated endotracheal tube through the nostril can guide the fiberoptic scope towards the larynx. It would be helpful for optimal visualization of the vocal cord when the scope is passed through the endotracheal tube if the length of nares-vocal cord ...

journal_title：Anesthesia and analgesia

authors： Han DW,Shim YH,Shin CS,Lee YW,Lee JS,Ahn SW

更新日期：2005-05-01 00:00:00

abstract：:Invasive cardiac output (CO) monitoring, traditionally performed with transpulmonary thermodilution techniques, is usually reserved for high-risk patients because of the inherent risks of these methods. In contrast, transesophageal Doppler (TED) technology offers a safe, quick, and less invasive method for routine mea...

journal_title：Anesthesia and analgesia

authors： Schober P,Loer SA,Schwarte LA

更新日期：2009-08-01 00:00:00

abstract：:The performance of five of the most commonly used halothane vaporizers and three enflurane vaporizers was tested under conditions encountered in low-flow and closed-circuit anesthesia. Anesthetic gas concentrations were measured continuously with a mass spectrometer connected to a circle system. The results indicated ...

journal_title：Anesthesia and analgesia

authors： Lin CY

更新日期：1980-05-01 00:00:00

abstract：:The number of anesthesiology residents pursuing critical care medicine (CCM) fellowship training has been decreasing in recent years. A significant number of training positions remain unfilled each year. Possible causes of this decline were evaluated by surveying residents regarding their attitudes toward practice and...

journal_title：Anesthesia and analgesia

authors： Durbin CG Jr,McLafferty CL Jr

更新日期：1993-09-01 00:00:00

abstract：UNLABELLED:We investigated the effect of lidocaine on the incidence of cognitive dysfunction in the early postoperative period after cardiac surgery. One-hundred-eighteen patients undergoing elective coronary artery bypass surgery with cardiopulmonary bypass (CPB) were randomized to receive either lidocaine (1.5 mg/kg ...

journal_title：Anesthesia and analgesia

authors： Wang D,Wu X,Li J,Xiao F,Liu X,Meng M

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Whether intraoperative analgesics have an impact on postoperative cancer recurrence is unknown. Some investigations suggest that the opioids could favor relapse and that regional analgesia and nonsteroidal antiinflammatory drugs could improve cancer prognosis. We retrospectively reviewed our series of breast...

journal_title：Anesthesia and analgesia

authors： Forget P,Vandenhende J,Berliere M,Machiels JP,Nussbaum B,Legrand C,De Kock M

更新日期：2010-06-01 00:00:00