Assessment of vaporizer performance in low-flow and closed-circuit anesthesia.

abstract：:General anesthesia results in increases in respiratory elastance and flow resistance within 10-15 min after induction. Stabilization (compensation) of the respiratory system in the face of this added load is related to the addition of active (contractile) force-length and force-velocity properties to its internal impe...

journal_title：Anesthesia and analgesia

authors： Baydur A,Sassoon CS,Stiles CM

更新日期：1986-01-01 00:00:00

abstract：:The effects of induction of anesthesia with diazepam and midazolam on baroreflex control of heart rate and on plasma levels of catecholamines were investigated in this study. Group 1 subjects (n = 10) received diazepam, 0.4 mg/kg. Group 2 subjects (n = 10) received midazolam, 0.3 mg/kg. Baroreflex function was assesse...

journal_title：Anesthesia and analgesia

authors： Marty J,Gauzit R,Lefevre P,Couderc E,Farinotti R,Henzel C,Desmonts JM

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:The switch from International Classification of Diseases, Ninth Revision, Clinical Modification to International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) for coding of inpatient procedures in the United States increased the number of procedural codes more than 19-fold,...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,O'Neill L

更新日期：2019-06-01 00:00:00

abstract：:The effect of release of intraoperative thigh tourniquets on velocity of blood flow in the middle cerebral artery was examined in five patients given general anesthesia with controlled ventilation for lower extremity orthopedic procedures using transcranial Doppler sonography. Middle cerebral artery blood flow velocit...

journal_title：Anesthesia and analgesia

authors： Hirst RP,Slee TA,Lam AM

更新日期：1990-11-01 00:00:00

abstract：:In a porcine model of uncontrolled hemorrhagic shock, we evaluated the effects of fluid resuscitation versus arginine vasopressin (AVP) combined with hypertonic-hyperoncotic hydroxyethyl starch solution (HHS) on cerebral perfusion pressure (CPP) and on cerebral metabolism using intracerebral microdialysis. Sixteen ane...

journal_title：Anesthesia and analgesia

authors： Meybohm P,Cavus E,Bein B,Steinfath M,Brand PA,Scholz J,Dörges V

更新日期：2006-10-01 00:00:00

abstract：:Quantitative Sensory Testing (QST) is a psycho-physiological test used to identify dysfunction of individual nerve fiber types. In the present study, we investigated whether selective nerve fiber dysfunction, as assessed by QST, correlates with the effectiveness of epidural steroid injections (ESI) in patients with lu...

journal_title：Anesthesia and analgesia

authors： Schiff E,Eisenberg E

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Ten to fifteen percent of awake patients develop neurological deficits secondary to cerebral hypoperfusion after carotid artery cross-clamping. The reversal of such deficits by increasing the inspired oxygen fraction (Fio(2)) has been demonstrated, and regional cerebral oxygenation (rSO(2)) has been shown to...

journal_title：Anesthesia and analgesia

authors： Picton P,Chambers J,Shanks A,Dorje P

更新日期：2010-02-01 00:00:00

abstract：:Lidocaine and MgSO4 are often coadministered to patients with pregnancy-induced hypertension. This study examined whether MgSO4 alters the lidocaine-seizure threshold in the rat and, if so, whether systemic MgSO4 administration is as effective as intracerebroventricular MgSO4 infusion. In Experiment 1, rats were admin...

journal_title：Anesthesia and analgesia

authors： Kim YJ,McFarlane C,Warner DS,Baker MT,Choi WW,Dexter F

更新日期：1996-12-01 00:00:00

abstract：:Patients with frailty experience substantial physical and emotional distress related to their condition and face increased morbidity and mortality compared with their nonfrail peers. Palliative care is an interdisciplinary medical specialty focused on improving quality of life for patients with serious illness, includ...

journal_title：Anesthesia and analgesia

authors： Crooms RC,Gelfman LP

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Pathophysiologic changes in children with congenital heart disease may alter the effect of drugs by influencing the pharmacokinetics (PK). Considering the limited literature that describes the PK of etomidate in pediatric patients, especially in those with tetralogy of Fallot (TOF), our aim was to characteri...

journal_title：Anesthesia and analgesia

authors： Shen Y,Cai MH,Ji W,Bai J,Huang Y,Sun Y,Lin L,Niu J,Zhang MZ

更新日期：2016-09-01 00:00:00

abstract：:Morphine given intracerebroventricularly releases spinal dynorphin A (Dyn) in mice. The present study was undertaken to determine whether morphine given intrathecally (IT) released Dyn. We demonstrated that the antinociceptive action of morphine was enhanced by procedures that are known to attenuate Dyn action. First,...

journal_title：Anesthesia and analgesia

authors： Holmes BB,Fujimoto JM

更新日期：1993-12-01 00:00:00

abstract：:The Meyer-Overton hypothesis predicts that anesthetic potency correlates inversely with lipophilicity; e.g., MAC times the olive oil/gas partition coefficient equals a constant of approximately 1.82 +/- 0.56 atm (mean +/- sd) for conventional inhaled anesthetics. MAC is the minimum alveolar concentration of anesthetic...

journal_title：Anesthesia and analgesia

authors： Won A,Oh I,Liao M,Sonner JM,Harris RA,Laster MJ,Brosnan R,Trudell JR,Eger EI 2nd

更新日期：2006-05-01 00:00:00

abstract：:The anesthetic effect of lidocaine was evaluated in rats by determining the change in anesthetic requirement of cyclopropane MAC that was produced by blood concentrations of lidocaine in the clinically useful range. A linear reduction in anesthetic requirement was produced with concentrations up to 1 mug/ml. Further i...

journal_title：Anesthesia and analgesia

authors： DiFazio CA,Neiderlehner JR,Burney RG

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Statins have been shown to possess antiinflammatory and immunomodulatory effects. In this study, we sought to determine if preoperative statin therapy is associated with a reduced frequency of postoperative acute respiratory distress syndrome (ARDS) in surgical populations at increased risk of developing ARD...

journal_title：Anesthesia and analgesia

authors： Yadav H,Lingineni RK,Slivinski EJ,Stockler KA,Subramanian A,Oderich GS,Wigle DA,Carter RE,Kor DJ

更新日期：2014-10-01 00:00:00

abstract：:Changes in cardiac output in response to augmenting cardiac contractility, preload, and heart rate during enflurane anesthesia were examined in 12 open-chested dogs. Cardiac contractility was assessed by the slope of the end-systolic pressure-volume relation (Emax). Dobutamine (3, 6, and 9 micrograms.kg-1.min-1) was a...

journal_title：Anesthesia and analgesia

authors： Sato M,Hoka S,Arimura H,Ono K,Yoshitake J

更新日期：1991-11-01 00:00:00

abstract：UNLABELLED:Economic considerations suggest that it is desirable to keep operating rooms fully used when staffed, but the optimum utilization of an operating room (OR) is not known. We created a simulation of an OR to define optimum utilization. We set operational goals of having cases start within 15 min of the schedul...

journal_title：Anesthesia and analgesia

authors： Tyler DC,Pasquariello CA,Chen CH

更新日期：2003-04-01 00:00:00

abstract：UNLABELLED:Small-dose ketamine in combination with sedative drugs has increasingly been used for sedation and analgesia in local anesthesia. We compared the clinical efficacy of midazolam with two different ketamine infusion regimens during plastic surgery under local anesthesia. Sixty patients undergoing plastic surge...

journal_title：Anesthesia and analgesia

authors： Deng XM,Xiao WJ,Luo MP,Tang GZ,Xu KL

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Isoflurane activates vascular adenosine triphosphate sensitive potassium (K(ATP)) channels, and may induce vasodilation. In the present study, we investigated whether hyperglycemia modifies isoflurane activation of vascular K(ATP) channel. METHODS:We used a cell-attached patch-clamp configuration to test th...

journal_title：Anesthesia and analgesia

authors： Kawano T,Tanaka K,Mawatari K,Oshita S,Takahashi A,Nakaya Y

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:There is a considerable discrepancy between the reported incidences of awareness under anesthesia in children (0.2%-2.7%). In this prospective, observational, cohort study we evaluated 1) the incidence of awareness during general anesthesia in children across three settings, 2) factors contributing to awaren...

journal_title：Anesthesia and analgesia

authors： Malviya S,Galinkin JL,Bannister CF,Burke C,Zuk J,Popenhagen M,Brown S,Voepel-Lewis T

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:While US Food and Drug Administration (FDA) black box warnings are common, their impact on perioperative outcomes is unclear. Hydroxyethyl starch (HES) is associated with increased bleeding and kidney injury in patients with sepsis, leading to an FDA black box warning in 2013. Among patients undergoing muscu...

journal_title：Anesthesia and analgesia

authors： Krishnamoorthy V,Ellis AR,McLean DJ,Stefan MS,Nathanson BH,Cobert J,Lindenauer PK,Brookhart MA,Ohnuma T,Raghunathan K

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Cannabinoid agonists induce norepinephrine release in central, spinal, and peripheral sites. Previous studies suggest an interaction between the cannabinoid and adrenergic systems on antinociception. In this study, we sought to verify whether the CB1 and CB2 cannabinoid receptor agonists anandamide and N-pal...

journal_title：Anesthesia and analgesia

authors： Romero TR,Resende LC,Guzzo LS,Duarte ID

更新日期：2013-02-01 00:00:00

abstract：:Clonidine in spinal and epidural blocks prolongs anesthesia, but can cause hypotension and bradycardia. The aim of our study was to compare hemodynamic and analgesic effects of spinal versus epidural clonidine alone and after repetitive dosing. In a prospective, randomized, double-blind study, we evaluated 40 patients...

journal_title：Anesthesia and analgesia

authors： Klimscha W,Chiari A,Krafft P,Plattner O,Taslimi R,Mayer N,Weinstabl C,Schneider B,Zimpfer M

更新日期：1995-02-01 00:00:00

abstract：UNLABELLED:We compared the efficacy of gas exchange during supraglottic combined-frequency jet ventilation via a jet ventilation laryngoscope and during monofrequent jet ventilation via the Mon-Jet catheter (Xomed, Jacksonville, FL). Twenty-three anesthetized (propofol, fentanyl, vecuronium) patients undergoing microla...

journal_title：Anesthesia and analgesia

authors： Bacher A,Pichler K,Aloy A

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Neuropathic pain is a result of a primary lesion or dysfunction of the peripheral or central nervous system, and its treatment is challenging. Animal models have been helpful in understanding mechanisms of neuropathic pain and in developing new treatment strategies. In this study, we examined the effect of p...

journal_title：Anesthesia and analgesia

authors： Ozsoylar O,Akçali D,Cizmeci P,Babacan A,Cahana A,Bolay H

更新日期：2008-10-01 00:00:00

abstract：UNLABELLED:To evaluate the possible effects of outpatient preoperative evaluation (OPE) for new surgical patients who will be inpatients, we conducted an observational study at a university hospital in The Netherlands. Various outcomes before and after the introduction of an OPE clinic were compared. The study populati...

journal_title：Anesthesia and analgesia

authors： van Klei WA,Moons KG,Rutten CL,Schuurhuis A,Knape JT,Kalkman CJ,Grobbee DE

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether mechanically ventilated trauma patients with a positive urine drug screen (UDS) for cocaine and/or amphetamines have different opioid analgesic and sedative requirements compared with similar patients with a negative drug screen for these stimulants. METHOD...

journal_title：Anesthesia and analgesia

authors： Kram B,Kram SJ,Sharpe ML,James ML,Kuchibhatla M,Shapiro ML

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:As orexinergic (OXergic) neurons have been reported to mediate emotional changes, benzodiazepines might interact with OXergic neurons. METHODS:We examined the interactions between OXergic neurons and benzodiazepine receptors in orexin-A (100 nM) and K+ (25 mM)-evoked norepinephrine release from rat cerebroc...

journal_title：Anesthesia and analgesia

authors： He Y,Kudo M,Kudo T,Kushikata T,Li E,Hirota K

更新日期：2007-02-01 00:00:00

abstract：:The influence of preoxygenation in the supine (n = 10) versus the 45 degrees head-up (n = 10) position on the duration of apnea leading to a decrease in arterial oxygen saturation to 95%, as monitored by pulse oximetry, was investigated in 20 women undergoing elective cesarean section at term of pregnancy. The results...

journal_title：Anesthesia and analgesia

authors： Baraka AS,Hanna MT,Jabbour SI,Nawfal MF,Sibai AA,Yazbeck VG,Khoury NI,Karam KS

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Even though current perception threshold (CPT) has been used for evaluating the effectiveness of sensory block in patients before surgery, its reliability under controlled conditions has not been investigated. Two independent investigations were performed. The primary objective of the first study was to dete...

journal_title：Anesthesia and analgesia

authors： Gaudreault F,Drolet P,Fallaha M,Varin F

更新日期：2015-03-01 00:00:00

abstract：:During Gram-negative sepsis, endotoxin lipopolysaccharide (LPS) may activate host inflammatory responses, resulting in the systemic inflammatory response syndrome and the adult respiratory distress syndrome. In cell culture systems, LPS activation of cellular responses may be potentiated by plasma proteins. In the iso...

journal_title：Anesthesia and analgesia

authors： Goldsmith JA,Kavanagh BP,Pearl RG

更新日期：1996-08-01 00:00:00