A simple method for detecting plasma propofol.

abstract：:The relative safety of epidural catheter placement with subsequent heparinization has been well documented. However, what is the risk of neurologic sequelae in such patients who receive warfarin perioperatively? This study retrospectively evaluates the risk of spinal hematoma in patients receiving postoperative epidur...

journal_title：Anesthesia and analgesia

authors： Horlocker TT,Wedel DJ,Schlichting JL

更新日期：1994-07-01 00:00:00

abstract：:The effect of age (over 70 yr) on the pharmacokinetics and pharmacodynamics of edrophonium was evaluated in seven patients aged 76-87 yr and in seven patients aged 27-57 yr. When elderly patients were compared with younger controls, the elderly exhibited a statistically significant decreased plasma clearance (5.9 +/- ...

journal_title：Anesthesia and analgesia

authors： Matteo RS,Young WL,Ornstein E,Schwartz AE,Silverberg PA,Diaz J

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to identify patient and procedural characteristics associated with postoperative respiratory depression or sedation requiring naloxone intervention. METHODS:We identified patients who received naloxone to reverse opioid-induced respiratory depression or sedation within 48 hours aft...

journal_title：Anesthesia and analgesia

authors： Weingarten TN,Herasevich V,McGlinch MC,Beatty NC,Christensen ED,Hannifan SK,Koenig AE,Klanke J,Zhu X,Gali B,Schroeder DR,Sprung J

更新日期：2015-08-01 00:00:00

abstract：:We compared the systemic toxicity of bupivacaine, levobupivacaine, and ropivacaine in anesthetized rats. We also compared the ability to resuscitate rats after lethal doses of these local anesthetics. Bupivacaine, levobupivacaine, or ropivacaine was infused at a rate of 2 mg. kg(-1). min(-1) while electrocardiogram, e...

journal_title：Anesthesia and analgesia

authors： Ohmura S,Kawada M,Ohta T,Yamamoto K,Kobayashi T

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Cell-free hemoglobin (Hb) forms in stored red blood cells (RBCs) as a result of hemolysis. Studies suggest that this cell-free Hb may decrease nitric oxide (NO) bioavailability, potentially leading to endothelial dysfunction, vascular injury, and multiorgan dysfunction after transfusion. We tested the hypoth...

journal_title：Anesthesia and analgesia

authors： Nagababu E,Scott AV,Johnson DJ,Goyal A,Lipsitz JA,Barodka VM,Berkowitz DE,Frank SM

更新日期：2016-08-01 00:00:00

abstract：:The extent of sensory and motor blockades was examined in 195 patients 5 and 20 min after four different techniques of brachial plexus block using 50 ml of 0.5% bupivacaine. The interscalene technique of Winnie (N = 50) resulted in a preferential blockade of the caudad portions of the cervical plexus and the cephalad ...

journal_title：Anesthesia and analgesia

authors： Lanz E,Theiss D,Jankovic D

更新日期：1983-01-01 00:00:00

abstract：:To improve operating room workflow, an internal transfer pricing system (ITPS) for anesthesia services was introduced in our hospital in 2001. The basic principle of the ITPS is that the department of anesthesia receives reimbursement only for the surgically controlled time, not for anesthesia-controlled time (ACT). A...

journal_title：Anesthesia and analgesia

authors： Schuster M,Standl T,Reissmann H,Kuntz L,Am Esch JS

更新日期：2005-07-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) is a significant cause of morbidity and mortality in the intensive care unit (ICU) and is characterized by lung epithelial and endothelial cell injury, with increased permeability of the alveolar-capillary membrane, leading to pulmonary edema, severe hypoxia, and difficulty w...

journal_title：Anesthesia and analgesia

authors： Lee LK,Medzikovic L,Eghbali M,Eltzschig HK,Yuan X

更新日期：2020-11-01 00:00:00

abstract：:To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane. After the injection of succinylcholine (0.3 mg/kg), cardiac arrhythmias occurred in al...

journal_title：Anesthesia and analgesia

authors： Leiman BC,Katz J,Butler BD

更新日期：1987-12-01 00:00:00

abstract：:Common practice during local anesthetic injection is to warn the patient using words such as: "You will feel a big bee sting; this is the worst part." Our hypothesis was that using gentler words for administration of the local anesthetic improves pain perception and patient comfort. One hundred forty healthy women at ...

journal_title：Anesthesia and analgesia

authors： Varelmann D,Pancaro C,Cappiello EC,Camann WR

更新日期：2010-03-01 00:00:00

abstract：UNLABELLED:We evaluated, by using a before-and-after study, the influence of leukoreduction by filtration on postoperative infections and adverse outcomes in patients undergoing elective major aortic surgery. From January 1995 to October 2000, all patients who underwent elective abdominal aortic surgery were included i...

journal_title：Anesthesia and analgesia

authors： Baron JF,Gourdin M,Bertrand M,Mercadier A,Delort J,Kieffer E,Coriat P

更新日期：2002-03-01 00:00:00

abstract：UNLABELLED:We sought to determine whether acute experimental allergic encephalomyelitis (EAE) alters the incorporation of epidurally administered [(3)H]-D-mannitol and [(14)C]-carboxyl-inulin into the lumbar spinal cord in rabbits. Acute EAE is an experimental model for demyelinating spinal cord diseases such as multip...

journal_title：Anesthesia and analgesia

authors： Naidu KA,Fu ES,Prockop LD

更新日期：2002-01-01 00:00:00

abstract：:Rapid sequence induction and intubation (RSII) and awake tracheal intubation are commonly used anesthetic techniques in patients at risk of pulmonary aspiration of gastric or esophageal contents. Some of these patients may have a gastric tube (GT) placed preoperatively. Currently, there are no guidelines regarding whi...

journal_title：Anesthesia and analgesia

authors： Salem MR,Khorasani A,Saatee S,Crystal GJ,El-Orbany M

更新日期：2014-03-01 00:00:00

abstract：:The effects of volatile anesthetics on arterial mechanical properties in vivo are incompletely understood. The present investigation tested the hypothesis that isoflurane and halothane cause differential actions on the mechanical characteristics of the aorta in barbiturate-anesthetized dogs instrumented for measuremen...

journal_title：Anesthesia and analgesia

authors： Hettrick DA,Pagel PS,Warltier DC

更新日期：1996-12-01 00:00:00

abstract：:We were interested in determining the effect of enflurane, halothane, and isoflurane on the uptake and removal of 5-hydroxytryptamine (5-HT) and phenylethylamine (PEA) from the lung. Isolated rabbit lungs were perfused in a recirculating system in vitro with 0.1 microM [14C]5-HT or 0.1 microM [14C]PEA in Krebs-Ringer ...

journal_title：Anesthesia and analgesia

authors： Cook DR,Brandom BW

更新日期：1982-08-01 00:00:00

abstract：:Postoperative sensitivity to tactile stimuli differs as a function of age. In this study, we hypothesized that preoperative sciatic nerve block (SNB), by providing preemptive analgesia, would result in better analgesia than postoperative SNB in the young rat. With the paw incision model of postoperative pain, male Spr...

journal_title：Anesthesia and analgesia

authors： Ririe DG,Barclay D,Prout H,Tong C,Tobin JR,Eisenach JC

更新日期：2004-07-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：:The aim of the present study was to investigate the impact of isoflurane on regional neurogenic mechanisms in the control of vascular tone. Therefore, regional determinations of sympathetic activity and hemodynamics were made in chloralose-anesthetized swine before and during administration of 1.4% isoflurane. Sympath...

journal_title：Anesthesia and analgesia

authors： Aneman A,Pontén J,Fändriks L,Eisenhofer G,Friberg P,Biber B

更新日期：1995-01-01 00:00:00

abstract：:Our overall goal was to investigate the mechanism by which fentanyl attenuates acetylcholine-induced contraction in porcine coronary artery. We tested the hypothesis that fentanyl attenuates muscarinic coronary contraction via sigma receptor activation. Left coronary artery vascular rings were isolated from porcine he...

journal_title：Anesthesia and analgesia

authors： Tsuchida H,Schubert A,Estafanous FG,Brum JM,Murray PA

更新日期：1996-05-01 00:00:00

abstract：:Endocardial motion and surface/volume changes during the cardiac cycle are echocardiographic methods for regional (analysis of wall motion) and global (fractional area change, stroke volume, and ejection fraction) evaluation of cardiac function. These conventional methods can be subjective, and/or time consuming and, ...

journal_title：Anesthesia and analgesia

authors： Skubas N

更新日期：2009-01-01 00:00:00

abstract：:In this study we attempted to define the minimal dosage of alfentanil (AF) needed in combination with nitrous oxide to provide satisfactory anesthetic conditions for lower abdominal gynecologic surgery. General anesthesia was induced in 12 women with AF (150 micrograms X kg-1) and 66% N2O in O2. An infusion of AF was ...

journal_title：Anesthesia and analgesia

authors： Ausems ME,Hug CC Jr,de Lange S

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Near-infrared spectroscopy is used during cardiac surgery to monitor the adequacy of cerebral perfusion. In this systematic review, we evaluated available data for adult patients to determine (1) whether decrements in cerebral oximetry during cardiac surgery are associated with stroke, postoperative cognitiv...

journal_title：Anesthesia and analgesia

authors： Zheng F,Sheinberg R,Yee MS,Ono M,Zheng Y,Hogue CW

更新日期：2013-03-01 00:00:00

abstract：:Windup is a progressive increase in responses of nociceptive spinal cord neurons to repeated electrical C fiber stimulation. We hypothesized that isoflurane would depress windup at approximately the minimum alveolar anesthetic concentration (MAC) required to suppress purposeful movement in response to noxious stimulat...

journal_title：Anesthesia and analgesia

authors： Jinks SL,Antognini JF,Dutton RC,Carstens E,Eger EI 2nd

更新日期：2004-11-01 00:00:00

abstract：UNLABELLED:Supraclavicular nerve blocks are effective but may be complicated by pneumothorax. We hypothesized that, to avoid this complication, the depths of the brachial plexus and the lung could be estimated to guide needle placement. In 17 patients undergoing surgical relief of thoracic outlet syndrome, we designate...

journal_title：Anesthesia and analgesia

authors： Cornish PB,Greenfield LJ,O'Reilly M,Allan L

更新日期：1999-05-01 00:00:00

abstract：:Dr. Paul Janssen was the founder of Janssen Pharmaceutica and the developer of over 80 pharmaceutical compounds that proved useful in human, botanical, and veterinary medicine. He and his coworkers synthesized the fentanyl family of drugs, many other potent analgesics, droperidol, etomidate, and numerous other importa...

journal_title：Anesthesia and analgesia

authors： Stanley TH,Egan TD,Van Aken H

更新日期：2008-02-01 00:00:00

abstract：UNLABELLED:In this study, we sought to determine the minimum analgesic doses and relative potencies of fentanyl and sufentanil when they are used as the sole epidural analgesic during the first stage of labor. Nulliparous parturients (n = 66) in spontaneous labor at term gestation and requesting epidural analgesia were...

journal_title：Anesthesia and analgesia

authors： Capogna G,Camorcia M,Columb MO

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:In this study, we compared the effect of light sedation with remifentanil versus propofol on intracranial (ICP) and cerebral perfusion pressure (CPP) of patients undergoing stereotactic brain tumor biopsy under regional anesthesia. METHODS:This was a prospective, open-label, randomized, and controlled study...

journal_title：Anesthesia and analgesia

authors： Girard F,Moumdjian R,Boudreault D,Chouinard P,Bouthilier A,Ruel M

更新日期：2009-07-01 00:00:00

abstract：UNLABELLED:Nasotracheal intubation is often required during dental and maxillofacial surgery. The complications of nasotracheal intubation are well documented, but there have been few systematic attempts to find methods for their prevention. We examined intubation-related carriage of bacteria, especially methicillin-re...

journal_title：Anesthesia and analgesia

authors： Takahashi S,Minami K,Ogawa M,Miyamoto H,Ikemura K,Shigematsu A,Taniguchi H

更新日期：2003-07-01 00:00:00

abstract：UNLABELLED:The aim of this study was to examine the antiallodynic and antinociceptive effects of subcutaneously administered physostigmine (50, 100, 200 micrograms/kg), compared with morphine (2.5, 5, 10 mg/kg) and NaCl after spinal nerve ligation in rats. The following stimuli were used: acetone (cold allodynia), von ...

journal_title：Anesthesia and analgesia

authors： Pöyhiä R,Xu M,Kontinen VK,Paananen S,Kalso E

更新日期：1999-08-01 00:00:00

abstract：:Perioperative thermal manipulations are usually directed at the skin surface because methods of directly warming the core are invasive or ineffective. However, inadequate heat flow between peripheral and core compartments will decrease the rate at which core temperature changes. We therefore determined whether core hy...

journal_title：Anesthesia and analgesia

authors： Plattner O,Xiong J,Sessler DI,Schmied H,Christensen R,Turakhia M,Dechert M,Clough D

更新日期：1996-05-01 00:00:00