A tribute to Dr. Paul A. J. Janssen: entrepreneur extraordinaire, innovative scientist, and significant contributor to anesthesiology.

abstract：IMPLICATIONS:Clinical productivity measurements that account for differences in clinical settings and concurrencies provided more precise comparisons between two anesthesiology groups. The data show that different concurrencies confound the current industry standard, "per full-time equivalent" measurements, whereas "pe...

journal_title：Anesthesia and analgesia

authors： Abouleish AE,Prough DS,Zornow MH,Lockhart A,Abate JJ,Hughes J

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine is a highly selective alpha(2)-agonist with hypnotic, analgesic, and anxiolytic properties. In adults, it provides sedation while preserving respiratory function facilitating extubation. Only limited pharmacokinetic data are available for pediatric patients. The primary aim of this study was ...

journal_title：Anesthesia and analgesia

authors： Su F,Nicolson SC,Gastonguay MR,Barrett JS,Adamson PC,Kang DS,Godinez RI,Zuppa AF

更新日期：2010-05-01 00:00:00

abstract：:The aim of this study was to correlate pupillary diameter with respiratory depression for 20 hr after epidural administration of morphine or buprenorphine. Pupillary diameter and the ventilatory sensitivity to CO2 were measured in six healthy volunteers at various times (0, 0.5, 1, 2, 3, 4, 6, 8, 10, 12, and 20 hr) in...

journal_title：Anesthesia and analgesia

authors： Ravnborg M,Jensen FM,Jensen NH,Holk IK

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:It remains unknown whether continuous or scheduled intermittent bolus local anesthetic administration is preferable for transversus abdominis plane (TAP) catheters. We therefore tested the hypothesis that when using TAP catheters, providing local anesthetic in repeated bolus doses increases the cephalad-caud...

journal_title：Anesthesia and analgesia

authors： Khatibi B,Said ET,Sztain JF,Monahan AM,Gabriel RA,Furnish TJ,Tran JT,Donohue MC,Ilfeld BM

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Superoxide, nitric oxide (NO), and peroxynitrite are important mediators in the pathogenesis of ischemia-reperfusion (I/R) injury. We tested the renoprotective effects of allopurinol (ALP), a xanthine oxidase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), and 5,10,15,20-tetrakis (N-methyl-4-pyridyl) po...

journal_title：Anesthesia and analgesia

authors： Choi EK,Jung H,Kwak KH,Yi SJ,Lim JA,Park SH,Park JM,Kim S,Jee DL,Lim DG

更新日期：2017-01-01 00:00:00

abstract：UNLABELLED:We evaluated in a qualitative systematic review the effect of N-methyl-D-aspartate (NMDA) receptor antagonists on reducing postoperative pain and analgesic consumption beyond the clinical duration of action of the target drug (preventive analgesia). Randomized trials examining the use of an NMDA antagonist i...

journal_title：Anesthesia and analgesia

authors： McCartney CJ,Sinha A,Katz J

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Growing awareness of the negative impacts from the practice of health care on the environment and public health calls for the routine inclusion of life cycle criteria into the decision-making process of device selection. Here we present a life cycle assessment of 2 laryngeal mask airways (LMAs), a one-time-u...

journal_title：Anesthesia and analgesia

authors： Eckelman M,Mosher M,Gonzalez A,Sherman J

更新日期：2012-05-01 00:00:00

abstract：:We considered the allocation of operating room (OR) time at facilities where the strategic decision had been made to increase the number of ORs. Allocation occurs in two stages: a long-term tactical stage followed by short-term operational stage. Tactical decisions, approximately 1 yr in advance, determine what specia...

journal_title：Anesthesia and analgesia

authors： Dexter F,Ledolter J,Wachtel RE

更新日期：2005-05-01 00:00:00

abstract：:Agreement between estimated fibrinogen concentration via thromboelastography and traditional assays is not established in the parturient. We therefore recruited 56 parturients and performed Clauss and functional fibrinogen level (FLEV) tests. Mean difference of measurements was 36.8 mg/dL (95% CI, 21.8-51.9) with a st...

journal_title：Anesthesia and analgesia

authors： Katz D,Hamburger J,Batt D,Zahn J,Beilin Y

更新日期：2019-09-01 00:00:00

abstract：:The aim of this prospective, randomized, controlled clinical trial was to define the opioid analgesic requirement after a remifentanil (REMI)-based anesthetic with spinal anesthetic blockade (SAB+REMI) or without (REMI) spinal blockade for open-heart surgery in children. We enrolled 45 patients who were candidates for...

journal_title：Anesthesia and analgesia

authors： Hammer GB,Ramamoorthy C,Cao H,Williams GD,Boltz MG,Kamra K,Drover DR

更新日期：2005-05-01 00:00:00

abstract：UNLABELLED:Sudden profound hypotensive and/or bradycardic events (HBE) have been reported in >20% of patients undergoing shoulder arthroscopy in the sitting position under interscalene block anesthesia. Retrospective studies suggest that the administration of beta-blockers is safe and may decrease the incidence of thes...

journal_title：Anesthesia and analgesia

authors： Liguori GA,Kahn RL,Gordon J,Gordon MA,Urban MK

更新日期：1998-12-01 00:00:00

abstract：IMPLICATIONS:We report the successful use of the laryngeal mask airway for percutaneous endoscopic gastrostomy in an adult patient with a known difficult airway and severe cerebral palsy. ...

journal_title：Anesthesia and analgesia

authors： Brimacombe J,Newell S,Bergin A,McCarthy J,Barry J

更新日期：2000-09-01 00:00:00

abstract：:We studied the time to postoperative micturition and the duration of analgesia in 82 children aged 6 mo to 10 yr undergoing herniorrhaphy or orchiopexy under general anesthesia with N2O and halothane. All received D5 lactate Ringer's solution equivalent to 6 h maintenance intraoperatively, and oral fluids postoperativ...

journal_title：Anesthesia and analgesia

authors： Fisher QA,McComiskey CM,Hill JL,Spurrier EA,Voigt RE,Savarese AM,Beaver BL,Boltz MG

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine, an α(2)-receptor agonist, prolongs analgesia when used in neuraxial and IV blocks. We evaluated the effect of dexmedetomidine added to ropivacaine for tibial nerve block on the duration of the sensory blockade. METHODS:For this prospective, randomized, controlled, double-blind, crossover tr...

journal_title：Anesthesia and analgesia

authors： Rancourt MP,Albert NT,Côté M,Létourneau DR,Bernard PM

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Transversus abdominis plane (TAP) block and local anesthetic wound infiltration provide analgesia after cesarean delivery. Studies comparing the 2 techniques are scarce, with conflicting results. This double-blind, randomized controlled trial aimed to compare bilateral ultrasound-guided TAP block with single...

journal_title：Anesthesia and analgesia

authors： Tawfik MM,Mohamed YM,Elbadrawi RE,Abdelkhalek M,Mogahed MM,Ezz HM

更新日期：2017-04-01 00:00:00

abstract：UNLABELLED:Because anesthetic technique has the potential to dramatically affect cerebral blood flow and metabolism (two determinants of brain thermoregulation), we tested the hypothesis that, after craniotomy, anesthetic technique would influence brain temperature independent of core temperature. Twenty-one cats (2.7 ...

journal_title：Anesthesia and analgesia

authors： Erickson KM,Lanier WL

更新日期：2003-05-01 00:00:00

abstract：:Propofol is associated with a low incidence of postoperative nausea and vomiting. In a prospective, randomized, double-blind, placebo-controlled study, we investigated the possible direct antiemetic properties of a subhypnotic dose of propofol. Fifty-two ASA physical status I or II patients, aged 15-60 yr with nausea ...

journal_title：Anesthesia and analgesia

authors： Borgeat A,Wilder-Smith OH,Saiah M,Rifat K

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Respiratory variations in arterial pulse pressure (DeltaPP) are accurate predictors of fluid responsiveness in mechanically ventilated patients. The aim of our study was to assess the ability of a novel algorithm for automatic estimation of stroke volume variation (SVV) to predict fluid responsiveness in mec...

journal_title：Anesthesia and analgesia

authors： Cannesson M,Musard H,Desebbe O,Boucau C,Simon R,Hénaine R,Lehot JJ

更新日期：2009-02-01 00:00:00

abstract：:The purpose of the present study was to quantify the inhibitory effect of inhaled halothane and isoflurane on acute hypercapnia-induced responses of capacitance-regulating veins and related cardiovascular variables in response to sequential 40-s periods of 5%, 10%, 15%, and 20% inspired CO2 (FICO2). Measurements were ...

journal_title：Anesthesia and analgesia

authors： Stekiel TA,Stekiel WJ,Tominaga M,Stadnicka A,Bosnjak ZJ,Kampine JP

更新日期：1996-02-01 00:00:00

abstract：:The acute central nervous and cardiovascular effects of the local anesthetics ropivacaine and bupivacaine were compared in 12 volunteers in a randomized double-blind manner with use of intravenous infusions at a rate of 10 mg/min up to a maximal dose of 150 mg. The volunteers were all healthy men. They were familiariz...

journal_title：Anesthesia and analgesia

authors： Scott DB,Lee A,Fagan D,Bowler GM,Bloomfield P,Lundh R

更新日期：1989-11-01 00:00:00

abstract：UNLABELLED:Shoulder surgery is often performed with patients in the sitting position under interscalene block anesthesia. Vasovagal episodes, characterized by a sudden decrease in heart rate and/or blood pressure, have a reported incidence of 17%-24% in this setting. We performed a retrospective study to determine whet...

journal_title：Anesthesia and analgesia

authors： Kahn RL,Hargett MJ

更新日期：1999-02-01 00:00:00

abstract：UNLABELLED:Mitral regurgitation (MR) is a major determinant of outcome in cardiac surgery. The location and mechanism of mitral lesions determine the approach to various repairs and their feasibility. Because of incomplete evaluations or change in patient condition, detailed intraoperative transesophageal echocardiogra...

journal_title：Anesthesia and analgesia

authors： Lambert AS,Miller JP,Merrick SH,Schiller NB,Foster E,Muhiudeen-Russell I,Cahalan MK

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Neuropathic pain is a result of a primary lesion or dysfunction of the peripheral or central nervous system, and its treatment is challenging. Animal models have been helpful in understanding mechanisms of neuropathic pain and in developing new treatment strategies. In this study, we examined the effect of p...

journal_title：Anesthesia and analgesia

authors： Ozsoylar O,Akçali D,Cizmeci P,Babacan A,Cahana A,Bolay H

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Topical anesthesia of the upper airway is often recommended when difficulty in airway management is anticipated. There are published reports, however, of administration of topical anesthesia resulting in complete loss of airway control. Adverse effects are mostly attributed to interference with involuntary p...

journal_title：Anesthesia and analgesia

authors： Maxwell MJ,English JD,Moppett IK,McGlashan JA,Norris AM

更新日期：2012-04-01 00:00:00

abstract：IMPLICATIONS:We describe a technique of one-lung high-frequency jet ventilation surgery with continuous monitoring of airway pressures that achieves satisfactory operating conditions with less complications than other similar approaches. ...

journal_title：Anesthesia and analgesia

authors： Unzueta MC,Casas I,Merten A,Landeira JM

更新日期：2003-01-01 00:00:00

abstract：:The hemodynamic effects of mivacurium chloride were studied in 54 adult cardiac patients anesthetized with midazolam and sufentanil. After baseline data were collected, a placebo (N = 9) or mivacurium was administered over 60 seconds, the latter in doses of 0.15 (N = 18), 0.20 (N = 18), or 0.25 (N = 9) mg/kg. Measurem...

journal_title：Anesthesia and analgesia

authors： Stoops CM,Curtis CA,Kovach DA,McCammon RL,Stoelting RK,Warren TM,Miller D,Bopp SK,Jugovic DJ,Abou-Donia MM

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Acute renal failure is a frequent complication of sepsis. Hydroxyethyl starch (HES) is widely used in the treatment of such patients. However, the effect of HES on renal function during sepsis remains controversial. We established an in vitro model of tumor necrosis factor-alpha (TNF-alpha)-stimulated human ...

journal_title：Anesthesia and analgesia

authors： Wittlinger M,Schläpfer M,De Conno E,Z'graggen BR,Reyes L,Booy C,Schimmer RC,Seifert B,Burmeister MA,Spahn DR,Beck-Schimmer B

更新日期：2010-02-01 00:00:00

abstract：:To evaluate the effects of high-frequency jet ventilation (HFJV) (f = 60, 120 breaths/min) and conventional mechanical ventilation (CMV) (f = 10, 20) during equivalent conditions of cardiac tamponade, stroke index (SI), intrapericardial pressure (IPP), airway pressure (P(aw)), and cardiac pressures were measured in an...

journal_title：Anesthesia and analgesia

authors： Goto K,Goto H,Benson KT,Unruh GK,Arakawa K

更新日期：1990-04-01 00:00:00

abstract：UNLABELLED:Brain dysfunction after cardiopulmonary bypass (CPB) is common, and it has been hypothesized that this injury might be due partly to activation of inflammatory processes in the brain. We measured juguloarterial gradients for interleukin-1beta, interleukin-6, and interleukin-8 (IL-8) as indices of local proin...

journal_title：Anesthesia and analgesia

authors： Nandate K,Vuylsteke A,Crosbie AE,Messahel S,Oduro-Dominah A,Menon DK

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Sigma (sigma)-receptor agonists attenuate brain injury after experimental focal cerebral ischemia in several species. We tested the hypothesis that the potent, prototypical sigma(1)-receptor agonist, 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP), protects neurons by a mechanism involving the antiapoptotic pro...

journal_title：Anesthesia and analgesia

authors： Yang S,Bhardwaj A,Cheng J,Alkayed NJ,Hurn PD,Kirsch JR

更新日期：2007-05-01 00:00:00