Pharmacokinetics and pharmacodynamics of edrophonium in elderly surgical patients.

abstract：BACKGROUND:In patients undergoing total knee arthroplasty under spinal anesthesia, we compared the postoperative analgesic effect of intraoperative sedation with dexmedetomidine versus propofol. We hypothesized that sedation with dexmedetomidine would result in lower postoperative opioid analgesic consumption than with...

journal_title：Anesthesia and analgesia

authors： Shin HJ,Do SH,Lee JS,Kim TK,Na HS

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Whether nitrous oxide (N(2)O) increases the incidence of postoperative nausea and vomiting (PONV) after laparoscopic gynecologic surgery is still controversial, which may be due to the administration of different concentrations of inspired N(2)O. We investigated whether N(2)O results in a dose-response incre...

journal_title：Anesthesia and analgesia

authors： Mraovic B,Simurina T,Sonicki Z,Skitarelic N,Gan TJ

更新日期：2008-09-01 00:00:00

abstract：:Hemiplegic migraine is a condition associated with vascular alteration of the central nervous system and transient neurologic deficits. Permanent morphine-induced motor dysfunction has been reported after spinal ischemia. We report a persisting central neurological deficit after single-dose spinal administration of 40...

journal_title：Anesthesia and analgesia

authors： Lentschener C,Dousset B,Zuber M,Ozier Y

更新日期：2009-11-01 00:00:00

abstract：UNLABELLED:Besides having important hormonal effects, progesterone has depressant and hypnotic effects on the brain. In this study, we compared women in the follicular phase with low progesterone levels and in the luteal phase with high progesterone levels regarding their anesthetic requirements. Twenty patients with m...

journal_title：Anesthesia and analgesia

authors： Erden V,Yangin Z,Erkalp K,Delatioğlu H,Bahçeci F,Seyhan A

更新日期：2005-10-01 00:00:00

abstract：:We evaluated empirically the extent to which the use of a cognitive aid during a high-fidelity simulation of a malignant hyperthermia (MH) event facilitated the correct and prompt treatment of MH. We reviewed the management of 48 simulated adult MH scenarios; 24 involving CA 1 and 24 involving CA 2 residents. In the C...

journal_title：Anesthesia and analgesia

authors： Harrison TK,Manser T,Howard SK,Gaba DM

更新日期：2006-09-01 00:00:00

abstract：:As most of us are aware, almost every facet of our society is becoming, for better or worse, progressively more technology-dependent. Technological advancement has made autonomous systems, also known as robots, an integral part of our life in several fields, including medicine. The application of robots in anesthesia ...

journal_title：Anesthesia and analgesia

authors： Zaouter C,Joosten A,Rinehart J,Struys MMRF,Hemmerling TM

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Microdialysis studies have demonstrated that the release of serotonin (5-hydroxytryptamine, 5-HT) in the serotonergic projection areas increases during waking and decreases during sleep in rat and cat, suggesting that 5-HT plays an important role in modulation of sleep. Although it might be expected that 5-H...

journal_title：Anesthesia and analgesia

authors： Mukaida K,Shichino T,Koyanagi S,Himukashi S,Fukuda K

更新日期：2007-04-01 00:00:00

abstract：IMPLICATIONS:Manipulating the density of local anesthetic solutions by using a simple formula may be clinically useful in producing optimal density solutions for spinal anesthesia under a variety of clinical conditions. ...

journal_title：Anesthesia and analgesia

authors： Hallworth SP,Fernando R,Stocks GM

更新日期：2002-06-01 00:00:00

abstract：:We studied the effect of intravenous (IV) thiamylal or ketamine on the increases in serum myoglobin, creatine kinase (CK), and potassium induced by succinylcholine under halothane anesthesia. Ninety patients were divided into three groups. In Group O, succinylcholine (1.0 mg/kg) was administered after an the inhaled i...

journal_title：Anesthesia and analgesia

authors： Noguchi I,Sankawa H,Andou M

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Many clinical pain states that are difficult to treat share a common feature of sensitization of nociceptive pathways. Drugs that could normalize hyperexcitable neural activity (e.g., antiepileptic drugs) may be useful in relieving these pain states. Eslicarbazepine acetate (ESL) is a novel antiepileptic dru...

journal_title：Anesthesia and analgesia

authors： Tomić MA,Pecikoza UB,Micov AM,Stepanović-Petrović RM

更新日期：2015-12-01 00:00:00

abstract：UNLABELLED:Combined spinal-epidural anesthesia (CSE) is a popular technique for cesarean delivery. Regional blocks in obstetrics are often performed with the parturient in the sitting position because the midline may be recognized more easily than in the lateral decubitus position. When conventional spinal anesthesia i...

journal_title：Anesthesia and analgesia

authors： Yun EM,Marx GF,Santos AC

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Nerve injury can generate neuropathic pain. The accompanying mechanical allodynia may be reduced by the intrathecal administration of adenosine. The neuroprotective effects of adenosine are mediated by the adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channel. We assessed the relationship between...

journal_title：Anesthesia and analgesia

authors： Song JG,Hahm KD,Kim YK,Leem JG,Lee C,Jeong SM,Park PH,Shin JW

更新日期：2011-06-01 00:00:00

abstract：:In recent years the off-label use of recombinant activated factor VII (rFVIIa) has markedly increased, particularly in pediatric cardiac surgery patients, and practitioners differ widely in their usage of the drug. In 2009, the Congenital Cardiac Anesthesia Society (CCAS) assembled a task force to review the literatur...

journal_title：Anesthesia and analgesia

authors： Guzzetta NA,Russell IA,Williams GD

更新日期：2012-08-01 00:00:00

abstract：:In a randomized study, we evaluated lag time (time from the end of injection of muscle relaxant until the first depression of the train-of-four response [TOF]), onset time (time from the end of injection of muscle relaxant until the maximum depression of the first twitch of the TOF [T1]), neuromuscular block, and endo...

journal_title：Anesthesia and analgesia

authors： Wierda JM,van den Broek L,Proost JH,Verbaan BW,Hennis PJ

更新日期：1993-09-01 00:00:00

abstract：:Substance P, a neuropeptide associated with pain perception, is widely distributed in the central nervous system and is decreased in the cerebrospinal fluid of chronic pain patients as compared with that of healthy human volunteers. In this study, we have demonstrated the presence of immunoreactive substance P in sali...

journal_title：Anesthesia and analgesia

authors： Parris WC,Kambam JR,Naukam RJ,Rama Sastry BV

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Among the various factors influencing the success rate, onset time, and duration of peripheral nerve blocks, the role of local anesthetics concentration remains uncertain. In this prospective, randomized, single-blinded study, we evaluated whether varying the dilution of a fixed dose of mepivacaine solution ...

journal_title：Anesthesia and analgesia

authors： Cappelleri G,Ambrosoli AL,Turconi S,Gemma M,Ricci EB,Cornaggia G

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:The proportion of live births by cesarean delivery (CD) in China is significant, with some, particularly rural, provinces reporting up to 62.5%. The No Pain Labor & Delivery-Global Health Initiative (NPLD-GHI) was established to improve obstetric and neonatal outcomes in China, including through a reduction ...

journal_title：Anesthesia and analgesia

authors： Drzymalski DM,Guo JC,Qi XQ,Tsen LC,Sun Y,Ouanes JP,Xia Y,Gao WD,Ruthazer R,Hu F,Hu LQ

更新日期：2020-04-22 00:00:00

abstract：:Many inhaled anesthetics and intravenous analgesics have been alleged to produce both proconvulsant and anticonvulsant activity in humans. The reasons for these contrasting actions on the CNS are poorly understood at the present time. However, biologic variability plays an important role in determining individual pati...

journal_title：Anesthesia and analgesia

authors： Modica PA,Tempelhoff R,White PF

更新日期：1990-03-01 00:00:00

abstract：:Early tracheal extubation has been safely performed after large operative procedures, questioning the need for routine postoperative ventilation. Because immediate postoperative tracheal extubation of liver transplantation patients has not been previously reported, we performed preliminary studies at two institutions ...

journal_title：Anesthesia and analgesia

authors： Mandell MS,Lockrem J,Kelley SD

更新日期：1997-02-01 00:00:00

abstract：:We investigated the characteristics of hypoxemic fetoplacental vasoconstriction (HFPV) in the dual perfused, single isolated human placental cotyledon. Fetal arterial blood pressures (FAP) were measured in four cotyledons (Group 1) equilibrated with 21% oxygen (O2), 5% carbon dioxide (CO2), and nitrogen (N2) [control]...

journal_title：Anesthesia and analgesia

authors： Ramasubramanian R,Johnson RF,Downing JW,Minzter BH,Paschall RL

更新日期：2006-08-01 00:00:00

abstract：:In this prospective, randomized, placebo-controlled, double-blind trial we studied the effects of IV N-acetylcysteine for prevention of renal injury in patients undergoing abdominal aortic surgery. Seventy patients without previously documented renal dysfunction were randomly allocated to receive either N-acetylcystei...

journal_title：Anesthesia and analgesia

authors： Hynninen MS,Niemi TT,Pöyhiä R,Raininko EI,Salmenperä MT,Lepäntalo MJ,Railo MJ,Tallgren MK

更新日期：2006-06-01 00:00:00

abstract：IMPLICATIONS:We report a unique case of acute anaphylaxis after mediastinal irrigation with a dilute bacitracin solution. ...

journal_title：Anesthesia and analgesia

authors： Blas M,Briesacher KS,Lobato EB

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Current guidelines from the American College of Obstetricians and Gynecologists recommend antibiotic prophylaxis for cesarean delivery immediately before incision. The purpose of this study was to measure and describe correlates of adherence to these guidelines in a sample of United States anesthesiologists....

journal_title：Anesthesia and analgesia

authors： Raghunathan K,Connelly NR,Friderici J,Naglieri-Prescod D,Joyce R,Prasanna P,Ponnusamy N

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The intrathoracic blood volume index (ITBVI) and central venous pressure (CVP) are routinely used to predict fluid responsiveness in critically ill patients with acute circulatory failure (systolic blood pressure < 90 mm Hg or vasopressor requirement). However, they have never been compared. METHODS:In this...

journal_title：Anesthesia and analgesia

authors： Muller L,Louart G,Bengler C,Fabbro-Peray P,Carr J,Ripart J,de La Coussaye JE,Lefrant JY

更新日期：2008-08-01 00:00:00

abstract：:Patients undergoing potentially painful interventional radiological procedures generally require a combination of analgesia and sedation. This sedation/analgesia should allow the patient to communicate while also remaining calm. Bispectral index (BIS) monitoring could be useful in achieving this. The primary end-point...

journal_title：Anesthesia and analgesia

authors： Dahaba AA,Lischnig U,Kronthaler R,Bornemann H,Georgiev V,Rehak PH,Metzler H

更新日期：2006-08-01 00:00:00

abstract：UNLABELLED:Because succinylcholine has obvious advantages for facilitating endotracheal intubation in the ambulatory setting (e.g., low cost, fast onset, and no need for reversal of neuromuscular block), it is important to determine whether this muscle relaxant is indeed associated with an increased incidence of postop...

journal_title：Anesthesia and analgesia

authors： Mikat-Stevens M,Sukhani R,Pappas AL,Fluder E,Kleinman B,Stevens RA

更新日期：2000-08-01 00:00:00

abstract：:In chloralose-anesthetized dogs the hypotensive and reflex cardiovascular responses to infusions of sodium nitroprusside were studied before and during halothane and enflurane, and before after divided doses of cryptenamine. The latter drug, a mixture of hypotensive veratrum alkaloids, lowers blood pressure reflexly b...

journal_title：Anesthesia and analgesia

authors： Flacke JW,Flacke WE,Cant JW

更新日期：1980-12-01 00:00:00

abstract：:To clarify the effect of hematocrit on the solubility of volatile anesthetics in blood, we measured the blood-gas partition coefficients of isoflurane, enflurane, halothane, and methoxyflurane concurrently at 37 degrees C in blood from four adults. We measured the blood-gas partition coefficients in the plasma (hemato...

journal_title：Anesthesia and analgesia

authors： Lerman J,Gregory GA,Eger EI 2nd

更新日期：1984-10-01 00:00:00

abstract：UNLABELLED:As the surgical population ages, the number of patients presenting with coronary artery disease and age-related loss of pulmonary recoil will increase. Although their influence on gas exchange in this population remains unknown, sevoflurane and isoflurane are used for an increasing variety of surgical proced...

journal_title：Anesthesia and analgesia

authors： Loeckinger A,Keller C,Lindner KH,Kleinsasser A

更新日期：2002-05-01 00:00:00

abstract：UNLABELLED:One-lung ventilation (OLV) induces an increase in pulmonary shunt sometimes associated with a decrease in PaO2 despite ventilation with 100% oxygen. PaO2 improvement has been reported in one-lung ventilated animals receiving IV almitrine, a pulmonary vasoconstrictor. We evaluated the ability of almitrine to ...

journal_title：Anesthesia and analgesia

authors： Moutafis M,Dalibon N,Liu N,Kuhlman G,Fischler M

更新日期：2002-04-01 00:00:00