The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices.

abstract：BACKGROUND:Midazolam is the most commonly used premedication in children. It has been shown to be more effective than parental presence or placebo in reducing anxiety and improving compliance at induction of anesthesia. Clonidine, an alpha(2) agonist, has been suggested as an alternative. Dexmedetomidine is a more alph...

journal_title：Anesthesia and analgesia

authors： Yuen VM,Hui TW,Irwin MG,Yuen MK

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:In children, postoperative respiratory rate (RR) monitoring by transthoracic impedance (TI), capnography, and manual counting has limitations. The rainbow acoustic monitor (RAM) measures continuous RR noninvasively by a different methodology. Our primary aim was to compare the degree of agreement and accurac...

journal_title：Anesthesia and analgesia

authors： Patino M,Kalin M,Griffin A,Minhajuddin A,Ding L,Williams T,Ishman S,Mahmoud M,Kurth CD,Szmuk P

更新日期：2017-06-01 00:00:00

abstract：UNLABELLED:Adenosine and adenosine analogs induce analgesia in humans and presumed antinociception in animal models when administered both systemically and intrathecally. In the present investigation in rats, we studied the effects of intrathecally administered adenosine analogs, with or without systemic coadministrati...

journal_title：Anesthesia and analgesia

authors： Sjölund KF,Sollevi A,Segerdahl M,Lundeberg T

更新日期：1997-09-01 00:00:00

abstract：UNLABELLED:Linking physiological pharmacokinetic models to models of the cardiovascular system requires knowledge of the sites in the body that mediate a drug's cardiovascular effects. We examined the role of the coronary concentrations of propofol. Nine sheep anesthetized with isoflurane (2%) were instrumented acutely...

journal_title：Anesthesia and analgesia

authors： Zheng D,Upton RN,Martinez AM

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Cannabinoid agonists induce norepinephrine release in central, spinal, and peripheral sites. Previous studies suggest an interaction between the cannabinoid and adrenergic systems on antinociception. In this study, we sought to verify whether the CB1 and CB2 cannabinoid receptor agonists anandamide and N-pal...

journal_title：Anesthesia and analgesia

authors： Romero TR,Resende LC,Guzzo LS,Duarte ID

更新日期：2013-02-01 00:00:00

abstract：:The purpose of this study was to measure cardiac sympathetic nerve activity (CSNA) and atrioventricular (AV) conduction and to test the effects of dobutamine (DOB) and phenylephrine (PHE) on AV conduction during combined use of halothane and thoracic epidural lidocaine. Cats were anesthetized with 1 % halothane and an...

journal_title：Anesthesia and analgesia

authors： Nishikawa K,Yabe M,Mori T,Terai T,Yukioka H,Fujimori M

更新日期：1996-03-01 00:00:00

abstract：UNLABELLED:Endotracheal administration of epinephrine 0.02 mg/kg (twice the IV dose) is recommended when IV access is unavailable during cardiopulmonary resuscitation. The standard IV dose has been considered too small for the endotracheal route by causing a detrimental decrease of arterial blood pressure (BP), presuma...

journal_title：Anesthesia and analgesia

authors： Manisterski Y,Vaknin Z,Ben-Abraham R,Efrati O,Lotan D,Berkovitch M,Barak A,Barzilay Z,Paret G

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Chemical pleurodesis causes severe pain, prompting physicians to perform thoracoscopic talc poudrage under general or neuroleptanalgesia. We describe a novel method for pain control in five patients with pneumothoraces and severe chronic obstructive pulmonary disease. METHODS:Patients were premedicated with...

journal_title：Anesthesia and analgesia

authors： Lee P,Colt HG

更新日期：2007-01-01 00:00:00

abstract：UNLABELLED:Heart transplantation in patients with increased pulmonary vascular resistance is often associated with postbypass right heart failure. We therefore compared the abilities of prostaglandin E(1) (PGE(1)) and inhaled nitric oxide to reduce pulmonary vascular resistance during heart transplantation. Patients un...

journal_title：Anesthesia and analgesia

authors： Rajek A,Pernerstorfer T,Kastner J,Mares P,Grabenwöger M,Sessler DI,Grubhofer G,Hiesmayr M

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Platelet factor 4 (PF4) is released by activated platelets and has a strong affinity for heparin. Recombinant PF4 (rPF4) has been previously considered as an alternative to protamine for heparin reversal. However, it has been demonstrated that antibodies directed against the PF4/heparin moiety are important ...

journal_title：Anesthesia and analgesia

authors： Demma L,Levy JH

更新日期：2012-12-01 00:00:00

abstract：UNLABELLED:There are situations in anesthesia in which it may be desirable to achieve rapid tracheal intubation with perfect conditions, i.e., no coughing or straining. To determine the dose of rocuronium that gives a high probability of achieving perfect conditions for rapid (within 60 s) tracheal intubation, we admin...

journal_title：Anesthesia and analgesia

authors： Heier T,Caldwell JE

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Intraoperative hypotension is common and associated with organ injury and death, although randomized data showing a causal relationship remain sparse. A risk-adjusted measure of intraoperative hypotension may therefore contribute to quality improvement efforts. METHODS:The measure we developed defines hypot...

journal_title：Anesthesia and analgesia

authors： Christensen AL,Jacobs E,Maheshwari K,Xing F,Zhao X,Simon SE,Domino KB,Posner KL,Stewart AF,Sanford JA,Sessler DI

更新日期：2020-11-23 00:00:00

abstract：:We used laser-Doppler flowmetry to compare the effects of the volatile anesthetics, isoflurane and halothane, on the cerebrovascular response to CO2 inhalation in male Sprague-Dawley rats. The effects of 0.5 and 1.5 minimum alveolar anesthetic concentrations (MAC) of halothane and isoflurane on the microcirculatory re...

journal_title：Anesthesia and analgesia

authors： Lee JG,Smith JJ,Hudetz AG,Hillard CJ,Bosnjak ZJ,Kampine JP

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:In this study, we hypothesized that leg positioning and distal tourniquet application, when compared with neutral positioning of the leg, alters the efficacy of sciatic nerve block performed by the double-stimulation technique. METHODS:Ninety randomized, consecutive, ASA physical status I to III patients un...

journal_title：Anesthesia and analgesia

authors： Sertoz N,Deniz MN,Ayanoglu HO

更新日期：2011-12-01 00:00:00

abstract：UNLABELLED:Propofol (Diprivan(TM); AstraZeneca, Wilmington, DE) is a commonly used drug for the induction of general anesthesia in the ambulatory setting. With the availability of a new bisulfite-containing generic formulation of propofol, questions have arisen regarding its cost effectiveness and safety compared with ...

journal_title：Anesthesia and analgesia

authors： Shao X,Li H,White PF,Klein KW,Kulstad C,Owens A

更新日期：2000-10-01 00:00:00

abstract：UNLABELLED:N-methyl-D-aspartate (NMDA) antagonists, such as MK801, delay the development of morphine tolerance. Magnesium, a noncompetitive NMDA antagonist, reduces postoperative morphine requirements. The present study was designed to evaluate the effects of intrathecal co-administration of magnesium sulfate with morp...

journal_title：Anesthesia and analgesia

authors： McCarthy RJ,Kroin JS,Tuman KJ,Penn RD,Ivankovich AD

更新日期：1998-04-01 00:00:00

abstract：:Mitral valve replacement is frequently complicated by a low cardiac output syndrome and elevated pulmonary arterial pressures. In the present study, we used dobutamine to increase cardiac index and measured the pulmonary hemodynamic effects in 10 patients with increased pulmonary vascular tone following mitral valve r...

journal_title：Anesthesia and analgesia

authors： Schwenzer KJ,Miller ED Jr

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) is a commonly encountered comorbid condition in patients undergoing surgery and is associated with a greater risk of postoperative adverse events. Our objective in this review was to investigate the effectiveness of continuous positive airway pressure (CPAP) in reducing the risk...

journal_title：Anesthesia and analgesia

authors： Nagappa M,Mokhlesi B,Wong J,Wong DT,Kaw R,Chung F

更新日期：2015-05-01 00:00:00

abstract：:Phenomena seen in axons exposed to subblocking doses serve as the basis for interpreting clinical and behavioral observations during onset and recovery of peripheral nerve block. To delineate the changes in excitability and in impulse conduction caused by subblocking concentrations of local anesthetics (LAs) in myelin...

journal_title：Anesthesia and analgesia

authors： Raymond SA

更新日期：1992-12-01 00:00:00

abstract：:Anecdotal reports suggest that soda lime and Baralyme brand absorbent can degrade inhaled anesthetics to carbon monoxide (CO). We examined the factors that govern CO production and found that these include: 1) The anesthetic used: for a given minimum alveolar anesthetic concentration (MAC)-multiple, the magnitude of C...

journal_title：Anesthesia and analgesia

authors： Fang ZX,Eger EI 2nd,Laster MJ,Chortkoff BS,Kandel L,Ionescu P

更新日期：1995-06-01 00:00:00

abstract：:This consensus statement was commissioned in 2012 by the Board of Directors of the Society for Obstetric Anesthesia and Perinatology to improve maternal resuscitation by providing health care providers critical information (including point-of-care checklists) and operational strategies relevant to maternal cardiac arr...

journal_title：Anesthesia and analgesia

authors： Lipman S,Cohen S,Einav S,Jeejeebhoy F,Mhyre JM,Morrison LJ,Katz V,Tsen LC,Daniels K,Halamek LP,Suresh MS,Arafeh J,Gauthier D,Carvalho JC,Druzin M,Carvalho B,Society for Obstetric Anesthesia and Perinatology.

更新日期：2014-05-01 00:00:00

abstract：:The efficacy of two dosage regimens of intravenous naloxone were compared to avoid nonrespiratory side effects and respiratory depression and yet to preserve analgesia (maximum tolerance to periostial pressure over the tibia) after administration of 200 micrograms epidural fentanyl. Three groups of eight patients were...

journal_title：Anesthesia and analgesia

authors： Gueneron JP,Ecoffey Cl,Carli P,Benhamou D,Gross JB

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:As part of the Thai Anesthesia Incidents Study of anesthetic adverse outcomes, we evaluated the incidence and factors related to cardiac arrest during spinal anesthesia. METHODS:During a 12-mo period (March 1, 2003, to February 28, 2004), a prospective, multicenter registry of patients receiv...

journal_title：Anesthesia and analgesia

authors： Charuluxananan S,Thienthong S,Rungreungvanich M,Chanchayanon T,Chinachoti T,Kyokong O,Punjasawadwong Y

更新日期：2008-11-01 00:00:00

abstract：:Asymptomatic anemia in healthy patients undergoing low risk surgery is rare. In this retrospective study, we examined the records of 9584 ASA class I-II patients scheduled for elective low risk surgery who had a preoperative hemoglobin (hgb) test for the presence of anemia. Hgb <9 g/dL was detected in 75 patients (0.8...

journal_title：Anesthesia and analgesia

authors： Olson RP,Stone A,Lubarsky D

更新日期：2005-11-01 00:00:00

abstract：:Clonidine in spinal and epidural blocks prolongs anesthesia, but can cause hypotension and bradycardia. The aim of our study was to compare hemodynamic and analgesic effects of spinal versus epidural clonidine alone and after repetitive dosing. In a prospective, randomized, double-blind study, we evaluated 40 patients...

journal_title：Anesthesia and analgesia

authors： Klimscha W,Chiari A,Krafft P,Plattner O,Taslimi R,Mayer N,Weinstabl C,Schneider B,Zimpfer M

更新日期：1995-02-01 00:00:00

abstract：:The local anesthetic effects of opioids have been demonstrated in both clinical and laboratory studies. Clinically, both meperidine and sufentanil can produce segmental sensory anesthesia. However, previous studies of the effects of opioids on nerve conduction have all made use of peripheral nerve preparations and yie...

journal_title：Anesthesia and analgesia

authors： Jaffe RA,Rowe MA

更新日期：1996-10-01 00:00:00

abstract：:This study used the activated clotting time (ACT) to determine the clinical onset of four different doses of heparin after bolus injection into the central circulation. Ten consenting adults (Group A) undergoing coronary artery bypass grafting were given 350 U/kg of bovine lung heparin and had simultaneous duplicate a...

journal_title：Anesthesia and analgesia

authors： Heres EK,Speight K,Benckart D,Marquez J,Gravlee GP

更新日期：2001-06-01 00:00:00

abstract：:The development of a technique for studying spinal dorsal horn electrophysiology in intact, awake, drug-free cats enables the study of spinal sites and mechanisms of action of anesthetic and analgesic agents in a system that more closely reflects normal physiology. Using this technique, we reevaluated the effect of ke...

journal_title：Anesthesia and analgesia

authors： Collins JG

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor alpha (TNF-alpha) could trigger p38 mitogen-activated protein kinase (MAPK) activation. Conversely phosphorylated p38 (p-p38) could induce the upregulation of TNF-alpha. In this study, we examined the hypothesis that chronic constrictive injury (CCI) of the sciatic nerve could promote s...

journal_title：Anesthesia and analgesia

authors： Xu L,Huang Y,Yu X,Yue J,Yang N,Zuo P

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Recent research suggests that 6% hydroxyethyl starch (HES) 130/0.4 is one of the most frequently used resuscitation fluids worldwide. The retraction of studies evaluating its use necessitates a reevaluation of available evidence regarding its safety and efficacy. METHODS:We performed a systematic review and...

journal_title：Anesthesia and analgesia

authors： Gattas DJ,Dan A,Myburgh J,Billot L,Lo S,Finfer S,CHEST Management Committee.

更新日期：2012-01-01 00:00:00