Reversal of central nervous system and cardiac toxicity after local anesthetic intoxication by lipid emulsion injection.

abstract：:Intraocular pressure (IOP) measurements in children are usually performed under nitrous oxide and halothane anesthesia. We studied the effects of both time and end-tidal halothane concentration on IOP in 80 children (mean age +/- SD = 4.5 +/- 2.9 yr), to determine the most optimal time to make such measurements in ane...

journal_title：Anesthesia and analgesia

authors： Watcha MF,Chu FC,Stevens JL,Forestner JE

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Even though current perception threshold (CPT) has been used for evaluating the effectiveness of sensory block in patients before surgery, its reliability under controlled conditions has not been investigated. Two independent investigations were performed. The primary objective of the first study was to dete...

journal_title：Anesthesia and analgesia

authors： Gaudreault F,Drolet P,Fallaha M,Varin F

更新日期：2015-03-01 00:00:00

abstract：:Cimetidine blunts the increase in cerebral blood flow (CBF) normally observed during hypoxia. It is important, therefore, to know whether other H2-blockers also affect the cerebral circulation adaptation to hypoxia. Cerebral blood flow was measured in 24 awake dogs after an intravenous injection of either saline (cont...

journal_title：Anesthesia and analgesia

authors： Audibert G,Saunier C,Hartemann D,Bigard O,Haberer JP

更新日期：1991-04-01 00:00:00

abstract：UNLABELLED:We compared, in a double-blinded manner, the anesthetic maintenance and recovery properties of remifentanil with a clinically comparable fentanyl-based anesthetic technique in pediatric ambulatory surgical patients. Anesthesia was induced with either halothane or sevoflurane and nitrous oxide and oxygen. Pat...

journal_title：Anesthesia and analgesia

authors： Davis PJ,Finkel JC,Orr RJ,Fazi L,Mulroy JJ,Woelfel SK,Hannallah RS,Lynn AM,Kurth CD,Moro M,Henson LG,Goodman DK,Decker MD

更新日期：2000-04-01 00:00:00

abstract：:Dantrolene effectively treats malignant hyperthermia (MH) hut the current form, Dantrium, must be dissolved to a 0.33 mg/mL, pH 9.5 solution. This study describes lecithin-coated microcrystal formulations of sodium dantrolene (MC-NaD) and neutral dantrolene (MC-D) which reconstitute to 200 mg/mL within 1 min. In rats,...

journal_title：Anesthesia and analgesia

authors： Karan SM,Lojeski EW,Haynes DH,Bina S,Wesche DL,Boedeker BH,Muldoon SM

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The cerebral perfusion pressure that denotes the lower limit of cerebral blood flow autoregulation (LLA) is generally considered to be equivalent for reductions in arterial blood pressure (ABP) or increases in intracranial pressure (ICP). However, the effect of decreasing ABP at different levels of ICP has n...

journal_title：Anesthesia and analgesia

authors： Brady KM,Lee JK,Kibler KK,Easley RB,Koehler RC,Czosnyka M,Smielewski P,Shaffner DH

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Local anesthetics cause reversible block of pain and robustly inhibit TWIK-related K channel (TREK-1) currents. Before local anesthesia onset, injection of local anesthetics can cause unwanted transient pain. TREK-1 is an anesthetic-sensitive potassium channel that when inhibited produces pain. A disordered ...

journal_title：Anesthesia and analgesia

authors： Pavel MA,Chung HW,Petersen EN,Hansen SB

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine, an α(2)-receptor agonist, prolongs analgesia when used in neuraxial and IV blocks. We evaluated the effect of dexmedetomidine added to ropivacaine for tibial nerve block on the duration of the sensory blockade. METHODS:For this prospective, randomized, controlled, double-blind, crossover tr...

journal_title：Anesthesia and analgesia

authors： Rancourt MP,Albert NT,Côté M,Létourneau DR,Bernard PM

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Unicondylar knee arthroplasty (UKA) is a commonly performed procedure with significant expected postoperative pain. Peripheral nerve blocks are 1 analgesic option, but some approaches may decrease quadriceps motor strength and interfere with early ambulation. In this study, we compared the analgesia provided...

journal_title：Anesthesia and analgesia

authors： Henshaw DS,Jaffe JD,Reynolds JW,Dobson S,Russell GB,Weller RS

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Unanticipated hospital admission is regarded as a measure of adverse perioperative patient care. However, previously published studies for risk prediction after ambulatory procedures are sparse compared to those examining readmission after inpatient surgery. We aimed to evaluate the incidence and reasons for...

journal_title：Anesthesia and analgesia

authors： Teja B,Raub D,Friedrich S,Rostin P,Patrocínio MD,Schneider JC,Shen C,Brat GA,Houle TT,Yeh RW,Eikermann M

更新日期：2020-08-01 00:00:00

abstract：:The renal effects of pulsatile (pulse pressure 18.0 +/- 1.5 mm Hg [mean +/- SEM]) or nonpulsatile perfusion (mean pulse pressure 1.9 +/- 0.4 mm Hg) during either alpha-stat (mean PaCO2 41.2 +/- 0.9 mm Hg measured at 37 degrees C) or pH-stat (mean PaCO2 60.6 +/- 1.7 mm Hg measured at 37 degrees C) pH management of hypo...

journal_title：Anesthesia and analgesia

authors： Badner NH,Murkin JM,Lok P

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Recombinant activated factor VII (rFVIIa) is increasingly used for treating refractory bleeding after cardiac surgery. However, hemostasis also depends on coagulation factors, including fibrinogen, which stabilizes platelet plugs at sites of vascular injury. We compared the hemostatic effects of rFVIIa, fibr...

journal_title：Anesthesia and analgesia

authors： Tanaka KA,Taketomi T,Szlam F,Calatzis A,Levy JH

更新日期：2008-03-01 00:00:00

abstract：:Seven anesthetized patients were studied to determine the interaction between pancuronium and lincomycin and the ability of neostigmine and 4-aminopyridine to antagonize the block. Lincomycin 600 mg given IV alone did not decrease twitch tension. An 8 to 10% decrease in twitch tension occurred when lincomycin was give...

journal_title：Anesthesia and analgesia

authors： Booij LH,Miller RD,Crul JF

更新日期：1978-05-01 00:00:00

abstract：:We studied the time to postoperative micturition and the duration of analgesia in 82 children aged 6 mo to 10 yr undergoing herniorrhaphy or orchiopexy under general anesthesia with N2O and halothane. All received D5 lactate Ringer's solution equivalent to 6 h maintenance intraoperatively, and oral fluids postoperativ...

journal_title：Anesthesia and analgesia

authors： Fisher QA,McComiskey CM,Hill JL,Spurrier EA,Voigt RE,Savarese AM,Beaver BL,Boltz MG

更新日期：1993-01-01 00:00:00

abstract：:Informed consent for pediatric anesthesia challenges practitioners to navigate complex ethical, medical, and legal ambiguities. A patient's status as a minor does not negate the importance of his or her participation in the decision-making process but, rather, necessitates a nuanced evaluation of age and development t...

journal_title：Anesthesia and analgesia

authors： Feinstein MM,Pannunzio AE,Lobell S,Kodish E

更新日期：2018-12-01 00:00:00

abstract：:This randomized double-blind study compared the hemodynamic and metabolic effects of pancuronium and vecuronium during treatment of shivering after cardiac surgery with hypothermic cardiopulmonary bypass. Thirty sedated and pain-free patients who shivered after cardiac surgery were treated with pancuronium (n = 15) or...

journal_title：Anesthesia and analgesia

authors： Dupuis JY,Nathan HJ,DeLima L,Wynands JE,Russell GN,Bourke M

更新日期：1994-09-01 00:00:00

abstract：:Recent determinations of the minimum alveolar anesthetic concentration (MAC) for nitrous oxide in rats yield values of 1.51-1.55 atm. When combined with results from other reports, these results suggest a deviation from linear additivity, and call into question the unitary theory of narcosis. The present report provid...

journal_title：Anesthesia and analgesia

authors： Gonsowski CT,Eger EI 2nd

更新日期：1994-10-01 00:00:00

abstract：:The effects of narcotic agents and two inhalation anesthetics on intrabiliary pressure (IBP) were measured before and after morphine (0.2 mg/kg), meperidine (2 mg/kg), fentanyl (0.002 mg/kg), or pentazocine (1 mg/kg) given intramuscularly to guinea pigs, and after halothane (0.5, 1.0, 1.5, or 2.0 MAC) or enflurane (sa...

journal_title：Anesthesia and analgesia

authors： Arguelles JE,Franatovic Y,Romo-Salas F,Aldrete JA

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:Although detailed analyses of the postmortem findings of various critically ill patient groups have been published, no such study has been performed in patients with sepsis. In this retrospective cohort study, we reviewed macroscopic postmortem examinations of surgical intensive care unit (ICU) patients who ...

journal_title：Anesthesia and analgesia

authors： Torgersen C,Moser P,Luckner G,Mayr V,Jochberger S,Hasibeder WR,Dünser MW

更新日期：2009-06-01 00:00:00

abstract：UNLABELLED:The purpose of this animal investigation was to compare behavioral responses with spinal Fos-like immunoreactivity (FLI) after pre-versus postformalin administration of anesthetic doses of IV ketamine or alfentanil. Preformalin and postformalin injection (1.5% subcutaneously) treatment groups included IV sal...

journal_title：Anesthesia and analgesia

authors： Gilron I,Quirion R,Coderre TJ

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Although invasive monitoring is the standard method for intracranial pressure (ICP) measurement, it is not without potential for serious complications. Noninvasive methods have been proposed as alternatives to invasive ICP monitoring. The study aimed to investigate the diagnostic accuracy of the currently av...

journal_title：Anesthesia and analgesia

authors： Sallam A,Abdelaal Ahmed Mahmoud M Alkhatip A,Kamel MG,Hamza MK,Yassin HM,Hosny H,Younis MI,Ramadan E,Algameel HZ,Abdelhaq M,Abdelkader M,Mills KE,Mohamed H

更新日期：2020-09-24 00:00:00

abstract：BACKGROUND:Many of the complications of mechanical ventilation are related to inappropriate endotracheal tube (ETT) cuff pressure. The aim of the current study was to evaluate the effectiveness of automatic cuff pressure closed-loop control in patients under prolonged intubation, where presence of carbon dioxide (CO2) ...

journal_title：Anesthesia and analgesia

authors： Efrati S,Bolotin G,Levi L,Zaaroor M,Guralnik L,Weksler N,Levinger U,Soroksky A,Denman WT,Gurman GM

更新日期：2017-10-01 00:00:00

abstract：UNLABELLED:Incorrect positioning of central venous catheters (CVC) in infants and children may lead to serious complications such as perforation of the heart or great vessels. CVC position is not usually assessed until the first postoperative chest radiograph, potentially leaving malposition undetected for several hour...

journal_title：Anesthesia and analgesia

authors： Andropoulos DB,Bent ST,Skjonsby B,Stayer SA

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:A potential physicochemical interaction between epidural local anesthetics and extended-release epidural morphine (EREM) could negate the sustained release. In this study, we sought to determine the pharmacokinetic and drug effects of prior epidural lidocaine administration on EREM. METHODS:Thirty healthy w...

journal_title：Anesthesia and analgesia

authors： Atkinson Ralls L,Drover DR,Clavijo CF,Carvalho B

更新日期：2011-08-01 00:00:00

abstract：UNLABELLED:The optimal dose and timing of 5-HT(3) antagonist administration for prophylaxis against postoperative nausea and vomiting (PONV) remains controversial. Although 5-HT(3) antagonists seem to be most effective when administered near the end of surgery, there are no data on the comparative efficacy or costs ass...

journal_title：Anesthesia and analgesia

authors： Zarate E,Watcha MF,White PF,Klein KW,Sa Rego M,Stewart DG

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Transcutaneous vagus nerve stimulation (TVNS) is a promising treatment for acute and chronic pain. However, experimental studies yielded controversial results. We examined if TVNS reduces the perceived intensity of repetitive painful heat stimulation and temporal summation of pain (TSP) in healthy volunteers...

journal_title：Anesthesia and analgesia

authors： Janner H,Klausenitz C,Gürtler N,Hahnenkamp K,Usichenko TI

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Predicting blood product transfusion requirements during orthotopic liver transplantation (OLT) remains difficult. Our primary aim in this study was to determine which patient variables best predict recipient risk for large blood transfusion requirements during OLT. The secondary aim was to determine whether...

journal_title：Anesthesia and analgesia

authors： Cywinski JB,Alster JM,Miller C,Vogt DP,Parker BM

更新日期：2014-02-01 00:00:00

abstract：UNLABELLED:As medical costs continue to escalate, there is willingness to consider the role played by nontraditional factors in health. We investigated the usefulness of tape-recorded hypnosis instruction on perioperative outcome in surgical patients in a prospective, randomized, and partially blinded study. Sixty pati...

journal_title：Anesthesia and analgesia

authors： Ghoneim MM,Block RI,Sarasin DS,Davis CS,Marchman JN

更新日期：2000-01-01 00:00:00

abstract：:A previous demonstration that the ratio of analgesic to anesthetic endpoints is not constant across inhalation anesthetic agents implies that more than one mechanism of action may be operant in general anesthesia. We hypothesized that the endogenous opiate systems might account for this observed disparity in ratios. T...

journal_title：Anesthesia and analgesia

authors： Levine LL,Winter PM,Nemoto EM,Uram M,Lin MR

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a "lighter" depth of sedation. Among these strategies are "analgosedation" protocols, which prioritize pain management and preferentially use IV opioids before administration of continuously...

journal_title：Anesthesia and analgesia

authors： Faust AC,Rajan P,Sheperd LA,Alvarez CA,McCorstin P,Doebele RL

更新日期：2016-10-01 00:00:00