The frequency and magnitude of cerebrospinal fluid pulsations influence intrathecal drug distribution: key factors for interpatient variability.

abstract：UNLABELLED:Perturbation of respiratory mechanics produced by general anesthesia and surgery is more pronounced in morbidly obese (MO) patients. Because general anesthesia induces pulmonary atelectasis in nonobese patients, we hypothesized that atelectasis formation would be particularly significant in MO patients. We i...

journal_title：Anesthesia and analgesia

authors： Eichenberger A,Proietti S,Wicky S,Frascarolo P,Suter M,Spahn DR,Magnusson L

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Spinal cord monitoring is associated with a significantly lower rate of neurologic deficits after deformity surgery, and has been shown to have predictive value in cervical, thoracic, and lumbar surgery. Lower extremity motor evoked potentials (MEPs) are particularly sensitive to anesthetics and physiologic ...

journal_title：Anesthesia and analgesia

authors： Deiner SG,Kwatra SG,Lin HM,Weisz DJ

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Blood hemoglobin can be monitored continuously and noninvasively with a noninvasive spectrophotometric sensor (Masimo SpHb). The perfusion index (PI) of the finger is directly related to the clinical accuracy of SpHb. We evaluated those variables that influence PI without the influences of surgery and anesth...

journal_title：Anesthesia and analgesia

authors： Miller RD,Ward TA,McCulloch CE,Cohen NH

更新日期：2014-04-01 00:00:00

abstract：UNLABELLED:The finger plethysmographic waveform of pulse oximeters is a qualitative indicator of fingertip perfusion. This waveform has been used to assess the depth of anesthesia. Its cyclical changes associated with mechanical ventilation have also been used to detect changes in blood volume under normotensive condit...

journal_title：Anesthesia and analgesia

authors： Golparvar M,Naddafnia H,Saghaei M

更新日期：2002-12-01 00:00:00

abstract：:The purpose of this study was to examine the effects of alfentanil applied to the surface of the spinal cord and the effects of intravenously administered alfentanil on noxiously evoked activity of dorsal horn neurons. Extracellular single neuron recordings were obtained from wide dynamic range neurons in 26 decerebra...

journal_title：Anesthesia and analgesia

authors： Matsumoto M,Collins JG,Kitahata LM,Yuge O,Tanaka A

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:There are three basic types of decision aids to facilitate operating room (OR) management decision-making on the day of surgery. Decision makers can rely on passive status displays (e.g., big screens or whiteboards), active status displays (e.g., text pager notification), and/or command displays (e.g., text ...

journal_title：Anesthesia and analgesia

authors： Dexter F,Willemsen-Dunlap A,Lee JD

更新日期：2007-08-01 00:00:00

abstract：:The insertion of implantable cardioverter/defibrillators (ICD) requires induction of repeated episodes of ventricular fibrillation (VF). The neuropsychological repercussions associated with repeated inducement of hypotension and cerebral ischemia are unknown. In this prospective clinical trial, 1 day prior to ICD asse...

journal_title：Anesthesia and analgesia

authors： Murkin JM,Baird DL,Martzke JS,Yee R

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Cerebral cholinergic transmission plays a key role in cognitive function, and anticholinergic drugs administered during the perioperative phase are a hypothetical cause of postoperative cognitive dysfunction (POCD). We hypothesized that a perioperative increase in serum anticholinergic activity (SAA) is asso...

journal_title：Anesthesia and analgesia

authors： Rossi A,Burkhart C,Dell-Kuster S,Pollock BG,Strebel SP,Monsch AU,Kern C,Steiner LA

更新日期：2014-10-01 00:00:00

abstract：:A newly developed transtracheal Doppler (TTD) computer for cardiac output determination was studied in nine patients after open heart surgery (coronary artery bypass grafting, n = 4; mitral valve replacement, n = 5). The measurements were compared with those simultaneously obtained by thermodilation. Doppler signals w...

journal_title：Anesthesia and analgesia

authors： Hausen B,Schäfers HJ,Rohde R,Haverich A

更新日期：1992-06-01 00:00:00

abstract：:The effects of volatile anesthetics on arterial mechanical properties in vivo are incompletely understood. The present investigation tested the hypothesis that isoflurane and halothane cause differential actions on the mechanical characteristics of the aorta in barbiturate-anesthetized dogs instrumented for measuremen...

journal_title：Anesthesia and analgesia

authors： Hettrick DA,Pagel PS,Warltier DC

更新日期：1996-12-01 00:00:00

abstract：:The effects of enflurane and halothane anesthesia on systolic time intervals were studied in 12 healthy patients. Cardiovascular measurements were made at equipotent levels of anesthesia: enflurane 1.23% end-tidal and halothane 0.65% end-tidal. These agents were studied first with 50% N2O and then without N2O. Systoli...

journal_title：Anesthesia and analgesia

authors： Kaplan JA,Miller ED,Bailey DR

更新日期：1976-03-01 00:00:00

abstract：:Several observational and objective methods are available to assess sedation depth; however, data regarding their accuracy in differentiating deep sedation are limited. In this study we compared 3 sedation tools in children from birth to 18 yr of age and determined their relative value in detecting deep levels of seda...

journal_title：Anesthesia and analgesia

authors： Malviya S,Voepel-Lewis T,Tait AR

更新日期：2006-02-01 00:00:00

abstract：UNLABELLED:Calcium-sensitizing drugs, such as levosimendan, are a novel class of drug therapy for heart failure. We investigated the hypothesis that levosimendan is a pulmonary vasodepressor mediated through inhibition of phosphodiesterase, adenosine triphosphate (ATP)-dependent potassium channels, or both. We investig...

journal_title：Anesthesia and analgesia

authors： De Witt BJ,Ibrahim IN,Bayer E,Fields AM,Richards TA,Banister RE,Kaye AD

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Although detailed analyses of the postmortem findings of various critically ill patient groups have been published, no such study has been performed in patients with sepsis. In this retrospective cohort study, we reviewed macroscopic postmortem examinations of surgical intensive care unit (ICU) patients who ...

journal_title：Anesthesia and analgesia

authors： Torgersen C,Moser P,Luckner G,Mayr V,Jochberger S,Hasibeder WR,Dünser MW

更新日期：2009-06-01 00:00:00

abstract：UNLABELLED:Natural killer (NK) cells can lyse certain tumor cells as well as virally infected cells without prior sensitization. Animal studies have shown that general anesthesia (GA) alone or GA followed by surgery decreases both basal NK cytotoxicity and enhancement of NK activity by interferon (IFN). The purpose of ...

journal_title：Anesthesia and analgesia

authors： Kutza J,Gratz I,Afshar M,Murasko DM

更新日期：1997-10-01 00:00:00

abstract：UNLABELLED:Besides having important hormonal effects, progesterone has depressant and hypnotic effects on the brain. In this study, we compared women in the follicular phase with low progesterone levels and in the luteal phase with high progesterone levels regarding their anesthetic requirements. Twenty patients with m...

journal_title：Anesthesia and analgesia

authors： Erden V,Yangin Z,Erkalp K,Delatioğlu H,Bahçeci F,Seyhan A

更新日期：2005-10-01 00:00:00

abstract：:To determine the pharmacokinetics of local anesthetics after lumbar sympathetic blocks, total and free (unbound) plasma concentrations of bupivacaine in venous blood samples were measured in 12 patients using a high-performance liquid chromatography (HPLC) technique. Administration of 30 mL of plain bupivacaine 0.175%...

journal_title：Anesthesia and analgesia

authors： Wulf H,Gleim M,Schele HA

更新日期：1994-11-01 00:00:00

abstract：UNLABELLED:The adenosine triphosphate (ATP)-sensitive potassium channels (K(+)-ATP channels) are activated by decreases in intracellular ATP and help to match blood flow to tissue needs. Such metabolism-flow coupling occurs predominantly in the smallest arterioles measuring 50 microm or less in diameter. Previous studi...

journal_title：Anesthesia and analgesia

authors： Park KW,Dai HB,Comunale ME,Gopal A,Sellke FW

更新日期：2000-07-01 00:00:00

abstract：:Isoproterenol 5 micrograms may be an effective marker of accidental intravascular injection in women in labor; however, before isoproterenol can be incorporated in routinely used epidural test doses, the safety and usefulness should be determined in an animal model. This study was designed to examine the hemodynamic e...

journal_title：Anesthesia and analgesia

authors： Marcus MA,Vertommen JD,Van Aken H,Wouters PF

更新日期：1996-05-01 00:00:00

abstract：:The rate of hydrolysis of chloroprocaine by human serum was studied in the presence and absence of a number of aminde local anesthetics and their metabolites. Bupivacaine (2.4 microgram/ml) and etidocaine (2.3 microgram/ml) caused 38% and 21% inhibition respectively of the rate of chloroprocaine hydrolysis. Circulatin...

journal_title：Anesthesia and analgesia

authors： Lalka D,Vicuna N,Burrow SR,Jones DJ,Ludden TM,Haegele KD,McNay JL

更新日期：1978-09-01 00:00:00

abstract：UNLABELLED:Although isoflurane is a known vasodilator, the mechanism of isoflurane-induced vasodilation is not clear. One of the most important systems in this context is the nitric oxide (NO)-mediated vasodilation. The activity of this system is regulated by the agonist-induced Ca(2+) influx rather than Ca(2+) release...

journal_title：Anesthesia and analgesia

authors： Tas PW,Stöbetael C,Roewer N

更新日期：2003-08-01 00:00:00

abstract：:Early tracheal extubation has been safely performed after large operative procedures, questioning the need for routine postoperative ventilation. Because immediate postoperative tracheal extubation of liver transplantation patients has not been previously reported, we performed preliminary studies at two institutions ...

journal_title：Anesthesia and analgesia

authors： Mandell MS,Lockrem J,Kelley SD

更新日期：1997-02-01 00:00:00

abstract：UNLABELLED:IV volume is often administered to patients in an intensive care unit (ICU) to improve cardiovascular function. We investigated the relationship between stroke volume (SV) and left ventricular (LV) size by using transesophageal echocardiography (TEE) in a population of 20 ICU patients and 21 postoperative ca...

journal_title：Anesthesia and analgesia

authors： Tousignant CP,Walsh F,Mazer CD

更新日期：2000-02-01 00:00:00

abstract：:The Bonfils Retromolar Intubation Fiberscope is a rigid, straight fiberoptic device with a 40-degree curved tip, which facilitates targeted intubation. Bonfils, using a retromolar approach to intubate tracheas of children with Pierre Robin syndrome, was first described in 1983. After an initial steep learning curve, t...

journal_title：Anesthesia and analgesia

authors： Thong SY,Wong TG

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:With health care practice consolidation, the increasing geographic scope of health care systems, and the advancement of mobile telecommunications, there is increasing interest in telemedicine-based health care consultations. Anesthesiology has had experience with telemedicine consultation for preoperative ev...

journal_title：Anesthesia and analgesia

authors： Kamdar NV,Huverserian A,Jalilian L,Thi W,Duval V,Beck L,Brooker L,Grogan T,Lin A,Cannesson M

更新日期：2020-12-01 00:00:00

abstract：:Complement activation and the resulting inflammatory response is an important potential mechanism for multisystem organ injury in cardiac surgery. Novel therapeutic strategies using complement inhibitors may hold promise for improving outcomes for cardiac surgical patients by attenuating complement activation or its b...

journal_title：Anesthesia and analgesia

authors： Stahl GL,Shernan SK,Smith PK,Levy JH

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that MAC for isoflurane directly correlates with the concentration of Na(+) in cerebrospinal fluid surrounding the spinal cord, the primary site for mediation of the immobility produced by inhaled anesthetics. If this correlation resulted from increased irritability of the cord,...

journal_title：Anesthesia and analgesia

authors： Shnayderman D,Laster MJ,Eger EI 2nd,Oh I,Zhang Y,Jinks SL,Antognini JF,Raines DE

更新日期：2008-09-01 00:00:00

abstract：:The assessment of sympathetic denervation to the upper extremities during surgery for hyperhidrosis is essential in predicting postoperative outcome, particularly for endoscopic thoracic chain sympathotomy, a recently described, minimally destructive technique that minimizes postoperative compensatory hyperhidrosis. T...

journal_title：Anesthesia and analgesia

authors： Eisenach JH,Pike TL,Wick DE,Dietz NM,Fealey RD,Atkinson JL,Charkoudian N

更新日期：2005-01-01 00:00:00

abstract：:Over the last decade, there has been a heightened awareness and an increase in the amount of literature being published on recognition and prediction of the difficult airway. During the preoperative evaluation of the airway, a thorough history and physical specifically related to the airway should be performed. Variou...

journal_title：Anesthesia and analgesia

authors： Cattano D,Panicucci E,Paolicchi A,Forfori F,Giunta F,Hagberg C

更新日期：2004-12-01 00:00:00

abstract：:The development of a technique for studying spinal dorsal horn electrophysiology in intact, awake, drug-free cats enables the study of spinal sites and mechanisms of action of anesthetic and analgesic agents in a system that more closely reflects normal physiology. Using this technique, we reevaluated the effect of ke...

journal_title：Anesthesia and analgesia

authors： Collins JG

更新日期：1986-11-01 00:00:00