Intrathecal injection of the peptide myr-NR2B9c attenuates bone cancer pain via perturbing N-methyl-D-aspartate receptor-PSD-95 protein interactions in mice.

abstract：BACKGROUND:Anesthesiologists and certified registered nurse anesthetists (CRNAs) must acquire the skills to recognize and manage a variety of acute intraoperative emergencies. A simulation-based assessment provides a useful and efficient means to evaluate these skills. In this study, we evaluated and compared the perfo...

journal_title：Anesthesia and analgesia

authors： Henrichs BM,Avidan MS,Murray DJ,Boulet JR,Kras J,Krause B,Snider R,Evers AS

更新日期：2009-01-01 00:00:00

abstract：:Few anesthesia studies have explored perioperative continuous epidural infusion of neostigmine. We examined such a regimen in thoracotomy patients. Ninety patients were randomized to one of three groups in this double-blind trial. Before anesthesia induction, an epidural catheter was inserted in all patients at T5-8 l...

journal_title：Anesthesia and analgesia

authors： Chia YY,Chang TH,Liu K,Chang HC,Ko NH,Wang YM

更新日期：2006-01-01 00:00:00

abstract：:To determine whether nalbuphine might replace fentanyl as the principal opioid for anesthesia during coronary artery bypass surgery, 20 patients undergoing myocardial revascularization were anesthetized with flunitrazepam and with a continuous infusion of either nalbuphine (an opioid agonist-antagonist) or fentanyl (a...

journal_title：Anesthesia and analgesia

authors： Weiss BM,Schmid ER,Gattiker RI

更新日期：1991-11-01 00:00:00

abstract：:Hepatic blood flow and the oxygen supply/uptake relation were studied in 19 miniature pigs using labeled microspheres. Changes in hepatic arterial blood flow and portal blood flow, as well as total hepatic blood flow during halothane anesthesia were more closely associated with changes in mean arterial pressure (MAP) ...

journal_title：Anesthesia and analgesia

authors： Gelman S,Dillard E,Bradley EL Jr

更新日期：1987-10-01 00:00:00

abstract：UNLABELLED:We sought to determine minimum alveolar anesthetic concentrations for skin incision (MAC) and for tracheal extubation (MAC(Ex)) for sevoflurane and its associated awakening time and respiratory complications during emergence from sevoflurane anesthesia in children. We studied 40 (20 in each group) unpremedic...

journal_title：Anesthesia and analgesia

authors： Inomata S,Suwa T,Toyooka H,Suto Y

更新日期：1998-12-01 00:00:00

abstract：UNLABELLED:Labor epidural analgesia (LEA) is allegedly associated with maternal fever and an increase in the newborn sepsis work-up (SWU) rate. In this study, we evaluated whether LEA causes an increase in the SWU rate compared with a Control group given parenteral narcotics for labor pain. Maternal and neonatal data w...

journal_title：Anesthesia and analgesia

authors： Kaul B,Vallejo M,Ramanathan S,Mandell G

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Anesthesia care has been provided by diverse health professionals worldwide, but little is known about anesthesiologists' views about this. Using a survey, we sought the opinions of a group of Brazilian anesthesiologists regarding nitrous oxide/oxygen and oral minimal/moderate sedation performed by dentists....

journal_title：Anesthesia and analgesia

authors： Costa PS,Valadao WJ Jr,Costa LR

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Percutaneous cannulation of the femoral vein, in the pediatric age group, can be technically challenging, especially when performed by residents in training. We examined whether the use of real-time ultrasound guidance is superior to a landmark technique for femoral vein catheterization in children undergoin...

journal_title：Anesthesia and analgesia

authors： Aouad MT,Kanazi GE,Abdallah FW,Moukaddem FH,Turbay MJ,Obeid MY,Siddik-Sayyid SM

更新日期：2010-09-01 00:00:00

abstract：UNLABELLED:A cohort of seven patients receiving intrathecal analgesic drug therapy for chronic intractable pain underwent radiocontrast myelography and computed tomography (CT) scanning to screen for catheter-associated intrathecal masses. Three of seven patients examined had intraspinal masses associated with the tip ...

journal_title：Anesthesia and analgesia

authors： McMillan MR,Doud T,Nugent W

更新日期：2003-01-01 00:00:00

abstract：:Initial, but not subsequent, inhalation of 8% desflurane produces transient sympathetic stimulation. We hypothesized that initial but not subsequent increases should produce pupil dilation, and that N2O, fentanyl, and clonidine, but not esmolol, should blunt the response. In 10 volunteers, we maintained anesthesia wit...

journal_title：Anesthesia and analgesia

authors： Daniel M,Larson MD,Eger EI 2nd,Noorani M,Weiskopf RB

更新日期：1995-08-01 00:00:00

abstract：:Reactive oxygen species (ROS) are central to cardiac ischemic and reperfusion injury. They contribute to myocardial stunning, infarction and apoptosis, and possibly to the genesis of arrhythmias. Multiple laboratory studies and clinical trials have evaluated the use of scavengers of ROS to protect the heart from the e...

journal_title：Anesthesia and analgesia

authors： Kevin LG,Novalija E,Stowe DF

更新日期：2005-11-01 00:00:00

abstract：:The aim of the present study was to investigate the impact of isoflurane on regional neurogenic mechanisms in the control of vascular tone. Therefore, regional determinations of sympathetic activity and hemodynamics were made in chloralose-anesthetized swine before and during administration of 1.4% isoflurane. Sympath...

journal_title：Anesthesia and analgesia

authors： Aneman A,Pontén J,Fändriks L,Eisenhofer G,Friberg P,Biber B

更新日期：1995-01-01 00:00:00

abstract：UNLABELLED:There are situations in anesthesia in which it may be desirable to achieve rapid tracheal intubation with perfect conditions, i.e., no coughing or straining. To determine the dose of rocuronium that gives a high probability of achieving perfect conditions for rapid (within 60 s) tracheal intubation, we admin...

journal_title：Anesthesia and analgesia

authors： Heier T,Caldwell JE

更新日期：2000-01-01 00:00:00

abstract：UNLABELLED:We evaluated the pretreatment of small-dose of ketamine or normal saline in the reduction of withdrawal movements induced by rocuronium injection. One-hundred pediatric patients (aged 1-6 yr) were randomly assigned into 2 groups. A 22-gauge IV cannula was inserted into the dorsum of the hand, and ketamine 0....

journal_title：Anesthesia and analgesia

authors： Liou JT,Hsu JC,Liu FC,Ching-Wah Sum D,Lui PW

更新日期：2003-11-01 00:00:00

abstract：:Ultrasound has become a widely used tool within the practice of regional anesthesia, offering real-time visualization of the nerves, needle, and local anesthetic during performance of a block. A successful ultrasound-guided axillary block was performed on a healthy adult male undergoing wrist surgery. Postoperative re...

journal_title：Anesthesia and analgesia

authors： Russon K,Blanco R

更新日期：2007-11-01 00:00:00

abstract：:We were interested in determining the effect of enflurane, halothane, and isoflurane on the uptake and removal of 5-hydroxytryptamine (5-HT) and phenylethylamine (PEA) from the lung. Isolated rabbit lungs were perfused in a recirculating system in vitro with 0.1 microM [14C]5-HT or 0.1 microM [14C]PEA in Krebs-Ringer ...

journal_title：Anesthesia and analgesia

authors： Cook DR,Brandom BW

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:Drugs such as propofol and ketamine are used alone or in combination to provide sedation for medical procedures in children. The purpose of this systematic review was to compare the safety and effectiveness of propofol and ketamine to other drug regimens. METHODS:We searched Medline, Embase, Cochrane Centra...

journal_title：Anesthesia and analgesia

authors： Hayes JA,Aljuhani T,De Oliveira K,Johnston BC

更新日期：2020-07-07 00:00:00

abstract：:We studied the effect of large-dose intrathecal sufentanil (ITS) for major abdominal surgery on the hormonal stress response. Forty patients were randomly allocated to receive either IV sufentanil (IVS) or 150 microg of ITS as part of general anesthesia. In the IVS group, adrenocorticotropic hormone (ACTH) and cortiso...

journal_title：Anesthesia and analgesia

authors： Borgdorff PJ,Ionescu TI,Houweling PL,Knape JT

更新日期：2004-10-01 00:00:00

abstract：:Prothrombin complex concentrates (PCCs) contain vitamin K-dependent clotting factors (II, VII, IX, and X) and are marketed as 3 or 4 factor-PCC formulations depending on the concentrations of factor VII. PCCs rapidly restore deficient coagulation factor concentrations to achieve hemostasis, but like with all procoagul...

journal_title：Anesthesia and analgesia

authors： Ghadimi K,Levy JH,Welsby IJ

更新日期：2016-05-01 00:00:00

abstract：:In the perioperative period, artificial colloids are most often infused in doses of 500-1000 mL intravenously. This randomized study compared the effects on intravascular volume and coagulation of approximately 2000 mL of two isooncotic artificial colloids: 6% hydroxyethyl starch (HES; MW 200,000; substitution ratio 0...

journal_title：Anesthesia and analgesia

authors： Mortelmans YJ,Vermaut G,Verbruggen AM,Arnout JM,Vermylen J,Van Aken H,Mortelmans LA

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Anesthesia induction in children is frequently achieved by inhalation of nitrous oxide and sevoflurane. Pediatric anesthesiologists commonly use distraction techniques such as humor or nonprocedural talk to reduce anxiety and facilitate a smooth transition at this critical phase. There is a large body of suc...

journal_title：Anesthesia and analgesia

authors： Mifflin KA,Hackmann T,Chorney JM

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Unanticipated hospital admission is regarded as a measure of adverse perioperative patient care. However, previously published studies for risk prediction after ambulatory procedures are sparse compared to those examining readmission after inpatient surgery. We aimed to evaluate the incidence and reasons for...

journal_title：Anesthesia and analgesia

authors： Teja B,Raub D,Friedrich S,Rostin P,Patrocínio MD,Schneider JC,Shen C,Brat GA,Houle TT,Yeh RW,Eikermann M

更新日期：2020-08-01 00:00:00

abstract：:During Gram-negative sepsis, endotoxin lipopolysaccharide (LPS) may activate host inflammatory responses, resulting in the systemic inflammatory response syndrome and the adult respiratory distress syndrome. In cell culture systems, LPS activation of cellular responses may be potentiated by plasma proteins. In the iso...

journal_title：Anesthesia and analgesia

authors： Goldsmith JA,Kavanagh BP,Pearl RG

更新日期：1996-08-01 00:00:00

abstract：UNLABELLED:We examined how to program an operating room (OR) information system to assist the OR manager in deciding whether to move the last case of the day in one OR to another OR that is empty to decrease overtime labor costs. We first developed a statistical strategy to predict whether moving the case would decreas...

journal_title：Anesthesia and analgesia

authors： Dexter F

更新日期：2000-10-01 00:00:00

abstract：UNLABELLED:Natural killer (NK) cells can lyse certain tumor cells as well as virally infected cells without prior sensitization. Animal studies have shown that general anesthesia (GA) alone or GA followed by surgery decreases both basal NK cytotoxicity and enhancement of NK activity by interferon (IFN). The purpose of ...

journal_title：Anesthesia and analgesia

authors： Kutza J,Gratz I,Afshar M,Murasko DM

更新日期：1997-10-01 00:00:00

abstract：:Twenty-four male patients scheduled for elective pulmonary resection were studied to determine whether continuous insufflation of oxygen to the nonventilated lung would reduce intrapulmonary shunting (Qs/Qt) and arterial oxygen desaturation. Measurements of physiologic variables were made using pulmonary arterial and ...

journal_title：Anesthesia and analgesia

authors： Rees DI,Wansbrough SR

更新日期：1982-06-01 00:00:00

abstract：:The aim of this study was to correlate pupillary diameter with respiratory depression for 20 hr after epidural administration of morphine or buprenorphine. Pupillary diameter and the ventilatory sensitivity to CO2 were measured in six healthy volunteers at various times (0, 0.5, 1, 2, 3, 4, 6, 8, 10, 12, and 20 hr) in...

journal_title：Anesthesia and analgesia

authors： Ravnborg M,Jensen FM,Jensen NH,Holk IK

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Patients with bone marrow failure and severe thrombocytopenia are frequently given prophylactic platelet transfusion before interventions. The clinical effects of such transfusions, however, are poorly defined. We performed a prospective observational study on patients with bone marrow failure scheduled for ...

journal_title：Anesthesia and analgesia

authors： Kander T,Tanaka KA,Norström E,Persson J,Schött U

更新日期：2014-10-01 00:00:00

abstract：:Bispectral Index Scale (BIS)-guided closed-loop delivery of anesthetics has been extensively studied. We performed a meta-analysis of all the randomized clinical trials comparing efficacy and performance between BIS-guided closed-loop delivery and manually controlled administration of total IV anesthesia. Scopus, PubM...

journal_title：Anesthesia and analgesia

authors： Pasin L,Nardelli P,Pintaudi M,Greco M,Zambon M,Cabrini L,Zangrillo A

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Oral opioid formulations contribute to postoperative analgesia. In this study, we evaluated the perioperative application of oral controlled-release oxycodone to reduce postoperative IV morphine consumption and opioid side effects after lumbar discectomy. METHODS:Forty patients scheduled for elective lumbar...

journal_title：Anesthesia and analgesia

authors： Blumenthal S,Min K,Marquardt M,Borgeat A

更新日期：2007-07-01 00:00:00