Blood use in patients undergoing coronary artery bypass surgery: impact of cardiopulmonary bypass pump, hematocrit, gender, age, and body weight.


UNLABELLED:We investigated the impact of cardiopulmonary bypass pump (CPB), hematocrit, gender, age, and body weight on blood use in patients undergoing coronary artery bypass graft surgery at a major university hospital. Participants were 1235 consecutive patients undergoing primary coronary artery surgery over a period of 2 yr (1999 and 2000); 681 patients underwent coronary surgery with use of CPB, and 554 patients underwent off-pump coronary artery bypass surgery using a median sternotomy incision. There were 881 males and 354 females. Average packed red blood cells (PRBC) transfusion for patients on CPB was 3.4 U compared with 1.6 U for the off-pump group (P = <0.001). Patients on CPB received more frequent PRBC transfusion (72.5%) compared with 45.7% of off-pump patients (P = <0.001). Average PRBC transfusion for males was 2.2 U compared with 3.6 U for females (P = <0.001). A lower percentage of males (52.6%) than females (79.4%) received transfusion (P = <0.001). The impact of CPB, off-pump status, preoperative hematocrit <35%, gender, age >or=65 yr, and weight


Anesth Analg


Anesthesia and analgesia


Scott BH,Seifert FC,Glass PS,Grimson R




Has Abstract


2003-10-01 00:00:00


958-63, table of contents










  • The safety and effectiveness of remifentanil as an adjunct sedative for regional anesthesia.

    abstract:UNLABELLED:We assessed the sedative potential of continuous infusions of remifentanil with a validated composite alertness scale in 160 patients (ASA physical status I or II) undergoing hip replacement surgery with spinal block (n = 61) or hand surgery using brachial plexus block (n = 93). They were randomized to recei...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Lauwers M,Camu F,Breivik H,Hagelberg A,Rosen M,Sneyd R,Horn A,Noronha D,Shaikh S

    更新日期:1999-01-01 00:00:00

  • Preoperative local infiltration with ropivacaine for postoperative pain relief after cholecystectomy.

    abstract::In a randomized, double-blind, placebo-controlled trial, we evaluated the use of preoperative local anesthesia with regard to postoperative pain. Before surgery in 66 patients scheduled for cholecystectomy, the abdominal wall along the proposed line of incision was infiltrated with 70 mL of 0.25% ropivacaine, 70 mL of...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Johansson B,Glise H,Hallerbäck B,Dalman P,Kristoffersson A

    更新日期:1994-02-01 00:00:00

  • Determining minimum alveolar anesthetic concentration of halothane in rats: the effect of incremental change in halothane concentration and number of crossovers.

    abstract::Computer simulations for the technique of estimating minimum alveolar anesthetic concentration (MAC) in patients (quantal design) suggest that incremental concentration changes and the number of crossovers affect MAC. We hypothesized that these variables may also apply to estimating MAC in rats (bracketing design). Th...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Leon A,Mayzler O,Benifla M,Semionov M,Fuxman Y,Eilig I,Passuga V,Doitchinova MK,Gurevich B,Artru AA,Shapira Y

    更新日期:2004-12-01 00:00:00

  • Assessing cognitive and psychomotor performance under long-term treatment with transdermal buprenorphine in chronic noncancer pain patients.

    abstract:BACKGROUND:The therapeutic use of opioids has been associated with altered cognition and impaired psychomotor function. Several studies have demonstrated the impact of opioid therapy on psychomotor performance and cognition, but there are no data about the effect of long-term treatment with transdermal buprenorphine on...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Dagtekin O,Gerbershagen HJ,Wagner W,Petzke F,Radbruch L,Sabatowski R

    更新日期:2007-11-01 00:00:00

  • Immunoreactive substance P is decreased in saliva of patients with chronic back pain syndromes.

    abstract::Substance P, a neuropeptide associated with pain perception, is widely distributed in the central nervous system and is decreased in the cerebrospinal fluid of chronic pain patients as compared with that of healthy human volunteers. In this study, we have demonstrated the presence of immunoreactive substance P in sali...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Parris WC,Kambam JR,Naukam RJ,Rama Sastry BV

    更新日期:1990-01-01 00:00:00

  • The effect of GP683, an adenosine kinase inhibitor, on the desflurane anesthetic requirement in dogs.

    abstract:UNLABELLED:The availability of an analgesic compound devoid of the side effects associated with the commonly used opioid and nonsteroidal antiinflammatory drugs would be useful during the perioperative period. Although adenosine has analgesic and anesthetic-sparing properties, it also produces dose-dependent cardiovasc...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Wang B,Tang J,White PF,Foster AC,Grettenberger HM,Kopcho J,Wender RH

    更新日期:1997-09-01 00:00:00

  • Effect of Sevoflurane Versus Isoflurane on Emergence Time and Postanesthesia Care Unit Length of Stay: An Alternating Intervention Trial.

    abstract:BACKGROUND:We previously reported that the duration of hospitalization was not different between isoflurane and sevoflurane. But more plausible consequences of using soluble volatile anesthetics are delayed emergence from anesthesia and prolonged stays in the postanesthesia care unit (PACU). We therefore compared isofl...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章


    authors: Maheshwari K,Ahuja S,Mascha EJ,Cummings KC 3rd,Chahar P,Elsharkawy H,Kurz A,Turan A,Sessler DI

    更新日期:2020-02-01 00:00:00

  • Performance of certified registered nurse anesthetists and anesthesiologists in a simulation-based skills assessment.

    abstract:BACKGROUND:Anesthesiologists and certified registered nurse anesthetists (CRNAs) must acquire the skills to recognize and manage a variety of acute intraoperative emergencies. A simulation-based assessment provides a useful and efficient means to evaluate these skills. In this study, we evaluated and compared the perfo...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验


    authors: Henrichs BM,Avidan MS,Murray DJ,Boulet JR,Kras J,Krause B,Snider R,Evers AS

    更新日期:2009-01-01 00:00:00

  • Pressure-heart rate relationship in intact and after stepwise elimination of three major baroreflex loops in dogs.

    abstract::Systemic arterial blood pressure (BP)-heart rate (HR) relationship (the pressor test) is often used as an index of baroreflex. We evaluated this index by simultaneously comparing BP-HR, right carotid sinus pressure (CSP)-nerve action potentials (NAP), and NAP-HR relationship in dogs anesthetized with pentobarbital. BP...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Behnia R,Koushanpour E,Sinclair DM

    更新日期:1996-11-01 00:00:00

  • An in situ technique to retrieve an entrapped j-tip guidewire from an inferior vena cava filter.

    abstract:IMPLICATIONS:Entrapment of a guidewire in the vena cava filter during central venous catheter placement is a newly recognized complication. Complex techniques have been described to free the guidewire. We describe a simple in situ technique that may free the guidewire without the application of complex techniques. ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Munir MA,Chien SQ

    更新日期:2002-08-01 00:00:00

  • The ability of stroke volume variations obtained with Vigileo/FloTrac system to monitor fluid responsiveness in mechanically ventilated patients.

    abstract:BACKGROUND:Respiratory variations in arterial pulse pressure (DeltaPP) are accurate predictors of fluid responsiveness in mechanically ventilated patients. The aim of our study was to assess the ability of a novel algorithm for automatic estimation of stroke volume variation (SVV) to predict fluid responsiveness in mec...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Cannesson M,Musard H,Desebbe O,Boucau C,Simon R,Hénaine R,Lehot JJ

    更新日期:2009-02-01 00:00:00

  • The Analgesic Effect of Ultrasound-Guided Quadratus Lumborum Block After Cesarean Delivery: A Randomized Clinical Trial.

    abstract:BACKGROUND:Landmark and ultrasound-guided transversus abdominis plane blocks have demonstrated an opioid-sparing effect postoperatively after cesarean delivery. The more posterior quadratus lumborum (QL) might provide superior local anesthetic spread to the thoracolumbar fascia and paravertebral space. The aim of our s...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Krohg A,Ullensvang K,Rosseland LA,Langesæter E,Sauter AR

    更新日期:2018-02-01 00:00:00

  • Culture-Negative and Culture-Positive Sepsis: A Comparison of Characteristics and Outcomes.

    abstract:BACKGROUND:The primary objective of this study was to compare the characteristics of culture-positive and culture-negative status in septic patients. We also determined whether culture status is associated with mortality and whether unique variables are associated with mortality in culture-positive and culture-negative...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Sigakis MJG,Jewell E,Maile MD,Cinti SK,Bateman BT,Engoren M

    更新日期:2019-11-01 00:00:00

  • Continuous gastric decompression for postoperative nausea and vomiting after coronary revascularization surgery.

    abstract::Postoperative nausea and vomiting is common after cardiac surgery and may contribute to significant morbidity. Gastric decompression during anesthesia has been used for postoperative nausea and vomiting prophylaxis in shorter duration noncardiac surgery with conflicting results. We tested the hypothesis that gastric d...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Burlacu CL,Healy D,Buggy DJ,Twomey C,Veerasingam D,Tierney A,Moriarty DC

    更新日期:2005-02-01 00:00:00

  • Increased plasma concentrations of the mature form of adrenomedullin during cardiac surgery and hepatosplanchnic hypoperfusion.

    abstract::Adrenomedullin is a potent vasodilatory peptide. Plasma adrenomedullin (AM) concentrations increase during and after cardiopulmonary bypass (CPB). However, the cause of this increase and its site of production have not been identified. We investigated the role of the hepatosplanchnic and cerebral circulations in the i...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章


    authors: Yoshikawa D,Kawahara F,Okano N,Hiraoka H,Kadoi Y,Fujita N,Morita T,Goto F

    更新日期:2003-09-01 00:00:00

  • The effect of intravenous administration of dexamethasone on postoperative pain, nausea, and vomiting after intrathecal injection of meperidine.

    abstract:BACKGROUND:Different drugs have been used to enhance postoperative neuraxial opioid analgesia and reduce adverse effects. METHODS:We randomized 60 patients into 2 groups to receive either 2 mL saline or 0.1 mg/kg dexamethasone IV before the administration of intrathecal anesthesia (15 mg and meperidine 15 mg). After s...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验


    authors: Movafegh A,Soroush AR,Navi A,Sadeghi M,Esfehani F,Akbarian-Tefaghi N

    更新日期:2007-04-01 00:00:00

  • The influence of chronic administration of hypnotics and analgesics on rate of recovery from inhalation anesthesia in rats.

    abstract::A series of groups of Sprague-Dawley rats were given either secobarbital, phenobarbital, morphine, pentazocine, diazepam, methotrimeprazine, or saline (control) intraperitoneally on 4 consecutive days and then, on day 5, anesthetized with chloroform, trichlorethylene, fluroxene, halothane, methoxyflurane, enflurane, i...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Dobkin AB,Borgstedt HH,Rohner RF,KURLAN RM,Fein AB

    更新日期:1975-01-01 00:00:00

  • Determination of Geolocations for Anesthesia Specialty Coverage and Standby Call Allowing Return to the Hospital Within a Specified Amount of Time.

    abstract:BACKGROUND:For emergent procedures, in-house teams are required for immediate patient care. However, for many procedures, there is time to bring in a call team from home without increasing patient morbidity. Anesthesia providers taking subspecialty or backup call from home are required to return to the hospital within ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Epstein RH,Dexter F,Diez C,Potnuru P

    更新日期:2019-11-01 00:00:00

  • The direction dependence of thermoregulatory vasoconstriction during isoflurane/epidural anesthesia in humans.

    abstract::We tested the hypothesis that once thermoregulatory vasoconstriction is triggered at a given core temperature during isoflurane anesthesia, redilation starts at a substantially higher core temperature. To avoid direct perception of cutaneous cooling and warming, we used epidural anesthesia and limited our thermal mani...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Ozaki M,Sessler DI,McGuire J,Blanchard D,Schroeder M,Moayeri A

    更新日期:1993-10-01 00:00:00

  • The relationship between bispectral index and propofol during target-controlled infusion anesthesia: a comparative study between children and young adults.

    abstract:BACKGROUND:In this prospective study, we compared the relationship between propofol concentrations and bispectral index (BIS) in children versus young adults anesthetized with target-controlled infusion (TCI) of propofol. METHODS:Forty-five prepubertal subjects (children) and 45 postpubertal subjects (adults) were stu...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Rigouzzo A,Girault L,Louvet N,Servin F,De-Smet T,Piat V,Seeman R,Murat I,Constant I

    更新日期:2008-04-01 00:00:00

  • Clinical trial of a new device for fiberoptic orotracheal intubation (Augustine Scope).

    abstract::Blind oral intubation using the Augustine Guide is helpful for intubating the trachea of patients presenting with difficult airways. This device has been modified by adding a fiberoptic scope with a built-in battery-powered light. We studied this Augustine Scope in 104 patients (Group AS) and compared the results with...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章


    authors: Krafft P,Krenn CG,Fitzgerald RD,Pernerstorfer T,Fridrich P,Weinstabl C

    更新日期:1997-03-01 00:00:00

  • The effect of peripheral opioid block and body cooling on sensitivity to heat in capsaicin-treated skin.

    abstract:UNLABELLED:We sought to determine whether stimulation of opioid receptors during body cooling would alter sensitivity to heat in the heat-sensitized, inflamed skin of 14 healthy volunteers. To investigate the contribution of opioid receptors to nociception, the opioid antagonist naloxone was introduced into the skin by...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Drummond PD

    更新日期:2000-04-01 00:00:00

  • Maximizing prediction probability PK as an alternative semiparametric approach to estimate the plasma effect-site equilibration rate constant ke0.

    abstract:BACKGROUND:The k(e)(0) value is the first order rate constant determining the equilibration of drugs between plasma or end-tidal concentration and effect-site (e.g., brain) concentration. Parametric and semiparametric approaches have been used for estimating individual k(e)(0) values and describing the drug-response cu...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Ellerkmann RK,Bruhn J,Soehle M,Kehrer M,Hoeft A,Kreuer S

    更新日期:2009-11-01 00:00:00

  • Isoflurane has a greater margin of safety than halothane in swine with and without major surgery or critical coronary stenosis.

    abstract::The fatal/anesthetic ratio (FAR) in 44 swine weighing 32.6 +/- 0.7 kg (SEM) was determined. Fatal anesthetic concentration (the numerator for FAR) was defined as the end-tidal concentration at which the pig lived at least 10 min, during experiments that involved step increments in anesthetic concentrations. Previously...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Roberts SL,Gilbert M,Tinker JH

    更新日期:1987-06-01 00:00:00

  • Dietary omega-3 fatty acids may be associated with increased neuropathic pain in nerve-injured rats.

    abstract:UNLABELLED:Certain dietary proteins and oils are capable of decreasing chronic neuropathic pain levels in rats after partial sciatic nerve ligation injury. We tested, for the first time, the role of dietary polyunsaturated fatty acids in suppressing pain in partial sciatic nerve ligation-injured rats. Six groups of mal...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Pérez J,Ware MA,Chevalier S,Gougeon R,Shir Y

    更新日期:2005-08-01 00:00:00

  • Sciatic cryoneurolysis in rats: a model of sympathetically independent pain. Part 1: Effects of sympathectomy.

    abstract::The purpose of this study was to evaluate the effects of preemptive and postlesion sympathectomy in the sciatic cryoneurolysis (SCN) model of neuropathic pain in rats. SCN in rats produces a prolonged significant mechanical allodynia (hypersensitivity to previously non-noxious mechanical stimuli) with no thermal hyper...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章


    authors: Willenbring S,Beauprie IG,DeLeo JA

    更新日期:1995-09-01 00:00:00

  • Evidence for the Efficacy of Systemic Opioid-Sparing Analgesics in Pediatric Surgical Populations: A Systematic Review.

    abstract::While a large number of studies has examined the efficacy of opioid-sparing analgesics in adult surgical populations, fewer studies are available to guide postoperative pain treatment in pediatric patients. We systematically reviewed available publications on the use of systemic nonopioid agents for postoperative anal...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审


    authors: Zhu A,Benzon HA,Anderson TA

    更新日期:2017-11-01 00:00:00

  • Hypercapnia improves tissue oxygenation in morbidly obese surgical patients.

    abstract::Risk of wound infection is increased in morbidly obese surgical patients, in part because a major determinant of wound infection risk, tissue oxygenation, is marginal. Unlike in lean patients, supplemental inspired oxygen (Fio2) only slightly improves tissue oxygenation in obese patients. Mild hypercapnia improves tis...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验


    authors: Hager H,Reddy D,Mandadi G,Pulley D,Eagon JC,Sessler DI,Kurz A

    更新日期:2006-09-01 00:00:00

  • Electro-acupuncture at the Zusanli, Yanglingquan, and Kunlun points does not reduce anesthetic requirement.

    abstract:UNLABELLED:We tested the hypothesis that electro-acupuncture at the Zusanli, Yanglingquan, and Kunlun acupuncture points on the legs decreases anesthetic requirement. Fourteen young, healthy volunteers were anesthetized with desflurane on two separate days. Needle electrodes were positioned at the three acupuncture poi...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章


    authors: Morioka N,Akça O,Doufas AG,Chernyak G,Sessler DI

    更新日期:2002-07-01 00:00:00

  • Does arginine vasopressin influence the coagulation system in advanced vasodilatory shock with severe multiorgan dysfunction syndrome?

    abstract::Arginine vasopressin (AVP) is a potent supplementary vasopressor in advanced vasodilatory shock, but decreases in platelet count have been reported during AVP therapy. In this study we evaluated the effects of AVP infusion on the coagulation system in advanced vasodilatory shock when compared to norepinephrine (NE) in...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Dünser MW,Fries DR,Schobersberger W,Ulmer H,Wenzel V,Friesenecker B,Hasibeder WR,Mayr AJ

    更新日期:2004-07-01 00:00:00