Inhaled nitric oxide versus intravenous vasodilators in severe pulmonary hypertension after cardiac surgery.

abstract：BACKGROUND:The blood/gas partition coefficient of a certain volatile anesthetic is of clinical importance because it determines its velocity of uptake into and elimination from the body of a patient and thus its pharmacokinetic behavior. To date, the blood/gas partition coefficients of isoflurane, sevoflurane, and desf...

journal_title：Anesthesia and analgesia

authors： Esper T,Wehner M,Meinecke CD,Rueffert H

更新日期：2015-01-01 00:00:00

abstract：:In the perioperative period, artificial colloids are most often infused in doses of 500-1000 mL intravenously. This randomized study compared the effects on intravascular volume and coagulation of approximately 2000 mL of two isooncotic artificial colloids: 6% hydroxyethyl starch (HES; MW 200,000; substitution ratio 0...

journal_title：Anesthesia and analgesia

authors： Mortelmans YJ,Vermaut G,Verbruggen AM,Arnout JM,Vermylen J,Van Aken H,Mortelmans LA

更新日期：1995-12-01 00:00:00

abstract：:We studied the effect of large-dose intrathecal sufentanil (ITS) for major abdominal surgery on the hormonal stress response. Forty patients were randomly allocated to receive either IV sufentanil (IVS) or 150 microg of ITS as part of general anesthesia. In the IVS group, adrenocorticotropic hormone (ACTH) and cortiso...

journal_title：Anesthesia and analgesia

authors： Borgdorff PJ,Ionescu TI,Houweling PL,Knape JT

更新日期：2004-10-01 00:00:00

abstract：UNLABELLED:To evaluate the efficacy and acceptance of a new posterior subgluteus approach to the sciatic nerve, as compared with the classic posterior approach, 128 patients undergoing foot orthopedic procedures were randomly allocated to receive either the classic posterior sciatic nerve block (Group Labat, n = 64) or...

journal_title：Anesthesia and analgesia

authors： di Benedetto P,Bertini L,Casati A,Borghi B,Albertin A,Fanelli G

更新日期：2001-10-01 00:00:00

abstract：:The development of a technique for studying spinal dorsal horn electrophysiology in intact, awake, drug-free cats enables the study of spinal sites and mechanisms of action of anesthetic and analgesic agents in a system that more closely reflects normal physiology. Using this technique, we reevaluated the effect of ke...

journal_title：Anesthesia and analgesia

authors： Collins JG

更新日期：1986-11-01 00:00:00

abstract：:Continuous positive airway pressure (CPAP) of 5 and 10 cm H2O applied to the nonventilated lung is effective in improving arterial oxygenation during one-lung ventilation (1-LV). The effectiveness of lower levels of CPAP on improving oxygenation, however, has not been reported, possibly because of limitations of previ...

journal_title：Anesthesia and analgesia

authors： Hogue CW Jr

更新日期：1994-08-01 00:00:00

abstract：:A 19-year-old African American man with a T12 spinal cord lesion underwent a T4-L5 thoracolumbar spinal fusion. Intraoperatively, his arterial blood pressure acutely increased from 110/60 to 260/130 mm Hg without a change in heart rate. The patient did not have pheochromocytoma, carcinoid syndrome, or thyroid storm. T...

journal_title：Anesthesia and analgesia

authors： Blacker SN,Brown CQ,Tarant NS

更新日期：2010-11-01 00:00:00

abstract：UNLABELLED:Adjuncts to local anesthetics for peripheral plexus blockade may enhance the quality and duration of anesthesia and postoperative analgesia. The analgesic, tramadol, has a unique mechanism of action that suggests efficacy as such an adjunct. It displays a central analgesic and peripheral local anesthetic eff...

journal_title：Anesthesia and analgesia

authors： Robaux S,Blunt C,Viel E,Cuvillon P,Nouguier P,Dautel G,Boileau S,Girard F,Bouaziz H

更新日期：2004-04-01 00:00:00

abstract：:We compared the effects of the lightwand technique on hemodynamic responses, time-to-intubation, number of attempts, and complications during tracheal intubation with those of direct-vision laryngoscopy in normotensive (LN and TN group; n = 20, respectively) and hypertensive (LH and TH group; n = 20, respectively) pat...

journal_title：Anesthesia and analgesia

authors： Nishikawa K,Omote K,Kawana S,Namiki A

更新日期：2000-05-01 00:00:00

abstract：:The purpose of this study was to determine if the addition of sufentanil would improve the quality of analgesia obtained with 0.125% epidural bupivacaine infusions given to women in active labor. Forty healthy laboring women were randomly assigned to two equal groups. Group 1 had epidural analgesia instituted with the...

journal_title：Anesthesia and analgesia

authors： Phillips G

更新日期：1988-05-01 00:00:00

abstract：:The evolution of modern anesthesia and surgical practices has been accompanied by enhanced supportive procedures in blood banking and transfusion medicine. There is increased focus on the preparation and the use of blood components including, but not limited to, preventing unnecessary type and screen/crossmatch orders...

journal_title：Anesthesia and analgesia

authors： White MJ,Hazard SW 3rd,Frank SM,Boyd JS,Wick EC,Ness PM,Tobian AA

更新日期：2015-06-01 00:00:00

abstract：:The purpose of these experiments was to analyze the cerebrovascular and cerebral metabolic effects of midazolam, a short-acting water-soluble benzodiazepine, and to investigate its interaction with alcohol in rats. A benzodiazepine antagonist, 3-carbo-t-butoxy-beta-carboline (beta-CCT), was used to test the role of th...

journal_title：Anesthesia and analgesia

authors： Van Gorder PN,Hoffman WE,Baughman V,Albrecht RF,Miletich DJ,Guzman F,Cook JM

更新日期：1985-02-01 00:00:00

abstract：UNLABELLED:Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, has psychotomimetic activity. NMDA receptor antagonists cause morphological damage in the posterior cingulate cortex, which may be the brain region responsible for their psychotomimetic effects. Benzodiazepines are effective in preve...

journal_title：Anesthesia and analgesia

authors： Nagata A,Nakao S,Miyamoto E,Inada T,Tooyama I,Kimura H,Shingu K

更新日期：1998-12-01 00:00:00

abstract：:Aprotinin, a potent antifibrinolytic drug, reduces the proportion of adults who receive blood transfusions during cardiac surgery, although the effect in children remains unclear. We performed a systematic review of the literature to identify all English language, randomized controlled trials of aprotinin involving ch...

journal_title：Anesthesia and analgesia

authors： Arnold DM,Fergusson DA,Chan AK,Cook RJ,Fraser GA,Lim W,Blajchman MA,Cook DJ

更新日期：2006-03-01 00:00:00

abstract：:Cardioprotection by anesthetic preconditioning (APC) can be abolished by nitric oxide (NO*) synthase inhibitors or by reactive oxygen species (ROS) scavengers. We previously reported attenuated mitochondrial electron transport (ET) and increased ROS generation during preconditioning sevoflurane exposure as part of the...

journal_title：Anesthesia and analgesia

authors： Riess ML,Kevin LG,McCormick J,Jiang MT,Rhodes SS,Stowe DF

更新日期：2005-01-01 00:00:00

abstract：:The effects of three anesthetic techniques on liver function were compared in patients with mild alcoholic hepatitis who required surgery, both peripheral and superficial. Thirty patients were randomly assigned to receive one of three anesthetics: thiopental, nitrous oxide and oxygen, enflurane, plus muscle relaxant; ...

journal_title：Anesthesia and analgesia

authors： Zinn SE,Fairley HB,Glenn JD

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Clonidine is an alpha(2) adrenoreceptor and imidazoline receptor agonist, which has analgesic, sedative, and minimum alveolar anesthetic concentration-sparing effects. It has been used orally, IV, and epidurally. In spinal surgery, there is a reluctance to use local anesthetic-based epidural analgesia postop...

journal_title：Anesthesia and analgesia

authors： Farmery AD,Wilson-MacDonald J

更新日期：2009-02-01 00:00:00

abstract：:Patients undergoing potentially painful interventional radiological procedures generally require a combination of analgesia and sedation. This sedation/analgesia should allow the patient to communicate while also remaining calm. Bispectral index (BIS) monitoring could be useful in achieving this. The primary end-point...

journal_title：Anesthesia and analgesia

authors： Dahaba AA,Lischnig U,Kronthaler R,Bornemann H,Georgiev V,Rehak PH,Metzler H

更新日期：2006-08-01 00:00:00

abstract：UNLABELLED:We compared the ketoprofen-propacetamol combination relative to propacetamol alone in thyroid and parathyroid surgery in terms of postoperative analgesic efficacy, bleeding, and incidence of nausea and vomiting to determine whether ketoprofen results in any benefit in this type of surgery. Patients were dist...

journal_title：Anesthesia and analgesia

authors： Basto ER,Waintrop C,Mourey FD,Landru JP,Eurin BG,Jacob LP

更新日期：2001-04-01 00:00:00

abstract：:One of the most prevalent symptoms after major surgery is pain. When postoperative pain treatment is unsatisfactory, it can lead to poor surgical recovery, decreased quality of life, and increased health care costs. Current analgesics, single or in combination, have limited efficacy due to low potency, limited duratio...

journal_title：Anesthesia and analgesia

authors： Cata JP,Gorur A,Yuan X,Berg NK,Sood AK,Eltzschig HK

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Isoflurane activates vascular adenosine triphosphate sensitive potassium (K(ATP)) channels, and may induce vasodilation. In the present study, we investigated whether hyperglycemia modifies isoflurane activation of vascular K(ATP) channel. METHODS:We used a cell-attached patch-clamp configuration to test th...

journal_title：Anesthesia and analgesia

authors： Kawano T,Tanaka K,Mawatari K,Oshita S,Takahashi A,Nakaya Y

更新日期：2008-03-01 00:00:00

abstract：UNLABELLED:Reductions in cerebral venous oxyhemoglobin saturation (SjO2) occur during the rewarming phase of hypothermic cardiopulmonary bypass (CPB). We prospectively investigated the effects of propofol on these reductions in SjO2 (SjO2 <50%). Fiberoptic jugular bulb catheters were inserted in 30 patients undergoing ...

journal_title：Anesthesia and analgesia

authors： Souter MJ,Andrews PJ,Alston RP

更新日期：1998-05-01 00:00:00

abstract：:A randomized double-blind study was conducted in 50 orthopedic patients to determine the effect of epinephrine and phenylephrine on the anesthetic properties of intrathecally administered tetracaine. Two doses of each vasoconstrictor agent were studied: 0.2 mg of epinephrine, 0.3 mg of epinephrine, 1 mg of phenylephri...

journal_title：Anesthesia and analgesia

authors： Concepcion M,Maddi R,Francis D,Rocco AG,Murray E,Covino BG

更新日期：1984-02-01 00:00:00

abstract：:Qualitative arterial waveform analysis has been in existence for millennia; quantitative arterial waveform analysis techniques, which can be traced back to Euler's work in the 18th century, have not been widely used by anesthesiologists and other clinicians. This is likely attributable, in part, to the widespread use ...

journal_title：Anesthesia and analgesia

authors： Thiele RH,Durieux ME

更新日期：2011-10-01 00:00:00

abstract：:The purpose of this canine study was to examine the cerebral vascular and metabolic effects of adding nitrous oxide to isoflurane from 1.4% expired (1 MAC) up to a concentration giving an isoelectric electroencephalogram (EEG). Cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) were determined us...

journal_title：Anesthesia and analgesia

authors： Roald OK,Forsman M,Heier MS,Steen PA

更新日期：1991-01-01 00:00:00

abstract：:Ten volunteers were studied during six stages of propofol sedation, namely awake (no propofol), light sedation (small dose of propofol), deep sedation (large dose), deep sedation with stimulation of the ulnar nerve, then light sedation again (small dose), and awake (recovery). Light and deep sedation were defined in t...

journal_title：Anesthesia and analgesia

authors： Andrade J,Sapsford DJ,Jeevaratnum D,Pickworth AJ,Jones JG

更新日期：1996-12-01 00:00:00

abstract：UNLABELLED:We evaluated the effects of aggressive warming and maintenance of normothermia on surgical blood loss and allogeneic transfusion requirement. We randomly assigned 150 patients undergoing total hip arthroplasty with spinal anesthesia to aggressive warming (to maintain a tympanic membrane temperature of 36.5 d...

journal_title：Anesthesia and analgesia

authors： Winkler M,Akça O,Birkenberg B,Hetz H,Scheck T,Arkiliç CF,Kabon B,Marker E,Grübl A,Czepan R,Greher M,Goll V,Gottsauner-Wolf F,Kurz A,Sessler DI

更新日期：2000-10-01 00:00:00

abstract：:Lidocaine and MgSO4 are often coadministered to patients with pregnancy-induced hypertension. This study examined whether MgSO4 alters the lidocaine-seizure threshold in the rat and, if so, whether systemic MgSO4 administration is as effective as intracerebroventricular MgSO4 infusion. In Experiment 1, rats were admin...

journal_title：Anesthesia and analgesia

authors： Kim YJ,McFarlane C,Warner DS,Baker MT,Choi WW,Dexter F

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:To prevent reflex-induced bronchoconstriction in patients with asthma, local anesthetics are commonly administered by aerosol or IV as adjunct medication. Lidocaine attenuates responsiveness to a neurally active stimulus that increases tone, but there is scant information about the effect of lidocaine on bas...

journal_title：Anesthesia and analgesia

authors： Chang HY,Togias A,Brown RH

更新日期：2007-05-01 00:00:00

abstract：UNLABELLED:We evaluated the timing effect of a 10-mg IV administration of dexamethasone on its efficacy as a prophylactic antiemetic on postoperative nausea and vomiting (PONV). One hundred twenty women (n = 40 in each of three groups) undergoing abdominal total hysterectomy under general anesthesia were enrolled in th...

journal_title：Anesthesia and analgesia

authors： Wang JJ,Ho ST,Tzeng JI,Tang CS

更新日期：2000-07-01 00:00:00