Trends in the Prevalence of Intraoperative Adverse Events at Two Academic Hospitals After Implementation of a Mandatory Reporting System.

Abstract:

BACKGROUND:Anesthesia information management systems (AIMSs) have been effectively used to improve quality in anesthesia care, and have enabled the development of mandatory quality assurance (QA) reporting systems for adverse events (AEs). While this approach has been shown to increase event reporting over time, the long-term effect of such a system on quality is unknown. We investigated the trends in AE reporting over time after implementing AIMS-based mandatory reporting systems at 2 academic medical centers. METHODS:At Thomas Jefferson University Hospital, AEs were retrieved after implementation of a mandatory QA process in 2013. These AEs were categorized as preventable and unpreventable. The rates of overall preventable and unpreventable AEs were analyzed over time. At Vanderbilt University Medical Center, the rates of AEs were analyzed after establishing a mandatory QA process in 2002. Data were binned by quarter, and trends over time were analyzed using the Mann-Kendall test. RESULTS:At Thomas Jefferson University Hospital, over a period of 2 years after implementation of a mandatory QA process, the documented AE rate decreased from 1.23% to 0.64% (P < .0001). This decrease occurred primarily in the group of preventable AEs, which declined from 1.01% to 0.52% (P = .014). The rate of unpreventable AEs was unchanged, from 0.22% to 0.12% (P = .12). At Vanderbilt University Medical Center, over a 7-year period after implementation, the AE rate decreased from 4.20% to 1.36% (P < .0001). CONCLUSIONS:After implementation of a mandatory QA process at 2 academic medical centers, documented AE rates decreased significantly. The decrease observed in preventable AEs, with unchanged rates of unpreventable AEs, demonstrates that mandatory reporting of intraoperative AEs was followed by a reduction in preventable intraoperative AEs. If our findings are replicated at other institutions and are shown to have a stronger trend compared with institutions where the implementation was not conducted, or there was a change from preimplementation trends, adding mandatory perioperative outcomes reporting in the AIMS may represent a valuable method to improve the overall safety of anesthesia.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Wanderer JP,Gratch DM,Jacques PS,Rodriquez LI,Epstein RH

doi

10.1213/ANE.0000000000002447

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

134-140

issue

1

eissn

0003-2999

issn

1526-7598

journal_volume

126

pub_type

杂志文章,多中心研究
  • A manual slide rule for target-controlled infusion of propofol: development and evaluation.

    abstract:UNLABELLED:We describe the development and evaluation of a simple slide rule that enables the bedside determination of the infusion rate for a particular target plasma concentration of propofol. The infusion rate to reach this target concentration at time (t) is the product of the target concentration, body weight, and...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200301000-00029

    authors: Bruhn J,Bouillon TW,Röpcke H,Hoeft A

    更新日期:2003-01-01 00:00:00

  • Associations Between Impaired Cerebral Blood Flow Autoregulation, Cerebral Oxygenation, and Biomarkers of Brain Injury and Postoperative Cognitive Dysfunction in Elderly Patients After Major Noncardiac Surgery.

    abstract:BACKGROUND:Increasing evidence links postoperative cognitive dysfunction (POCD) to surgery and anesthesia. POCD is recognized as an important neuropsychological adverse outcome in surgical patients, particularly the elderly. This prospective cohort study aimed to investigate whether POCD is associated with impaired int...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000001803

    authors: Goettel N,Burkhart CS,Rossi A,Cabella BC,Berres M,Monsch AU,Czosnyka M,Steiner LA

    更新日期:2017-03-01 00:00:00

  • Systemic mexiletine relieves chronic allodynialike symptoms in rats with ischemic spinal cord injury.

    abstract::We have recently reported a chronic allodynialike symptom in rats after ischemic spinal cord injury. This pain-related behavior is resistant to a number of pharmacologic treatments, including morphine, clonidine, carbamazepine, baclofen, and muscimol. In the present report, we present evidence indicating that systemic...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-199205000-00005

    authors: Xu XJ,Hao JX,Seiger A,Arnér S,Lindblom U,Wiesenfeld-Hallin Z

    更新日期:1992-05-01 00:00:00

  • The influence of the tonsillar gag on efficacy of seal, anatomic position, airway patency, and airway protection with the flexible laryngeal mask airway: a randomized, cross-over study of fresh adult cadavers.

    abstract:UNLABELLED:We conducted a randomized, controlled, cross-over cadaver study to test the hypothesis that the efficacy of seal for ventilation and airway protection, anatomic position, and airway patency with the flexible laryngeal mask airway (FLMA) are altered by the application of a Boyle Davis (B-D) gag. We also deter...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-199907000-00032

    authors: Brimacombe JR,Keller C,Gunkel AR,Pühringer F

    更新日期:1999-07-01 00:00:00

  • Review of the off-label use of recombinant activated factor VII in pediatric cardiac surgery patients.

    abstract::In recent years the off-label use of recombinant activated factor VII (rFVIIa) has markedly increased, particularly in pediatric cardiac surgery patients, and practitioners differ widely in their usage of the drug. In 2009, the Congenital Cardiac Anesthesia Society (CCAS) assembled a task force to review the literatur...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:10.1213/ANE.0b013e31825aff10

    authors: Guzzetta NA,Russell IA,Williams GD

    更新日期:2012-08-01 00:00:00

  • Autonomic dysreflexia-like syndrome in a T12 paraplegic during thoracic spine surgery.

    abstract::A 19-year-old African American man with a T12 spinal cord lesion underwent a T4-L5 thoracolumbar spinal fusion. Intraoperatively, his arterial blood pressure acutely increased from 110/60 to 260/130 mm Hg without a change in heart rate. The patient did not have pheochromocytoma, carcinoid syndrome, or thyroid storm. T...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3181f334b8

    authors: Blacker SN,Brown CQ,Tarant NS

    更新日期:2010-11-01 00:00:00

  • Aromatherapy as treatment for postoperative nausea: a randomized trial.

    abstract:BACKGROUND:Postoperative nausea (PON) is a common complication of anesthesia and surgery. Antiemetic medication for higher-risk patients may reduce but does not reliably prevent PON. We examined aromatherapy as a treatment for patients experiencing PON after ambulatory surgery. Our primary hypothesis was that in compar...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0b013e31824a0b1c

    authors: Hunt R,Dienemann J,Norton HJ,Hartley W,Hudgens A,Stern T,Divine G

    更新日期:2013-09-01 00:00:00

  • A Cross-Sectional Survey to Determine the Prevalence of Burnout Syndrome Among Anesthesia Providers in Zambian Hospitals.

    abstract:BACKGROUND:Burnout is a psychological syndrome that results from chronic exposure to job stress. It is defined by a triad of emotional exhaustion, depersonalization, and reduced personal accomplishment. In research, mostly from high-income countries, burnout is common in health care professionals, especially in anesthe...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000004464

    authors: Mumbwe MC,McIsaac D,Jarman A,Bould MD

    更新日期:2020-02-01 00:00:00

  • Dexmedetomidine Versus Remifentanil for Monitored Anesthesia Care During Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: A Randomized Controlled Trial.

    abstract:BACKGROUND:We hypothesized that, compared to remifentanil, dexmedetomidine used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) performed under monitored anesthesia care (MAC) in nonintubated patients would result in fewer episodes of major respiratory adverse events (number of episodes...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0000000000003633

    authors: St-Pierre P,Tanoubi I,Verdonck O,Fortier LP,Richebé P,Côté I,Loubert C,Drolet P

    更新日期:2019-01-01 00:00:00

  • Right Ventricular Longitudinal Strain Is Depressed in a Bovine Model of Pulmonary Hypertension.

    abstract:BACKGROUND:Pulmonary hypertension and resulting right ventricular (RV) dysfunction are associated with significant perioperative morbidity and mortality. Although echocardiography permits real-time, noninvasive assessment of RV function, objective and comparative measures are underdeveloped, and appropriate animal mode...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000001215

    authors: Bartels K,Brown RD,Fox DL,Bull TM,Neary JM,Dorosz JL,Fonseca BM,Stenmark KR

    更新日期:2016-05-01 00:00:00

  • Nonuniform behavior of intravenous anesthetics on postischemic adhesion of neutrophils in the guinea pig heart.

    abstract:UNLABELLED:Adhesion of polymorphonuclear neutrophils (PMN) to the coronary endothelium is a crucial step in the development of ischemic myocardial injury. We tested the possible effects of six widely used IV anesthetics on non- and postischemic coronary adhesion of PMN in isolated perfused guinea pig hearts. Hearts (n ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200006000-00007

    authors: Szekely A,Heindl B,Zahler S,Conzen PF,Becker BF

    更新日期:2000-06-01 00:00:00

  • A spray catheter technique for pleural anesthesia: a novel method for pain control before talc poudrage.

    abstract:BACKGROUND:Chemical pleurodesis causes severe pain, prompting physicians to perform thoracoscopic talc poudrage under general or neuroleptanalgesia. We describe a novel method for pain control in five patients with pneumothoraces and severe chronic obstructive pulmonary disease. METHODS:Patients were premedicated with...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1213/01.ane.0000249046.02025.ef

    authors: Lee P,Colt HG

    更新日期:2007-01-01 00:00:00

  • Pressure control ventilation: three anesthesia ventilators compared using an infant lung model.

    abstract:UNLABELLED:We compared three ventilators-Servo 900C (Siemens Medical Systems, Danvers, MA), Aestiva 3000 (Datex-Ohmeda, Madison, WI), and NAD 6000 (North American Dräger, Telford, PA)-set to deliver pressure control ventilation using an infant test lung model. Ventilator settings were selected to test "near-maximum" se...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200011000-00020

    authors: Stayer SA,Bent ST,Skjonsby BS,Frolov A,Andropoulos DB

    更新日期:2000-11-01 00:00:00

  • Sign of complete sympathetic blockade: sweat test or sympathogalvanic response?

    abstract::The sensitivity, specificity, and accuracy of the cobalt blue and ninhydrin sweat tests were compared with the sympathogalvanic response (SGR) in assessment of complete sympathetic blockade. Patients were randomly assigned to receive epidural administration of either preservative-free physiologic saline solution and 8...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Benzon HT,Cheng SC,Avram MJ,Molloy RE

    更新日期:1985-04-01 00:00:00

  • Joint hypothesis testing and gatekeeping procedures for studies with multiple endpoints.

    abstract::A claim of superiority of one intervention over another often depends naturally on results from several outcomes of interest. For such studies the common practice of making conclusions about individual outcomes in isolation can be problematic. For example, an intervention might be shown to improve one outcome (e.g., p...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3182504435

    authors: Mascha EJ,Turan A

    更新日期:2012-06-01 00:00:00

  • Ketamine potentiates nondepolarizing neuromuscular relaxants in a primate.

    abstract::Ketamine has many neuromuscular effects in vitro. Its neuromuscular effects in vivo have been controversial and inconsistent. To systematically examine its neuromuscular effects over a wide dose range and its interaction with all popular nondepolarizing neuromuscular relaxants, the effects of ketamine 2, 5, and 10 mg/...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Tsai SK,Lee C

    更新日期:1989-01-01 00:00:00

  • A preplanned treatment for malignant hyperpyrexia.

    abstract::Although a rare complication of general anesthesia, unanticipated malignant hyperpyrexia requires a rapid, organized treatment plan. With the aid of a treatment protocol sheet and a compact drug and cooling package, treatment can be implemented quickly in each operating room. ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-197609000-00022

    authors: Fraser JG,Crumrine RS,Izant RJ Jr

    更新日期:1976-09-01 00:00:00

  • A comparison of cerebral blood flow reactivity to CO2 during halothane versus isoflurane anesthesia for carotid endarterectomy.

    abstract::The effects of isoflurane or halothane on cerebral blood flow (CBF) reactivity to changes in arterial carbon dioxide tension (PaCO2) during carotid endarterectomy were compared using the intravenous method of 133Xe-CBF determination. Patients, aged 65 +/- 3 yr (mean +/- SE), received O2 and N2O (1:1) and either 0.75% ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:

    authors: Young WL,Prohovnik I,Correll JW,Ostapkovich N,Ornstein E,Quest DO

    更新日期:1991-10-01 00:00:00

  • The effects of glycopyrrolate on oral mucous host defenses in healthy volunteers.

    abstract:UNLABELLED:We studied the effects of glycopyrrolate on oral mucous host defenses. Single IV doses of glycopyrrolate (4 microg/kg) or placebo were administered to 12 healthy volunteers in a randomized, double-blinded, cross-over study. Salivary flow rates and the concentrations/activities of total protein, amylase, and ...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200008000-00045

    authors: Lähteenmäki MT,Salo MS,Tenovuo JO,Helminen AV,Vilja PJ,Huupponen RK

    更新日期:2000-08-01 00:00:00

  • Effects of patient age, pH of cerebrospinal fluid, and vasopressors on onset and duration of spinal anesthesia.

    abstract::Two hundred twenty-two spinal anesthesias were administered with 10 mg. of tetracaine and 1 ml. of 10 percent dextrose to investigate the effects of vasopressors, patients age, and pH of cerebrospinal fluid on the onset and duration of spinal anesthesia. Neither the differences in overall age, cerebrospinal fluid pH, ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Park WY,Balingit PE,Macnamara TE

    更新日期:1975-07-01 00:00:00

  • Verifying correct endotracheal intubation by measurement of end-tidal carbon dioxide during an ex utero intrapartum treatment procedure.

    abstract::The ex utero intrapartum treatment (EXIT) procedure provides time to secure the airway of the fetus while utero-placental circulation supplies the fetus with oxygen. We report the anesthetic management of a fetus with a large neck mass during an EXIT procedure in which the confirmation of correct endotracheal intubati...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ANE.0000175206.91231.77

    authors: Eschertzhuber S,Keller C,Mitterschiffthaler G,Jochberger S,Kühbacher G

    更新日期:2005-09-01 00:00:00

  • Propacetamol as adjunctive treatment for postoperative pain after cardiac surgery.

    abstract:UNLABELLED:Postoperative pain management after cardiac surgery has been mainly based on parenteral opioids. However, because opioids have numerous side effects, coadministration of non-opioid analgesics has been introduced as a method of reducing opioid dose. In this prospective, randomized, double-blinded study, we ev...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200210000-00005

    authors: Lahtinen P,Kokki H,Hendolin H,Hakala T,Hynynen M

    更新日期:2002-10-01 00:00:00

  • Intravenous ketoprofen in thyroid and parathyroid surgery.

    abstract:UNLABELLED:We compared the ketoprofen-propacetamol combination relative to propacetamol alone in thyroid and parathyroid surgery in terms of postoperative analgesic efficacy, bleeding, and incidence of nausea and vomiting to determine whether ketoprofen results in any benefit in this type of surgery. Patients were dist...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200104000-00047

    authors: Basto ER,Waintrop C,Mourey FD,Landru JP,Eurin BG,Jacob LP

    更新日期:2001-04-01 00:00:00

  • Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats.

    abstract:BACKGROUND:Nerve injury can generate neuropathic pain. The accompanying mechanical allodynia may be reduced by the intrathecal administration of adenosine. The neuroprotective effects of adenosine are mediated by the adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channel. We assessed the relationship between...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e318212b833

    authors: Song JG,Hahm KD,Kim YK,Leem JG,Lee C,Jeong SM,Park PH,Shin JW

    更新日期:2011-06-01 00:00:00

  • The ulinastatin-induced effect on neuromuscular block caused by vecuronium.

    abstract:UNLABELLED:We examined the effect of ulinastatin, a protease inhibitor purified from human urine, on neuromuscular block caused by vecuronium. Sixty adult patients were randomly divided into four groups of 15 patients each: ulinastatin-posttetanic count (U-PTC), ulinastatin-train-of-four (U-TOF), control-posttetanic co...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验,收录出版

    doi:10.1097/00000539-199912000-00048

    authors: Saitoh Y,Fujii Y,Oshima T

    更新日期:1999-12-01 00:00:00

  • Carbon Dioxide Absorption During Inhalation Anesthesia: A Modern Practice.

    abstract::CO2 absorbents were introduced into anesthesia practice in 1924 and are essential when using a circle system to minimize waste by reducing fresh gas flow to allow exhaled anesthetic agents to be rebreathed. For many years, absorbent formulations consisted of calcium hydroxide combined with strong bases like sodium and...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000005137

    authors: Feldman JM,Hendrickx J,Kennedy RR

    更新日期:2020-09-14 00:00:00

  • Nitrous oxide attenuates pressor but augments norepinephrine response to laryngoscopy and endotracheal intubation.

    abstract:UNLABELLED:Nitrous oxide (N(2)O) exerts a sympathomimetic action. We investigated whether N(2)O modifies the cardiovascular responses to tracheal intubation during general anesthesia. One-hundred healthy patients were assigned randomly to receive one of four concentrations (0%, 25%, 50%, or 75%; n = 25 each) of N(2)O i...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/01.ane.0000058842.05373.e3

    authors: Yoo KY,Jeong ST,Ha IH,Lee J

    更新日期:2003-05-01 00:00:00

  • Quantification of Fibrinolysis Using Velocity Curves Measured with Thromboelastometry in Children with Congenital Heart Disease.

    abstract:BACKGROUND:In this pilot study, we hypothesized that velocity parameters obtained from changes in clot amplitude (A) and clot elasticity (E) measured with thromboelastometry (ROTEM, Tem International GmbH, Munich, Germany) could improve detection of fibrinolysis in whole blood obtained from children undergoing surgery ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000000795

    authors: Faraoni D,Van der Linden P,Ducloy-Bouthors AS,Goobie SM,DiNardo JA,Nielsen VG

    更新日期:2015-08-01 00:00:00

  • Halothane enhances pulmonary artery endothelial eicosanoid release.

    abstract::To determine whether anesthetics alter endothelial eicosanoid release, cultured bovine pulmonary artery endothelial cells were studied during constant flow and pressure perfusion at two oxygen tensions (hypoxia, 50 +/- 2 mm Hg; normoxia, 144 +/- 5 mm Hg; mean +/- SEM) with and without 1% halothane. Endothelialized mic...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-199212000-00022

    authors: Barnes SD,Martin LD,Wetzel RC

    更新日期:1992-12-01 00:00:00

  • Pathogenic Link Between Postextubation Pneumonia and Ventilator-Associated Pneumonia: An Experimental Study.

    abstract:BACKGROUND:The presence of an endotracheal tube is the main cause for developing ventilator-associated pneumonia (VAP), but pneumonia can still develop in hospitalized patients after endotracheal tube removal (postextubation pneumonia [PEP]). We hypothesized that short-term intubation (24 hours) can play a role in the ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000001899

    authors: Rezoagli E,Zanella A,Cressoni M,De Marchi L,Kolobow T,Berra L

    更新日期:2017-04-01 00:00:00