Ketamine potentiates nondepolarizing neuromuscular relaxants in a primate.

abstract：BACKGROUND:The perioperative course of patients undergoing intracranial surgery is frequently complicated by hypertensive episodes. Dexmedetomidine (DEX), an alpha-2 adrenoreceptor agonist, is gaining popularity in neuroanesthesia, because its sympatholytic and antinociceptive properties may improve hemodynamic stabili...

journal_title：Anesthesia and analgesia

authors： Bekker A,Sturaitis M,Bloom M,Moric M,Golfinos J,Parker E,Babu R,Pitti A

更新日期：2008-10-01 00:00:00

abstract：:Sevoflurane appears to have several properties that make it an attractive alternative to the currently available anesthetics for outpatient anesthesia. The relative low solubility of sevoflurane, as well as an impressive lack of airway irritation, makes it a very useful anesthetic for inhalation induction of anesthesi...

journal_title：Anesthesia and analgesia

authors： Smith I,Nathanson MH,White PF

更新日期：1995-12-01 00:00:00

abstract：UNLABELLED:I designed this study to determine the efficacy of heart rate (HR), systolic blood pressure (SBP), and digital skin blood flow (DSBF) in detecting intravascular injection after a simulated epidural test dose containing 15 mug of epinephrine in sevoflurane-anesthetized adults. In addition, the testing thresho...

journal_title：Anesthesia and analgesia

authors： Mowafi HA

更新日期：2005-08-01 00:00:00

abstract：UNLABELLED:One-lung ventilation (OLV) induces an increase in pulmonary shunt sometimes associated with a decrease in PaO2 despite ventilation with 100% oxygen. PaO2 improvement has been reported in one-lung ventilated animals receiving IV almitrine, a pulmonary vasoconstrictor. We evaluated the ability of almitrine to ...

journal_title：Anesthesia and analgesia

authors： Moutafis M,Dalibon N,Liu N,Kuhlman G,Fischler M

更新日期：2002-04-01 00:00:00

abstract：:Procaine hydrochloride was added to cardioplegia and studied for its efficacy in stabilizing the postischemic rhythm after aortic declamping in cardiac surgery. Fifty-six patients scheduled for coronary artery bypass grafting (CABG), were included in a randomized, double-blind study. The patients were anesthetized wit...

journal_title：Anesthesia and analgesia

authors： Sellevold OF,Berg EM,Levang OW

更新日期：1995-11-01 00:00:00

abstract：:Fentanyl pharmacokinetics was compared in two groups of adult patients, one group (n = 5) aged less than 50 years, and one group (n = 4) aged greater than 60 years. Despite equivalent doses of fentanyl (10 microgram/kg IV), serum drug concentrations were significantly higher in the older patient group. This was reflec...

journal_title：Anesthesia and analgesia

authors： Bentley JB,Borel JD,Nenad RE Jr,Gillespie TJ

更新日期：1982-12-01 00:00:00

abstract：:Carbon dioxide insufflation during laparoscopic surgery may interfere with the accuracy of the cardiac output value measured by the NICO2 system. The authors simultaneously measured cardiac output by the thermodilution method and by the carbon dioxide rebreathing technique during laparoscopic adrenalectomy in a patien...

journal_title：Anesthesia and analgesia

authors： Suzuki M,Koda S,Nakamura Y,Kawamura N,Shimada Y

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:We have developed a proportional-integral-derivative controller allowing the closed-loop coadministration of propofol and remifentanil, guided by a Bispectral Index (BIS) monitor, during induction and maintenance of general anesthesia. The controller was compared with manual target-controlled infusion. METH...

journal_title：Anesthesia and analgesia

authors： Liu N,Chazot T,Hamada S,Landais A,Boichut N,Dussaussoy C,Trillat B,Beydon L,Samain E,Sessler DI,Fischler M

更新日期：2011-03-01 00:00:00

abstract：:The effects of gestational age (GA) and plasma protein concentrations on the plasma protein binding of fentanyl and alfentanil were studied in preterm and term neonates. Binding experiments were performed using split-cell equilibrium dialysis. Fentanyl and alfentanil concentrations were measured using specific radioim...

journal_title：Anesthesia and analgesia

authors： Wilson AS,Stiller RL,Davis PJ,Fedel G,Chakravorti S,Israel BA,McGowan FX Jr

更新日期：1997-02-01 00:00:00

abstract：:Morphine plasma concentrations were determined in six patients receiving kidney transplants from living-related donors, and nine patients receiving kidney transplants from cadavers. The total cold ischemic time was about 2 hr for kidneys from living-related donors and 14 hr for those from cadavers. After an intravenou...

journal_title：Anesthesia and analgesia

authors： Sear J,Moore A,Hunniset A,Baldwin D,Allen M,Hand C,McQuay H,Morris P

更新日期：1985-11-01 00:00:00

abstract：UNLABELLED:The finger plethysmographic waveform of pulse oximeters is a qualitative indicator of fingertip perfusion. This waveform has been used to assess the depth of anesthesia. Its cyclical changes associated with mechanical ventilation have also been used to detect changes in blood volume under normotensive condit...

journal_title：Anesthesia and analgesia

authors： Golparvar M,Naddafnia H,Saghaei M

更新日期：2002-12-01 00:00:00

abstract：:Near-infrared spectroscopy (NIRS) is a noninvasive optical technique to monitor cerebral oxygen saturation at the bedside. Despite its applicability, NIRS has had limited clinical use because of concerns about accuracy, noted by intersubject variability in slope and intercept of the line between NIRS- and weighted-ave...

journal_title：Anesthesia and analgesia

authors： Kurth CD,Uher B

更新日期：1997-06-01 00:00:00

abstract：UNLABELLED:In this study, we compared the direct myocardial depressant effects of sevoflurane, isoflurane, and halothane and determined whether an L-type Ca2+ channel agonist, Bay K 8644, could attenuate the myocardial depression induced by these anesthetics in cultured neonatal rat ventricular myocytes. Ventricular my...

journal_title：Anesthesia and analgesia

authors： Kanaya N,Kawana S,Tsuchida H,Miyamoto A,Ohshika H,Namiki A

更新日期：1998-11-01 00:00:00

abstract：:It is not uncommon to observe prolonged CNS depression for several hours following controlled hypotension and halothane anesthesia for neurosurgery. The present study evaluates possible contribution of large doses of trimethaphan to CNS depression. Four adult sheep were placed on transapical left ventricular bypass (T...

journal_title：Anesthesia and analgesia

authors： Wong KC,Peters JL,Roberts TS,McRea JC,Fukumasu H

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:We determined whether whole blood impedance aggregometry using the Multiplate detects the effects of antiplatelet drugs as reliably as does classical light transmission aggregometry (LTA) or the platelet function analyzer PFA-100(R). METHODS:Multiplate (M) assays, measuring changes in electrical resistance ...

journal_title：Anesthesia and analgesia

authors： Velik-Salchner C,Maier S,Innerhofer P,Streif W,Klingler A,Kolbitsch C,Fries D

更新日期：2008-12-01 00:00:00

abstract：UNLABELLED:We tested baicalin for its antiinflammatory and analgesic effects (and the mechanisms) in a rat model of carrageenan-evoked thermal hyperalgesia. Pre- or posttreatment with baicalin (10, 30, or 100 mg/kg intraperitoneally) caused a significant analgesic effect with a similar effect of dose-matched ibuprofen....

journal_title：Anesthesia and analgesia

authors： Chou TC,Chang LP,Li CY,Wong CS,Yang SP

更新日期：2003-12-01 00:00:00

abstract：UNLABELLED:C-fos and Fos expression, frequently used as a neural nociceptive marker, is altered by many drugs. The effects of histamine receptor antagonists on c-fos messenger (m)RNA expression are unknown. We examined the effect of local and systemic administration of pyrilamine (H(1) receptor antagonist) and cimetidi...

journal_title：Anesthesia and analgesia

authors： Ashmawi HA,Chambergo FS,Araújo Palmeira CC,de Paula Posso I

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Rapid establishment of a patent airway in ill or injured patients is a priority for prehospital rescue personnel. Out-of-hospital tracheal intubation can be challenging. Unrecognized esophageal intubation is a clinical disaster. METHODS:We performed an observational, prospective study of consecutive patient...

journal_title：Anesthesia and analgesia

authors： Timmermann A,Russo SG,Eich C,Roessler M,Braun U,Rosenblatt WH,Quintel M

更新日期：2007-03-01 00:00:00

abstract：:Lidocaine decreases the minimum alveolar concentration (MAC) of inhaled anesthetics and has been used clinically to reduce the requirements for other anesthetic drugs. In this study we examined the effects of lidocaine on isoflurane MAC in cats. Six cats were studied. In Experiment 1, the MAC of isoflurane was determi...

journal_title：Anesthesia and analgesia

authors： Pypendop BH,Ilkiw JE

更新日期：2005-01-01 00:00:00

abstract：:We studied the performance of a target-controlled drug infusion device, computer-assisted continuous infusion (CACI). Forty-one volunteers received one of midazolam (n = 11), propofol (n = 10), thiopental (n = 10), or fentanyl (n = 10) in sedative concentrations. Concentrations were kept constant for 45-70 min at five...

journal_title：Anesthesia and analgesia

authors： Veselis RA,Glass P,Dnistrian A,Reinsel R

更新日期：1997-05-01 00:00:00

abstract：UNLABELLED:Pressure infusion devices are often used to administer fluids in the operating room, but they may rarely be associated with serious venous air embolism. We studied the performance of the Level 1 and the Ranger Pressure Infusor in the laboratory. The Ranger delivered less air and delivered fluid faster than t...

journal_title：Anesthesia and analgesia

authors： Eaton MP,Dhillon AK

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Pain in sickle cell disease (SCD) is characterized by episodes of acute pain, primarily responsible for acute health care utilization, and persistent chronic pain. Pain severity and frequency vary significantly among patients with SCD. In this study, we investigated the possible contribution of monoamine gen...

journal_title：Anesthesia and analgesia

authors： Jhun E,He Y,Yao Y,Molokie RE,Wilkie DJ,Wang ZJ

更新日期：2014-11-01 00:00:00

abstract：UNLABELLED:The electrophysiologic effects of sevoflurane are not well characterized in humans. Among patients with refractory epilepsy, this study compared 1) electroencephalographic (EEG) interictal spike activity during wakefulness and sevoflurane anesthesia, and 2) electrocorticographically (ECoG) recorded intericta...

journal_title：Anesthesia and analgesia

authors： Watts AD,Herrick IA,McLachlan RS,Craen RA,Gelb AW

更新日期：1999-11-01 00:00:00

abstract：UNLABELLED:Pain complicates the recovery process after ambulatory surgery. We surveyed 175 ambulatory surgery patients to determine pain severity, analgesic use, relationship of pain to duration of recovery, and the relative importance of various factors to predicting these outcomes. Multivariate regression analysis wa...

journal_title：Anesthesia and analgesia

authors： Pavlin DJ,Chen C,Penaloza DA,Polissar NL,Buckley FP

更新日期：2002-09-01 00:00:00

abstract：:We compared the effect of the lithotomy position on the systolic blood pressure (SBP) with the horizontal position after spinal block. The lithotomy position was performed 5 min after spinal block. The change in SBP was expressed as percent of depression from the baseline value. The SBP increased by the lithotomy posi...

journal_title：Anesthesia and analgesia

authors： Miyabe M,Sonoda H,Namiki A

更新日期：1995-07-01 00:00:00

abstract：UNLABELLED:A new infraclavicular brachial plexus block method has the patient supine with an adducted arm. The target is any of the three cords behind the pectoralis minor muscle. The point of needle insertion is the intersection between the clavicle and the coracoid process. The needle is advanced 0 degrees -30 degree...

journal_title：Anesthesia and analgesia

authors： Klaastad Ø,Smith HJ,Smedby O,Winther-Larssen EH,Brodal P,Breivik H,Fosse ET

更新日期：2004-01-01 00:00:00

abstract：:Changes in cardiac output in response to augmenting cardiac contractility, preload, and heart rate during enflurane anesthesia were examined in 12 open-chested dogs. Cardiac contractility was assessed by the slope of the end-systolic pressure-volume relation (Emax). Dobutamine (3, 6, and 9 micrograms.kg-1.min-1) was a...

journal_title：Anesthesia and analgesia

authors： Sato M,Hoka S,Arimura H,Ono K,Yoshitake J

更新日期：1991-11-01 00:00:00

abstract：IMPLICATIONS:We report the successful use of the laryngeal mask airway for percutaneous endoscopic gastrostomy in an adult patient with a known difficult airway and severe cerebral palsy. ...

journal_title：Anesthesia and analgesia

authors： Brimacombe J,Newell S,Bergin A,McCarthy J,Barry J

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Peripheral neuropathy is a common dose-limiting side effect of chemotherapy. There are no clinically proven analgesics for the treatment of this condition. Drugs from different classes have been tested with mixed results. Identification of novel molecular targets for analgesic(s) is important. Antagonism of ...

journal_title：Anesthesia and analgesia

authors： Wala EP,Crooks PA,McIntosh JM,Holtman JR Jr

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Hyperventilation has been an integral, but poorly validated part of neuroanesthetic practice. We conducted a two-period, crossover, randomized trial to evaluate surgeon-assessed brain bulk and measured intracranial pressure (ICP) in patients undergoing craniotomy for removal of supratentorial brain tumors du...

journal_title：Anesthesia and analgesia

authors： Gelb AW,Craen RA,Rao GS,Reddy KR,Megyesi J,Mohanty B,Dash HH,Choi KC,Chan MT

更新日期：2008-02-01 00:00:00