The effects of glycopyrrolate on oral mucous host defenses in healthy volunteers.

abstract：:Alfentanil causes cardiac stimulation or depression in intact animals and in clinical practice; there is no information concerning its direct effects on the heart. Therefore, we studied the effects of alfentanil on isolated cardiac tissues from young adult rabbits. The right atrium with sinoatrial node (SA node) was b...

journal_title：Anesthesia and analgesia

authors： Zhang CC,Su JY,Calkins D

更新日期：1990-09-01 00:00:00

abstract：UNLABELLED:We used a double-blind design to study urodynamic changes induced by mu-agonists (fentanyl, morphine), a partial mu-agonist antagonist (buprenorphine), a putative mu-antagonist, kappa-agonist (nalbuphine), and ketoprofen, an injectable nonsteroidal antiinflammatory drug. Men (20-55 yr old) were randomly assi...

journal_title：Anesthesia and analgesia

authors： Malinovsky JM,Le Normand L,Lepage JY,Malinge M,Cozian A,Pinaud M,Buzelin JM

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Cigarette smoking by surgical patients is associated with increased complications, particularly perioperative respiratory problems and poor wound healing. In this study, we sought to determine whether a pragmatic perioperative smoking cessation intervention designed for a busy preadmission clinic would be su...

journal_title：Anesthesia and analgesia

authors： Lee SM,Landry J,Jones PM,Buhrmann O,Morley-Forster P

更新日期：2013-09-01 00:00:00

abstract：:Two hundred twenty-two spinal anesthesias were administered with 10 mg. of tetracaine and 1 ml. of 10 percent dextrose to investigate the effects of vasopressors, patients age, and pH of cerebrospinal fluid on the onset and duration of spinal anesthesia. Neither the differences in overall age, cerebrospinal fluid pH, ...

journal_title：Anesthesia and analgesia

authors： Park WY,Balingit PE,Macnamara TE

更新日期：1975-07-01 00:00:00

abstract：UNLABELLED:Adjuncts to local anesthetics for peripheral plexus blockade may enhance the quality and duration of anesthesia and postoperative analgesia. The analgesic, tramadol, has a unique mechanism of action that suggests efficacy as such an adjunct. It displays a central analgesic and peripheral local anesthetic eff...

journal_title：Anesthesia and analgesia

authors： Robaux S,Blunt C,Viel E,Cuvillon P,Nouguier P,Dautel G,Boileau S,Girard F,Bouaziz H

更新日期：2004-04-01 00:00:00

abstract：UNLABELLED:We performed this study to assess the safety of immediate extubation after elective abdominal aortic aneurysm surgery. Consecutive patients were prospectively randomized into two groups after surgery: Group 1 (n = 29) immediate extubation; and Group 2 (n = 21) delayed (at least 4 h) extubation. All patients ...

journal_title：Anesthesia and analgesia

authors： Cohen J,Loewinger J,Hutin K,Sulkes J,Zelikovski A,Singer P

更新日期：2001-12-01 00:00:00

abstract：:Lidocaine and MgSO4 are often coadministered to patients with pregnancy-induced hypertension. This study examined whether MgSO4 alters the lidocaine-seizure threshold in the rat and, if so, whether systemic MgSO4 administration is as effective as intracerebroventricular MgSO4 infusion. In Experiment 1, rats were admin...

journal_title：Anesthesia and analgesia

authors： Kim YJ,McFarlane C,Warner DS,Baker MT,Choi WW,Dexter F

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Music reduces stress responses in awake subjects. However, there remains controversy about the role of music or therapeutic suggestions during general anesthesia and postoperative recovery. We thus tested the hypothesis that intraoperative exposure to soothing music reduces the end-tidal concentration of sev...

journal_title：Anesthesia and analgesia

authors： Szmuk P,Aroyo N,Ezri T,Muzikant G,Weisenberg M,Sessler DI

更新日期：2008-07-01 00:00:00

abstract：UNLABELLED:Patients undergoing vascular surgery have a high risk of suffering major postoperative cardiac events. Preoperative myocardial ischemia as detected by Holter monitoring identifies a high-risk subgroup whose postoperative ischemia, similarly detected, seems to herald major cardiac events. In this study, we de...

journal_title：Anesthesia and analgesia

authors： Raby KE,Brull SJ,Timimi F,Akhtar S,Rosenbaum S,Naimi C,Whittemore AD

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Pulse wave analysis (PWA) allows cardiac output (CO) measurement after calibration by transpulmonary thermodilution. A PWA system that does not require previous calibration, the FloTrac/Vigileo (FTV), has been recently developed. We compared determinations of CO made with the FTV to simultaneous measurements...

journal_title：Anesthesia and analgesia

authors： Concha MR,Mertz VF,Cortínez LI,González KA,Butte JM

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Bupivacaine and ropivacaine are the preferred long-acting local anesthetics for peripheral nerve blocks as they provide prolonged analgesia in the postoperative period. No studies have directly compared the analgesic duration of these commonly used local anesthetics in the setting of low-volume ultrasound-gu...

journal_title：Anesthesia and analgesia

authors： Safa B,Flynn B,McHardy PG,Kiss A,Haslam L,Henry PD,Kaustov L,Choi S

更新日期：2021-01-15 00:00:00

abstract：:In a randomized study, we evaluated lag time (time from the end of injection of muscle relaxant until the first depression of the train-of-four response [TOF]), onset time (time from the end of injection of muscle relaxant until the maximum depression of the first twitch of the TOF [T1]), neuromuscular block, and endo...

journal_title：Anesthesia and analgesia

authors： Wierda JM,van den Broek L,Proost JH,Verbaan BW,Hennis PJ

更新日期：1993-09-01 00:00:00

abstract：:Procaine hydrochloride was added to cardioplegia and studied for its efficacy in stabilizing the postischemic rhythm after aortic declamping in cardiac surgery. Fifty-six patients scheduled for coronary artery bypass grafting (CABG), were included in a randomized, double-blind study. The patients were anesthetized wit...

journal_title：Anesthesia and analgesia

authors： Sellevold OF,Berg EM,Levang OW

更新日期：1995-11-01 00:00:00

abstract：:This study was conducted to assess the learning function of murine progeny born of mothers that had received either 1% or 2% halothane or 2% or 4% enflurane, on days 6 and 10 or days 14 and 17 or gestation. Their timed performance at the age of 6 to 7 weeks was compared in a maze with that of control mice of similar a...

journal_title：Anesthesia and analgesia

authors： Chalon J,Tang CK,Ramanathan S,Eisner M,Katz R,Turndorf H

更新日期：1981-11-01 00:00:00

abstract：:Nitrous oxide increases peripheral vascular tone in animals and humans and constricts epicardial coronary arteries in dogs. Current studies sought both to determine whether nitrous oxide caused epicardial coronary artery constriction in a second animal species, pigs, and to investigate mechanisms. Left anterior descen...

journal_title：Anesthesia and analgesia

authors： Hughes JM,Sill JC,Pettis M,Rorie DK

更新日期：1993-08-01 00:00:00

abstract：:We determined the cardiovascular effects of 0.91, 1.34, and 1.74 MAC of desflurane/nitrous oxide anesthesia (60% inspired nitrous oxide contributed 0.5 MAC at each level) in 12 healthy, normocapnic male volunteers. Desflurane/nitrous oxide anesthesia decreased systemic blood pressures, cardiac index, stroke volume ind...

journal_title：Anesthesia and analgesia

authors： Cahalan MK,Weiskopf RB,Eger EI 2nd,Yasuda N,Ionescu P,Rampil IJ,Lockhart SH,Freire B,Peterson NA

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Volatile inhaled anesthetics exert a differential protective effect against bronchospasm development after cholinergic stimulation. However, their ability to inhibit the adverse respiratory consequences of an anaphylactic reaction after exposure to an allergen has not been characterized. We therefore compare...

journal_title：Anesthesia and analgesia

authors： Lele E,Petak F,Carnesecchi S,Virag K,Argiroffo CB,Habre W

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:District-level hospitals (DLHs) are the main providers of surgical services for rural populations in Sub-Saharan Africa (SSA). Skilled teams are essential for surgical care, and gaps in anesthesia impact negatively on surgical capacity and outcomes. This study, from a baseline of a project scaling-up access ...

journal_title：Anesthesia and analgesia

authors： Gajewski J,Pittalis C,Lavy C,Borgstein E,Bijlmakers L,Mwapasa G,Cheelo M,Le G,Juma A,Kachimba J,Marealle P,Mkandawire N,Chilonga K,Brugha R

更新日期：2020-04-01 00:00:00

abstract：:Colloids and crystalloids are usually administered as treatment for hypovolemia in severely injured patients. However, dilution of clotting factors and platelets together with impaired fibrinogen polymerization are associated with fluid therapy and may aggravate hemorrhage, thus worsening final outcome of these patien...

journal_title：Anesthesia and analgesia

authors： Fries D,Innerhofer P,Reif C,Streif W,Klingler A,Schobersberger W,Velik-Salchner C,Friesenecker B

更新日期：2006-02-01 00:00:00

abstract：:Because deviations from the Meyer-Overton rule may provide insights into the attributes of the anesthetic site of action, we characterized the solubility of the n-alkanes in various hydrophobic solvents (n-tetradecane, olive oil, n-octanol, and lecithin) as well as saline using variations on standard techniques. Incre...

journal_title：Anesthesia and analgesia

authors： Taheri S,Laster MJ,Liu J,Eger EI 2nd,Halsey MJ,Koblin DD

更新日期：1993-07-01 00:00:00

abstract：:We describe the treatment of two patients with hemorrhagic shock unresponsive to volume replacement and catecholamines. Both patients responded to a small-dose infusion of vasopressin, which allowed tapering off of the catecholamines. The possible role of small-dose infusions of vasopressin in fluid- and catecholamine...

journal_title：Anesthesia and analgesia

authors： Sharma RM,Setlur R

更新日期：2005-09-01 00:00:00

abstract：:The onset and intensity of blockade of the lumbosacral dermatomes after epidural anesthesia with alkalinized lidocaine were investigated in a randomized, double-blind study in 26 patients. Control subjects (n = 13) received 20 mL of 1.37% lidocaine (1.5% lidocaine plus 1 mL saline per 10 mL lidocaine) with added 1:200...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Toleikis JR,Dixit P,Goodman I,Hill JA

更新日期：1993-02-01 00:00:00

abstract：IMPLICATIONS:Esophageal insufflation can occur simultaneously with venting from the drain tube during positive pressure ventilation with the ProSeal laryngeal mask airway. ...

journal_title：Anesthesia and analgesia

authors： Stix MS,Borromeo CJ,O'Connor CJ Jr

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:We determined whether whole blood impedance aggregometry using the Multiplate detects the effects of antiplatelet drugs as reliably as does classical light transmission aggregometry (LTA) or the platelet function analyzer PFA-100(R). METHODS:Multiplate (M) assays, measuring changes in electrical resistance ...

journal_title：Anesthesia and analgesia

authors： Velik-Salchner C,Maier S,Innerhofer P,Streif W,Klingler A,Kolbitsch C,Fries D

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:In patients undergoing total knee arthroplasty under spinal anesthesia, we compared the postoperative analgesic effect of intraoperative sedation with dexmedetomidine versus propofol. We hypothesized that sedation with dexmedetomidine would result in lower postoperative opioid analgesic consumption than with...

journal_title：Anesthesia and analgesia

authors： Shin HJ,Do SH,Lee JS,Kim TK,Na HS

更新日期：2019-12-01 00:00:00

abstract：UNLABELLED:Postoperative pain management after cardiac surgery has been mainly based on parenteral opioids. However, because opioids have numerous side effects, coadministration of non-opioid analgesics has been introduced as a method of reducing opioid dose. In this prospective, randomized, double-blinded study, we ev...

journal_title：Anesthesia and analgesia

authors： Lahtinen P,Kokki H,Hendolin H,Hakala T,Hynynen M

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Continuous femoral analgesia provides extended pain relief and improved functional recovery for total knee arthroplasty (TKA). Stimulating catheters may allow more accurate placement of catheters. METHODS:We performed a randomized prospective study to investigate the use of stimulating catheters versus nons...

journal_title：Anesthesia and analgesia

authors： Hayek SM,Ritchey RM,Sessler D,Helfand R,Samuel S,Xu M,Beven M,Bourdakos D,Barsoum W,Brooks P

更新日期：2006-12-01 00:00:00

abstract：:Epidural clonidine produces analgesia in humans with acute and chronic pain. Its use is limited because of short-lasting analgesia, hemodynamic depression, sedation, and respiratory depression. Intrathecal guanfacine has a longer duration of action than intrathecal clonidine. The present study compares these two drugs...

journal_title：Anesthesia and analgesia

authors： Smith BD,Baudendistel LJ,Gibbons JJ,Schweiss JF

更新日期：1992-05-01 00:00:00

abstract：:Two concentrations of etidocaine (1 and 1.5%) and of pH-adjusted bupivacaine (0.5 and 0.75%, pH 6.8), all fortified with hyaluronidase, were compared as local anesthetics in regional ophthalmic surgery for cataract extraction. The series comprised 160 patients assigned randomly to four groups (n = 40). Each patient re...

journal_title：Anesthesia and analgesia

authors： Sarvela PJ

更新日期：1993-07-01 00:00:00

abstract：UNLABELLED:N-methyl-D-aspartate (NMDA) antagonists, such as MK801, delay the development of morphine tolerance. Magnesium, a noncompetitive NMDA antagonist, reduces postoperative morphine requirements. The present study was designed to evaluate the effects of intrathecal co-administration of magnesium sulfate with morp...

journal_title：Anesthesia and analgesia

authors： McCarthy RJ,Kroin JS,Tuman KJ,Penn RD,Ivankovich AD

更新日期：1998-04-01 00:00:00