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Listening to music during anesthesia does not reduce the sevoflurane concentration needed to maintain a constant bispectral index.

Abstract：

BACKGROUND:Music reduces stress responses in awake subjects. However, there remains controversy about the role of music or therapeutic suggestions during general anesthesia and postoperative recovery. We thus tested the hypothesis that intraoperative exposure to soothing music reduces the end-tidal concentration of sevoflurane (ETSevo) necessary to maintain bispectral index (BIS) near 50 during laparoscopic surgery. METHODS:Forty patients, aged 40-60 yrs, ASA I and II, undergoing laparoscopic hernias or cholecystectomy under general anesthesia were studied. All patients were connected to a BIS monitor. Anesthesia was induced with fentanyl 2 microg/kg, sevoflurane in oxygen, rocuronium (0.6 mg/kg), and maintained with sevoflurane in oxygen and 50% nitrous oxide, with an infusion of fentanyl (1 microg x kg(-1) x h(-1)). Sevoflurane was titrated to maintain BIS near 50 throughout the procedure. Patients were randomly assigned to either listen to music or not. RESULTS:The ETSevo necessary to maintain a BIS near 50 was virtually identical in patients who listened to music (1.29 +/- 0.33%) and those who did not (1.27 +/- 0.33%, P = 0.84). Patients who listened to music reported slightly less pain, but the difference was not statistically significant. Mean arterial blood pressure was slightly higher in patients who listened to music (101 +/- 11 mm Hg) than in those who did not (94 +/- 10 mm Hg, P = 0.040). CONCLUSIONS:The end-tidal concentration of sevoflurane required to maintain BIS near 50 during laparoscopic cholecystectomy was virtually identical in patients exposed to music or not. Although previous work suggests that music reduces preoperative stress and may be useful during sedation, our results do not support the use of music during surgery.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Szmuk P,Aroyo N,Ezri T,Muzikant G,Weisenberg M,Sessler DI

doi

10.1213/ane.0b013e3181733e16

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

77-80

issue

eissn

0003-2999

issn

1526-7598

pii

107/1/77

journal_volume

107

pub_type

杂志文章,随机对照试验

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Listening to music during anesthesia does not reduce the sevoflurane concentration needed to maintain a constant bispectral index.