The effect of fibrinogen substitution on reversal of dilutional coagulopathy: an in vitro model.

abstract：:The anesthetic propofol (2,6 diisopropylphenol) mediates some of its effects by activating inhibitory chloride currents in the lower brainstem and spinal cord. The effects comprise direct activation of gamma-aminobutyric acid-A and glycine receptors in the absence of the natural agonist, as well as potentiation of the...

journal_title：Anesthesia and analgesia

authors： Ahrens J,Haeseler G,Leuwer M,Mohammadi B,Krampfl K,Dengler R,Bufler J

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:In 2001, the Center for Medicare and Medicaid Services issued a rule permitting states to "opt-out" of federal regulations requiring physician supervision of nurse anesthetists. We examined the extent to which this rule increased access to anesthesia care for urgent cases. METHODS:Using data from a national...

journal_title：Anesthesia and analgesia

authors： Sun E,Dexter F,Miller TR

更新日期：2016-06-01 00:00:00

abstract：:The original 1858 edition of John Snow's On Chloroform and Other Anaesthetics, from which came the Wood Library-Museum of Anesthesiology reprints in 1971 and 1989, was donated to the Wood Library-Museum by Ralph Waters of Madison, Wisconsin, in 1967. The book contains a message of appreciation to Waters, dated October...

journal_title：Anesthesia and analgesia

authors： Maltby JR,Bamforth BJ

更新日期：1990-09-01 00:00:00

abstract：:Computer simulations for the technique of estimating minimum alveolar anesthetic concentration (MAC) in patients (quantal design) suggest that incremental concentration changes and the number of crossovers affect MAC. We hypothesized that these variables may also apply to estimating MAC in rats (bracketing design). Th...

journal_title：Anesthesia and analgesia

authors： Leon A,Mayzler O,Benifla M,Semionov M,Fuxman Y,Eilig I,Passuga V,Doitchinova MK,Gurevich B,Artru AA,Shapira Y

更新日期：2004-12-01 00:00:00

abstract：:The purpose of this study was to compare the psychological effects of ketamine and thiopental anesthesia. In a double-blind comparison, 20 normal female volunteers were given 2.5 mg/kg ketamine intravenously and 20 were given 5.0 mg/kg thiopental intravenously. Subjects were assessed with a variety of objective and su...

journal_title：Anesthesia and analgesia

authors： Moretti RJ,Hassan SZ,Goodman LI,Meltzer HY

更新日期：1984-12-01 00:00:00

abstract：:The effect of enflurane anesthesia on bronchomotor tone was studied in 15 dogs, using isolated tracheal segments in situ. In six animals, the changes of tracheal tension in response to changing enflurane concentration were continuously measured while keeping tidal volume, respiratory frequency, and end-tidal PCO2 cons...

journal_title：Anesthesia and analgesia

authors： Kochi T,Hagiya M,Mizuguchi T

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Asian American/Pacific Islanders (AAPIs) are the fastest-growing racial group in the United States. Despite a higher socioeconomic status, AAPI women experience higher rates of maternal morbidity and mortality. METHODS:Using the National Inpatient Sample, we performed a retrospective cohort analysis of wome...

journal_title：Anesthesia and analgesia

authors： Siddiqui M,Minhaj M,Mueller A,Tung A,Scavone B,Rana S,Shahul S

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:We tested the hypothesis that inhibition of cyclooxygenase (COX) attenuates in vivo ventilator-induced lung injury (VILI) in a prospective, randomized laboratory investigation in a university-affiliated laboratory. Adult male rats were anesthetized and randomized with or without nonselective COX inhibition (...

journal_title：Anesthesia and analgesia

authors： Niitsu T,Tsuchida S,Peltekova V,Engelberts D,Copland I,Otulakowski G,Post M,Kavanagh BP

更新日期：2011-01-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：:A study of the effects of halothane on the cyclic 3',5'-adenosine monophosphate (cAMP) system in human platelets was undertaken since cAMP has been implicated in the regulation of the process of platelet aggregation and this anesthetic has been reported to decrease platelet aggregation and, in other tissues, to increa...

journal_title：Anesthesia and analgesia

authors： Walter F,Vulliemoz Y,Verosky Y,Triner L

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:The α2-adrenergic agonist dexmedetomidine is a sedative and can be used as an adjunct to anesthetics. Our primary goal was thus to determine the extent to which dexmedetomidine reduces the requirement for propofol and remifentanil. METHODS:This double-blinded, randomized study (NCT00921284) used an automate...

journal_title：Anesthesia and analgesia

authors： Le Guen M,Liu N,Tounou F,Augé M,Tuil O,Chazot T,Dardelle D,Laloë PA,Bonnet F,Sessler DI,Fischler M

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Anesthesiologists may contribute to postoperative infections by means of the transmission of blood and pathogens to the patient and the environment in the operating room (OR). Our primary aims were to determine whether contamination of the IV hub, the anesthesia work area, and the patient could be reduced af...

journal_title：Anesthesia and analgesia

authors： Birnbach DJ,Rosen LF,Fitzpatrick M,Carling P,Arheart KL,Munoz-Price LS

更新日期：2015-11-01 00:00:00

abstract：UNLABELLED:We studied lung function in children with and without asthma receiving anesthesia with sevoflurane. Fifty-two children had anesthesia induced with sevoflurane (up to 8%) in a mixture of 50% nitrous oxide in oxygen and then maintained at 3% with children breathing spontaneously via face mask and Jackson-Rees ...

journal_title：Anesthesia and analgesia

authors： Habre W,Scalfaro P,Sims C,Tiller K,Sly PD

更新日期：1999-11-01 00:00:00

abstract：:The present investigation explored the possibility that the commonly observed hypotension that occurs during induction of anesthesia with propofol might be related to its ability to produce venodilation. Thirty-six ASA I and II patients who received no premedication were studied. The first 20 patients were divided int...

journal_title：Anesthesia and analgesia

authors： Muzi M,Berens RA,Kampine JP,Ebert TJ

更新日期：1992-06-01 00:00:00

abstract：UNLABELLED:Patients who are approached to participate in clinical studies just before delivery may have insufficient time to make an informed decision and/or may feel pressured into participation. This study was designed to examine factors that influence parturients to consent or decline participation in an anesthesia ...

journal_title：Anesthesia and analgesia

authors： Dorantes DM,Tait AR,Naughton NN

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:There have been numerous studies published on the ProSeal laryngeal mask airway (PLMA). However, few have investigated its utility in a large practice setting. We sought to gather comprehensive data about the characteristics, efficacy, and safety of its use by a representative group of anesthesiologists work...

journal_title：Anesthesia and analgesia

authors： Goldmann K,Hechtfischer C,Malik A,Kussin A,Freisburger C

更新日期：2008-12-01 00:00:00

abstract：UNLABELLED:In the present study, we investigated the effect of remifentanil on cerebral blood flow velocity (CBFV). We investigated 20 patients (ASA physical status III) scheduled for elective coronary artery bypass graft surgery. Anesthesia was induced with remifentanil 5 microg/kg IV (Group 1, n = 10) or 2 microg/kg ...

journal_title：Anesthesia and analgesia

authors： Paris A,Scholz J,von Knobelsdorff G,Tonner PH,Schulte am Esch J

更新日期：1998-09-01 00:00:00

abstract：:The swallowing reflex is depressed by anesthetics. During recovery from anesthesia the rapid return of laryngeal and upper airway reflexes is important to protect the lower airway from aspiration. This study measures the recovery of the swallowing reflex after propofol anesthesia. Fifteen patients undergoing a colonos...

journal_title：Anesthesia and analgesia

authors： Rimaniol JM,D'Honneur G,Duvaldestin P

更新日期：1994-11-01 00:00:00

abstract：:The purpose of this study was to determine the analgesic efficacy, opioid-sparing effect, and tolerability of ketorolac administered as an intravenous (i.v.) bolus followed by a continuous infusion after total hip or knee arthroplasty. After general anesthesia, patients received either placebo or ketorolac 30 mg i.v. ...

journal_title：Anesthesia and analgesia

authors： Etches RC,Warriner CB,Badner N,Buckley DN,Beattie WS,Chan VW,Parsons D,Girard M

更新日期：1995-12-01 00:00:00

abstract：:Several federal agencies have recently noted that the United States is in the midst of an unprecedented "opioid epidemic," with an increasing number of opioid-related overdoses and deaths. Providers currently face 3 population-level, public health challenges in providing optimal perioperative pain care: (1) the contin...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Kain ZN

更新日期：2017-11-01 00:00:00

abstract：:The charts of 1553 patients who were anesthetized for ambulatory surgery were analyzed retrospectively to determine the effect of the type of surgery, the age of the patient, the use of premedication, the duration of anesthesia, and the anesthetic technique on the duration of recovery and the rate of complications. In...

journal_title：Anesthesia and analgesia

authors： Meridy HW

更新日期：1982-11-01 00:00:00

abstract：:Experimental aspiration pneumonitis studies in general have focused on the pathogenesis of the acidic component of the lung injury, although the injury produced by the particulate component of gastric contents largely has been ignored. The present study compares the inflammatory potential of small gastric particles to...

journal_title：Anesthesia and analgesia

authors： Knight PR,Rutter T,Tait AR,Coleman E,Johnson K

更新日期：1993-10-01 00:00:00

abstract：:Drug dosages, length of stay (LOS), and incidence of psychological side effects of fentanyl and nalbuphine were compared in a randomized, double-blind study using unpremedicated female day-surgery patients undergoing diagnostic laparoscopy. Patients received either fentanyl 1.5 micrograms/kg (F group; n = 142), low-do...

journal_title：Anesthesia and analgesia

authors： Garfield JM,Garfield FB,Philip BK,Earls F,Roaf E

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:The arterial pulse oximeter, which was introduced clinically in the 1970s, is a convenient, useful, and now ubiquitous anesthesia monitor. Unfortunately, although percent saturation of arterial hemoglobin is, along with cardiac output and concentration of hemoglobin, one of 3 components of oxygen delivery, i...

journal_title：Anesthesia and analgesia

authors： Thiele RH,Tucker-Schwartz JM,Lu Y,Gillies GT,Durieux ME

更新日期：2011-06-01 00:00:00

abstract：UNLABELLED:We selected bis [N-(3,4-diacetoxybenzyl) tropanium-3alpha-yl] glutarate dibromide (TAAC3) from many new tropinyl diester derivatives to evaluate its neuromuscular blocking (NMB) and autonomic side effects on anesthetized rats, rabbits, guinea pigs, cats, pigs, dogs, and monkeys. NMB potency, onset, recovery ...

journal_title：Anesthesia and analgesia

authors： Gyermek L,Lee C,Cho YM,Nguyen N,Tsai SK

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Midazolam is the most commonly used premedication in children. It has been shown to be more effective than parental presence or placebo in reducing anxiety and improving compliance at induction of anesthesia. Clonidine, an alpha(2) agonist, has been suggested as an alternative. Dexmedetomidine is a more alph...

journal_title：Anesthesia and analgesia

authors： Yuen VM,Hui TW,Irwin MG,Yuen MK

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The switch from International Classification of Diseases, Ninth Revision, Clinical Modification to International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) for coding of inpatient procedures in the United States increased the number of procedural codes more than 19-fold,...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,O'Neill L

更新日期：2019-06-01 00:00:00

abstract：UNLABELLED:Sudden profound hypotensive and/or bradycardic events (HBE) have been reported in >20% of patients undergoing shoulder arthroscopy in the sitting position under interscalene block anesthesia. Retrospective studies suggest that the administration of beta-blockers is safe and may decrease the incidence of thes...

journal_title：Anesthesia and analgesia

authors： Liguori GA,Kahn RL,Gordon J,Gordon MA,Urban MK

更新日期：1998-12-01 00:00:00

abstract：:This study was performed to compare the efficacy of tropisetron, droperidol, and saline in the prevention of postoperative nausea and vomiting (PONV) and to compare the possible adverse effects of these drugs in gynecologic incontinence surgery. Using a randomized, double-blind study design, we studied 150 women under...

journal_title：Anesthesia and analgesia

authors： Purhonen S,Kauko M,Koski EM,Nuutinen L

更新日期：1997-03-01 00:00:00

abstract：:A new single injection procedure, the fascia iliaca compartment block, is described for blocking the femoral, lateral cutaneous, and obturator nerves. The technique consists of injecting a local anesthetic immediately behind the fascia iliaca at the union of the lateral with the two medial thirds of the inguinal ligam...

journal_title：Anesthesia and analgesia

authors： Dalens B,Vanneuville G,Tanguy A

更新日期：1989-12-01 00:00:00