The Wood Library-Museum's 1858 edition of John Snow's On chloroform and other anaesthetics.

abstract：:Aging and disease may make the elderly patient with cardiac disease particularly susceptible to hypotension during spinal anesthesia. We studied 15 men, 59-80 y old, with histories of prior myocardial infarction (n = 9), congestive heart failure (n = 2), and/or stable myocardial ischemia (n = 11) given spinal anesthes...

journal_title：Anesthesia and analgesia

authors： Rooke GA,Freund PR,Jacobson AF

更新日期：1997-07-01 00:00:00

abstract：:Patients with coronavirus disease 2019 (COVID-19) frequently experience a coagulopathy associated with a high incidence of thrombotic events leading to poor outcomes. Here, biomarkers of coagulation (such as D-dimer, fibrinogen, platelet count), inflammation (such as interleukin-6), and immunity (such as lymphocyte co...

journal_title：Anesthesia and analgesia

authors： Görlinger K,Dirkmann D,Gandhi A,Simioni P

更新日期：2020-11-01 00:00:00

abstract：UNLABELLED:We investigated the effects of isoflurane-induced burst suppression, monitored with electroencephalography (EEG), on cerebral blood flow velocity (CBFV), cerebral oxygen extraction (COE), and autoregulation in 16 patients undergoing cardiac surgery. The experimental procedure was performed during nonpulsatil...

journal_title：Anesthesia and analgesia

authors： Reinsfelt B,Westerlind A,Houltz E,Ederberg S,Elam M,Ricksten SE

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Whether intraoperative analgesics have an impact on postoperative cancer recurrence is unknown. Some investigations suggest that the opioids could favor relapse and that regional analgesia and nonsteroidal antiinflammatory drugs could improve cancer prognosis. We retrospectively reviewed our series of breast...

journal_title：Anesthesia and analgesia

authors： Forget P,Vandenhende J,Berliere M,Machiels JP,Nussbaum B,Legrand C,De Kock M

更新日期：2010-06-01 00:00:00

abstract：:Hypotensive effects of the intravenous injection of adenine compounds [adenosine triphosphate (ATP), adenosine] were compared with those of sodium nitroprusside (SNP) in rabbits during light, stable halothane anesthesia. ATP and adenosine were almost equipotent in their effects on blood pressure and heart rate. The hy...

journal_title：Anesthesia and analgesia

authors： Fukunaga AF,Flacke WE,Bloor BC

更新日期：1982-03-01 00:00:00

abstract：:The effects of ropivacaine, a new amide local anesthetic, on uterine blood flow and fetal well-being were compared with those of bupivacaine in 10 chronically instrumented pregnant ewes. In random sequence, animals received two intravenous infusions of each drug. The low infusion rate regimens were chosen to result in...

journal_title：Anesthesia and analgesia

authors： Santos AC,Arthur GR,Roberts DJ,Wlody D,Pedersen H,Morishima HO,Finster M,Covino BG

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Gabapentin is an adjuvant analgesic and may enhance the spread of subarachnoid block. We investigated the effects of pretreatment with gabapentin on subarachnoid block characteristics and hemodynamics. METHODS:Seventy patients undergoing transurethral procedures under subarachnoid anesthesia with 2.2 mL of ...

journal_title：Anesthesia and analgesia

authors： Fassoulaki A,Chatziara V,Melemeni A,Zotou M,Sarantopoulos C

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Inhibitors of cyclooxygenase, which block the formation of prostaglandin (PG) E2, are the standard treatment of inflammatory pain. These drugs, however, have serious gastrointestinal, renal, and cardiovascular side effects that limit their clinical use. Cyclodextrins are neutral glucose oligomers that form a...

journal_title：Anesthesia and analgesia

authors： Sauer RS,Rittner HL,Roewer N,Sohajda T,Shityakov S,Brack A,Broscheit JA

更新日期：2017-02-01 00:00:00

abstract：:An in-vitro experiment demonstrated the concentration effect of N2O (3% versus 75%) during elimination and during uptake. Other pulmonary absorption-excretion phenomena also occur simultaneously, as paired events during uptake and then during elimination:diffusion hyperoxia and diffusion anoxia; alveolar concentration...

journal_title：Anesthesia and analgesia

authors： Rackow H,Salanitre E

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Goal-directed fluid therapy (GDFT) is associated with improved outcomes after surgery. The esophageal Doppler monitor (EDM) is widely used, but has several limitations. The NICOM, a completely noninvasive cardiac output monitor (Cheetah Medical), may be appropriate for guiding GDFT. No prospective studies ha...

journal_title：Anesthesia and analgesia

authors： Waldron NH,Miller TE,Thacker JK,Manchester AK,White WD,Nardiello J,Elgasim MA,Moon RE,Gan TJ

更新日期：2014-05-01 00:00:00

abstract：UNLABELLED:In a randomized trial, we compared topical anesthesia by a lidocaine-prilocaine cream (EMLA; Laboratorie ASTRA, Manterre, France) with subcutaneous local lidocaine infiltration for radial artery cannulation. Patients included 538 adults scheduled for coronary angiography using a radial approach. EMLA was app...

journal_title：Anesthesia and analgesia

authors： Joly LM,Spaulding C,Monchi M,Ali OS,Weber S,Benhamou D

更新日期：1998-08-01 00:00:00

abstract：:Substance abuse is a potentially lethal occupational hazard confronting anesthesiology residents. We present the results of a survey sent to all United States anesthesiology training programs regarding experience with and outcomes of chemically dependent residents from 1991 to 2001. The response rate was 66%. Eighty p...

journal_title：Anesthesia and analgesia

authors： Collins GB,McAllister MS,Jensen M,Gooden TA

更新日期：2005-11-01 00:00:00

abstract：:The displacement of the larynx in the three specific directions (a) posteriorly against the cervical vertebrae, (b) superiorly as possible, and (c) slightly laterally to the right have been reported and named the "BURP" maneuver. We evaluated the efficacy of the BURP maneuver in improving visualization of the larynx. ...

journal_title：Anesthesia and analgesia

authors： Takahata O,Kubota M,Mamiya K,Akama Y,Nozaka T,Matsumoto H,Ogawa H

更新日期：1997-02-01 00:00:00

abstract：UNLABELLED:Using a MEDLINE-based analysis, we studied the national origin of articles published in important anesthesia, pain, critical care, and emergency medicine journals. All journals in English listed in the Science Citation Index (SCI) of Journal Citation Reports under the subheadings Anesthesiology (n = 17) and ...

journal_title：Anesthesia and analgesia

authors： Boldt J,Maleck W,Koetter KP

更新日期：1999-05-01 00:00:00

abstract：:Spontaneous or evoked electrical brain activity is increasingly used to monitor general anesthesia. Previous studies investigated the variables from spontaneous electroencephalogram (EEG), acoustic (AEP), or somatosensory evoked potentials (SSEP). But, by monitoring them separately, the available information from simu...

journal_title：Anesthesia and analgesia

authors： Jeleazcov C,Schneider G,Daunderer M,Scheller B,Schüttler J,Schwilden H

更新日期：2006-10-01 00:00:00

abstract：:The dose-dependent effects of nitrous oxide on thymidine and methionine syntheses were investigated in pregnant rats. Female Sprague-Dawley rats were exposed on day 9 of gestation to 0.75%, 7.5%, or 75% nitrous oxide for 24 h. Immediately and 72 h after exposure, a deoxyuridine-suppression test was performed on matern...

journal_title：Anesthesia and analgesia

authors： Baden JM,Rice SA,Serra M,Kelley M,Mazze R

更新日期：1983-08-01 00:00:00

abstract：:In a laboratory experiment, the expected analgesic action of 33% nitrous oxide was reversed by creating the expectancy of heightened awareness of bodily sensations. Pain threshold and tolerance of electrical tooth-pulp stimulation were significantly reduced. Results from a control study gave us a basis for comparison ...

journal_title：Anesthesia and analgesia

authors： Dworkin SF,Chen AC,LeResche L,Clark DW

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Previous modeling of the kinetics of uptake and elimination of anesthetic drugs from the site of action has used measures derived from the electroencephalogram. Such measures lag the current brain activity because of the time needed to acquire a signal sample and derive the measure. With a direct measure of ...

journal_title：Anesthesia and analgesia

authors： Drummond GB,Bleach L,Thomson AJ,Kennedy RR

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Previous studies show that the potent, prototypical sigma(1)-receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) prevents cell death after oxygen-glucose deprivation (OGD) in primary cortical neuronal cultures. We tested the hypothesis that PPBP protects neurons by a mechanism involving activation ...

journal_title：Anesthesia and analgesia

authors： Yang S,Alkayed NJ,Hurn PD,Kirsch JR

更新日期：2009-03-01 00:00:00

abstract：UNLABELLED:Patients may have concerns about their ability to manage postoperative symptoms at home after ambulatory surgery. We assessed patients' attitudes toward postoperative care at home or in the hospital after laparoscopic cholecystectomy. Thirty-eight patients undergoing elective laparoscopic cholecystectomy wer...

journal_title：Anesthesia and analgesia

authors： Lehmann HP,Fleisher LA,Lam J,Frink BA,Bass EB

更新日期：1999-06-01 00:00:00

abstract：:Calciphylaxis is a small-vessel disease associated with renal failure. Here, we report the management of a 43-yr-old man with calciphylaxis who received left lower leg amputation with prostaglandin E(1) (PGE(1)) under monitoring by laser Doppler blood flowmetry in the left second and third fingers. Anesthesia was indu...

journal_title：Anesthesia and analgesia

authors： Horishita T,Minami K,Ogata J,Sata T

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Manikins are widely used in airway management training; however, simulation of realism and interpatient variability remains a challenge. We investigated whether cadavers embalmed with the novel Fix for Life (F4L) embalmment method are a suitable and realistic model for teaching 3 basic airway skills: facemas...

journal_title：Anesthesia and analgesia

authors： van Emden MW,Geurts JJ,Schober P,Schwarte LA

更新日期：2018-10-01 00:00:00

abstract：:Fifteen critically ill patients with acute respiratory failure were ventilated with high-frequency jet ventilation (HFJV; frequency 100 breaths/min; I/E ratio 0.43; 1.8-mm internal diameter injector cannula). The patients were divided into two groups according to their initial PaO2 during intermittent positive pressur...

journal_title：Anesthesia and analgesia

authors： Benhamou D,Ecoffey C,Rouby JJ,Fusciardi J,Viars P

更新日期：1984-01-01 00:00:00

abstract：UNLABELLED:Evidence suggests that early postischemic hyperemia is mediated by both neurological and vascular mechanisms. We hypothesized that if neuronal activity were primarily responsible for reperfusion hyperemia, then electrocerebral silence induced by intracarotid anesthetics (propofol and pentothal) would attenua...

journal_title：Anesthesia and analgesia

authors： Joshi S,Wang M,Nishanian EV,Emerson RG

更新日期：2004-05-01 00:00:00

abstract：UNLABELLED:Controversy surrounds the use of the antiemetic droperidol, because of the Food and Drug Administration-imposed "black box" warning alleging that even small doses of the drug can lead to serious (even fatal) arrhythmias when it is used for antiemetic prophylaxis during the perioperative period. We used mathe...

journal_title：Anesthesia and analgesia

authors： Zhang Y,Luo Z,White PF

更新日期：2004-05-01 00:00:00

abstract：UNLABELLED:Heart transplantation in patients with increased pulmonary vascular resistance is often associated with postbypass right heart failure. We therefore compared the abilities of prostaglandin E(1) (PGE(1)) and inhaled nitric oxide to reduce pulmonary vascular resistance during heart transplantation. Patients un...

journal_title：Anesthesia and analgesia

authors： Rajek A,Pernerstorfer T,Kastner J,Mares P,Grabenwöger M,Sessler DI,Grubhofer G,Hiesmayr M

更新日期：2000-03-01 00:00:00

abstract：:We investigated the incidence of transient neurologic symptoms (TNS) after the use of hyperbaric lidocaine as compared with hyperbaric bupivacaine in patients undergoing cesarean delivery under spinal anesthesia. Two hundred women scheduled for cesarean delivery were randomly allocated to receive spinal anesthesia wit...

journal_title：Anesthesia and analgesia

authors： Aouad MT,Siddik SS,Jalbout MI,Baraka AS

更新日期：2001-02-01 00:00:00

abstract：:The effects of intravenously administered lidocaine on cough suppression in elderly patients over the age of 60 yr during tracheal intubation under general anesthesia were evaluated in two studies. In the first study, 100 patients received a placebo of either 0.5, 1.0, 1.5, or 2.0 mg/kg lidocaine intravenously 1 min b...

journal_title：Anesthesia and analgesia

authors： Yukioka H,Hayashi M,Terai T,Fujimori M

更新日期：1993-08-01 00:00:00

abstract：:During Gram-negative sepsis, endotoxin lipopolysaccharide (LPS) may activate host inflammatory responses, resulting in the systemic inflammatory response syndrome and the adult respiratory distress syndrome. In cell culture systems, LPS activation of cellular responses may be potentiated by plasma proteins. In the iso...

journal_title：Anesthesia and analgesia

authors： Goldsmith JA,Kavanagh BP,Pearl RG

更新日期：1996-08-01 00:00:00

abstract：:A low approach to the interscalene block (LISB) deposits local anesthetic farther caudad on the brachial plexus compared with the conventional interscalene block (ISB). We compared the efficacy of LISB and ISB in achieving anesthesia of the distal extremity in 254 patients having upper extremity surgery. The most freq...

journal_title：Anesthesia and analgesia

authors： Kim JH,Chen J,Bennett H,Lesser JB,Resta-Flarer F,Barczewska-Hillel A,Byrnes P,Santos AC

更新日期：2011-04-01 00:00:00