Anesthetic management of patients with severe peripheral ischemia due to calciphylaxis.

Abstract:

:Calciphylaxis is a small-vessel disease associated with renal failure. Here, we report the management of a 43-yr-old man with calciphylaxis who received left lower leg amputation with prostaglandin E(1) (PGE(1)) under monitoring by laser Doppler blood flowmetry in the left second and third fingers. Anesthesia was induced with midazolam, fentanyl, and vecuronium and was maintained with oxygen, nitrous oxide, and sevoflurane. The peripheral blood flow varied and decreased gradually; therefore, we added PGE(1) 20 ng. kg(-1). min(-1), which increased blood flow of the tissues. Three weeks after the operation, we again anesthetized the patient. We maintained the blood flow with PGE(1) throughout anesthesia. Monitoring by laser Doppler blood flowmetry and PGE(1) 20 ng. kg(-1). min(-1) could be useful for patients with impaired peripheral circulation, as in calciphylaxis.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Horishita T,Minami K,Ogata J,Sata T

doi

10.1213/01.ANE.0000121960.22554.D7

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

438-9, table of contents

issue

2

eissn

0003-2999

issn

1526-7598

pii

99/2/438

journal_volume

99

pub_type

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