Hemodynamic responses in brain dead organ donor patients.

Abstract:

:Because we have noticed dramatic hemodynamic responses in brain dead patients undergoing surgery for organ donation, we analyzed the anesthetic records of cadaver organ donors. Ten records contain complete data for heart rate, blood pressure, central venous pressure, and time of incision. Systolic pressure increased by a mean of 31 torr (P less than 0.01), diastolic pressure by 16 torr (P less than 0.02), and heart rate by 23 beats/min (P less than 0.01) in response to surgical stimulation. These results demonstrate the occurrence of significant hemodynamic responses to surgical stimuli in patients who fulfill the criteria of brain death, responses that do not, however, invalidate the current criteria for the diagnosis of brain death.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Wetzel RC,Setzer N,Stiff JL,Rogers MC

subject

Has Abstract

pub_date

1985-02-01 00:00:00

pages

125-8

issue

2

eissn

0003-2999

issn

1526-7598

journal_volume

64

pub_type

杂志文章
  • The inhibition of epidural morphine-induced pruritus by epidural droperidol.

    abstract:UNLABELLED:IV droperidol inhibits epidural morphine-induced pruritus, but this effect disappears when the dose is increased from 2.5 to 5.0 mg. This study was performed to determine whether epidural droperidol would have a similar effect. In this double-blinded study, we enrolled 140 patients undergoing Cesarean delive...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200003000-00025

    authors: Horta ML,Ramos L,Gonçalves ZR

    更新日期:2000-03-01 00:00:00

  • Mivacurium and bronchospasm.

    abstract:IMPLICATIONS:Because of case reports of severe bronchospasm after the use of mivacurium, we used the Food and Drug Administration MedWatch database to determine the frequency of bronchospasm as an adverse event after the use of nondepolarizing muscle relaxants. ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000067433.05538.3d

    authors: Bishop MJ,O'Donnell JT,Salemi JR

    更新日期:2003-08-01 00:00:00

  • Do new anesthesia ventilators deliver small tidal volumes accurately during volume-controlled ventilation?

    abstract:BACKGROUND:During mechanical ventilation of infants and neonates, small changes in tidal volume may lead to hypo- or hyperventilation, barotrauma, or volutrauma. Partly because breathing circuit compliance and fresh gas flow affect tidal volume delivery by traditional anesthesia ventilators in volume-controlled ventila...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e31816a68c6

    authors: Bachiller PR,McDonough JM,Feldman JM

    更新日期:2008-05-01 00:00:00

  • Electronic Audit and Feedback With Positive Rewards Improve Anesthesia Provider Compliance With a Barcode-Based Drug Safety System.

    abstract:BACKGROUND:We implemented a previously described barcode-based drug safety system in all of our anesthetizing locations. Providers were instructed to scan the barcode on syringes using our Anesthesia Information Management System before drug administration, but the rate of provider adherence was low. We studied an impl...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000003861

    authors: Bowdle TA,Jelacic S,Nair B,Zucker F,Bussey LS,Togashi K,Yang JT,Lang J

    更新日期:2019-08-01 00:00:00

  • Review articles: postoperative delirium: acute change with long-term implications.

    abstract::Delirium is an acute change in cognition and attention, which may include alterations in consciousness and disorganized thinking. Although delirium may affect any age group, it is most common in older patients, especially those with preexisting cognitive impairment. Patients with delirium after surgery recover more sl...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:10.1213/ANE.0b013e3182147f6d

    authors: Rudolph JL,Marcantonio ER

    更新日期:2011-05-01 00:00:00

  • Procoagulant activity in hemostasis and thrombosis: Virchow's triad revisited.

    abstract::Virchow's triad is traditionally invoked to explain pathophysiologic mechanisms leading to thrombosis, alleging concerted roles for abnormalities in blood composition, vessel wall components, and blood flow in the development of arterial and venous thrombosis. Given the tissue-specific bleeding observed in hemophilia ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:10.1213/ANE.0b013e31823a088c

    authors: Wolberg AS,Aleman MM,Leiderman K,Machlus KR

    更新日期:2012-02-01 00:00:00

  • Hyperglycemia impairs isoflurane-induced adenosine triphosphate-sensitive potassium channel activation in vascular smooth muscle cells.

    abstract:BACKGROUND:Isoflurane activates vascular adenosine triphosphate sensitive potassium (K(ATP)) channels, and may induce vasodilation. In the present study, we investigated whether hyperglycemia modifies isoflurane activation of vascular K(ATP) channel. METHODS:We used a cell-attached patch-clamp configuration to test th...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e318163fd5b

    authors: Kawano T,Tanaka K,Mawatari K,Oshita S,Takahashi A,Nakaya Y

    更新日期:2008-03-01 00:00:00

  • A Contemporary Medicolegal Analysis of Outpatient Medication Management in Chronic Pain.

    abstract:BACKGROUND:Opioids are frequently used in chronic pain management but are associated with significant morbidity and mortality in some patient populations. An important avenue for identifying complications-including serious or rare complications-is the study of closed malpractice claims. The present study is intended to...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000002499

    authors: Abrecht CR,Brovman EY,Greenberg P,Song E,Rathmell JP,Urman RD

    更新日期:2017-11-01 00:00:00

  • Comparison of desflurane with propofol in outpatients undergoing peripheral orthopedic surgery.

    abstract::This study was undertaken to compare desflurane with propofol anesthesia in outpatients undergoing peripheral orthopedic surgery. Data were combined from two institutions participating in a multicenter study. Ninety-one patients, ASA physical status I or II, were each randomly assigned to one of four groups. After adm...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/00000539-199210000-00019

    authors: Rapp SE,Conahan TJ,Pavlin DJ,Levy WJ,Hautman B,Lecky J,Luke J,Nessly ML

    更新日期:1992-10-01 00:00:00

  • Intrathecal versus intravenous fentanyl for supplementation of subarachnoid block during cesarean delivery.

    abstract:UNLABELLED:Forty-eight healthy parturients scheduled for elective cesarean delivery were randomly allocated to receive intrathecally either 12 mg of hyperbaric bupivacaine plus 12.5 microg of fentanyl (n = 23) or bupivacaine alone (n = 25). In the latter group, IV 12.5 microg of fentanyl was administered immediately af...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200207000-00037

    authors: Siddik-Sayyid SM,Aouad MT,Jalbout MI,Zalaket MI,Berzina CE,Baraka AS

    更新日期:2002-07-01 00:00:00

  • Exposure to halothane and enflurane affects learning function of murine progeny.

    abstract::This study was conducted to assess the learning function of murine progeny born of mothers that had received either 1% or 2% halothane or 2% or 4% enflurane, on days 6 and 10 or days 14 and 17 or gestation. Their timed performance at the age of 6 to 7 weeks was compared in a maze with that of control mice of similar a...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Chalon J,Tang CK,Ramanathan S,Eisner M,Katz R,Turndorf H

    更新日期:1981-11-01 00:00:00

  • Carbon Dioxide Absorption During Inhalation Anesthesia: A Modern Practice.

    abstract::CO2 absorbents were introduced into anesthesia practice in 1924 and are essential when using a circle system to minimize waste by reducing fresh gas flow to allow exhaled anesthetic agents to be rebreathed. For many years, absorbent formulations consisted of calcium hydroxide combined with strong bases like sodium and...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000005137

    authors: Feldman JM,Hendrickx J,Kennedy RR

    更新日期:2020-09-14 00:00:00

  • The effect of hospital size and surgical service on case cancellation in elective surgery: results from a prospective multicenter study.

    abstract:BACKGROUND:Short-term case cancellation causes frustration for anesthesiologists, surgeons, and patients and leads to suboptimal use of operating room (OR) resources. In many facilities, >10% of all cases are cancelled on the day of surgery, thereby causing major problems for OR management and anesthesia departments. T...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,多中心研究

    doi:10.1213/ANE.0b013e318222be4d

    authors: Schuster M,Neumann C,Neumann K,Braun J,Geldner G,Martin J,Spies C,Bauer M,CASCAES Study Group.

    更新日期:2011-09-01 00:00:00

  • The use of metoprolol and glycopyrrolate to prevent hypotensive/bradycardic events during shoulder arthroscopy in the sitting position under interscalene block.

    abstract:UNLABELLED:Sudden profound hypotensive and/or bradycardic events (HBE) have been reported in >20% of patients undergoing shoulder arthroscopy in the sitting position under interscalene block anesthesia. Retrospective studies suggest that the administration of beta-blockers is safe and may decrease the incidence of thes...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-199812000-00020

    authors: Liguori GA,Kahn RL,Gordon J,Gordon MA,Urban MK

    更新日期:1998-12-01 00:00:00

  • Criteria for selection of ambulatory surgical patients and guidelines for anesthetic management: a retrospective study of 1553 cases.

    abstract::The charts of 1553 patients who were anesthetized for ambulatory surgery were analyzed retrospectively to determine the effect of the type of surgery, the age of the patient, the use of premedication, the duration of anesthesia, and the anesthetic technique on the duration of recovery and the rate of complications. In...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Meridy HW

    更新日期:1982-11-01 00:00:00

  • Continuous small-dose tranexamic acid reduces fibrinolysis but not transfusion requirements during orthotopic liver transplantation.

    abstract::Tranexamic acid (TA) is a synthetic drug that inhibits fibrinolysis. It has been administered to decrease the use of blood products during cardiac surgery and orthotopic liver transplantation when infused in larger doses. A small-dose infusion of aprotinin causes a reduction in fibrinolysis and blood product requireme...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-199708000-00007

    authors: Kaspar M,Ramsay MA,Nguyen AT,Cogswell M,Hurst G,Ramsay KJ

    更新日期:1997-08-01 00:00:00

  • Anesthetic action of opiates: correlations of lipid solubility and spectral edge.

    abstract::The ability of opiates to be a complete anesthetic has been assessed in animals. These studies have investigated the serum levels of opiate required to produce a decrease in anesthetic requirement for a concomitantly administered inhalation anesthetic. A linear dose-response relation has been observed between opiate s...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Stone DJ,DiFazio CA

    更新日期:1988-07-01 00:00:00

  • The impact of saline flush of the epidural catheter on resolution of epidural anesthesia in volunteers: a dose-response study.

    abstract:UNLABELLED:We evaluated the effect of 1, 20, and 40 mL of epidural saline flush on recovery from lidocaine epidural anesthesia. Eight volunteers were studied for three study periods, each separated by 72 h. The volume of saline was randomized, and a new catheter was inserted for each study period. A standardized dose o...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-199910000-00034

    authors: Chan VW,Nazarnia S,Kaszas Z,Perlas A

    更新日期:1999-10-01 00:00:00

  • Adding fentanyl 0.0002% to epidural bupivacaine 0.125% does not delay gastric emptying in laboring parturients.

    abstract::Previous studies have shown that bolus doses of fentanyl (50 and 100 micrograms) with epidural bupivacaine delay gastric emptying by up to 45 min. We studied the effect of the addition of small-dose fentanyl to epidural bupivacaine infusions on gastric emptying during labor. The acetaminophen absorption technique was ...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-199603000-00032

    authors: Zimmermann DL,Breen TW,Fick G

    更新日期:1996-03-01 00:00:00

  • A cryogenic machine for selective recovery of xenon from breathing system waste gases.

    abstract:BACKGROUND:Xenon has many characteristics that make it very attractive as an anesthetic and therapeutic drug. Unfortunately, the supply of xenon is fixed, and therefore reclamation and recovery from even the most efficient breathing circuits is desirable. We built and evaluated a cryogenic device to recover xenon from ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000278148.56305.72

    authors: Dingley J,Mason RS

    更新日期:2007-11-01 00:00:00

  • The effects of ketamine on the temporal summation (wind-up) of the R(III) nociceptive flexion reflex and pain in humans.

    abstract:UNLABELLED:Animal studies have suggested that the temporal summation of nociceptive inputs might play a significant role in the development of central sensitization (i.e., hyperexcitability of central nociceptive neurons) and hyperalgesia via the activation of N-methyl-D-aspartate receptors. To further analyze these pr...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200002000-00031

    authors: Guirimand F,Dupont X,Brasseur L,Chauvin M,Bouhassira D

    更新日期:2000-02-01 00:00:00

  • The impact of postoperative discontinuation or continuation of chronic statin therapy on cardiac outcome after major vascular surgery.

    abstract:BACKGROUND:Statins reduce cardiac morbidity in nonsurgical populations, and may benefit surgical patients. We sought to examine cardiac outcome in patients who continued, compared with those who discontinued, statin therapy after major vascular surgery. METHODS:Prospectively collected data were examined for an associa...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000263029.72643.10

    authors: Le Manach Y,Godet G,Coriat P,Martinon C,Bertrand M,Fléron MH,Riou B

    更新日期:2007-06-01 00:00:00

  • Association of preoperative risk factors with postoperative acute renal failure.

    abstract::We performed a systematic review of 28 studies that examined preoperative risk factors for postoperative renal failure. Included in the studies were 10,865 patients who underwent either vascular, cardiac, general, or biliary surgery. No two studies used the same criteria for acute renal failure. Variability in definit...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:10.1213/00000539-199401000-00023

    authors: Novis BK,Roizen MF,Aronson S,Thisted RA

    更新日期:1994-01-01 00:00:00

  • Desflurane affords greater protection than halothane in the function of mitochondria against forebrain ischemia reperfusion injury in rats.

    abstract:BACKGROUND:Halothane and desflurane have been shown to attenuate neuronal injury; however, the effects of these anesthetics on mitochondria are unclear. We investigated whether halothane and desflurane affect the function of mitochondria after cerebral ischemia in rats. METHODS:Forty male Wistar rats were randomly div...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e318164f2a5

    authors: Zhang B,Wei X,Cui X,Zhou H,Ding W,Li W

    更新日期:2008-04-01 00:00:00

  • Capturing Essential Information to Achieve Safe Interoperability.

    abstract::In this article, we describe the role of "clinical scenario" information to assure the safety of interoperable systems, as well as the system's ability to deliver the requisite clinical functionality to improve clinical care. Described are methods and rationale for capturing the clinical needs, workflow, hazards, and ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000001351

    authors: Weininger S,Jaffe MB,Rausch T,Goldman JM

    更新日期:2017-01-01 00:00:00

  • Xenon Anesthesia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    abstract:BACKGROUND:Xenon anesthesia has been studied for decades. However, no meta-analysis of randomized controlled trials (RCTs) on xenon anesthesia has been conducted. The aim of this study was to systematically review all available evidence from RCTs comparing xenon and other inhaled and IV anesthetics on anesthetic outcom...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1213/ANE.0000000000000914

    authors: Law LS,Lo EA,Gan TJ

    更新日期:2016-03-01 00:00:00

  • Halothane and children: the first quarter century.

    abstract::For the past 25 years, halothane has been the primary anesthetic agent at Children's Hospital, Columbus, Ohio. To confirm our impression that adverse reactions to halothane are rarely a problem in children, we examined the records of 200,311 cases conducted with halothane from June 1, 1958, through May 31, 1983. Life-...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Warner LO,Beach TP,Garvin JP,Warner EJ

    更新日期:1984-09-01 00:00:00

  • Closed-loop coadministration of propofol and remifentanil guided by bispectral index: a randomized multicenter study.

    abstract:BACKGROUND:We have developed a proportional-integral-derivative controller allowing the closed-loop coadministration of propofol and remifentanil, guided by a Bispectral Index (BIS) monitor, during induction and maintenance of general anesthesia. The controller was compared with manual target-controlled infusion. METH...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1213/ANE.0b013e318205680b

    authors: Liu N,Chazot T,Hamada S,Landais A,Boichut N,Dussaussoy C,Trillat B,Beydon L,Samain E,Sessler DI,Fischler M

    更新日期:2011-03-01 00:00:00

  • Propofol anesthesia for children undergoing magnetic resonance imaging: a comparison with isoflurane, nitrous oxide, and a laryngeal mask airway.

    abstract:BACKGROUND:Both propofol infusions with oxygen delivered through nasal cannula and isoflurane/N2O (nitrous oxide) delivered via a laryngeal mask airway (LMA) are used to provide anesthesia for children undergoing magnetic resonance imaging scans. We compared the incidence of adverse events and perioperative physiologic...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0000000000000504

    authors: Heard C,Harutunians M,Houck J,Joshi P,Johnson K,Lerman J

    更新日期:2015-01-01 00:00:00

  • The effects of sevoflurane and halothane anesthesia on cerebral blood flow velocity in children.

    abstract:UNLABELLED:We compared cerebral blood flow velocity during anesthesia with sevoflurane and halothane in 23 children admitted for elective surgery (age, 0.4-9.7 yr; median age, 1.9 yr; ASA physical status I-II). Inhaled induction was performed in a randomized sequence with sevoflurane or halothane. Under steady-state co...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000539-200104000-00017

    authors: Mönkhoff M,Schwarz U,Gerber A,Fanconi S,Bänziger O

    更新日期:2001-04-01 00:00:00