Does pregnancy protect against intrathecal lidocaine-induced transient neurologic symptoms?

abstract：:We designed a prospective, randomized, double-blind study to evaluate the efficacy of the combination of intrathecal sufentanil with a low dose of local anesthetic in an attempt to prolong analgesia in labor. Fifty-two patients received one of the following intrathecal study solutions: 2.5 mg of bupivacaine; 10 microg...

journal_title：Anesthesia and analgesia

authors： Campbell DC,Camann WR,Datta S

更新日期：1995-08-01 00:00:00

abstract：:Hypotensive effects of the intravenous injection of adenine compounds [adenosine triphosphate (ATP), adenosine] were compared with those of sodium nitroprusside (SNP) in rabbits during light, stable halothane anesthesia. ATP and adenosine were almost equipotent in their effects on blood pressure and heart rate. The hy...

journal_title：Anesthesia and analgesia

authors： Fukunaga AF,Flacke WE,Bloor BC

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Propofol-evoked injection site pain is not observed with fospropofol. We hypothesized that unlike propofol, fospropofol does not activate the irritant receptor, transient receptor potential 1 (TRPA1). METHODS:We tested the hypothesis using electrophysiology and behavioral studies. RESULTS:Our data demonstr...

journal_title：Anesthesia and analgesia

authors： Patwardhan A,Edelmayer R,Annabi E,Price T,Malan P,Dussor G

更新日期：2012-10-01 00:00:00

abstract：:In a prospective, randomized, double-blind study, we investigated whether epinephrine increased the efficacy of levobupivacaine and sufentanil during epidural labor analgesia. Seventy term parturients received an epidural injection of levobupivacaine 0.125% and sufentanil 0.75 microg/mL with or without 1:800,000 epine...

journal_title：Anesthesia and analgesia

authors： Soetens FM,Soetens MA,Vercauteren MP

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Calmodulin (CaM) activation by Ca(2+), its translocation to the nucleus, and stimulation of phosphorylation of cyclic adenosine monophosphate response element-binding protein (CREB) (P-CREB) are necessary for new gene expression and have been linked to long-term potentiation, a process important in memory fo...

journal_title：Anesthesia and analgesia

authors： Zhang J,Sutachan JJ,Montoya-Gacharna J,Xu CF,Xu F,Neubert TA,Recio-Pinto E,Blanck TJ

更新日期：2009-10-01 00:00:00

abstract：:To determine the pharmacokinetics of local anesthetics after lumbar sympathetic blocks, total and free (unbound) plasma concentrations of bupivacaine in venous blood samples were measured in 12 patients using a high-performance liquid chromatography (HPLC) technique. Administration of 30 mL of plain bupivacaine 0.175%...

journal_title：Anesthesia and analgesia

authors： Wulf H,Gleim M,Schele HA

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The blood/gas partition coefficient of a certain volatile anesthetic is of clinical importance because it determines its velocity of uptake into and elimination from the body of a patient and thus its pharmacokinetic behavior. To date, the blood/gas partition coefficients of isoflurane, sevoflurane, and desf...

journal_title：Anesthesia and analgesia

authors： Esper T,Wehner M,Meinecke CD,Rueffert H

更新日期：2015-01-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) is a significant cause of morbidity and mortality in the intensive care unit (ICU) and is characterized by lung epithelial and endothelial cell injury, with increased permeability of the alveolar-capillary membrane, leading to pulmonary edema, severe hypoxia, and difficulty w...

journal_title：Anesthesia and analgesia

authors： Lee LK,Medzikovic L,Eghbali M,Eltzschig HK,Yuan X

更新日期：2020-11-01 00:00:00

abstract：:The Meyer-Overton hypothesis predicts that anesthetic potency correlates inversely with lipophilicity; e.g., MAC times the olive oil/gas partition coefficient equals a constant of approximately 1.82 +/- 0.56 atm (mean +/- sd) for conventional inhaled anesthetics. MAC is the minimum alveolar concentration of anesthetic...

journal_title：Anesthesia and analgesia

authors： Won A,Oh I,Liao M,Sonner JM,Harris RA,Laster MJ,Brosnan R,Trudell JR,Eger EI 2nd

更新日期：2006-05-01 00:00:00

abstract：:Elderly patients have a higher risk of developing adverse drug reactions during anesthesia, especially anesthesia affecting cardiovascular performance. In this prospective randomized study we compared quality of induction, hemodynamics, and recovery in elderly patients scheduled for hip fracture surgery and receiving ...

journal_title：Anesthesia and analgesia

authors： Passot S,Servin F,Pascal J,Charret F,Auboyer C,Molliex S

更新日期：2005-05-01 00:00:00

abstract：:Agreement between estimated fibrinogen concentration via thromboelastography and traditional assays is not established in the parturient. We therefore recruited 56 parturients and performed Clauss and functional fibrinogen level (FLEV) tests. Mean difference of measurements was 36.8 mg/dL (95% CI, 21.8-51.9) with a st...

journal_title：Anesthesia and analgesia

authors： Katz D,Hamburger J,Batt D,Zahn J,Beilin Y

更新日期：2019-09-01 00:00:00

abstract：:Noma (cancrum oris) is a disease of poverty and malnutrition, which predominantly affects children younger than 10 years in developing countries. Although the majority of sufferers die of sepsis at the time of the initial infection, or of subsequent starvation due to severe trismus and an inability to eat, a small min...

journal_title：Anesthesia and analgesia

authors： Coupe MH,Johnson D,Seigne P,Hamlin B

更新日期：2013-07-01 00:00:00

abstract：:Several studies have investigated differential block during spinal anesthesia using transcutaneous electrical stimulation (TES) applied to patient's skin. These TES stimuli are claimed to be a surrogate for surgical stimulation, but TES has never been shown to be a realistic surrogate for a surgical stimulus during re...

journal_title：Anesthesia and analgesia

authors： Zaidi AS,Russell IF

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Percutaneous cannulation of the femoral vein, in the pediatric age group, can be technically challenging, especially when performed by residents in training. We examined whether the use of real-time ultrasound guidance is superior to a landmark technique for femoral vein catheterization in children undergoin...

journal_title：Anesthesia and analgesia

authors： Aouad MT,Kanazi GE,Abdallah FW,Moukaddem FH,Turbay MJ,Obeid MY,Siddik-Sayyid SM

更新日期：2010-09-01 00:00:00

abstract：:This research determined the safety and efficacy of two small-dose infusions of dexmedetomidine by evaluating sedation, analgesia, cognition, and cardiorespiratory function. Seven healthy young volunteers provided informed consent and participated on three occasions with random assignment to drug or placebo. Heart rat...

journal_title：Anesthesia and analgesia

authors： Hall JE,Uhrich TD,Barney JA,Arain SR,Ebert TJ

更新日期：2000-03-01 00:00:00

abstract：:The effect of ketamine on intraocular pressure (IOP) was studied in 10 children. Control IOP values were determined prior to induction of anesthesia, following premedication with atropine alone or in combination with pentobarbital and meperidine. After the IM injection of 8 mg/kg of ketamine, the IOP was determined at...

journal_title：Anesthesia and analgesia

authors： Ausinsch B,Rayburn RL,Munson ES,Levy NS

更新日期：1976-11-01 00:00:00

abstract：UNLABELLED:Neuronal baseline K(+) channels were activated by several volatile anesthetics. Whole-cell recordings from cultured cerebellar granule neurons of 7-day-old male Sprague-Dawley rats showed outward-rectifying K(+) currents with a conductance of approximately 1.1 +/- 0.3 nS (n = 20) at positive potentials. The ...

journal_title：Anesthesia and analgesia

authors： Shin WJ,Winegar BD

更新日期：2003-05-01 00:00:00

abstract：:The pandemic of heart failure and the limited options for treatment of end-stage disease have resulted in an increase in the utilization of left ventricular assist devices (LVADs). Improvements in device technology and patient survival have led to an expanding population of patients requiring noncardiac surgery while ...

journal_title：Anesthesia and analgesia

authors： Chung M

更新日期：2018-06-01 00:00:00

abstract：:It is not uncommon to observe prolonged CNS depression for several hours following controlled hypotension and halothane anesthesia for neurosurgery. The present study evaluates possible contribution of large doses of trimethaphan to CNS depression. Four adult sheep were placed on transapical left ventricular bypass (T...

journal_title：Anesthesia and analgesia

authors： Wong KC,Peters JL,Roberts TS,McRea JC,Fukumasu H

更新日期：1977-01-01 00:00:00

abstract：UNLABELLED:We present the case of a 57-yr-old patient who suffered an unexplained cerebrovascular event 3 days after being struck by a motor vehicle. Workup demonstrated a previously unknown patient foramen ovale. The etiologies of paradoxical embolism in trauma are discussed. IMPLICATIONS:Paradoxical embolism after m...

journal_title：Anesthesia and analgesia

authors： Price MD,Kanake P,Talmor D

更新日期：2004-04-01 00:00:00

abstract：:This study was undertaken to compare desflurane with propofol anesthesia in outpatients undergoing peripheral orthopedic surgery. Data were combined from two institutions participating in a multicenter study. Ninety-one patients, ASA physical status I or II, were each randomly assigned to one of four groups. After adm...

journal_title：Anesthesia and analgesia

authors： Rapp SE,Conahan TJ,Pavlin DJ,Levy WJ,Hautman B,Lecky J,Luke J,Nessly ML

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Regional anesthesia is increasingly used in pediatric patients to provide postoperative analgesia and to supplement intraoperative anesthesia. The Pediatric Regional Anesthesia Network was formed to obtain highly audited data on practice patterns and complications and to facilitate collaborative research in ...

journal_title：Anesthesia and analgesia

authors： Polaner DM,Taenzer AH,Walker BJ,Bosenberg A,Krane EJ,Suresh S,Wolf C,Martin LD

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Lung-protective ventilation (LPV) has been demonstrated to improve clinical outcomes in surgical patients. There are very limited data on the current use of LPV for patients undergoing 1-lung ventilation (1LV) despite evidence that 1LV may be a particularly important setting for its use. In this multicenter ...

journal_title：Anesthesia and analgesia

authors： Colquhoun DA,Naik BI,Durieux ME,Shanks AM,Kheterpal S,Bender SP,Blank RS,MPOG Investigators.

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Rapid establishment of a patent airway in ill or injured patients is a priority for prehospital rescue personnel. Out-of-hospital tracheal intubation can be challenging. Unrecognized esophageal intubation is a clinical disaster. METHODS:We performed an observational, prospective study of consecutive patient...

journal_title：Anesthesia and analgesia

authors： Timmermann A,Russo SG,Eich C,Roessler M,Braun U,Rosenblatt WH,Quintel M

更新日期：2007-03-01 00:00:00

abstract：UNLABELLED:In the present study, we examined whether preincisional treatment with dextromethorphan (DM) provides preemptive analgesia. Ninety patients scheduled for laparoscopic cholecystectomy were included. Patients receiving chlorpheniramine maleate (CPM) 20 mg via an IM injection 30 min before skin incision were de...

journal_title：Anesthesia and analgesia

authors： Wu CT,Yu JC,Yeh CC,Liu ST,Li CY,Ho ST,Wong CS

更新日期：1999-06-01 00:00:00

abstract：UNLABELLED:Symptoms of orthostatic intolerance are common after general anesthesia and are associated with an increased risk of postoperative morbidity. The contribution of orthostatic hypotension (OH) has not been well defined. We conducted a head-up tilt test on patients after general anesthesia for minor surgery to ...

journal_title：Anesthesia and analgesia

authors： Cowie DA,Shoemaker JK,Gelb AW

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to identify patient and procedural characteristics associated with postoperative respiratory depression or sedation requiring naloxone intervention. METHODS:We identified patients who received naloxone to reverse opioid-induced respiratory depression or sedation within 48 hours aft...

journal_title：Anesthesia and analgesia

authors： Weingarten TN,Herasevich V,McGlinch MC,Beatty NC,Christensen ED,Hannifan SK,Koenig AE,Klanke J,Zhu X,Gali B,Schroeder DR,Sprung J

更新日期：2015-08-01 00:00:00

abstract：:Both clonidine, an alpha(2) agonist, and morphine, an opioid agonist, provide enhanced patient analgesia after arthroscopic knee surgery when administered via the intraarticular (IA) route. Clonidine potentiates morphine analgesia in the animal model. We designed this study to determine whether clonidine or morphine r...

journal_title：Anesthesia and analgesia

authors： Joshi W,Reuben SS,Kilaru PR,Sklar J,Maciolek H

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine, an α(2)-receptor agonist, prolongs analgesia when used in neuraxial and IV blocks. We evaluated the effect of dexmedetomidine added to ropivacaine for tibial nerve block on the duration of the sensory blockade. METHODS:For this prospective, randomized, controlled, double-blind, crossover tr...

journal_title：Anesthesia and analgesia

authors： Rancourt MP,Albert NT,Côté M,Létourneau DR,Bernard PM

更新日期：2012-10-01 00:00:00

abstract：:Animal studies suggest that increased circulating estrogen and progesterone, and activation of the endorphin system cause prenancy-induced antinociceptive effects. Human studies have provided inconsistent results and have often lacked a nonpregnant control group. In this study, we compared sensitivity to experimental ...

journal_title：Anesthesia and analgesia

authors： Carvalho B,Angst MS,Fuller AJ,Lin E,Mathusamy AD,Riley ET

更新日期：2006-11-01 00:00:00