2,6 di-tert-butylphenol, a nonanesthetic propofol analog, modulates alpha1beta glycine receptor function in a manner distinct from propofol.

abstract：:Ondansetron is a potent antiemetic drug that acts through inhibition of the 5HT3 receptors for serotonin. Minimum alveolar concentration (MAC) for isoflurane is not affected by systemic ondansetron; however ondansetron is a substrate of P-glycoprotein, a transport pump expressed in the blood-brain barrier. Thus, we hy...

journal_title：Anesthesia and analgesia

authors： Scott JA,Wood M,Flood P

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Regional anesthesia is increasingly used in pediatric patients to provide postoperative analgesia and to supplement intraoperative anesthesia. The Pediatric Regional Anesthesia Network was formed to obtain highly audited data on practice patterns and complications and to facilitate collaborative research in ...

journal_title：Anesthesia and analgesia

authors： Polaner DM,Taenzer AH,Walker BJ,Bosenberg A,Krane EJ,Suresh S,Wolf C,Martin LD

更新日期：2012-12-01 00:00:00

abstract：UNLABELLED:alpha(2) Adrenoceptor activity is involved in the mechanism of anesthesia. Clonidine, a alpha(2) adrenoceptor agonist, and yohimbine, a alpha(2) adrenoceptor antagonist, increase and decrease barbiturate-induced sleep times. In this study, we examined the effects of these drugs on propofol-induced sleep time...

journal_title：Anesthesia and analgesia

authors： Kushikata T,Hirota K,Yoshida H,Kubota T,Ishihara H,Matsuki A

更新日期：2002-05-01 00:00:00

abstract：:To further investigate possible prolongation of the frequency-corrected QT interval (QTc interval) after administration of droperidol (DRO), we studied 40 surgical patients who were randomly assigned to one of three groups, receiving an intravenous (IV) injection of either 0.1 mg/kg (Group 1, n = 10), 0.175 mg/kg (Gro...

journal_title：Anesthesia and analgesia

authors： Lischke V,Behne M,Doelken P,Schledt U,Probst S,Vettermann J

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:A potential physicochemical interaction between epidural local anesthetics and extended-release epidural morphine (EREM) could negate the sustained release. In this study, we sought to determine the pharmacokinetic and drug effects of prior epidural lidocaine administration on EREM. METHODS:Thirty healthy w...

journal_title：Anesthesia and analgesia

authors： Atkinson Ralls L,Drover DR,Clavijo CF,Carvalho B

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Although bone cancer-related pain is one of the most disruptive symptoms in patients with advanced cancer, patients are often refractory to pharmacological treatments; thus, more effective treatments for bone cancer pain are needed. We evaluated the analgesic efficacy of and interaction between intrathecal G...

journal_title：Anesthesia and analgesia

authors： Kim WM,Jeong CW,Lee SH,Kim YO,Cui JH,Yoon MH

更新日期：2011-10-01 00:00:00

abstract：:Stellate ganglion block (SGB) is an established procedure for the diagnosis and treatment of chronic pain. SGB results in an acute sympathetic denervation of a part of the left ventricular (LV) wall innervated by the blocked ganglion, which may impair regional contractility. The resulting imbalance of myocardial contr...

journal_title：Anesthesia and analgesia

authors： Schlack W,Schäfer S,Thämer V

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Operating rooms contribute significantly to the increasing volumes and costs of hospital waste. Little is known, however, about doctors' views of hospital waste recycling despite their potential influence in improving recycling programs. We surveyed the waste recycling views held by anesthesiologists in Aust...

journal_title：Anesthesia and analgesia

authors： McGain F,White S,Mossenson S,Kayak E,Story D

更新日期：2012-05-01 00:00:00

abstract：:Fire in the operating room is a rare but potentially devastating event. In this case report, we describe 2 separate fires of a Westmed heated humidification circuit. We conducted a detailed analysis of potential causes of the fires, including a simulation and series of experiments. Our conclusions were (1) a combinati...

journal_title：Anesthesia and analgesia

authors： Laudanski K,Schwab WK,Bakuzonis CW,Paulus DA

更新日期：2010-12-01 00:00:00

abstract：UNLABELLED:A new CO(2) absorbent, Amsorb (A), which does not contain monovalent bases, is ideal because it does not degrade volatile anesthetics to either Compound A (from sevoflurane) or carbon monoxide (from desflurane, enflurane, or isoflurane). The CO(2) absorption capacity of A, however, has not been investigated ...

journal_title：Anesthesia and analgesia

authors： Higuchi H,Adachi Y,Arimura S,Kanno M,Satoh T

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:While transfusion-related acute lung injury (TRALI) remains the primary cause of transfusion-related fatalities (37%), recent reports estimate the incidence of TRALI at 0.008% per unit of plasma transfused and 0.004% per all products transfused. Because blood banks have moved toward male-predominant plasma, ...

journal_title：Anesthesia and analgesia

authors： Meyer DE,Reynolds JW,Hobbs R,Bai Y,Hartwell B,Pommerening MJ,Fox EE,Wade CE,Holcomb JB,Cotton BA

更新日期：2018-08-01 00:00:00

abstract：UNLABELLED:We performed this study to assess the influence of endotracheal tube (ETT) tip design (Murphy-tip versus Magill-tip) on nasal trauma during nasotracheal intubation with a conventional polyvinyl chloride ETT. Patients were randomly allocated to one of four groups (n = 25 each): Magill-tipped ETT and Murphy-ti...

journal_title：Anesthesia and analgesia

authors： Lee JH,Kim CH,Bahk JH,Park KS

更新日期：2005-10-01 00:00:00

abstract：UNLABELLED:Reduction of the inflammatory reaction with the use of heparin coating has been found during and after cardiopulmonary bypass (CPB). The question remains whether this reduced reaction also decreases the magnitude of CPB-induced pulmonary dysfunction. We therefore evaluated the effects of a heparin-coated cir...

journal_title：Anesthesia and analgesia

authors： de Vroege R,van Oeveren W,van Klarenbosch J,Stooker W,Huybregts MA,Hack CE,van Barneveld L,Eijsman L,Wildevuur CR

更新日期：2004-06-01 00:00:00

abstract：UNLABELLED:Adjuncts to local anesthetics for peripheral plexus blockade may enhance the quality and duration of anesthesia and postoperative analgesia. The analgesic, tramadol, has a unique mechanism of action that suggests efficacy as such an adjunct. It displays a central analgesic and peripheral local anesthetic eff...

journal_title：Anesthesia and analgesia

authors： Robaux S,Blunt C,Viel E,Cuvillon P,Nouguier P,Dautel G,Boileau S,Girard F,Bouaziz H

更新日期：2004-04-01 00:00:00

abstract：:This double-blind, randomized, multicenter study was designed to determine the short-term and long-term efficacy of intravenous regional block with guanethidine in patients with reflex sympathetic dystrophy (RSD)/causalgia. Sixty patients were enrolled to receive four intravenous regional blocks at 4-day intervals wit...

journal_title：Anesthesia and analgesia

authors： Ramamurthy S,Hoffman J

更新日期：1995-10-01 00:00:00

abstract：:Bolus doses of propofol in patients for cardioversion often produce hypotension and apnea. Etomidate provides cardiovascular stability in these patients, but myoclonus may interfere with electrocardiographic interpretation. This study was designed to demonstrate whether propofol, when given as a low-dose infusion, can...

journal_title：Anesthesia and analgesia

authors： Hullander RM,Leivers D,Wingler K

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Landmark and ultrasound-guided transversus abdominis plane blocks have demonstrated an opioid-sparing effect postoperatively after cesarean delivery. The more posterior quadratus lumborum (QL) might provide superior local anesthetic spread to the thoracolumbar fascia and paravertebral space. The aim of our s...

journal_title：Anesthesia and analgesia

authors： Krohg A,Ullensvang K,Rosseland LA,Langesæter E,Sauter AR

更新日期：2018-02-01 00:00:00

abstract：UNLABELLED:Diabetic patients are at increased risk of wound infection after major surgery, but the effect of perioperative glucose control on postoperative wound infection rates after surgery is uncertain. We tested the effect of an insulin infusion on perioperative neutrophil function in diabetic patients scheduled fo...

journal_title：Anesthesia and analgesia

authors： Rassias AJ,Marrin CA,Arruda J,Whalen PK,Beach M,Yeager MP

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:The perioperative assessment of right ventricular (RV) function remains a challenge. Tricuspid annular plane systolic excursion (TAPSE) using M-mode is a widely used measure of RV function. However, accurate alignment of the ultrasound beam with the direction of annular movement can be difficult with transes...

journal_title：Anesthesia and analgesia

authors： Shen T,Picard MH,Hua L,Burns SM,Andrawes MN

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Transversus abdominis plane (TAP) block and local anesthetic wound infiltration provide analgesia after cesarean delivery. Studies comparing the 2 techniques are scarce, with conflicting results. This double-blind, randomized controlled trial aimed to compare bilateral ultrasound-guided TAP block with single...

journal_title：Anesthesia and analgesia

authors： Tawfik MM,Mohamed YM,Elbadrawi RE,Abdelkhalek M,Mogahed MM,Ezz HM

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Both femoral and obturator nerve blocks have been suggested to be useful in relieving pain after total knee arthroplasty (TKA). We sought to compare their efficacy. METHODS:Sixty patients undergoing elective unilateral TKA under spinal anesthesia received in a randomized, double-blind manner a femoral, obtu...

journal_title：Anesthesia and analgesia

authors： Kardash K,Hickey D,Tessler MJ,Payne S,Zukor D,Velly AM

更新日期：2007-09-01 00:00:00

abstract：UNLABELLED:We conducted a double-blinded study in 90 patients undergoing elective arthroscopic knee surgery to determine whether there is a role of inflammation in the analgesic efficacy of intraarticular piroxicam. Standardized general anesthetic techniques were used for all patients. At the end of the operation, afte...

journal_title：Anesthesia and analgesia

authors： Izdes S,Orhun S,Turanli S,Erkilic E,Kanbak O

更新日期：2003-10-01 00:00:00

abstract：:The purpose of this study was to determine the analgesic efficacy, opioid-sparing effect, and tolerability of ketorolac administered as an intravenous (i.v.) bolus followed by a continuous infusion after total hip or knee arthroplasty. After general anesthesia, patients received either placebo or ketorolac 30 mg i.v. ...

journal_title：Anesthesia and analgesia

authors： Etches RC,Warriner CB,Badner N,Buckley DN,Beattie WS,Chan VW,Parsons D,Girard M

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Patients with lung failure who undergo prone positioning often receive extended hemodynamic monitoring. We investigated the influence of modified prone positioning (135°) on the accuracy of pulse contour-derived calibrated cardiac index (CIPC) and uncalibrated cardiac index (CIVIG) in this patient population...

journal_title：Anesthesia and analgesia

authors： Grensemann J,Bruecken U,Treszl A,Wappler F,Sakka SG

更新日期：2013-04-01 00:00:00

abstract：:Controversy exists concerning the choice of anesthetic technic for elective cesarean section. Several maternal and newborn parameters were compared during general anesthesia (GA) and lumbar epidural analgesia (LEA). High inspired maternal O2 levels were achieved with both technics. Vigorous, well-oxygenated infants wi...

journal_title：Anesthesia and analgesia

authors： James FM 3rd,Crawford JS,Hopkinson R,Davies P,Naiem H

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:Lidocaine can alleviate acute as well as chronic neuropathic pain at very low plasma concentrations in humans and laboratory animals. The mechanism(s) underlying lidocaine's analgesic effect when administered systemically is poorly understood but clearly not related to interruption of peripheral nerve conduc...

journal_title：Anesthesia and analgesia

authors： Luo Z,Yu M,Smith SD,Kritzer M,Du C,Ma Y,Volkow ND,Glass PS,Benveniste H

更新日期：2009-01-01 00:00:00

abstract：:Phenylephrine and methoxamine are direct-acting, predominantly α(1) adrenergic receptor (AR) agonists. To better understand their physiologic effects, we screened 463 articles on the basis of PubMed searches of "methoxamine" and "phenylephrine" (limited to human, randomized studies published in English), as well as ci...

journal_title：Anesthesia and analgesia

authors： Thiele RH,Nemergut EC,Lynch C 3rd

更新日期：2011-08-01 00:00:00

abstract：UNLABELLED:The transient hyperemic response (THR) in the middle cerebral artery (MCA) after the release of brief compression of the ipsilateral common carotid artery has been used to study cerebral autoregulation. We conducted the present study to evaluate the reliability of THR to detect changes in cerebral autoregula...

journal_title：Anesthesia and analgesia

authors： Mahajan RP,Cavill G,Simpson EJ

更新日期：1998-10-01 00:00:00

abstract：:Local anesthetics have been used clinically for more than a century, but new insights into their mechanisms of action and their interaction with biological systems continue to surprise researchers and clinicians alike. Next to their classic action on voltage-gated sodium channels, local anesthetics interact with calci...

journal_title：Anesthesia and analgesia

authors： Lirk P,Hollmann MW,Strichartz G

更新日期：2018-04-01 00:00:00

abstract：:Preoperative local anesthetic blockade of somatosensory pathways involved with skin incision and other noxious perioperative stimuli may "preempt" or attenuate the postoperative pain response. Since the Pfannenstiel incision lies within the L1 dermatome, bilateral ilioinguinal, iliohypogastric nerve blocks (IINBs) sho...

journal_title：Anesthesia and analgesia

authors： Huffnagle HJ,Norris MC,Leighton BL,Arkoosh VA

更新日期：1996-01-01 00:00:00