The physiologic implications of isolated alpha(1) adrenergic stimulation.

abstract：:Bradykinin, an endogenous nonapeptide and an important mediator of inflammation, is also implicated in the initiation and maintenance of pain. Both des-Arg(8), Leu(8)-bradykinin (dALBK) and HOE-140, the prototypic bradykinin B1 and B2 receptor antagonists, respectively, have been shown to reduce pain behaviors and inf...

journal_title：Anesthesia and analgesia

authors： Leonard PA,Arunkumar R,Brennan TJ

更新日期：2004-10-01 00:00:00

abstract：:Postoperative nausea and vomiting is common after cardiac surgery and may contribute to significant morbidity. Gastric decompression during anesthesia has been used for postoperative nausea and vomiting prophylaxis in shorter duration noncardiac surgery with conflicting results. We tested the hypothesis that gastric d...

journal_title：Anesthesia and analgesia

authors： Burlacu CL,Healy D,Buggy DJ,Twomey C,Veerasingam D,Tierney A,Moriarty DC

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Tardiness from scheduled start times is a common source of frustration for both operating room (OR) personnel and patients. Factors that influence tardiness were quantified in a companion paper and have been used to develop interventions that have the potential for reducing tardiness. METHODS:Data from two ...

journal_title：Anesthesia and analgesia

authors： Wachtel RE,Dexter F

更新日期：2009-06-01 00:00:00

abstract：:The effects of enflurane and halothane anesthesia on systolic time intervals were studied in 12 healthy patients. Cardiovascular measurements were made at equipotent levels of anesthesia: enflurane 1.23% end-tidal and halothane 0.65% end-tidal. These agents were studied first with 50% N2O and then without N2O. Systoli...

journal_title：Anesthesia and analgesia

authors： Kaplan JA,Miller ED,Bailey DR

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Manikins are widely used in airway management training; however, simulation of realism and interpatient variability remains a challenge. We investigated whether cadavers embalmed with the novel Fix for Life (F4L) embalmment method are a suitable and realistic model for teaching 3 basic airway skills: facemas...

journal_title：Anesthesia and analgesia

authors： van Emden MW,Geurts JJ,Schober P,Schwarte LA

更新日期：2018-10-01 00:00:00

abstract：:We have developed computer software to store data on all surgical and obstetrical anesthetics administered by our department. The computer system provides information for monitoring the residency training program, department and operating room management, professional fee billing, and research. It imposes little addit...

journal_title：Anesthesia and analgesia

authors： Bashein G,Barna CR

更新日期：1985-04-01 00:00:00

abstract：:This article describes practices in patient blood management (PBM) in 4 countries on different continents that may provide insights for anesthesiologists and other physicians working in global settings. The article has its foundation in the proceedings of a session at the 2014 AABB annual meeting during which internat...

journal_title：Anesthesia and analgesia

authors： Eichbaum Q,Murphy M,Liu Y,Kajja I,Hajjar LA,Smit Sibinga CT,Shan H

更新日期：2016-12-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：:Fluid resuscitation is one of the most prevalent treatment in critical care. There is not definitive evidence about the best fluid for resuscitation. The aim of this review will be to asses the efficacy and safety of buffered solution versus saline. We will perform an electronic search in Medline, Embase, and Central....

journal_title：Anesthesia and analgesia

authors： Barea-Mendoza JA,Antequera AM,Plana MN,Chico-Fernández M,Muriel A,Sáez I,Estrada-Lorenzo JM,Montejo-González JC

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Helium produces preconditioning against myocardial infarction by activating prosurvival signaling, but whether nitric oxide (NO) generated by endothelial NO synthase plays a role in this phenomenon is unknown. We tested the hypothesis that NO mediates helium-induced cardioprotection in vivo. METHODS:Rabbits...

journal_title：Anesthesia and analgesia

authors： Pagel PS,Krolikowski JG,Pratt PF Jr,Shim YH,Amour J,Warltier DC,Weihrauch D

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Respiratory complications were associated with half of pediatric malpractice claims from the 1970s to 1980s in the ASA Closed Claims Database. Advances in pediatric anesthesia practice have occurred in the 1980s and 1990s and may be reflected in liability trends. METHODS:We reviewed 532 pediatric (age < or ...

journal_title：Anesthesia and analgesia

authors： Jimenez N,Posner KL,Cheney FW,Caplan RA,Lee LA,Domino KB

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Increasing evidence links postoperative cognitive dysfunction (POCD) to surgery and anesthesia. POCD is recognized as an important neuropsychological adverse outcome in surgical patients, particularly the elderly. This prospective cohort study aimed to investigate whether POCD is associated with impaired int...

journal_title：Anesthesia and analgesia

authors： Goettel N,Burkhart CS,Rossi A,Cabella BC,Berres M,Monsch AU,Czosnyka M,Steiner LA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:During mechanical ventilation of infants and neonates, small changes in tidal volume may lead to hypo- or hyperventilation, barotrauma, or volutrauma. Partly because breathing circuit compliance and fresh gas flow affect tidal volume delivery by traditional anesthesia ventilators in volume-controlled ventila...

journal_title：Anesthesia and analgesia

authors： Bachiller PR,McDonough JM,Feldman JM

更新日期：2008-05-01 00:00:00

abstract：UNLABELLED:Postanesthetic shivering can be treated with many types of drugs. We compared the effects of meperidine, clonidine, and urapidil on postanesthetic shivering. Sixty patients shivering during recovery from general anesthesia were treated in a randomized, double-blinded fashion with 25 mg meperidine IV, 0.15 mg...

journal_title：Anesthesia and analgesia

authors： Schwarzkopf KR,Hoff H,Hartmann M,Fritz HG

更新日期：2001-01-01 00:00:00

abstract：:Hospitals rely on pagers and ordinary telephones to reach staff members in emergency situations. New telecommunication technologies such as General Packet Radio Service (GPRS), the third generation mobile phone system Universal Mobile Telecommunications System (UMTS), and Wireless Local Area Network (WLAN) might be ab...

journal_title：Anesthesia and analgesia

authors： Wallin MK,Marve T,Hakansson PK

更新日期：2005-11-01 00:00:00

abstract：:Renal blood flow (RBF) and arterial blood pressure (BP) were monitored in 12 patients undergoing nephrolithotomy in the lateral flexed position. All patients were preoxygenated and were anesthetized with sodium thiopental, N2O, O2, and fentanyl. Maintenance relaxation was obtained with pancuronium bromide. Arterial pr...

journal_title：Anesthesia and analgesia

authors： Birch AA,Boyce WH

更新日期：1976-09-01 00:00:00

abstract：UNLABELLED:Because inhibition of voltage-dependent Ca(2+) channels can be a mechanism underlying general anesthesia, we examined sensitivities to propofol and halothane in mice lacking the R-type (Ca(v)2.3) channel widely expressed in neurons. Sleep time after propofol injection (26 mg/kg IV) and halothane MAC(RR) and ...

journal_title：Anesthesia and analgesia

authors： Takei T,Saegusa H,Zong S,Murakoshi T,Makita K,Tanabe T

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Nerve-stimulated fade in muscle is generally accepted as a prejunctional phenomenon mediated by block of prejunctional acetylcholine receptors (AChRs) at the nerve terminal, whereas decrease of twitch tension is considered a postjunctional effect due to block of muscle AChRs. Using ligands with specific pre-...

journal_title：Anesthesia and analgesia

authors： Nagashima M,Yasuhara S,Martyn JA

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The effect of neither transfusion guidelines nor decision support tools on intraoperative transfusion has been previously evaluated. The University of Michigan introduced a transfusion guideline in 2009, and in 2011, the Department of Anesthesiology developed a transfusion decision support tool. The primary ...

journal_title：Anesthesia and analgesia

authors： Picton P,Starr J,Kheterpal S,Thompson AML,Housey M,Sathishkumar S,Dubovoy T,Kirkpatrick N,Tremper KK,Engoren M,Ramachandran SK

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Erythropoiesis-stimulating agents, such as erythropoietin (EPO), can be used to treat preoperative anemia. Some studies suggest an increased risk of mortality and thrombotic events, and use in cardiovascular surgery remains off-label. This study compares outcomes in cardiac surgery patients declining blood t...

journal_title：Anesthesia and analgesia

authors： Duce L,Cooter ML,McCartney SL,Lombard FW,Guinn NR

更新日期：2018-08-01 00:00:00

abstract：:To compare the dose-response of remifentanil for tracheal intubation in infants and children, 32 healthy full-term infants and 32 children were anesthetized with 10 mug/kg glycopyrrolate and 4.0 mg/kg propofol and administered 1 of 4 doses of remifentanil (1.25, 1.50, 1.75, or 2.00 microg/kg) to facilitate tracheal in...

journal_title：Anesthesia and analgesia

authors： Crawford MW,Hayes J,Tan JM

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Pathophysiologic changes in children with congenital heart disease may alter the effect of drugs by influencing the pharmacokinetics (PK). Considering the limited literature that describes the PK of etomidate in pediatric patients, especially in those with tetralogy of Fallot (TOF), our aim was to characteri...

journal_title：Anesthesia and analgesia

authors： Shen Y,Cai MH,Ji W,Bai J,Huang Y,Sun Y,Lin L,Niu J,Zhang MZ

更新日期：2016-09-01 00:00:00

abstract：:The development of complex regional pain syndrome (CRPS) is not an uncommon complication after Dupuytren's surgery. Despite increasing research interest, little is known regarding which patients are at increased risk for developing CRPS and what is the optimal perioperative treatment strategy for preventing the occurr...

journal_title：Anesthesia and analgesia

authors： Reuben SS,Pristas R,Dixon D,Faruqi S,Madabhushi L,Wenner S

更新日期：2006-02-01 00:00:00

abstract：UNLABELLED:Morbidly obese (MO) patients undergoing laparoscopy have lower PaO(2) compared with normal-weight (NW) patients. We hypothesized that increases in tidal volume (V(T)) or respiratory rate (RR) would improve oxygenation. All measurements were performed at: 1) baseline: V(T) 600-700 mL and 10 breaths/min, 2) do...

journal_title：Anesthesia and analgesia

authors： Sprung J,Whalley DG,Falcone T,Wilks W,Navratil JE,Bourke DL

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle calcium regulation associated primarily, but not exclusively, with mutations in the skeletal muscle ryanodine receptor. Associated environmental factors, however, may also be important for expression of the syndrome. METHODS AND RE...

journal_title：Anesthesia and analgesia

authors： Capacchione JF,Radimer MC,Sagel JS,Kraus GP,Sambuughin N,Muldoon SM

更新日期：2009-03-01 00:00:00

abstract：UNLABELLED:Intraoperative transesophageal echocardiography (TEE) is frequently used in children with congenital heart disease (CHD). Although transnasal TEE is being used in various settings in the adult population, there are no descriptions of its use intraoperatively in patients with CHD. This report describes the su...

journal_title：Anesthesia and analgesia

authors： Aronson LA

更新日期：2003-12-01 00:00:00

abstract：:Previous studies have shown that bolus doses of fentanyl (50 and 100 micrograms) with epidural bupivacaine delay gastric emptying by up to 45 min. We studied the effect of the addition of small-dose fentanyl to epidural bupivacaine infusions on gastric emptying during labor. The acetaminophen absorption technique was ...

journal_title：Anesthesia and analgesia

authors： Zimmermann DL,Breen TW,Fick G

更新日期：1996-03-01 00:00:00

abstract：:The effects of halothane and enflurane anesthesia under conditions of normo-, hyper-, and hypocarbia on the autoregulation of cerebral blood flow (CBF) in the goat were evaluated. The goat was selected because of its unique arterial blood supply to the head and the development of a method by which CBF may be continuou...

journal_title：Anesthesia and analgesia

authors： Miletich DJ,Ivankovich AD,Albrecht RF,Reimann CR,Rosenberg R,McKissic ED

更新日期：1976-01-01 00:00:00

abstract：UNLABELLED:In this study, we compared the direct myocardial depressant effects of sevoflurane, isoflurane, and halothane and determined whether an L-type Ca2+ channel agonist, Bay K 8644, could attenuate the myocardial depression induced by these anesthetics in cultured neonatal rat ventricular myocytes. Ventricular my...

journal_title：Anesthesia and analgesia

authors： Kanaya N,Kawana S,Tsuchida H,Miyamoto A,Ohshika H,Namiki A

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Chemical pleurodesis causes severe pain, prompting physicians to perform thoracoscopic talc poudrage under general or neuroleptanalgesia. We describe a novel method for pain control in five patients with pneumothoraces and severe chronic obstructive pulmonary disease. METHODS:Patients were premedicated with...

journal_title：Anesthesia and analgesia

authors： Lee P,Colt HG

更新日期：2007-01-01 00:00:00