Bradykinin antagonists have no analgesic effect on incisional pain.

abstract：:Common practice during local anesthetic injection is to warn the patient using words such as: "You will feel a big bee sting; this is the worst part." Our hypothesis was that using gentler words for administration of the local anesthetic improves pain perception and patient comfort. One hundred forty healthy women at ...

journal_title：Anesthesia and analgesia

authors： Varelmann D,Pancaro C,Cappiello EC,Camann WR

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The incremental dose of opioids used in chronic pain management often leads to a reduced opioid analgesic effect, opioid misuse, and addiction. Central dopamine (DA) dysfunction contributes to the chronicity of pain and a decreased opioid analgesic effect. Methylphenidate (MPH/Ritalin) enhances central DA fu...

journal_title：Anesthesia and analgesia

authors： You Z,Ding W,Doheny JT,Shen S,Yang J,Yang L,Chen L,Zhu S,Mao J

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The perioperative course of patients undergoing intracranial surgery is frequently complicated by hypertensive episodes. Dexmedetomidine (DEX), an alpha-2 adrenoreceptor agonist, is gaining popularity in neuroanesthesia, because its sympatholytic and antinociceptive properties may improve hemodynamic stabili...

journal_title：Anesthesia and analgesia

authors： Bekker A,Sturaitis M,Bloom M,Moric M,Golfinos J,Parker E,Babu R,Pitti A

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Intraoperative hypoglycemia can result in devastating neurologic injury if not promptly diagnosed and treated. Few studies have defined risk factors for intraoperative hypoglycemia. The authors sought to characterize children with intraoperative hypoglycemia and determine independent risk factors in a multic...

journal_title：Anesthesia and analgesia

authors： Riegger LQ,Leis AM,Golmirzaie KH,Malviya S

更新日期：2020-06-25 00:00:00

abstract：BACKGROUND:Multiple interventions have been tested in models of cardiopulmonary resuscitation (CPR) to optimize drug use, chest compressions, and ventilation. None has studied the effects of positive end-expiratory pressure (PEEP) on outcome. We hypothesized that because PEEP can reverse pulmonary atelectasis, lower pu...

journal_title：Anesthesia and analgesia

authors： McCaul C,Kornecki A,Engelberts D,McNamara P,Kavanagh BP

更新日期：2009-10-01 00:00:00

abstract：:A 7-year-old girl manifested the rare anomaly of a ventricular septal defect (VSD) with left aortic arch, right descending aorta, and right ligamentum arteriosum. After open-heart surgery to correct the VSD, symptoms of tracheal obstruction on spontaneous breathing developed, due to tracheal compression by the right l...

journal_title：Anesthesia and analgesia

authors： Moorthy SS,Franken EA,LoSasso AM,King H

更新日期：1976-07-01 00:00:00

abstract：:The hemodynamic effects of an induction dose of propofol, 2.5 mg/kg, or etomidate, 0.3 mg/kg, were studied in eight dogs. In addition, cardiodynamic changes were measured using a left ventricular catheter and needle force probes. Propofol was associated with significant decreases in systolic (19.9%) and diastolic (25....

journal_title：Anesthesia and analgesia

authors： Brüssel T,Theissen JL,Vigfusson G,Lunkenheimer PP,Van Aken H,Lawin P

更新日期：1989-07-01 00:00:00

abstract：:Ketanserin, a serotonin antagonist, was used to control blood pressure during cardiopulmonary bypass in 12 patients having cardiac surgery. The drug was administered as a 10 mg bolus followed by a continuous infusion of either 40, 80, or 120 mg/hr to maintain mean arterial blood pressure below 70 mm Hg. There were 16 ...

journal_title：Anesthesia and analgesia

authors： Lichtenthal PR,Wade LD,Rossi EC

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:The accurate measurement of oxygen consumption (VO2) and energy expenditure (EE) may be helpful to optimize the treatment of critically ill patients. However, current techniques are limited in their ability to accurately quantify these end points in infants due to a low VO2, low tidal volume, and rapid respi...

journal_title：Anesthesia and analgesia

authors： Nachman E,Clemensen P,Santos K,Cole AR,Polizzotti BD,Hofmann G,Leeman KT,van den Bosch SJ,Kheir JN

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Current guidelines from the American College of Obstetricians and Gynecologists recommend antibiotic prophylaxis for cesarean delivery immediately before incision. The purpose of this study was to measure and describe correlates of adherence to these guidelines in a sample of United States anesthesiologists....

journal_title：Anesthesia and analgesia

authors： Raghunathan K,Connelly NR,Friderici J,Naglieri-Prescod D,Joyce R,Prasanna P,Ponnusamy N

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Increasing evidence links postoperative cognitive dysfunction (POCD) to surgery and anesthesia. POCD is recognized as an important neuropsychological adverse outcome in surgical patients, particularly the elderly. This prospective cohort study aimed to investigate whether POCD is associated with impaired int...

journal_title：Anesthesia and analgesia

authors： Goettel N,Burkhart CS,Rossi A,Cabella BC,Berres M,Monsch AU,Czosnyka M,Steiner LA

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Whether intraoperative analgesics have an impact on postoperative cancer recurrence is unknown. Some investigations suggest that the opioids could favor relapse and that regional analgesia and nonsteroidal antiinflammatory drugs could improve cancer prognosis. We retrospectively reviewed our series of breast...

journal_title：Anesthesia and analgesia

authors： Forget P,Vandenhende J,Berliere M,Machiels JP,Nussbaum B,Legrand C,De Kock M

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Landmark and ultrasound-guided transversus abdominis plane blocks have demonstrated an opioid-sparing effect postoperatively after cesarean delivery. The more posterior quadratus lumborum (QL) might provide superior local anesthetic spread to the thoracolumbar fascia and paravertebral space. The aim of our s...

journal_title：Anesthesia and analgesia

authors： Krohg A,Ullensvang K,Rosseland LA,Langesæter E,Sauter AR

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:A new benzodiazepine, remimazolam, which is rapidly metabolized by tissue esterases to an inactive metabolite, has been developed to permit a fast onset, a short, predictable duration of sedative action, and a more rapid recovery profile than currently available drugs. We report on modeling of the data and s...

journal_title：Anesthesia and analgesia

authors： Wiltshire HR,Kilpatrick GJ,Tilbrook GS,Borkett KM

更新日期：2012-08-01 00:00:00

abstract：:Jet ventilation is often used during laryngoscopy to permit improved visualization of the larynx and to eliminate a potentially flammable endotracheal tube when laser surgery of the airway is performed. Observation of chest wall movement and blood gas analysis are the usual standards for assessing the adequacy of vent...

journal_title：Anesthesia and analgesia

authors： Gottschalk A,Mirza N,Weinstein GS,Edwards MW

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Although bone cancer-related pain is one of the most disruptive symptoms in patients with advanced cancer, patients are often refractory to pharmacological treatments; thus, more effective treatments for bone cancer pain are needed. We evaluated the analgesic efficacy of and interaction between intrathecal G...

journal_title：Anesthesia and analgesia

authors： Kim WM,Jeong CW,Lee SH,Kim YO,Cui JH,Yoon MH

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Risk of intraoperative hypothermia is relatively high in middle-aged and elderly patients undergoing curative resection of esophageal cancer, which may cause myocardial ischemia during the early postoperative period. The objective of this study was to compare aggressive or standard body temperature managemen...

journal_title：Anesthesia and analgesia

authors： Zhang Z,Xu M,Wu D,Zhang X,Wu J

更新日期：2019-08-01 00:00:00

abstract：:Dantrolene effectively treats malignant hyperthermia (MH) hut the current form, Dantrium, must be dissolved to a 0.33 mg/mL, pH 9.5 solution. This study describes lecithin-coated microcrystal formulations of sodium dantrolene (MC-NaD) and neutral dantrolene (MC-D) which reconstitute to 200 mg/mL within 1 min. In rats,...

journal_title：Anesthesia and analgesia

authors： Karan SM,Lojeski EW,Haynes DH,Bina S,Wesche DL,Boedeker BH,Muldoon SM

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The goal of this study was to determine a set of timing, shape, and statistical features available through noninvasive monitoring of maternal electrocardiogram and photoplethysmography that identifies preeclamptic patients. METHODS:Pregnant women admitted to Labor and Delivery were monitored with pulse oxim...

journal_title：Anesthesia and analgesia

authors： Euliano TY,Michalopoulos K,Singh S,Gregg AR,Del Rio M,Vasilopoulos T,Johnson AM,Onkala A,Darmanjian S,Euliano NR,Ho M

更新日期：2018-03-01 00:00:00

abstract：UNLABELLED:We examined the effects of two perioperative pain management techniques on recovery after laparotomy, as assessed by body weight (BW) and food consumption (FC). All rats received a preoperative intrathecal mixture of morphine plus bupivacaine combined with one of two treatments: (a) injection of slow-release...

journal_title：Anesthesia and analgesia

authors： Shavit Y,Fish G,Wolf G,Mayburd E,Meerson Y,Yirmiya R,Beilin B

更新日期：2005-10-01 00:00:00

abstract：:The onset and intensity of blockade of the lumbosacral dermatomes after epidural anesthesia with alkalinized lidocaine were investigated in a randomized, double-blind study in 26 patients. Control subjects (n = 13) received 20 mL of 1.37% lidocaine (1.5% lidocaine plus 1 mL saline per 10 mL lidocaine) with added 1:200...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Toleikis JR,Dixit P,Goodman I,Hill JA

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:In patients with mitral regurgitation (MR), the effective regurgitant orifice area can be estimated by measuring the vena contracta area (VCA). We hypothesize that the VCA has characteristic temporal dynamics related to the underlying mechanism of functional mitral regurgitation (FMR) versus degenerative mit...

journal_title：Anesthesia and analgesia

authors： Cobey FC,Ashihkmina E,Edrich T,Fox J,Shook D,Bollen B,Breeze JL,Ursprung WW,Shernan SK

更新日期：2016-02-01 00:00:00

abstract：:The aim of this study was to determine the significance of new electrocardiographic (ECG) ST elevation during coronary artery bypass surgery. Multilead ECGs were recorded intraoperatively approximately every 3 min on 105 patients. Cases of new ST elevation were divided into ischemic and those considered to be due to n...

journal_title：Anesthesia and analgesia

authors： Jain U,Wallis DE,Moran JF

更新日期：1994-04-01 00:00:00

abstract：:Reactive oxygen species (ROS) are central to cardiac ischemic and reperfusion injury. They contribute to myocardial stunning, infarction and apoptosis, and possibly to the genesis of arrhythmias. Multiple laboratory studies and clinical trials have evaluated the use of scavengers of ROS to protect the heart from the e...

journal_title：Anesthesia and analgesia

authors： Kevin LG,Novalija E,Stowe DF

更新日期：2005-11-01 00:00:00

abstract：UNLABELLED:The calcium channel blocker nifedipine has analgesic properties that are enhanced by nicotine. Although it is not known how this analgesic state might affect the awareness of anginal pain and impending myocardial infraction, recent studies have shown an increased mortality associated with the use of large do...

journal_title：Anesthesia and analgesia

authors： Hunt TE,Wu WH,Zbuzek VK

更新日期：1998-11-01 00:00:00

abstract：:In recent years the off-label use of recombinant activated factor VII (rFVIIa) has markedly increased, particularly in pediatric cardiac surgery patients, and practitioners differ widely in their usage of the drug. In 2009, the Congenital Cardiac Anesthesia Society (CCAS) assembled a task force to review the literatur...

journal_title：Anesthesia and analgesia

authors： Guzzetta NA,Russell IA,Williams GD

更新日期：2012-08-01 00:00:00

abstract：:Patients receiving metoprolol before cardiac revascularization surgery were randomly divided into those in whom metoprolol was discontinued before the operation (N = 10) and those in whom metoprolol was continued up to the time of operation (N = 10). Cardiovascular responses to neuroleptanesthesia and sternotomy were ...

journal_title：Anesthesia and analgesia

authors： Pontén J,Häggendal J,Milocco I,Waldenström A

更新日期：1983-04-01 00:00:00

abstract：UNLABELLED:We tested the hypothesis that routine cleaning and autoclaving does not remove protein deposits from reusable laryngeal mask airways (LMAs). All previously used classic and flexible LMAs from a single hospital were tested. Each LMA was hand-washed in an enzymatic solution for 3 min, machine-washed with a dis...

journal_title：Anesthesia and analgesia

authors： Clery G,Brimacombe J,Stone T,Keller C,Curtis S

更新日期：2003-10-01 00:00:00

abstract：IMPLICATIONS:Complications of IV mannitol administration resulting in compartment syndrome may warrant surgical intervention. Compartment syndrome is difficult to diagnose in the anesthetized patient. Infusing mannitol in an observed IV site permits discontinuation of mannitol before complications ensue. Early recognit...

journal_title：Anesthesia and analgesia

authors： Edwards JJ,Samuels D,Fu ES

更新日期：2003-01-01 00:00:00

abstract：UNLABELLED:Cryoanalgesia versus sham treatment was applied to the ilioinguinal and iliohypogastric nerves after mesh repair of an inguinal hernia under local anesthesia in 48 male patients in a prospective, randomized, and observer- and patient-blinded trial. Pain was scored daily during rest, while coughing, and durin...

journal_title：Anesthesia and analgesia

authors： Callesen T,Bech K,Thorup J,Andersen J,Nielsen R,Roikjaer O,Kehlet H

更新日期：1998-10-01 00:00:00