Effects of alfentanil on isolated cardiac tissues of the rabbit.

abstract：BACKGROUND:The US Food and Drug Administration (FDA) conducts inspections of clinical investigation sites as a component of clinical trial regulation. The FDA describes the results of these inspections in the Clinical Investigator Inspection List (CLIIL). More serious violations are followed up in FDA warning letters i...

journal_title：Anesthesia and analgesia

authors： Romano CA,Nair S,Delphin ES

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine, an α(2)-receptor agonist, prolongs analgesia when used in neuraxial and IV blocks. We evaluated the effect of dexmedetomidine added to ropivacaine for tibial nerve block on the duration of the sensory blockade. METHODS:For this prospective, randomized, controlled, double-blind, crossover tr...

journal_title：Anesthesia and analgesia

authors： Rancourt MP,Albert NT,Côté M,Létourneau DR,Bernard PM

更新日期：2012-10-01 00:00:00

abstract：:The evolution of modern anesthesia and surgical practices has been accompanied by enhanced supportive procedures in blood banking and transfusion medicine. There is increased focus on the preparation and the use of blood components including, but not limited to, preventing unnecessary type and screen/crossmatch orders...

journal_title：Anesthesia and analgesia

authors： White MJ,Hazard SW 3rd,Frank SM,Boyd JS,Wick EC,Ness PM,Tobian AA

更新日期：2015-06-01 00:00:00

abstract：:Albino rats were chronically exposed for 40 hours a week to 10 ppm halothane in air during early development (conception to day 60), adult life (day 60 to day 135), or both. An unexposed group served as a control. Rats exposed during early development made 30 percent more errors than rats unexposed during this period ...

journal_title：Anesthesia and analgesia

authors： Quimby KL,Katz J,Bowman RE

更新日期：1975-09-01 00:00:00

abstract：:Anecdotal reports suggest that soda lime and Baralyme brand absorbent can degrade inhaled anesthetics to carbon monoxide (CO). We examined the factors that govern CO production and found that these include: 1) The anesthetic used: for a given minimum alveolar anesthetic concentration (MAC)-multiple, the magnitude of C...

journal_title：Anesthesia and analgesia

authors： Fang ZX,Eger EI 2nd,Laster MJ,Chortkoff BS,Kandel L,Ionescu P

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Blood product transfusion is the most commonly performed hospital procedure. Intraoperative blood product utilization varies between institutions and anesthesiologists. In the United States in 2011, nearly 4 million plasma units were transfused. METHODS:A retrospective analysis of intraoperative plasma orde...

journal_title：Anesthesia and analgesia

authors： Meyer MJ,Dzik WH,Levine WC

更新日期：2017-02-01 00:00:00

abstract：IMPLICATIONS:Esophageal insufflation can occur simultaneously with venting from the drain tube during positive pressure ventilation with the ProSeal laryngeal mask airway. ...

journal_title：Anesthesia and analgesia

authors： Stix MS,Borromeo CJ,O'Connor CJ Jr

更新日期：2002-04-01 00:00:00

abstract：:The electroencephalograms of seven elderly (70-85 years) and seven younger patients (23-31 years) anesthetized with a concentration of isoflurane sufficient to produce burst suppression were studied. Anesthesia in these unpremedicated subjects was induced by inhalation of nitrous oxide, isoflurane, and oxygen. Trachea...

journal_title：Anesthesia and analgesia

authors： Schwartz AE,Tuttle RH,Poppers PJ

更新日期：1989-01-01 00:00:00

abstract：UNLABELLED:We compared three ventilators-Servo 900C (Siemens Medical Systems, Danvers, MA), Aestiva 3000 (Datex-Ohmeda, Madison, WI), and NAD 6000 (North American Dräger, Telford, PA)-set to deliver pressure control ventilation using an infant test lung model. Ventilator settings were selected to test "near-maximum" se...

journal_title：Anesthesia and analgesia

authors： Stayer SA,Bent ST,Skjonsby BS,Frolov A,Andropoulos DB

更新日期：2000-11-01 00:00:00

abstract：:The purpose of this study was to determine the analgesic efficacy, opioid-sparing effect, and tolerability of ketorolac administered as an intravenous (i.v.) bolus followed by a continuous infusion after total hip or knee arthroplasty. After general anesthesia, patients received either placebo or ketorolac 30 mg i.v. ...

journal_title：Anesthesia and analgesia

authors： Etches RC,Warriner CB,Badner N,Buckley DN,Beattie WS,Chan VW,Parsons D,Girard M

更新日期：1995-12-01 00:00:00

abstract：IMPLICATIONS:Tizanidine was given systemically to rats with experimental postoperative pain. Partial pain relief was obtained, but the effect was not clinically significant. Although systemic tizanidine is effective in relieving experimental neuropathic pain, it is not as effective for postoperative pain. ...

journal_title：Anesthesia and analgesia

authors： Hord AH,Denson DD,Azevedo MI

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:There is a considerable discrepancy between the reported incidences of awareness under anesthesia in children (0.2%-2.7%). In this prospective, observational, cohort study we evaluated 1) the incidence of awareness during general anesthesia in children across three settings, 2) factors contributing to awaren...

journal_title：Anesthesia and analgesia

authors： Malviya S,Galinkin JL,Bannister CF,Burke C,Zuk J,Popenhagen M,Brown S,Voepel-Lewis T

更新日期：2009-11-01 00:00:00

abstract：UNLABELLED:Sudden profound hypotensive and/or bradycardic events (HBE) have been reported in >20% of patients undergoing shoulder arthroscopy in the sitting position under interscalene block anesthesia. Retrospective studies suggest that the administration of beta-blockers is safe and may decrease the incidence of thes...

journal_title：Anesthesia and analgesia

authors： Liguori GA,Kahn RL,Gordon J,Gordon MA,Urban MK

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Postpartum depression (PPD) is associated with pain during and after delivery, with studies showing reduced rates among women delivering with labor epidural analgesia (LEA). We hypothesized that women who intend to deliver with LEA but do not receive it are at higher risk for PPD at 6 weeks due to the combin...

journal_title：Anesthesia and analgesia

authors： Orbach-Zinger S,Landau R,Harousch AB,Ovad O,Caspi L,Kornilov E,Ioscovich A,Bracco D,Davis A,Fireman S,Hoshen M,Eidelman LA

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Every facility that performs cases on holidays has in some way decided on its operating room (OR) and anesthesia staffing for holidays. Previous studies have not examined how best to calculate appropriate holiday staffing. METHODS:We analyzed weekend and holiday data from a university hospital. RESULTS:The...

journal_title：Anesthesia and analgesia

authors： Dexter F,Epstein RH

更新日期：2006-12-01 00:00:00

abstract：:The aim of this study was to determine the need for supplemental oxygen during recovery from general anesthesia for ambulatory surgery in healthy women without obesity or respiratory disease. Arterial oxygen saturation by pulse oximetry (SpO2) was monitored throughout the first postoperative hour in 164 patients. The ...

journal_title：Anesthesia and analgesia

authors： Murray RS,Raemer DB,Morris RW

更新日期：1988-10-01 00:00:00

abstract：UNLABELLED:Apparently large plasma volumes derived by indocyanine green (PV-ICG) have been determined in the initial period after induction of anesthesia. We tested the hypothesis that possible overestimation of PV-ICG occurs shortly after anesthetic induction. Anesthesia was induced in 13 patients with fentanyl bolus ...

journal_title：Anesthesia and analgesia

authors： Mi WD,Ishihara H,Sakai T,Matsuki A

更新日期：2003-11-01 00:00:00

abstract：:These experiments investigated the effect of halothane or fentanyl anesthesia on plasma atrial natriuretic polypeptide (ANP) and angiotensin II (AII) concentrations and the response to a 30% blood volume load in rats. Halothane (1.1% and 2.2% inspired) or fentanyl (50 and 200 micrograms/kg) anesthesia alone produced l...

journal_title：Anesthesia and analgesia

authors： Hoffman WE,Phillips MI,Kimura B

更新日期：1989-01-01 00:00:00

abstract：:In the perioperative period, artificial colloids are most often infused in doses of 500-1000 mL intravenously. This randomized study compared the effects on intravascular volume and coagulation of approximately 2000 mL of two isooncotic artificial colloids: 6% hydroxyethyl starch (HES; MW 200,000; substitution ratio 0...

journal_title：Anesthesia and analgesia

authors： Mortelmans YJ,Vermaut G,Verbruggen AM,Arnout JM,Vermylen J,Van Aken H,Mortelmans LA

更新日期：1995-12-01 00:00:00

abstract：:Fifty-three swine from the University of Missouri Sinclair Medical Research Farm were used in experimentation to determine their susceptibility to malignant hyperthermia, to determine appropriate anesthetic agents for susceptible swine and to investigate appropriate pharmaceutical agents which could protect against th...

journal_title：Anesthesia and analgesia

authors： Short CE,Paddleford RR,McGrath CJ,Williams CH

更新日期：1976-09-01 00:00:00

abstract：UNLABELLED:We investigated the possibility of using argon, an inert gas, as a replacement for carbon dioxide (CO2). The tolerance of argon pneumoperitoneum was compared with that of CO2 pneumoperitoneum. Twenty pigs were anesthetized with enflurane 1.5%. Argon (n = 11) or CO2 (n = 9) pneumoperitoneum was created at 15 ...

journal_title：Anesthesia and analgesia

authors： Mann C,Boccara G,Grevy V,Navarro F,Fabre JM,Colson P

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:The status of neuropathic pain alters the responsiveness to formalin injection in rats. However, the mechanism by which this alteration occurs is unknown. METHODS:We used immunocytochemistry to examine the expression of brain-derived neurotrophic factor (BDNF) and calcitonin gene-related peptide (CGRP) in t...

journal_title：Anesthesia and analgesia

authors： Kaku R,Yokoyama M,Kobayashi H,Matsuoka Y,Sato T,Mizobuchi S,Itano Y,Morita K

更新日期：2007-04-01 00:00:00

abstract：:Successful procedural sedation represents a spectrum of patient- and clinician-related goals. The absence of a gold-standard measure of the efficacy of procedural sedation has led to a variety of outcomes being used in clinical trials, with the consequent lack of consistency among measures, making comparisons among tr...

journal_title：Anesthesia and analgesia

authors： Williams MR,McKeown A,Dexter F,Miner JR,Sessler DI,Vargo J,Turk DC,Dworkin RH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Ten to fifteen percent of awake patients develop neurological deficits secondary to cerebral hypoperfusion after carotid artery cross-clamping. The reversal of such deficits by increasing the inspired oxygen fraction (Fio(2)) has been demonstrated, and regional cerebral oxygenation (rSO(2)) has been shown to...

journal_title：Anesthesia and analgesia

authors： Picton P,Chambers J,Shanks A,Dorje P

更新日期：2010-02-01 00:00:00

abstract：:The correlation between the potency of inhaled anesthetics and their solubility in a hydrophobic phase provides an opportunity to define better the characteristics of the anesthetic site of action. The correlation implies that inhaled anesthetics act in a hydrophobic site and that the solvent used has properties repre...

journal_title：Anesthesia and analgesia

authors： Taheri S,Halsey MJ,Liu J,Eger EI 2nd,Koblin DD,Laster MJ

更新日期：1991-05-01 00:00:00

abstract：UNLABELLED:The transient hyperemic response (THR) test has been used to assess cerebral autoregulation in anesthesia and intensive care. To date it has not been compared with the static autoregulation test for assessing graded changes in cerebral autoregulation. We compared the two tests during propofol, desflurane, an...

journal_title：Anesthesia and analgesia

authors： Tibble RK,Girling KJ,Mahajan RP

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:In patients with mitral regurgitation (MR), the effective regurgitant orifice area can be estimated by measuring the vena contracta area (VCA). We hypothesize that the VCA has characteristic temporal dynamics related to the underlying mechanism of functional mitral regurgitation (FMR) versus degenerative mit...

journal_title：Anesthesia and analgesia

authors： Cobey FC,Ashihkmina E,Edrich T,Fox J,Shook D,Bollen B,Breeze JL,Ursprung WW,Shernan SK

更新日期：2016-02-01 00:00:00

abstract：:Noma (cancrum oris) is a disease of poverty and malnutrition, which predominantly affects children younger than 10 years in developing countries. Although the majority of sufferers die of sepsis at the time of the initial infection, or of subsequent starvation due to severe trismus and an inability to eat, a small min...

journal_title：Anesthesia and analgesia

authors： Coupe MH,Johnson D,Seigne P,Hamlin B

更新日期：2013-07-01 00:00:00

abstract：:An in vitro model was used to determine the force required to pierce bovine dura with a range of new spinal needles and to measure the subsequent leakage rate of cerebrospinal fluid (CSF). A significantly greater force was required to pierce the dura with pencil-point style needles compared to Quincke needles of the s...

journal_title：Anesthesia and analgesia

authors： Westbrook JL,Uncles DR,Sitzman BT,Carrie LE

更新日期：1994-10-01 00:00:00

abstract：:Cimetidine blunts the increase in cerebral blood flow (CBF) normally observed during hypoxia. It is important, therefore, to know whether other H2-blockers also affect the cerebral circulation adaptation to hypoxia. Cerebral blood flow was measured in 24 awake dogs after an intravenous injection of either saline (cont...

journal_title：Anesthesia and analgesia

authors： Audibert G,Saunier C,Hartemann D,Bigard O,Haberer JP

更新日期：1991-04-01 00:00:00