What solvent best represents the site of action of inhaled anesthetics in humans, rats, and dogs?

abstract：:Morphine plasma concentrations were determined in six patients receiving kidney transplants from living-related donors, and nine patients receiving kidney transplants from cadavers. The total cold ischemic time was about 2 hr for kidneys from living-related donors and 14 hr for those from cadavers. After an intravenou...

journal_title：Anesthesia and analgesia

authors： Sear J,Moore A,Hunniset A,Baldwin D,Allen M,Hand C,McQuay H,Morris P

更新日期：1985-11-01 00:00:00

abstract：UNLABELLED:We conducted this retrospective study to document the efficacy and safety, and demonstrate the spectrum of indications for subcutaneously tunneled epidural catheters in the management of prolonged pain in pediatric patients. The charts of 25 patients with prolonged pain that was unresponsive to conventional ...

journal_title：Anesthesia and analgesia

authors： Aram L,Krane EJ,Kozloski LJ,Yaster M

更新日期：2001-06-01 00:00:00

abstract：UNLABELLED:The adenosine triphosphate (ATP)-sensitive potassium channels (K(+)-ATP channels) are activated by decreases in intracellular ATP and help to match blood flow to tissue needs. Such metabolism-flow coupling occurs predominantly in the smallest arterioles measuring 50 microm or less in diameter. Previous studi...

journal_title：Anesthesia and analgesia

authors： Park KW,Dai HB,Comunale ME,Gopal A,Sellke FW

更新日期：2000-07-01 00:00:00

abstract：UNLABELLED:With the development of new computer-assisted target-controlled infusion (TCI) systems and the availability of short-acting anesthetics, total IV anesthesia (TIVA) has become increasingly popular. The aim of this study was to compare costs of TCI-based anesthesia with two standard anesthesia regimens. Sixty ...

journal_title：Anesthesia and analgesia

authors： Suttner S,Boldt J,Schmidt C,Piper S,Kumle B

更新日期：1999-01-01 00:00:00

abstract：:One of the most important physical properties affecting the level of analgesia achieved after intrathecal administration of a local anesthetic is its density relative to the density of the cerebrospinal fluid (CSF) at 37 degrees C. In this study, density, specific gravity, and baricity of local anesthetic solutions at...

journal_title：Anesthesia and analgesia

authors： Horlocker TT,Wedel DJ

更新日期：1993-05-01 00:00:00

abstract：UNLABELLED:We studied the effect of fluvoxamine and erythromycin on the pharmacokinetics of ropivacaine in a double-blinded, randomized, four-way cross-over study. Eight healthy volunteers ingested daily 1500 mg erythromycin for 6 days, 100 mg fluvoxamine for 5 days (Days 2-6), both erythromycin and fluvoxamine, or pla...

journal_title：Anesthesia and analgesia

authors： Jokinen MJ,Ahonen J,Neuvonen PJ,Olkkola KT

更新日期：2000-11-01 00:00:00

abstract：UNLABELLED:One thousand questionnaires concerning the techniques and complications of intravenous regional anesthesia (IVRA) were sent to 900 American and 100 Canadian anesthesiologists. Of the 321 respondents, 86% perform IVRA regularly. A wide variation in device-related and clinical aspects was found, ranging from a...

journal_title：Anesthesia and analgesia

authors： Henderson CL,Warriner CB,McEwen JA,Merrick PM

更新日期：1997-10-01 00:00:00

abstract：:To assess the evolution of satisfactory neohepatic graft function or failure, hemodynamic variables, along with data for oxygen delivery and utilization, were analyzed retrospectively in 99 patients undergoing orthotopic liver transplantation. Caval cross-clamping without venovenous bypass initiated a series of hemody...

journal_title：Anesthesia and analgesia

authors： Steltzer H,Hiesmayr M,Tüchy G,Zimpfer M

更新日期：1993-03-01 00:00:00

abstract：:Epidural anesthesia may be performed as a single injection or by staged doses. Thirty patients undergoing primary total hip replacement were randomly assigned to have epidural anesthesia using a single injection or a staged technique with 25 mL of 0.75% bupivacaine. Arterial plasma bupivacaine concentrations were sign...

journal_title：Anesthesia and analgesia

authors： Sharrock NE,Mineo R,Stanton J,Ennis WJ 3rd,Urmey WF,Arthur GR

更新日期：1994-08-01 00:00:00

abstract：:Elevated serum ammonia may play a role in central nervous system derangement after transurethral resection of the prostate. Glycine used as a surgical irrigant for prostate resection produces ammonia as a by-product after liver and renal metabolism. The presence of liver dysfunction often leads to an inability to remo...

journal_title：Anesthesia and analgesia

authors： Frink EJ Jr,DiGiovanni DA,Davis JR,Brown BR Jr

更新日期：1989-12-01 00:00:00

abstract：:Despite the exhaustive search for an acceptable substitute to erythrocyte transfusion, neither chemical-based products such as perfluorocarbons nor hemoglobin-based oxygen carriers have succeeded in providing a reasonable alternative to allogeneic blood transfusion. However, there remain scenarios in which blood trans...

journal_title：Anesthesia and analgesia

authors： Jahr JS,Guinn NR,Lowery DR,Shore-Lesserson L,Shander A

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:In this pilot study, we hypothesized that velocity parameters obtained from changes in clot amplitude (A) and clot elasticity (E) measured with thromboelastometry (ROTEM, Tem International GmbH, Munich, Germany) could improve detection of fibrinolysis in whole blood obtained from children undergoing surgery ...

journal_title：Anesthesia and analgesia

authors： Faraoni D,Van der Linden P,Ducloy-Bouthors AS,Goobie SM,DiNardo JA,Nielsen VG

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Previous studies show that the potent, prototypical sigma(1)-receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) prevents cell death after oxygen-glucose deprivation (OGD) in primary cortical neuronal cultures. We tested the hypothesis that PPBP protects neurons by a mechanism involving activation ...

journal_title：Anesthesia and analgesia

authors： Yang S,Alkayed NJ,Hurn PD,Kirsch JR

更新日期：2009-03-01 00:00:00

abstract：UNLABELLED:Epidural catheters (EC) are often used in pediatric patients for intraoperative and postoperative pain relief. The small anatomical structures and catheter insertion under general anesthesia make it more difficult to perform EC and to prevent damage. In this study we investigated the use of ultrasound (US) i...

journal_title：Anesthesia and analgesia

authors： Rapp HJ,Folger A,Grau T

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:In this study, we sought to determine whether a simplified ultrasound measurement of the largest transverse diameter, using a standard ultrasound machine, could be used to diagnose postoperative urinary retention (POUR). This method may replace expensive bladder volume measuring devices or a more complex ult...

journal_title：Anesthesia and analgesia

authors： Daurat A,Choquet O,Bringuier S,Charbit J,Egan M,Capdevila X

更新日期：2015-05-01 00:00:00

abstract：UNLABELLED:The aim of this study was to examine the antiallodynic and antinociceptive effects of subcutaneously administered physostigmine (50, 100, 200 micrograms/kg), compared with morphine (2.5, 5, 10 mg/kg) and NaCl after spinal nerve ligation in rats. The following stimuli were used: acetone (cold allodynia), von ...

journal_title：Anesthesia and analgesia

authors： Pöyhiä R,Xu M,Kontinen VK,Paananen S,Kalso E

更新日期：1999-08-01 00:00:00

abstract：INTRODUCTION:The mechanisms by which mechanical ventilation (MV) can injure remote organs, such as the kidney, remain poorly understood. We hypothesized that upregulation of systemic inflammation, as reflected by plasma interleukin-6 (IL-6) levels, in response to a lung-injurious ventilatory strategy, ultimately result...

journal_title：Anesthesia and analgesia

authors： Kuiper JW,Versteilen AM,Niessen HW,Vaschetto RR,Sipkema P,Heijnen CJ,Groeneveld AB,Plötz FB

更新日期：2008-10-01 00:00:00

abstract：:Fifteen critically ill patients with acute respiratory failure were ventilated with high-frequency jet ventilation (HFJV; frequency 100 breaths/min; I/E ratio 0.43; 1.8-mm internal diameter injector cannula). The patients were divided into two groups according to their initial PaO2 during intermittent positive pressur...

journal_title：Anesthesia and analgesia

authors： Benhamou D,Ecoffey C,Rouby JJ,Fusciardi J,Viars P

更新日期：1984-01-01 00:00:00

abstract：:The effects of continuous epidural anesthesia and of general anesthesia on the incidence of thromboembolism following total hip replacement were studied. Sixty patients were randomly allotted to one of two groups receiving either epidural or general anesthesia. Epidural anesthesia (N = 30) consisted of 0.5% bupivacain...

journal_title：Anesthesia and analgesia

authors： Modig J,Borg T,Karlström G,Maripuu E,Sahlstedt B

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:We determined the sensitivity of motor responses evoked by stimulating catheters in determining catheter-nerve contact using ultrasonography as reference. METHODS:Femoral nerves were contacted using stimulating catheters under ultrasonography scanning in 25 patients. The output current was increased from it...

journal_title：Anesthesia and analgesia

authors： Altermatt FR,Corvetto MA,Venegas C,Echevarría G,Bravo P,De la Cuadra JC,Irribarra LA

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The inflated costs and documented deleterious effects of excess perioperative transfusion have led to the investigation of targeted coagulation factor replacement strategies. One particular coagulation factor of interest is factor I (fibrinogen). Hypofibrinogenemia is typically tested for using time-consumin...

journal_title：Anesthesia and analgesia

authors： Fabbro M 2nd,Gutsche JT,Miano TA,Augoustides JG,Patel PA

更新日期：2016-09-01 00:00:00

abstract：:Cimetidine blunts the increase in cerebral blood flow (CBF) normally observed during hypoxia. It is important, therefore, to know whether other H2-blockers also affect the cerebral circulation adaptation to hypoxia. Cerebral blood flow was measured in 24 awake dogs after an intravenous injection of either saline (cont...

journal_title：Anesthesia and analgesia

authors： Audibert G,Saunier C,Hartemann D,Bigard O,Haberer JP

更新日期：1991-04-01 00:00:00

abstract：:We present a case of extreme hemodilution in which appropriately crossmatched blood was not available. A 53-year-old man was admitted to our hospital because of hemorrhagic shock due to multiple stab wounds. His blood type was B, Rh negative, and his intravascular fluid volume was maintained with balanced salt solutio...

journal_title：Anesthesia and analgesia

authors： Dai J,Tu W,Yang Z,Lin R

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Isoflurane activates vascular adenosine triphosphate sensitive potassium (K(ATP)) channels, and may induce vasodilation. In the present study, we investigated whether hyperglycemia modifies isoflurane activation of vascular K(ATP) channel. METHODS:We used a cell-attached patch-clamp configuration to test th...

journal_title：Anesthesia and analgesia

authors： Kawano T,Tanaka K,Mawatari K,Oshita S,Takahashi A,Nakaya Y

更新日期：2008-03-01 00:00:00

abstract：:The effects of nitrous oxide-oxygen plus small doses of fentanyl with (N = 7) and without (N = 15) naloxone and the effects of nitrous oxide-oxygen plus halothane (N = 13) on plasma concentration of arginine vasopressin (AVP) and cortisol were studied in normal patients before and during gynecologic laparotomies. Pati...

journal_title：Anesthesia and analgesia

authors： Lehtinen AM,Fyhrquist F,Kivalo I

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Implementation of initiatives to increase anesthesia group productivity depends not just on anesthesia groups, but on operating room (OR) nursing administration. OR nursing directors may encourage organizational change based on the needs of their hospitals and nurses. These changes may differ from those that...

journal_title：Anesthesia and analgesia

authors： Masursky D,Dexter F,Nussmeier NA

更新日期：2008-12-01 00:00:00

abstract：:We studied 60 nonophthalmologic patients, allocated to six treatment groups, to assess the effects of atracurium and vecuronium on intraocular pressure (IOP). All patients had IOP measured while awake, using pneumotonometry. In group 1, anesthesia was induced with thiopental, 5 mg/kg, and maintained with N2O, 70% in O...

journal_title：Anesthesia and analgesia

authors： Schneider MJ,Stirt JA,Finholt DA

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:In this study, we compared the effect of light sedation with remifentanil versus propofol on intracranial (ICP) and cerebral perfusion pressure (CPP) of patients undergoing stereotactic brain tumor biopsy under regional anesthesia. METHODS:This was a prospective, open-label, randomized, and controlled study...

journal_title：Anesthesia and analgesia

authors： Girard F,Moumdjian R,Boudreault D,Chouinard P,Bouthilier A,Ruel M

更新日期：2009-07-01 00:00:00

abstract：:We built and tested a combined proportional/derivative and minimum variance adaptive control algorithm for the regulation of blood pressure using sodium nitroprusside (SNP). In ten dogs the pressure was reduced by 30 mm Hg for 1 hr. The blood pressure came to within 5 mm Hg of the desired pressure in 1.7 +/- 4 min and...

journal_title：Anesthesia and analgesia

authors： Meline LJ,Westenskow DR,Pace NL,Bodily MN

更新日期：1985-01-01 00:00:00

abstract：:A combination of pancuronium and d-tubocurarine is associated with potentiation of the neuromuscular blocking effects of each drug used singly. The time to onset of maximum block and the time to 25% recovery after administration of equipotent (ED95) doses of pancuronium (0.07 mg/kg) alone, d-tubocurarine (0.51 mg/kg) ...

journal_title：Anesthesia and analgesia

authors： Mirakhur RK,Pandit SK,Ferres CJ,Gibson FM

更新日期：1984-04-01 00:00:00