Halothane enhances pulmonary artery endothelial eicosanoid release.

abstract：BACKGROUND:Dexmedetomidine, an α(2)-receptor agonist, prolongs analgesia when used in neuraxial and IV blocks. We evaluated the effect of dexmedetomidine added to ropivacaine for tibial nerve block on the duration of the sensory blockade. METHODS:For this prospective, randomized, controlled, double-blind, crossover tr...

journal_title：Anesthesia and analgesia

authors： Rancourt MP,Albert NT,Côté M,Létourneau DR,Bernard PM

更新日期：2012-10-01 00:00:00

abstract：:The effects of ropivacaine, a new amide local anesthetic, on uterine blood flow and fetal well-being were compared with those of bupivacaine in 10 chronically instrumented pregnant ewes. In random sequence, animals received two intravenous infusions of each drug. The low infusion rate regimens were chosen to result in...

journal_title：Anesthesia and analgesia

authors： Santos AC,Arthur GR,Roberts DJ,Wlody D,Pedersen H,Morishima HO,Finster M,Covino BG

更新日期：1992-01-01 00:00:00

abstract：UNLABELLED:Because perfluorocarbon (PFC) liquid contacts closely with the alveolar capillaries during partial liquid ventilation (PLV), PLV with cold PFC may be used for the induction of hypothermia. Twenty rabbits were randomized to PFC-induced hypothermia (PH) (n = 7; core temperature 35 degrees +/- 1 degrees C), sur...

journal_title：Anesthesia and analgesia

authors： Hong SB,Koh Y,Shim TS,Lee SD,Kim WS,Kim DS,Kim WD,Lim CM

更新日期：2002-01-01 00:00:00

abstract：UNLABELLED:Surgery causes changes in hemostasis, leading to a hypercoagulable state that has been linked to both arterial and venous thrombotic complications. The etiology of this state is unknown, but many investigators have hypothesized that perioperative neuroendocrine changes are responsible. We have previously dem...

journal_title：Anesthesia and analgesia

authors： Rosenfeld BA,Nguyen ND,Sung I,Faraday N

更新日期：1998-03-01 00:00:00

abstract：:The Brandt tube system can limit excessive cuff pressure during nitrous oxide (N(2)O) anesthesia, but there is a lack of data assessing whether the Brandt tube system avoids cuff deflation after cessation of N(2)O administration. In this study, we recorded air-filled cuff pressures of the Mallinckrodt Brandt or Hi-Con...

journal_title：Anesthesia and analgesia

authors： Karasawa F,Takita A,Mori T,Takamatsu I,Kawatani Y,Oshima T

更新日期：2003-02-01 00:00:00

abstract：UNLABELLED:Because inhibition of voltage-dependent Ca(2+) channels can be a mechanism underlying general anesthesia, we examined sensitivities to propofol and halothane in mice lacking the R-type (Ca(v)2.3) channel widely expressed in neurons. Sleep time after propofol injection (26 mg/kg IV) and halothane MAC(RR) and ...

journal_title：Anesthesia and analgesia

authors： Takei T,Saegusa H,Zong S,Murakoshi T,Makita K,Tanabe T

更新日期：2003-07-01 00:00:00

abstract：:In in vitro pharmacological experiments, determination of effective concentration values for various anesthetics depends on understanding the exact concentration of the drugs dissolved in physiological solutions. Actual anesthetic concentration may differ from expectations because of drug adsorption, absorption or oth...

journal_title：Anesthesia and analgesia

authors： Suzuki T,Uchida I,Mashimo T

更新日期：2005-02-01 00:00:00

abstract：IMPLICATIONS:Misplacement of an epidural catheter into the subarachnoid space is a recognized complication. However, breakage of an intrathecal epidural catheter during removal presents a dilemma. Appropriate imaging, a neurosurgical consultation, and aggressive surgical exploration and extraction of the retained piece...

journal_title：Anesthesia and analgesia

authors： Ugboma S,Au-Truong X,Kranzler LI,Rifai SH,Joseph NJ,Salem MR

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:The presence of an endotracheal tube is the main cause for developing ventilator-associated pneumonia (VAP), but pneumonia can still develop in hospitalized patients after endotracheal tube removal (postextubation pneumonia [PEP]). We hypothesized that short-term intubation (24 hours) can play a role in the ...

journal_title：Anesthesia and analgesia

authors： Rezoagli E,Zanella A,Cressoni M,De Marchi L,Kolobow T,Berra L

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) is a commonly encountered comorbid condition in patients undergoing surgery and is associated with a greater risk of postoperative adverse events. Our objective in this review was to investigate the effectiveness of continuous positive airway pressure (CPAP) in reducing the risk...

journal_title：Anesthesia and analgesia

authors： Nagappa M,Mokhlesi B,Wong J,Wong DT,Kaw R,Chung F

更新日期：2015-05-01 00:00:00

abstract：:Dexmedetomidine hydrochloride is a potent, highly selective alpha-2 adrenergic receptor agonist, broadly used as a sedative drug in intensive care units. We describe the case of a 59-yr-old patient who experienced drug fever caused by dexmedetomidine hydrochloride. The patient was transferred to the intensive care uni...

journal_title：Anesthesia and analgesia

authors： Okabe T,Takeda S,Akada S,Hongo T,Sakamoto A

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:In children, the laryngeal mask airway (LMA) is frequently displaced within the hypopharynx, resulting in repositioning of the device. When the tip of the LMA is placed in the esophageal inlet, the arytenoids are moved ventrally. When the LMA is rotated or deviated, the ventral movement of the arytenoids may...

journal_title：Anesthesia and analgesia

authors： Kim J,Kim JY,Kim WO,Kil HK

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:As the use of pulse oximeters increases, the needs for higher performance and wider applicability of pulse oximetry have increased. To realize the full potential of pulse oximetry, it is indispensable to increase the number of optical wavelengths. To develop a multiwavelength oximetry system, a physical theo...

journal_title：Anesthesia and analgesia

authors： Aoyagi T,Fuse M,Kobayashi N,Machida K,Miyasaka K

更新日期：2007-12-01 00:00:00

abstract：UNLABELLED:In this study, we examined the effectiveness of caudal blocks and correlated it with the laxity of the patients' anal sphincter before emergence from anesthesia in 178 children undergoing inguinal and/or penile surgery. Bupivacaine 0.25% in a volume of 0.6-1.25 mL/kg was used in all patients. The presence of...

journal_title：Anesthesia and analgesia

authors： Verghese ST,Mostello LA,Patel RI,Kaplan RF,Patel KM

更新日期：2002-05-01 00:00:00

abstract：UNLABELLED:In this retrospective cohort study, we compared adverse cardiac outcomes after noncardiac surgery among patients with prior percutaneous transluminal coronary angioplasty (PTCA), patients with nonrevascularized coronary artery disease (CAD), and normal controls. Inpatient hospital discharge abstracts from al...

journal_title：Anesthesia and analgesia

authors： Posner KL,Van Norman GA,Chan V

更新日期：1999-09-01 00:00:00

abstract：UNLABELLED:Previous reports indicate that cyclosporine increases sleeping time from barbiturate administration, and analgesia from fentanyl administration, suggesting a possible contribution of cyclosporine to anesthesia. Accordingly, we determined whether cyclosporine pretreatment decreases isoflurane MAC (the minimum...

journal_title：Anesthesia and analgesia

authors： Niemann CU,Stabernack C,Serkova N,Jacobsen W,Christians U,Eger EI 2nd

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Endotracheal tubes (ETTs) are commonly secured with tape to prevent undesirable tube migration. Many methods of taping have been described, although little has been published comparing various methods of taping to one another. In this study, we evaluated several methods for securing ETTs with tape. We hypoth...

journal_title：Anesthesia and analgesia

authors： Matchett G,Yang JH,Sripathi NR,Simpkins L,Ruikar K,Minhajuddin A,Whitten CW

更新日期：2020-08-01 00:00:00

abstract：:A series of 50 combat-injured patients given crash intubation for rapid induction of anesthesia is presented. The technic consisted of injection of 3 mg of d-tubocurarine and 0.4 mg of atropine IV, preoxygenation by face mask for 3 minutes, and then injection of sodium thiopental or ketamine, followed immediately by 6...

journal_title：Anesthesia and analgesia

authors： Cromartie RS 3rd

更新日期：1976-01-01 00:00:00

abstract：:Ondansetron and droperidol are both effective in the prevention of postoperative nausea and vomiting (PONV). In this randomized, double-blind study, 80 inpatients scheduled for minor gynecologic surgery received either ondansetron 8 mg intravenously (i.v.) or droperidol 2.5 mg i.v. 5 min prior to induction of isoflura...

journal_title：Anesthesia and analgesia

authors： Grond S,Lynch J,Diefenbach C,Altrock K,Lehmann KA

更新日期：1995-09-01 00:00:00

abstract：:In order to evaluate the possible physiologic significance of intra- and postoperative hypotension, we monitored arterial blood pressure and heart rate continuously for 36 hr starting the night before and ending the morning after operation in 34 gynecologic patients. The lowest pressures that occurred during physiolog...

journal_title：Anesthesia and analgesia

authors： Berger JJ,Donchin M,Morgan LS,van der Aa J,Gravenstein JS

更新日期：1984-07-01 00:00:00

abstract：:Epidural clonidine produces analgesia in humans with acute and chronic pain. Its use is limited because of short-lasting analgesia, hemodynamic depression, sedation, and respiratory depression. Intrathecal guanfacine has a longer duration of action than intrathecal clonidine. The present study compares these two drugs...

journal_title：Anesthesia and analgesia

authors： Smith BD,Baudendistel LJ,Gibbons JJ,Schweiss JF

更新日期：1992-05-01 00:00:00

abstract：:We tested whether anesthesia that includes nitrous oxide (N2O) results in the development of intraoperative and postoperative pulmonary complications, including hypoxemia. We also tested whether aging contributes to the development of such complications, particularly when anesthesia includes N2O. We randomly allocated...

journal_title：Anesthesia and analgesia

authors： Lampe GH,Wauk LZ,Whitendale P,Way WL,Kozmary SV,Donegan JH,Eger EI 2nd

更新日期：1990-12-01 00:00:00

abstract：:A microelectrode examination of guinea pig left ventricular papillary muscle was performed to determine whether there was a direct effect of pancuronium on cardiac cells and, if so, to attempt to ascertain the mechanism of this effect. Electrical events were measured before and during superfusion with pancuronium, epi...

journal_title：Anesthesia and analgesia

authors： Jacobs HK,Lim S,Salem MR,Rao TL,Mathru M,Smith BD

更新日期：1985-07-01 00:00:00

abstract：:Prior studies have suggested that the antifibrinolytic drug aprotinin increases the infarct size after ischemia and reperfusion (I/R) and attenuates the effect of ischemic preconditioning (IPC). Aprotinin was replaced by tranexamic acid (TXA) in clinical practice. Here, we investigated whether TXA influences I/R injur...

journal_title：Anesthesia and analgesia

authors： van Caster P,Eiling S,Boekholt Y,Behmenburg F,Dorsch M,Heinen A,Hollmann MW,Huhn R

更新日期：2018-02-01 00:00:00

abstract：:Colloids and crystalloids are usually administered as treatment for hypovolemia in severely injured patients. However, dilution of clotting factors and platelets together with impaired fibrinogen polymerization are associated with fluid therapy and may aggravate hemorrhage, thus worsening final outcome of these patien...

journal_title：Anesthesia and analgesia

authors： Fries D,Innerhofer P,Reif C,Streif W,Klingler A,Schobersberger W,Velik-Salchner C,Friesenecker B

更新日期：2006-02-01 00:00:00

abstract：:Adverse reactions to volatile anesthetics and depolarizing muscle relaxants can occur in patients with Duchenne muscular dystrophy (DMD) resulting in acute rhabdomyolysis and hyperkalemia. We report a case of hyperkalemic cardiac arrest after cardiac surgery using cardiopulmonary bypass in a child with unsuspected DMD...

journal_title：Anesthesia and analgesia

authors： Nathan A,Ganesh A,Godinez RI,Nicolson SC,Greeley WJ

更新日期：2005-03-01 00:00:00

abstract：:The electroencephalograms of seven elderly (70-85 years) and seven younger patients (23-31 years) anesthetized with a concentration of isoflurane sufficient to produce burst suppression were studied. Anesthesia in these unpremedicated subjects was induced by inhalation of nitrous oxide, isoflurane, and oxygen. Trachea...

journal_title：Anesthesia and analgesia

authors： Schwartz AE,Tuttle RH,Poppers PJ

更新日期：1989-01-01 00:00:00

abstract：:There are recent concerns that anesthesiologists are becoming less skilled in providing general anesthesia for Cesarean delivery. We considered whether a verbal checklist would help in the preparation for this event. We created a list of items to be checked when preparing to administer general anesthesia for a Cesarea...

journal_title：Anesthesia and analgesia

authors： Hart EM,Owen H

更新日期：2005-07-01 00:00:00

abstract：:Cytokine release during surgery can produce a long-lasting hyperalgesia. Thus, preoperatively-administered cytokine inhibitors might reduce the production of cytokines, decreasing central nervous system sensitization and improving the quality of postoperative pain relief. We investigated the hypothesis that preincisio...

journal_title：Anesthesia and analgesia

authors： Lu CH,Chao PC,Borel CO,Yang CP,Yeh CC,Wong CS,Wu CT

更新日期：2004-11-01 00:00:00

abstract：:This research determined the safety and efficacy of two small-dose infusions of dexmedetomidine by evaluating sedation, analgesia, cognition, and cardiorespiratory function. Seven healthy young volunteers provided informed consent and participated on three occasions with random assignment to drug or placebo. Heart rat...

journal_title：Anesthesia and analgesia

authors： Hall JE,Uhrich TD,Barney JA,Arain SR,Ebert TJ

更新日期：2000-03-01 00:00:00