Multiwavelength pulse oximetry: theory for the future.

abstract：UNLABELLED:Morbidly obese (MO) patients undergoing laparoscopy have lower PaO(2) compared with normal-weight (NW) patients. We hypothesized that increases in tidal volume (V(T)) or respiratory rate (RR) would improve oxygenation. All measurements were performed at: 1) baseline: V(T) 600-700 mL and 10 breaths/min, 2) do...

journal_title：Anesthesia and analgesia

authors： Sprung J,Whalley DG,Falcone T,Wilks W,Navratil JE,Bourke DL

更新日期：2003-07-01 00:00:00

abstract：UNLABELLED:When opioids are used for postoperative pain control, it is useful to define the dose-response relationship for analgesia and respiratory depression. We studied 20 chronically opioid-consuming patients having elective multilevel spine fusion. Preoperatively, each patient received a fentanyl infusion of 2 mic...

journal_title：Anesthesia and analgesia

authors： Davis JJ,Swenson JD,Hall RH,Dillon JD,Johnson KB,Egan TD,Pace NL,Niu SY

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor alpha (TNF-alpha) could trigger p38 mitogen-activated protein kinase (MAPK) activation. Conversely phosphorylated p38 (p-p38) could induce the upregulation of TNF-alpha. In this study, we examined the hypothesis that chronic constrictive injury (CCI) of the sciatic nerve could promote s...

journal_title：Anesthesia and analgesia

authors： Xu L,Huang Y,Yu X,Yue J,Yang N,Zuo P

更新日期：2007-12-01 00:00:00

abstract：UNLABELLED:Systemically-administered morphine reduces infarct size in rat models of myocardial ischemia-reperfusion. We sought to determine whether much smaller doses of spinally-administered morphine offer a similar cardioprotective benefit. Barbiturate-anesthetized, open-chested, Wistar rats with chronic indwelling t...

journal_title：Anesthesia and analgesia

authors： Groban L,Vernon JC,Butterworth J

更新日期：2004-04-01 00:00:00

abstract：UNLABELLED:The enhancing action of propofol on gamma-amino-n-butyric acid subtype A (GABA(A)) receptors purportedly underlies its anesthetic effects. However, a recent study found that a GABA(A) antagonist did not alter the capacity of propofol to depress the righting reflex. We examined whether the noncompetitive GABA...

journal_title：Anesthesia and analgesia

authors： Sonner JM,Zhang Y,Stabernack C,Abaigar W,Xing Y,Laster MJ

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:In vivo animal assays are a cornerstone of preclinical pain research. An optimal stimulus for determining the activity of potential analgesics would produce responses of a consistent magnitude on repeated testing. Intraplantar (i.pl.) injection of hypertonic saline (HS) in mice produces robust nociceptive re...

journal_title：Anesthesia and analgesia

authors： Asiri YI,Fung T,Schwarz SKW,Barr AM,Puil E,MacLeod BA

更新日期：2019-07-01 00:00:00

abstract：:Patient-reported outcomes (PROs) are measures of health status that come directly from the patient. PROs are an underutilized tool in the perioperative setting. Enhanced recovery pathways (ERPs) have primarily focused on traditional measures of health care quality such as complications and hospital length of stay. The...

journal_title：Anesthesia and analgesia

authors： Abola RE,Bennett-Guerrero E,Kent ML,Feldman LS,Fiore JF Jr,Shaw AD,Thacker JKM,Gan TJ,Miller TE,Hedrick TL,McEvoy MD,Mythen MG,Bergamaschi R,Gupta R,Holubar SD,Senagore AJ,Wischmeyer PE,Carli F,Evans DC,Guilbert S,

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Unanticipated hospital admission is regarded as a measure of adverse perioperative patient care. However, previously published studies for risk prediction after ambulatory procedures are sparse compared to those examining readmission after inpatient surgery. We aimed to evaluate the incidence and reasons for...

journal_title：Anesthesia and analgesia

authors： Teja B,Raub D,Friedrich S,Rostin P,Patrocínio MD,Schneider JC,Shen C,Brat GA,Houle TT,Yeh RW,Eikermann M

更新日期：2020-08-01 00:00:00

abstract：UNLABELLED:Calcium-sensitizing drugs, such as levosimendan, are a novel class of drug therapy for heart failure. We investigated the hypothesis that levosimendan is a pulmonary vasodepressor mediated through inhibition of phosphodiesterase, adenosine triphosphate (ATP)-dependent potassium channels, or both. We investig...

journal_title：Anesthesia and analgesia

authors： De Witt BJ,Ibrahim IN,Bayer E,Fields AM,Richards TA,Banister RE,Kaye AD

更新日期：2002-06-01 00:00:00

abstract：:Halothane, enflurane, isoflurane, and fentanyl were examined for their potential to exacerbate liver dysfunction in rats with preexisting cirrhosis. Male Wistar rats given sodium phenobarbital for 2 weeks are assigned randomly to two groups. One group (cirrhotic) was exposed by inhalation to carbon tetrachloride (CCl4...

journal_title：Anesthesia and analgesia

authors： Baden JM,Kundomal YR,Luttropp ME Jr,Maze M,Kosek JC

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:The spinal cord is an important site where volatile anesthetics decrease sensation and produce immobility. Beyond this knowledge, our understanding of a site of anesthetic action is limited. Previous evidence suggests that dorsal horn neurons with ascending projections may be more susceptible to depression b...

journal_title：Anesthesia and analgesia

authors： Barter LS,Mark LO,Jinks SL,Carstens EE,Antognini JF

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether mechanically ventilated trauma patients with a positive urine drug screen (UDS) for cocaine and/or amphetamines have different opioid analgesic and sedative requirements compared with similar patients with a negative drug screen for these stimulants. METHOD...

journal_title：Anesthesia and analgesia

authors： Kram B,Kram SJ,Sharpe ML,James ML,Kuchibhatla M,Shapiro ML

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Performing key actions efficiently during crises can determine clinical outcomes, yet even expert clinicians omit key actions. Simulation-based studies of crises show that correct performance of key actions dramatically increases when emergency manuals (EMs) are used. Despite widespread dissemination of EMs,...

journal_title：Anesthesia and analgesia

authors： Goldhaber-Fiebert SN,Bereknyei Merrell S,Agarwala AV,De La Cruz MM,Cooper JB,Howard SK,Asch SM,Gaba DM

更新日期：2020-12-01 00:00:00

abstract：:The purpose of this study was to compare the perioperative effects of the intramuscular (i.m.) alpha 2 agonist, dexmedetomidine (DEX), and midazolam (MID) premedication. The study comprised 192 women (64 per group) scheduled for abdominal hysterectomy. The doses of the study drugs were chosen to obtain equal sedative ...

journal_title：Anesthesia and analgesia

authors： Erkola O,Korttila K,Aho M,Haasio J,Aantaa R,Kallio A

更新日期：1994-10-01 00:00:00

abstract：:The renal effects of pulsatile (pulse pressure 18.0 +/- 1.5 mm Hg [mean +/- SEM]) or nonpulsatile perfusion (mean pulse pressure 1.9 +/- 0.4 mm Hg) during either alpha-stat (mean PaCO2 41.2 +/- 0.9 mm Hg measured at 37 degrees C) or pH-stat (mean PaCO2 60.6 +/- 1.7 mm Hg measured at 37 degrees C) pH management of hypo...

journal_title：Anesthesia and analgesia

authors： Badner NH,Murkin JM,Lok P

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:The cerebral perfusion pressure that denotes the lower limit of cerebral blood flow autoregulation (LLA) is generally considered to be equivalent for reductions in arterial blood pressure (ABP) or increases in intracranial pressure (ICP). However, the effect of decreasing ABP at different levels of ICP has n...

journal_title：Anesthesia and analgesia

authors： Brady KM,Lee JK,Kibler KK,Easley RB,Koehler RC,Czosnyka M,Smielewski P,Shaffner DH

更新日期：2009-04-01 00:00:00

abstract：UNLABELLED:The aim of this study was to examine the antiallodynic and antinociceptive effects of subcutaneously administered physostigmine (50, 100, 200 micrograms/kg), compared with morphine (2.5, 5, 10 mg/kg) and NaCl after spinal nerve ligation in rats. The following stimuli were used: acetone (cold allodynia), von ...

journal_title：Anesthesia and analgesia

authors： Pöyhiä R,Xu M,Kontinen VK,Paananen S,Kalso E

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Percutaneous cannulation of the femoral vein, in the pediatric age group, can be technically challenging, especially when performed by residents in training. We examined whether the use of real-time ultrasound guidance is superior to a landmark technique for femoral vein catheterization in children undergoin...

journal_title：Anesthesia and analgesia

authors： Aouad MT,Kanazi GE,Abdallah FW,Moukaddem FH,Turbay MJ,Obeid MY,Siddik-Sayyid SM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Vital sign monitors and ventilator/anesthesia workstations are equipped with multiple alarms to improve patient safety. A high number of false alarms can lead to a "crying wolf" phenomenon with consecutively ignored critical situations. Systematic data on alarm patterns and density in the perioperative phase...

journal_title：Anesthesia and analgesia

authors： Schmid F,Goepfert MS,Kuhnt D,Eichhorn V,Diedrichs S,Reichenspurner H,Goetz AE,Reuter DA

更新日期：2011-01-01 00:00:00

abstract：:Migraine is a frequent neurological pathology. However, the diagnosis can be difficult to establish, especially when it is accompanied with an atypical aura that can be confounded with a stroke. We describe a case of 38-yr-old patient who presented just after general anesthesia with a perioperative acute migraine with...

journal_title：Anesthesia and analgesia

authors： Pianezza A,Barthélémy R,Minville V,Martin F,Faggianelli M

更新日期：2008-06-01 00:00:00

abstract：:Postoperative sore throat (POST), although a minor complication, remains a source of postoperative morbidity. We compared the efficacy of dispersible aspirin gargle to benzydamine hydrochloride (a topical nonsteroidal anti inflammatory drug) gargles for prevention of POST. We enrolled 60 consecutive female patients, 1...

journal_title：Anesthesia and analgesia

authors： Agarwal A,Nath SS,Goswami D,Gupta D,Dhiraaj S,Singh PK

更新日期：2006-10-01 00:00:00

abstract：:The pharmacokinetics of lidocaine were studied in nonpregnant and pregnant ewes. The maternal femoral vessels were cannulated and, on the day of study, the urinary bladder was catheterized. Lidocaine HCl, 4-5 mg/kg, was administered by IV injection over 60 seconds. Serial samples of arterial blood and urine were colle...

journal_title：Anesthesia and analgesia

authors： Santos AC,Pedersen H,Morishima HO,Finster M,Arthur GR,Covino BG

更新日期：1988-12-01 00:00:00

abstract：:A previous demonstration that the ratio of analgesic to anesthetic endpoints is not constant across inhalation anesthetic agents implies that more than one mechanism of action may be operant in general anesthesia. We hypothesized that the endogenous opiate systems might account for this observed disparity in ratios. T...

journal_title：Anesthesia and analgesia

authors： Levine LL,Winter PM,Nemoto EM,Uram M,Lin MR

更新日期：1986-04-01 00:00:00

abstract：:The diagnosis of adrenocortical insufficiency in critically ill patients is complex. The adrenocorticotropic hormone (ACTH) stimulation test is a widely accepted method for assessing the adequacy of adrenal function in intensive care units, but it is possible that there may be wide variations in responses to the test ...

journal_title：Anesthesia and analgesia

authors： Loisa P,Uusaro A,Ruokonen E

更新日期：2005-12-01 00:00:00

abstract：:Reactive oxygen species (ROS) are central to cardiac ischemic and reperfusion injury. They contribute to myocardial stunning, infarction and apoptosis, and possibly to the genesis of arrhythmias. Multiple laboratory studies and clinical trials have evaluated the use of scavengers of ROS to protect the heart from the e...

journal_title：Anesthesia and analgesia

authors： Kevin LG,Novalija E,Stowe DF

更新日期：2005-11-01 00:00:00

abstract：UNLABELLED:We studied the in vitro effects of sevoflurane, isoflurane, and propofol anesthesia on platelet function. Thirty patients undergoing minor surgical procedures were divided into three groups (n = 10 each). Induction of anesthesia was achieved by using 5 mg/kg thiopental i.v., and 0.1 mg/kg vecuronium i.v. was...

journal_title：Anesthesia and analgesia

authors： Doğan IV,Ovali E,Eti Z,Yayci A,Göğüş FY

更新日期：1999-02-01 00:00:00

abstract：:A technique combining an intravenous bolus and intravenous infusion regimen of gallamine based on its pharmacokinetics was developed to produce continuous relaxation during surgery. The combination of a bolus dose of gallamine, 2.5 mg/kg, and infusion, 0.8 mg/kg/hr, was tested in 11 patients. In 10 patients, surgery c...

journal_title：Anesthesia and analgesia

authors： Shanks CA,Funk DI,Avram MJ,Henthorn TK

更新日期：1982-10-01 00:00:00

abstract：IMPLICATIONS:Because of case reports of severe bronchospasm after the use of mivacurium, we used the Food and Drug Administration MedWatch database to determine the frequency of bronchospasm as an adverse event after the use of nondepolarizing muscle relaxants. ...

journal_title：Anesthesia and analgesia

authors： Bishop MJ,O'Donnell JT,Salemi JR

更新日期：2003-08-01 00:00:00

abstract：:The tandem pore domain K channel family mediates background K currents present in excitable cells. Currents passed by certain members of the family are enhanced by volatile anesthetics, thus suggesting a novel mechanism of anesthesia. The newest member of the family, termed TRESK (TWIK [tandem pore domain weak inward ...

journal_title：Anesthesia and analgesia

authors： Liu C,Au JD,Zou HL,Cotten JF,Yost CS

更新日期：2004-12-01 00:00:00

abstract：:In a laboratory experiment, the expected analgesic action of 33% nitrous oxide was reversed by creating the expectancy of heightened awareness of bodily sensations. Pain threshold and tolerance of electrical tooth-pulp stimulation were significantly reduced. Results from a control study gave us a basis for comparison ...

journal_title：Anesthesia and analgesia

authors： Dworkin SF,Chen AC,LeResche L,Clark DW

更新日期：1983-12-01 00:00:00