Potent activation of the human tandem pore domain K channel TRESK with clinical concentrations of volatile anesthetics.

abstract：UNLABELLED:We performed this study to assess the influence of endotracheal tube (ETT) tip design (Murphy-tip versus Magill-tip) on nasal trauma during nasotracheal intubation with a conventional polyvinyl chloride ETT. Patients were randomly allocated to one of four groups (n = 25 each): Magill-tipped ETT and Murphy-ti...

journal_title：Anesthesia and analgesia

authors： Lee JH,Kim CH,Bahk JH,Park KS

更新日期：2005-10-01 00:00:00

abstract：UNLABELLED:We examined how to program an operating room (OR) information system to assist the OR manager in deciding whether to move the last case of the day in one OR to another OR that is empty to decrease overtime labor costs. We first developed a statistical strategy to predict whether moving the case would decreas...

journal_title：Anesthesia and analgesia

authors： Dexter F

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Hydroxyethyl starch (HES) solution is characterized by its mean molecular weight (MW), concentration, and degree of substitution (DS). This character varies worldwide. METHODS:After binding fluorescein-isothiocyanate (FITC-HES), we evaluated the retention rate of three types of 6% HES in the A2 and V2 blood...

journal_title：Anesthesia and analgesia

authors： Hitosugi T,Saito T,Suzuki S,Kubota I,Shoda E,Shimizu T,Oi Y

更新日期：2007-09-01 00:00:00

abstract：:Although isoflurane can reduce ischemic neuronal injury after short postischemic recovery intervals, data from our laboratory have demonstrated that this neuroprotection is not sustained and that delayed apoptotic neuronal death, mediated in part by activation of caspases, contributes to the gradual increase in the si...

journal_title：Anesthesia and analgesia

authors： Inoue S,Davis DP,Drummond JC,Cole DJ,Patel PM

更新日期：2006-05-01 00:00:00

abstract：:A double-blind study comparing four narcotic analgesics of different potencies, meperidine, morphine, fentanyl, and sufentanil, was performed on consenting patients undergoing general or orthopedic surgery under balanced anesthesia. Blood pressure, measured through an indwelling arterial catheter, was recorded continu...

journal_title：Anesthesia and analgesia

authors： Flacke JW,Bloor BC,Kripke BJ,Flacke WE,Warneck CM,Van Etten AP,Wong DH,Katz RL

更新日期：1985-09-01 00:00:00

abstract：UNLABELLED:We investigated the role of cardiopulmonary bypass (CPB) in compromised lung function associated with cardiac surgery. Low-frequency respiratory impedance (Zrs) was measured in patients undergoing cardiac surgery with (n = 30; CPB group) or without (n = 29; off-pump coronary artery bypass [OPCAB] group) CPB....

journal_title：Anesthesia and analgesia

authors： Babik B,Asztalos T,Peták F,Deák ZI,Hantos Z

更新日期：2003-05-01 00:00:00

abstract：:The effects of gestational age (GA) and plasma protein concentrations on the plasma protein binding of fentanyl and alfentanil were studied in preterm and term neonates. Binding experiments were performed using split-cell equilibrium dialysis. Fentanyl and alfentanil concentrations were measured using specific radioim...

journal_title：Anesthesia and analgesia

authors： Wilson AS,Stiller RL,Davis PJ,Fedel G,Chakravorti S,Israel BA,McGowan FX Jr

更新日期：1997-02-01 00:00:00

abstract：UNLABELLED:Suppression of nitric oxide (NO) production alters the toxicity of cocaine and bupivacaine. We undertook this study to determine whether the systemic toxicity of two other local anesthetics that differ in antiarrhythmic activity, plasma clearance, and biotransformation are similarly affected by nitric oxide ...

journal_title：Anesthesia and analgesia

authors： Heavner JE,Shi B,Pitkänen M

更新日期：1999-04-01 00:00:00

abstract：UNLABELLED:Many drugs are tested intrathecally to investigate alternatives to opioids. We aimed to explore the analgesic and possible neurotoxic effects of chronic intrathecally-administered ketorolac tromethamine in rats. Catheters were placed via atlantoaxial interval in 28 Wistar rats under anesthesia of intraperito...

journal_title：Anesthesia and analgesia

authors： Korkmaz HA,Maltepe F,Erbayraktar S,Yilmaz O,Güray M,Canda MS,Günerli A,Gökmen N

更新日期：2004-01-01 00:00:00

abstract：UNLABELLED:This study was performed to evaluate both the effects of pentobarbital on disruption of the blood-brain barrier (BBB) by hyperosmolar mannitol and the relationship between its effect on blood pressure and the integrity of the BBB. Under isoflurane anesthesia, rats in the control group were infused with 25% m...

journal_title：Anesthesia and analgesia

authors： Chi OZ,Chun TW,Liu X,Weiss HR

更新日期：1998-06-01 00:00:00

abstract：:A 19-year-old African American man with a T12 spinal cord lesion underwent a T4-L5 thoracolumbar spinal fusion. Intraoperatively, his arterial blood pressure acutely increased from 110/60 to 260/130 mm Hg without a change in heart rate. The patient did not have pheochromocytoma, carcinoid syndrome, or thyroid storm. T...

journal_title：Anesthesia and analgesia

authors： Blacker SN,Brown CQ,Tarant NS

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The goal of this study was to determine a set of timing, shape, and statistical features available through noninvasive monitoring of maternal electrocardiogram and photoplethysmography that identifies preeclamptic patients. METHODS:Pregnant women admitted to Labor and Delivery were monitored with pulse oxim...

journal_title：Anesthesia and analgesia

authors： Euliano TY,Michalopoulos K,Singh S,Gregg AR,Del Rio M,Vasilopoulos T,Johnson AM,Onkala A,Darmanjian S,Euliano NR,Ho M

更新日期：2018-03-01 00:00:00

abstract：:In the past, it was common practice to use a high tidal volume (VT) during intraoperative ventilation, because this reduced the need for high oxygen fractions to compensate for the ventilation-perfusion mismatches due to atelectasis in a time when it was uncommon to use positive end-expiratory pressure (PEEP) in the o...

journal_title：Anesthesia and analgesia

authors： Hol L,Nijbroek SGLH,Schultz MJ

更新日期：2020-12-01 00:00:00

abstract：:Acute fatty liver of pregnancy (AFLP) is a late gestational complication with biochemical similarities to the inherited disorders of mitochondrial fatty acid oxidation and clinical similarities to fulminant hepatic failure. The following case illustrates our perioperative management of this rarely encountered disorder...

journal_title：Anesthesia and analgesia

authors： Holzman RS,Riley LE,Aron E,Fetherston J

更新日期：2001-05-01 00:00:00

abstract：:The effects of narcotic agents and two inhalation anesthetics on intrabiliary pressure (IBP) were measured before and after morphine (0.2 mg/kg), meperidine (2 mg/kg), fentanyl (0.002 mg/kg), or pentazocine (1 mg/kg) given intramuscularly to guinea pigs, and after halothane (0.5, 1.0, 1.5, or 2.0 MAC) or enflurane (sa...

journal_title：Anesthesia and analgesia

authors： Arguelles JE,Franatovic Y,Romo-Salas F,Aldrete JA

更新日期：1979-03-01 00:00:00

abstract：:The renal effects of pulsatile (pulse pressure 18.0 +/- 1.5 mm Hg [mean +/- SEM]) or nonpulsatile perfusion (mean pulse pressure 1.9 +/- 0.4 mm Hg) during either alpha-stat (mean PaCO2 41.2 +/- 0.9 mm Hg measured at 37 degrees C) or pH-stat (mean PaCO2 60.6 +/- 1.7 mm Hg measured at 37 degrees C) pH management of hypo...

journal_title：Anesthesia and analgesia

authors： Badner NH,Murkin JM,Lok P

更新日期：1992-11-01 00:00:00

abstract：UNLABELLED:In this randomized, double-blinded study we sought to assess the analgesic efficacy of ropivacaine and bupivacaine in combination with sufentanil and the efficacy of ropivacaine alone after major abdominal surgery. Sixty patients undergoing major abdominal surgery received standardized general anesthesia com...

journal_title：Anesthesia and analgesia

authors： Pouzeratte Y,Delay JM,Brunat G,Boccara G,Vergne C,Jaber S,Fabre JM,Colson P,Mann C

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine, a selective α2-adrenergic agonist currently approved for continuous intensive care unit sedation, is being widely evaluated for its role as a potential anesthetic. The closed-loop anesthesia delivery system (CLADS) is a method to automatically administer propofol total intravenous anesthesia...

journal_title：Anesthesia and analgesia

authors： Dutta A,Sethi N,Sood J,Panday BC,Gupta M,Choudhary P,Puri GD

更新日期：2019-07-01 00:00:00

abstract：:The purpose of this study was to examine the effects of alfentanil applied to the surface of the spinal cord and the effects of intravenously administered alfentanil on noxiously evoked activity of dorsal horn neurons. Extracellular single neuron recordings were obtained from wide dynamic range neurons in 26 decerebra...

journal_title：Anesthesia and analgesia

authors： Matsumoto M,Collins JG,Kitahata LM,Yuge O,Tanaka A

更新日期：1986-02-01 00:00:00

abstract：:Direct thrombin inhibitors are heparin alternatives for anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia. We report a case of a large thrombus forming in the venous reservoir while using bivalirudin. We suggest that blood stasis associated with the full venous reservoir m...

journal_title：Anesthesia and analgesia

authors： Wong JK,Tian Y,Shuttleworth P,Caffarelli AD,Reitz BA,Mora-Mangano CT

更新日期：2010-09-01 00:00:00

abstract：:A new mode of pulmonary ventilation called intratracheal pulmonary ventilation (ITPV) was studied. Briefly, a continuous flow of air/oxygen is introduced through a small catheter, the tip of which is positioned at the carina, with a diffuser mounted at its distal end. A timed expiration valve, when closed, provides fo...

journal_title：Anesthesia and analgesia

authors： Kolobow T,Powers T,Mandava S,Aprigliano M,Kawaguchi A,Tsuno K,Mueller E

更新日期：1994-03-01 00:00:00

abstract：UNLABELLED:This report describes treatment with cervical epidural blood patch of low cerebrospinal fluid (CSF) pressure headache resulting from spontaneous CSF leak via a tear in a cervical dural cuff. The leak was diagnosed by a dynamic computed tomography (CT)-myelography study followed by gadolinium enhanced magneti...

journal_title：Anesthesia and analgesia

authors： Cousins MJ,Brazier D,Cook R

更新日期：2004-06-01 00:00:00

abstract：:Several studies have investigated differential block during spinal anesthesia using transcutaneous electrical stimulation (TES) applied to patient's skin. These TES stimuli are claimed to be a surrogate for surgical stimulation, but TES has never been shown to be a realistic surrogate for a surgical stimulus during re...

journal_title：Anesthesia and analgesia

authors： Zaidi AS,Russell IF

更新日期：2005-05-01 00:00:00

abstract：IMPLICATIONS:Complications of IV mannitol administration resulting in compartment syndrome may warrant surgical intervention. Compartment syndrome is difficult to diagnose in the anesthetized patient. Infusing mannitol in an observed IV site permits discontinuation of mannitol before complications ensue. Early recognit...

journal_title：Anesthesia and analgesia

authors： Edwards JJ,Samuels D,Fu ES

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Sedation protocols, including the use of sedation scales and regular sedation stops, help to reduce the length of mechanical ventilation and intensive care unit stay. Because clinical assessment of depth of sedation is labor-intensive, performed only intermittently, and interferes with sedation and sleep, pr...

journal_title：Anesthesia and analgesia

authors： Haenggi M,Ypparila-Wolters H,Buerki S,Schlauri R,Korhonen I,Takala J,Jakob SM

更新日期：2009-09-01 00:00:00

abstract：:Ondansetron and droperidol are both effective in the prevention of postoperative nausea and vomiting (PONV). In this randomized, double-blind study, 80 inpatients scheduled for minor gynecologic surgery received either ondansetron 8 mg intravenously (i.v.) or droperidol 2.5 mg i.v. 5 min prior to induction of isoflura...

journal_title：Anesthesia and analgesia

authors： Grond S,Lynch J,Diefenbach C,Altrock K,Lehmann KA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Previous studies show that the potent, prototypical sigma(1)-receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) prevents cell death after oxygen-glucose deprivation (OGD) in primary cortical neuronal cultures. We tested the hypothesis that PPBP protects neurons by a mechanism involving activation ...

journal_title：Anesthesia and analgesia

authors： Yang S,Alkayed NJ,Hurn PD,Kirsch JR

更新日期：2009-03-01 00:00:00

abstract：:Several federal agencies have recently noted that the United States is in the midst of an unprecedented "opioid epidemic," with an increasing number of opioid-related overdoses and deaths. Providers currently face 3 population-level, public health challenges in providing optimal perioperative pain care: (1) the contin...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Kain ZN

更新日期：2017-11-01 00:00:00

abstract：:Sodium nitroprusside-induced cyanide intoxication has been demonstrated in the laboratory animal and has been experienced clinically during induced hypotensive anesthesia. This is a care report of a successful resuscitation of a severe cardiovascular collapse secondary to suspected sodium nitroprusside-induced cyanide...

journal_title：Anesthesia and analgesia

authors： Perschau RA,Modell JH,Bright RW,Shirley PD

更新日期：1977-07-01 00:00:00

abstract：UNLABELLED:The most effective group of drugs for the treatment of severe pain is opioid analgesics. Their use, however, is limited by decreased effects in neuropathic and chronic pain as a result of increased pain and development of tolerance. Gabapentin (GBP) is effective in both experimental models of chronic pain an...

journal_title：Anesthesia and analgesia

authors： Eckhardt K,Ammon S,Hofmann U,Riebe A,Gugeler N,Mikus G

更新日期：2000-07-01 00:00:00