Case report: a thrombus in the venous reservoir while using bivalirudin in a patient with heparin-induced thrombocytopenia undergoing heart transplantation.

Abstract:

:Direct thrombin inhibitors are heparin alternatives for anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia. We report a case of a large thrombus forming in the venous reservoir while using bivalirudin. We suggest that blood stasis associated with the full venous reservoir maintained in this case led to formation of a large thrombus at the top of the venous canister. Furthermore, activated clotting times may not accurately reflect the magnitude of anticoagulation when using direct thrombin inhibitors.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Wong JK,Tian Y,Shuttleworth P,Caffarelli AD,Reitz BA,Mora-Mangano CT

doi

10.1213/ANE.0b013e3181e9ead3

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

609-12

issue

3

eissn

0003-2999

issn

1526-7598

pii

ANE.0b013e3181e9ead3

journal_volume

111

pub_type

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