A weak negative inotropic effect of protamine sulfate upon the isolated canine heart muscle.

abstract：UNLABELLED:Thiamylal, a chiral thiobarbiturate, is marketed as a racemic product. We studied the serum protein binding and microsomal metabolism of thiamylal enantiomers in vitro. The unbound fraction of R(+)-thiamylal was greater than that of S(-)-thiamylal. The analysis of binding data revealed that both enantiomers ...

journal_title：Anesthesia and analgesia

authors： Sueyasu M,Fujito K,Shuto H,Mizokoshi T,Kataoka Y,Oishi R

更新日期：2000-09-01 00:00:00

abstract：:To determine whether nalbuphine might replace fentanyl as the principal opioid for anesthesia during coronary artery bypass surgery, 20 patients undergoing myocardial revascularization were anesthetized with flunitrazepam and with a continuous infusion of either nalbuphine (an opioid agonist-antagonist) or fentanyl (a...

journal_title：Anesthesia and analgesia

authors： Weiss BM,Schmid ER,Gattiker RI

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Modifications in physician billing patterns have been shown to occur in response to payer incentives, but the phenomenon remains largely unexplored in billing for anesthesia services. Within the field of anesthesiology, Medicare's policy not to provide additional reimbursement for higher ASA physical status ...

journal_title：Anesthesia and analgesia

authors： Schonberger RB,Dutton RP,Dai F

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Safe and effective alternatives are required in labor when epidural analgesia is not appropriate. We hypothesized that patient-controlled IV remifentanil labor analgesia would not be inferior to patient-controlled epidural labor analgesia. METHODS:This randomized nonblinded controlled noninferiority study i...

journal_title：Anesthesia and analgesia

authors： Stocki D,Matot I,Einav S,Eventov-Friedman S,Ginosar Y,Weiniger CF

更新日期：2014-03-01 00:00:00

abstract：:Large doses of morphine sulfate have been reported to cause myocardial lactate production and reduction in coronary blood flow in animals. Similar effects with clinical doses in man would significantly alter the management of cardiac patients. Eleven adult patients with significant coronary arterial disease and normal...

journal_title：Anesthesia and analgesia

authors： Sethna DH,Moffitt EA,Gray RJ,Bussell J,Raymond M,Conklin C,Shell WE,Matloff JM

更新日期：1982-02-01 00:00:00

abstract：:Preoperative anxiety may increase gastric fluid acidity and volume. To pursue this possibility we evaluated the relationship between peroral premedication, preoperative anxiety, and gastric content in 246 consecutive patients presenting for elective gynecologic surgery. All patients fasted overnight and received eithe...

journal_title：Anesthesia and analgesia

authors： Haavik PE,Søreide E,Hofstad B,Steen PA

更新日期：1992-07-01 00:00:00

abstract：:After it was learned that electroanesthesia (EA) could not be produced in a Rhesus monkey which had undergone a circumferential scalp block with 0.25% lidocaine, it was postulated that EA could be produced by electrostimulation of the sensory nerves of the scalp in the rhesus. The work reported here verifies that EA c...

journal_title：Anesthesia and analgesia

authors： Kano T,Cowan GS,Smith RH

更新日期：1976-07-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：UNLABELLED:We examined the effect of ulinastatin, a protease inhibitor purified from human urine, on neuromuscular block caused by vecuronium. Sixty adult patients were randomly divided into four groups of 15 patients each: ulinastatin-posttetanic count (U-PTC), ulinastatin-train-of-four (U-TOF), control-posttetanic co...

journal_title：Anesthesia and analgesia

authors： Saitoh Y,Fujii Y,Oshima T

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:The proportion of live births by cesarean delivery (CD) in China is significant, with some, particularly rural, provinces reporting up to 62.5%. The No Pain Labor & Delivery-Global Health Initiative (NPLD-GHI) was established to improve obstetric and neonatal outcomes in China, including through a reduction ...

journal_title：Anesthesia and analgesia

authors： Drzymalski DM,Guo JC,Qi XQ,Tsen LC,Sun Y,Ouanes JP,Xia Y,Gao WD,Ruthazer R,Hu F,Hu LQ

更新日期：2020-04-22 00:00:00

abstract：:The development of a technique for studying spinal dorsal horn electrophysiology in intact, awake, drug-free cats enables the study of spinal sites and mechanisms of action of anesthetic and analgesic agents in a system that more closely reflects normal physiology. Using this technique, we reevaluated the effect of ke...

journal_title：Anesthesia and analgesia

authors： Collins JG

更新日期：1986-11-01 00:00:00

abstract：UNLABELLED:Adjuncts to local anesthetics for peripheral plexus blockade may enhance the quality and duration of anesthesia and postoperative analgesia. The analgesic, tramadol, has a unique mechanism of action that suggests efficacy as such an adjunct. It displays a central analgesic and peripheral local anesthetic eff...

journal_title：Anesthesia and analgesia

authors： Robaux S,Blunt C,Viel E,Cuvillon P,Nouguier P,Dautel G,Boileau S,Girard F,Bouaziz H

更新日期：2004-04-01 00:00:00

abstract：:We assessed the effect of small clonidine doses on anxiolysis, analgesia, and hemodynamic stability in patients undergoing abdominal hysterectomy. A total of 61 patients, ASA status I-II, were randomly assigned to receive either oral clonidine 100 microg (n = 29) or placebo (n = 32) before surgery and 24 h after surge...

journal_title：Anesthesia and analgesia

authors： Hidalgo MP,Auzani JA,Rumpel LC,Moreira NL Jr,Cursino AW,Caumo W

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:For emergent procedures, in-house teams are required for immediate patient care. However, for many procedures, there is time to bring in a call team from home without increasing patient morbidity. Anesthesia providers taking subspecialty or backup call from home are required to return to the hospital within ...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,Diez C,Potnuru P

更新日期：2019-11-01 00:00:00

abstract：:Colloids and crystalloids are usually administered as treatment for hypovolemia in severely injured patients. However, dilution of clotting factors and platelets together with impaired fibrinogen polymerization are associated with fluid therapy and may aggravate hemorrhage, thus worsening final outcome of these patien...

journal_title：Anesthesia and analgesia

authors： Fries D,Innerhofer P,Reif C,Streif W,Klingler A,Schobersberger W,Velik-Salchner C,Friesenecker B

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Computerized reviews of patient data promise to improve patient care through early and accurate identification of at-risk and well patients. The significance of sampling strategy for patient vital signs data is not known. In the instance of the surgical Apgar score (SAS), we hypothesized that larger sampling...

journal_title：Anesthesia and analgesia

authors： Hyder JA,Kor DJ,Cima RR,Subramanian A

更新日期：2013-12-01 00:00:00

abstract：UNLABELLED:Endotracheal administration of epinephrine 0.02 mg/kg (twice the IV dose) is recommended when IV access is unavailable during cardiopulmonary resuscitation. The standard IV dose has been considered too small for the endotracheal route by causing a detrimental decrease of arterial blood pressure (BP), presuma...

journal_title：Anesthesia and analgesia

authors： Manisterski Y,Vaknin Z,Ben-Abraham R,Efrati O,Lotan D,Berkovitch M,Barak A,Barzilay Z,Paret G

更新日期：2002-10-01 00:00:00

abstract：:Either epidural analgesia or femoral nerve blockade improves analgesia and rehabilitation after total knee arthroplasty. No study has evaluated the combination of femoral nerve blockade and epidural analgesia. In this prospective, randomized, blinded study we investigated combining femoral nerve blockade with epidural...

journal_title：Anesthesia and analgesia

authors： YaDeau JT,Cahill JB,Zawadsky MW,Sharrock NE,Bottner F,Morelli CM,Kahn RL,Sculco TP

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Drug-induced sleep endoscopy (DISE) uses sedative-hypnotics to induce moderate obstruction in sleep apnea patients, thereby facilitating anatomic assessment of obstructive physiology. Implementation of DISE with propofol requires a dosing strategy that reliably and efficiently produces obstruction while mini...

journal_title：Anesthesia and analgesia

authors： Atkins JH,Mandel JE,Rosanova G

更新日期：2014-10-01 00:00:00

abstract：:The dorsal raphe (DR) nucleus is a system of nuclei in the midline of the lower brainstem, which is considered one of the most important nuclei in the modulation of pain in the central nervous system. Central noradrenergic systems play an important role in the control of cardiovascular regulation and pain transmission...

journal_title：Anesthesia and analgesia

authors： Alojado ME,Ohta Y,Kemmotsu O

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Hypotension compromises local tissue perfusion, thereby reducing tissue oxygenation. Hypotension might thus be expected to promote infection. Hypotension on surgical wards, while usually less severe than intraoperative hypotension, is common and often prolonged. In this retrospective cohort study, we tested ...

journal_title：Anesthesia and analgesia

authors： Yilmaz HO,Babazade R,Leung S,Zimmerman NM,Makarova N,Saasouh W,Stocchi L,Gorgun E,Sessler DI,Turan A

更新日期：2018-11-01 00:00:00

abstract：UNLABELLED:Surgery causes changes in hemostasis, leading to a hypercoagulable state that has been linked to both arterial and venous thrombotic complications. The etiology of this state is unknown, but many investigators have hypothesized that perioperative neuroendocrine changes are responsible. We have previously dem...

journal_title：Anesthesia and analgesia

authors： Rosenfeld BA,Nguyen ND,Sung I,Faraday N

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Surveys suggest that, consistent with a high smoking prevalence, Chinese smokers in the general population report little interest in quitting. In other cultures, surgery is a powerful teachable moment for smoking cessation, increasing the rate of spontaneous quitting. We determined the perioperative tobacco ...

journal_title：Anesthesia and analgesia

authors： Yu C,Shi Y,Kadimpati S,Sheng Y,Jing J,Schroeder D,Luo A,Warner DO

更新日期：2013-06-01 00:00:00

abstract：IMPLICATIONS:Carney's complex is characterized by cardiac myxomas, adrenocortical disease, growth hormone-secreting adenomas, and other types of tumors. Its prevalence and incidence are unknown. The anesthesiologist must examine the patient or order tests to exclude cardiac tumors, signs of excess cortisol secretion, a...

journal_title：Anesthesia and analgesia

authors： Szokol JW,Franklin M,Murphy GS,Wynnychenko TM,Sener SF

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:There are three basic types of decision aids to facilitate operating room (OR) management decision-making on the day of surgery. Decision makers can rely on passive status displays (e.g., big screens or whiteboards), active status displays (e.g., text pager notification), and/or command displays (e.g., text ...

journal_title：Anesthesia and analgesia

authors： Dexter F,Willemsen-Dunlap A,Lee JD

更新日期：2007-08-01 00:00:00

abstract：UNLABELLED:Clinical and basic science studies suggest that spinal alpha-2-adrenergic receptor agonists and local anesthetics produce analgesia, but interaction between alpha-2-adrenergic receptor agonists and local anesthetics in the persistent pain model has not been examined. In the present study, using isobolographi...

journal_title：Anesthesia and analgesia

authors： Hao S,Takahata O,Iwasaki H

更新日期：2001-03-01 00:00:00

abstract：:A double-blind comparison of 1.1% lidocaine carbonate and 1.0% lidocaine hydrochloride was carried out in 30 healthy adult patients undergoing upper-extremity surgery under interscalene brachial plexus block. Epinephrine (1:200,000) was added to both solutions just before injection. As compared to lidocaine hydrochlor...

journal_title：Anesthesia and analgesia

authors： Sukhani R,Winnie AP

更新日期：1987-12-01 00:00:00

abstract：:In view of the overall experience regarding regional anesthetic techniques to control postoperative pain in infants and children, it is feasible that a similar efficacy and safety profile can be obtained when using such techniques after major orthopedic procedures such as anterior or posterior spinal fusion. I reviewe...

journal_title：Anesthesia and analgesia

authors： Tobias JD

更新日期：2004-04-01 00:00:00

abstract：UNLABELLED:Propofol (Diprivan(TM); AstraZeneca, Wilmington, DE) is a commonly used drug for the induction of general anesthesia in the ambulatory setting. With the availability of a new bisulfite-containing generic formulation of propofol, questions have arisen regarding its cost effectiveness and safety compared with ...

journal_title：Anesthesia and analgesia

authors： Shao X,Li H,White PF,Klein KW,Kulstad C,Owens A

更新日期：2000-10-01 00:00:00

abstract：:We compared the effect of the lithotomy position on the systolic blood pressure (SBP) with the horizontal position after spinal block. The lithotomy position was performed 5 min after spinal block. The change in SBP was expressed as percent of depression from the baseline value. The SBP increased by the lithotomy posi...

journal_title：Anesthesia and analgesia

authors： Miyabe M,Sonoda H,Namiki A

更新日期：1995-07-01 00:00:00