Sequential use of midazolam and propofol for long-term sedation in postoperative mechanically ventilated patients.

abstract：BACKGROUND:Tumor necrosis factor alpha (TNF-alpha) could trigger p38 mitogen-activated protein kinase (MAPK) activation. Conversely phosphorylated p38 (p-p38) could induce the upregulation of TNF-alpha. In this study, we examined the hypothesis that chronic constrictive injury (CCI) of the sciatic nerve could promote s...

journal_title：Anesthesia and analgesia

authors： Xu L,Huang Y,Yu X,Yue J,Yang N,Zuo P

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The Perioperative Surgical Home (PSH) seeks to remedy the currently highly fragmented and expensive perioperative care in the United States. The 2 specific aims of this health services research study were to assess the association between the preoperative and postoperative elements of an initial PSH model an...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Barman J,Hunter JM Jr,Jones KA,Pittet JF

更新日期：2017-05-01 00:00:00

abstract：:The ex utero intrapartum treatment (EXIT) procedure provides time to secure the airway of the fetus while utero-placental circulation supplies the fetus with oxygen. We report the anesthetic management of a fetus with a large neck mass during an EXIT procedure in which the confirmation of correct endotracheal intubati...

journal_title：Anesthesia and analgesia

authors： Eschertzhuber S,Keller C,Mitterschiffthaler G,Jochberger S,Kühbacher G

更新日期：2005-09-01 00:00:00

abstract：:We designed a randomized, double-blind study to assess the analgesic efficacy and safety of perioperative ketorolac infusion in 95 patients undergoing cholecystectomy. The ketorolac group (n = 48) received premedication, combined with ketorolac 30 mg intramuscularly (IM), followed by a ketorolac continuous infusion (2...

journal_title：Anesthesia and analgesia

authors： Varrassi G,Panella L,Piroli A,Marinangeli F,Varrassi S,Wolman I,Niv D

更新日期：1994-03-01 00:00:00

abstract：:Twenty-four male patients scheduled for elective pulmonary resection were studied to determine whether continuous insufflation of oxygen to the nonventilated lung would reduce intrapulmonary shunting (Qs/Qt) and arterial oxygen desaturation. Measurements of physiologic variables were made using pulmonary arterial and ...

journal_title：Anesthesia and analgesia

authors： Rees DI,Wansbrough SR

更新日期：1982-06-01 00:00:00

abstract：UNLABELLED:Apparently large plasma volumes derived by indocyanine green (PV-ICG) have been determined in the initial period after induction of anesthesia. We tested the hypothesis that possible overestimation of PV-ICG occurs shortly after anesthetic induction. Anesthesia was induced in 13 patients with fentanyl bolus ...

journal_title：Anesthesia and analgesia

authors： Mi WD,Ishihara H,Sakai T,Matsuki A

更新日期：2003-11-01 00:00:00

abstract：:Tramadol analgesia results from a monoaminergic effect by tramadol itself and an opioid effect of its metabolite (+)-M1 formed by O-demethylation of tramadol by CYP2D6. In this study we sought to determine the impact of (+)-M1 on the analgesic effect of tramadol evaluated by experimental pain models. The effect of an ...

journal_title：Anesthesia and analgesia

authors： Enggaard TP,Poulsen L,Arendt-Nielsen L,Brøsen K,Ossig J,Sindrup SH

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Helium produces preconditioning against myocardial infarction by activating prosurvival signaling, but whether nitric oxide (NO) generated by endothelial NO synthase plays a role in this phenomenon is unknown. We tested the hypothesis that NO mediates helium-induced cardioprotection in vivo. METHODS:Rabbits...

journal_title：Anesthesia and analgesia

authors： Pagel PS,Krolikowski JG,Pratt PF Jr,Shim YH,Amour J,Warltier DC,Weihrauch D

更新日期：2008-09-01 00:00:00

abstract：UNLABELLED:We describe the development and evaluation of a simple slide rule that enables the bedside determination of the infusion rate for a particular target plasma concentration of propofol. The infusion rate to reach this target concentration at time (t) is the product of the target concentration, body weight, and...

journal_title：Anesthesia and analgesia

authors： Bruhn J,Bouillon TW,Röpcke H,Hoeft A

更新日期：2003-01-01 00:00:00

abstract：IMPLICATIONS:This case report shows that atelectasis of the left lung-induced by extrinsic compression of the left main bronchus by an aortic aneurysm and persisting despite aggressive conservative treatment-may be effectively treated by bronchial stenting and high-frequency percussive ventilation. ...

journal_title：Anesthesia and analgesia

authors： Heringlake M,Schumacher J,Sedemund-Adib B,Bahlmann L,Eleftheriadis S,Sievers HH,Dalhoff K,Schmucker P

更新日期：2002-11-01 00:00:00

abstract：:We describe the treatment of two patients with hemorrhagic shock unresponsive to volume replacement and catecholamines. Both patients responded to a small-dose infusion of vasopressin, which allowed tapering off of the catecholamines. The possible role of small-dose infusions of vasopressin in fluid- and catecholamine...

journal_title：Anesthesia and analgesia

authors： Sharma RM,Setlur R

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Different drugs have been used to enhance postoperative neuraxial opioid analgesia and reduce adverse effects. METHODS:We randomized 60 patients into 2 groups to receive either 2 mL saline or 0.1 mg/kg dexamethasone IV before the administration of intrathecal anesthesia (15 mg and meperidine 15 mg). After s...

journal_title：Anesthesia and analgesia

authors： Movafegh A,Soroush AR,Navi A,Sadeghi M,Esfehani F,Akbarian-Tefaghi N

更新日期：2007-04-01 00:00:00

abstract：:The purpose of this study was to evaluate the effects of preemptive and postlesion sympathectomy in the sciatic cryoneurolysis (SCN) model of neuropathic pain in rats. SCN in rats produces a prolonged significant mechanical allodynia (hypersensitivity to previously non-noxious mechanical stimuli) with no thermal hyper...

journal_title：Anesthesia and analgesia

authors： Willenbring S,Beauprie IG,DeLeo JA

更新日期：1995-09-01 00:00:00

abstract：:Two hundred twenty-two spinal anesthesias were administered with 10 mg. of tetracaine and 1 ml. of 10 percent dextrose to investigate the effects of vasopressors, patients age, and pH of cerebrospinal fluid on the onset and duration of spinal anesthesia. Neither the differences in overall age, cerebrospinal fluid pH, ...

journal_title：Anesthesia and analgesia

authors： Park WY,Balingit PE,Macnamara TE

更新日期：1975-07-01 00:00:00

abstract：:We studied the effect of halothane on the fetal cardiovascular system of six lambs in utero by measuring fetal heart rate and femoral arterial blood pressure and by injecting labeled microspheres during a control period and again after 60 and 90 min of halothane anesthesia administered to six pregnant ewes at an inspi...

journal_title：Anesthesia and analgesia

authors： Biehl DR,Tweed WA,Cote J,Wade JG,Sitar D

更新日期：1983-05-01 00:00:00

abstract：:The average duration of hospitalization after total knee arthroplasty (TKA) in the United States is 4-5 days. In this two-phase study we investigated the feasibility of converting TKA into an overnight-stay procedure using a continuous femoral nerve block provided at home through postoperative day 4. Nine of 10 patien...

journal_title：Anesthesia and analgesia

authors： Ilfeld BM,Gearen PF,Enneking FK,Berry LF,Spadoni EH,George SZ,Vandenborne K

更新日期：2006-01-01 00:00:00

abstract：:Preoperative anxiety may increase gastric fluid acidity and volume. To pursue this possibility we evaluated the relationship between peroral premedication, preoperative anxiety, and gastric content in 246 consecutive patients presenting for elective gynecologic surgery. All patients fasted overnight and received eithe...

journal_title：Anesthesia and analgesia

authors： Haavik PE,Søreide E,Hofstad B,Steen PA

更新日期：1992-07-01 00:00:00

abstract：UNLABELLED:Postoperative pain is a common reason for the delayed discharge and unanticipated hospital admission of out-patients. In this study, we examined the pattern of pain in ambulatory surgical patients and determined those factors that predict postoperative pain. Ten thousand eight consecutive ambulatory surgical...

journal_title：Anesthesia and analgesia

authors： Chung F,Ritchie E,Su J

更新日期：1997-10-01 00:00:00

abstract：UNLABELLED:Although acute tolerance to analgesia develops rapidly with remifentanil, it is unknown whether acute tolerance also develops to its nonanalgesic effects. We investigated the analgesic and cardiorespiratory effects of remifentanil during a continuous infusion in a rabbit model. Ten tracheotomized New Zealand...

journal_title：Anesthesia and analgesia

authors： Hayashida M,Fukunaga A,Hanaoka K

更新日期：2003-11-01 00:00:00

abstract：:Local anesthetics have been used clinically for more than a century, but new insights into their mechanisms of action and their interaction with biological systems continue to surprise researchers and clinicians alike. Next to their classic action on voltage-gated sodium channels, local anesthetics interact with calci...

journal_title：Anesthesia and analgesia

authors： Lirk P,Hollmann MW,Strichartz G

更新日期：2018-04-01 00:00:00

abstract：:The effect of isoflurane on regional myocardial metabolism and blood flow, when used as an adjunct to fentanyl-nitrous oxide anesthesia, to control intraoperative hypertension was investigated. Twenty-two patients with two- or three-vessel coronary artery disease with an ejection fraction greater than 0.5 and on beta-...

journal_title：Anesthesia and analgesia

authors： Sahlman L,Milocco I,Appelgren L,William-Olsson G,Ricksten SE

更新日期：1989-02-01 00:00:00

abstract：UNLABELLED:We performed this study to assess the influence of endotracheal tube (ETT) tip design (Murphy-tip versus Magill-tip) on nasal trauma during nasotracheal intubation with a conventional polyvinyl chloride ETT. Patients were randomly allocated to one of four groups (n = 25 each): Magill-tipped ETT and Murphy-ti...

journal_title：Anesthesia and analgesia

authors： Lee JH,Kim CH,Bahk JH,Park KS

更新日期：2005-10-01 00:00:00

abstract：UNLABELLED:Adenosine and adenosine analogs induce analgesia in humans and presumed antinociception in animal models when administered both systemically and intrathecally. In the present investigation in rats, we studied the effects of intrathecally administered adenosine analogs, with or without systemic coadministrati...

journal_title：Anesthesia and analgesia

authors： Sjölund KF,Sollevi A,Segerdahl M,Lundeberg T

更新日期：1997-09-01 00:00:00

abstract：:As of November 2016, the Florida Department of Health (FDH) and the Centers for Disease Control and Prevention have confirmed more than 4000 travel-related Zika virus (ZIKV) infections in the United States with >700 of those in Florida. There have been 139 cases of locally acquired infection, all occurring in Miami, F...

journal_title：Anesthesia and analgesia

authors： Tutiven JL,Pruden BT,Banks JS,Stevenson M,Birnbach DJ

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The etiology of postoperative cognitive decline (POCD) remains to be determined. Anesthetic isoflurane, but not desflurane, may induce neurotoxicity. However, the functional consequences of these effects have not been assessed. We therefore performed a pilot study to determine the effects of isoflurane and d...

journal_title：Anesthesia and analgesia

authors： Zhang B,Tian M,Zhen Y,Yue Y,Sherman J,Zheng H,Li S,Tanzi RE,Marcantonio ER,Xie Z

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Botulinum neurotoxin type A (BoNT/A) has been used as an analgesic for myofascial pain syndromes, migraine, and other types of headaches. Although an antinociceptive effect of central or peripheral administration of BoNT/A is suggested, the effect at the spinal level is still unclear. In this study, we evalu...

journal_title：Anesthesia and analgesia

authors： Lee WH,Shin TJ,Kim HJ,Lee JK,Suh HW,Lee SC,Seo K

更新日期：2011-01-01 00:00:00

abstract：UNLABELLED:Propofol and thiopental have been used clinically in combination for induction of anesthesia. Studies suggest that this mixture has synergistic activity, recovery characteristics similar to propofol alone, and bactericidal effects on multiple organisms. It may therefore be both clinically useful and cost-eff...

journal_title：Anesthesia and analgesia

authors： Lazar ER,Jolly DT,Tam YK,Hrazdil J,Tawfik SR,Clanachan AS

更新日期：1998-02-01 00:00:00

abstract：UNLABELLED:The optimal dose and timing of 5-HT(3) antagonist administration for prophylaxis against postoperative nausea and vomiting (PONV) remains controversial. Although 5-HT(3) antagonists seem to be most effective when administered near the end of surgery, there are no data on the comparative efficacy or costs ass...

journal_title：Anesthesia and analgesia

authors： Zarate E,Watcha MF,White PF,Klein KW,Sa Rego M,Stewart DG

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Tissue factor pathway inhibitor (TFPI) is a 40-kDa, endogenous protein that inhibits tissue factor (TF)-initiated coagulation by bonding with activated factor X (FXa). The TFPI/FXa complex then subsequently binds with TF/activated factor VII (FVIIa) complex, ultimately inhibiting thrombin generation. Heparin...

journal_title：Anesthesia and analgesia

authors： Audu P,Nielsen VG,Armstead V,Powell G,Kim J,Kim L,Mehta M

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Neonates undergoing cardiac surgery are especially prone to the hemostatic alterations of cardiopulmonary bypass (CPB) and are at high risk for post-CPB bleeding. An immature coagulation system, significant hemodilution from the CPB prime, long CPB times at low temperatures, and extensive suture lines increa...

journal_title：Anesthesia and analgesia

authors： Guzzetta NA,Allen NN,Wilson EC,Foster GS,Ehrlich AC,Miller BE

更新日期：2015-02-01 00:00:00