Does preoperative anxiety influence gastric fluid volume and acidity?

Abstract:

:Preoperative anxiety may increase gastric fluid acidity and volume. To pursue this possibility we evaluated the relationship between peroral premedication, preoperative anxiety, and gastric content in 246 consecutive patients presenting for elective gynecologic surgery. All patients fasted overnight and received either flunitrazepam 1 mg, oxazepam 25 mg, or placebo with 20 mL of water on the morning of surgery in a randomized, double-blind fashion. The patients assessed relief of anxiety using a four-graded scale (excellent, good, fair, poor). Both flunitrazepam and oxazepam decreased anxiety (P less than 0.01) compared with placebo. However, no correlations between type of premedication or level of anxiety and gastric contents were found. The proportion of patients with gastric fluid volume greater than 25 mL and pH less than 2.5 was not significantly different in any of the groups studied. These results suggest that neither peroral benzodiazepine premedication nor preoperative anxiety have a clinically important impact on gastric content in patients presenting for elective gynecologic surgery.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Haavik PE,Søreide E,Hofstad B,Steen PA

doi

10.1213/00000539-199207000-00017

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

91-4

issue

1

eissn

0003-2999

issn

1526-7598

journal_volume

75

pub_type

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