Procoagulant activity in hemostasis and thrombosis: Virchow's triad revisited.

abstract：BACKGROUND:Lidocaine is used clinically for tactile allodynia associated with diabetes-induced neuropathy. Although the analgesic effect of lidocaine through suppression of microglial activation has been implicated in the development of injury-induced neuropathic pain, its mechanism of action in diabetes-induced tactil...

journal_title：Anesthesia and analgesia

authors： Suzuki N,Hasegawa-Moriyama M,Takahashi Y,Kamikubo Y,Sakurai T,Inada E

更新日期：2011-10-01 00:00:00

abstract：UNLABELLED:We examined the effects of two perioperative pain management techniques on recovery after laparotomy, as assessed by body weight (BW) and food consumption (FC). All rats received a preoperative intrathecal mixture of morphine plus bupivacaine combined with one of two treatments: (a) injection of slow-release...

journal_title：Anesthesia and analgesia

authors： Shavit Y,Fish G,Wolf G,Mayburd E,Meerson Y,Yirmiya R,Beilin B

更新日期：2005-10-01 00:00:00

abstract：:We used laser-Doppler flowmetry to compare the effects of the volatile anesthetics, isoflurane and halothane, on the cerebrovascular response to CO2 inhalation in male Sprague-Dawley rats. The effects of 0.5 and 1.5 minimum alveolar anesthetic concentrations (MAC) of halothane and isoflurane on the microcirculatory re...

journal_title：Anesthesia and analgesia

authors： Lee JG,Smith JJ,Hudetz AG,Hillard CJ,Bosnjak ZJ,Kampine JP

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Intraoperative hypotension is common and associated with organ injury and death, although randomized data showing a causal relationship remain sparse. A risk-adjusted measure of intraoperative hypotension may therefore contribute to quality improvement efforts. METHODS:The measure we developed defines hypot...

journal_title：Anesthesia and analgesia

authors： Christensen AL,Jacobs E,Maheshwari K,Xing F,Zhao X,Simon SE,Domino KB,Posner KL,Stewart AF,Sanford JA,Sessler DI

更新日期：2020-11-23 00:00:00

abstract：:The suction-biopsy channel of a flexible bronchofiberscope was used to provide subglottic jet ventilation in six dogs and eight adult human subjects. In dogs, after 75 minutes of ventilation at a driving pressure of 2580 torr/cm2 (50 lb/in2) the PaO2 was 412 +/- 18 torr and the PaCO2 32 +/- 3 torr with a peak airway p...

journal_title：Anesthesia and analgesia

authors： Satyanarayana T,Capan L,Ramanathan S,Chalon J,Turndorf H

更新日期：1980-05-01 00:00:00

abstract：UNLABELLED:The purpose of the investigation was to assess the effects of desflurane (DES) on left ventricular heart function during basal barbiturate anesthesia in a closed-pericardium, closed-chest acute swine model. The study was performed in 11 normoventilated adult pigs. Hemodynamic measurements were obtained using...

journal_title：Anesthesia and analgesia

authors： Sundeman H,Haney M,Broomé M,Häggmark S,Johansson G,Winsö O,Biber B

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Cerebral cholinergic transmission plays a key role in cognitive function, and anticholinergic drugs administered during the perioperative phase are a hypothetical cause of postoperative cognitive dysfunction (POCD). We hypothesized that a perioperative increase in serum anticholinergic activity (SAA) is asso...

journal_title：Anesthesia and analgesia

authors： Rossi A,Burkhart C,Dell-Kuster S,Pollock BG,Strebel SP,Monsch AU,Kern C,Steiner LA

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Previous animal and human studies suggested that nicotine might have an antinociceptive effect. We hypothesized that the preoperative application of a 7 mg nicotine patch would result in reduced postoperative analgesic requirements in patients undergoing radical retropubic prostatectomy (RRP) under general a...

journal_title：Anesthesia and analgesia

authors： Habib AS,White WD,El Gasim MA,Saleh G,Polascik TJ,Moul JW,Gan TJ

更新日期：2008-09-01 00:00:00

abstract：UNLABELLED:We designed this study to determine the minimum dose of dexamethasone for preventing nausea and vomiting associated with the use of morphine by patient-controlled analgesia (PCA). Two hundred forty female patients were randomly assigned to receive dexamethasone 2, 4, 8, or 12 mg IV immediately before inducti...

journal_title：Anesthesia and analgesia

authors： Lee Y,Lai HY,Lin PC,Lin YS,Huang SJ,Shyr MH

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Short-term case cancellation causes frustration for anesthesiologists, surgeons, and patients and leads to suboptimal use of operating room (OR) resources. In many facilities, >10% of all cases are cancelled on the day of surgery, thereby causing major problems for OR management and anesthesia departments. T...

journal_title：Anesthesia and analgesia

authors： Schuster M,Neumann C,Neumann K,Braun J,Geldner G,Martin J,Spies C,Bauer M,CASCAES Study Group.

更新日期：2011-09-01 00:00:00

abstract：:Prostaglandin E(2) receptors, subtype EP(1) (PGE(2)EP(1)) have been linked to several physiologic responses, such as fever, inflammation, and mechanical hyperalgesia. Local anesthetics modulate these responses, which may be due to direct interaction of local anesthetics with PGE(2)EP(1) receptor signaling. We sought t...

journal_title：Anesthesia and analgesia

authors： Hönemann CW,Heyse TJ,Möllhoff T,Hahnenkamp K,Berning S,Hinder F,Linck B,Schmitz W,van Aken H

更新日期：2001-09-01 00:00:00

abstract：:Vecuronium (Org NC 45) was used in 27 parturients undergoing elective cesarean section under general anesthesia. One of the parturients had a twin pregnancy. Neuromuscular transmission was assessed clinically by stimulating the ulnar nerve and observing the contraction of the fingers. An initial bolus of 0.05 mg . kg-...

journal_title：Anesthesia and analgesia

authors： Baraka A,Noueihed R,Sinno H,Wakid N,Agoston S

更新日期：1983-10-01 00:00:00

abstract：:The effect of the alpha 2-agonist dexmedetomidine on the cerebral blood flow (CBF) and the metabolic rate for oxygen was studied by a sagittal sinus outflow technique in dogs during halothane anesthesia. Dexmedetomidine was given in a dose (10 micrograms/kg) reported to reduce the anesthetic requirement of halothane b...

journal_title：Anesthesia and analgesia

authors： Karlsson BR,Forsman M,Roald OK,Heier MS,Steen PA

更新日期：1990-08-01 00:00:00

abstract：UNLABELLED:We designed this study to assess the efficacy of dolasetron compared with clonidine and placebo in prophylaxis of postanesthetic shivering. We included 90 patients undergoing elective abdominal or urologic surgery. The patients were randomly assigned to one three groups (each group n = 30) using a double-bli...

journal_title：Anesthesia and analgesia

authors： Piper SN,Röhm KD,Maleck WH,Fent MT,Suttner SW,Boldt J

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:There are profound racial and ethnic disparities in obstetric outcomes in the United States, but little is known about disparities in risk of postpartum hemorrhage (PPH). We explored the association of race and ethnicity on the risk of PPH due to uterine atony with sequential adjustment for possible mediatin...

journal_title：Anesthesia and analgesia

authors： Bryant A,Mhyre JM,Leffert LR,Hoban RA,Yakoob MY,Bateman BT

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Goal-directed fluid therapy (GDFT) is associated with improved outcomes after surgery. The esophageal Doppler monitor (EDM) is widely used, but has several limitations. The NICOM, a completely noninvasive cardiac output monitor (Cheetah Medical), may be appropriate for guiding GDFT. No prospective studies ha...

journal_title：Anesthesia and analgesia

authors： Waldron NH,Miller TE,Thacker JK,Manchester AK,White WD,Nardiello J,Elgasim MA,Moon RE,Gan TJ

更新日期：2014-05-01 00:00:00

abstract：:Rifampin is commonly used for the treatment of tuberculosis and staphylococcal infections, as well as for prevention of infection in cardiac valve and bone surgeries. We report a case of profound hypotension after anesthesia induction with propofol in a patient who was treated with two 600 mg doses of rifampin for pro...

journal_title：Anesthesia and analgesia

authors： Mirzakhani H,Nozari A,Ehrenfeld JM,Peterfreund R,Szabo M,Walsh JL,Jiang Y,Sandberg W,Rosow C,Wang J

更新日期：2013-07-01 00:00:00

abstract：UNLABELLED:The last decade has witnessed a proliferation of devices or methods that facilitate intubation in difficult circumstances, maintain ventilation, or which do both. These all require properly functioning and specially designed apparatus, the use of which requires variable degrees of expertise. This technical c...

journal_title：Anesthesia and analgesia

authors： Beattie C

更新日期：2002-02-01 00:00:00

abstract：UNLABELLED:We present the case of a 57-yr-old patient who suffered an unexplained cerebrovascular event 3 days after being struck by a motor vehicle. Workup demonstrated a previously unknown patient foramen ovale. The etiologies of paradoxical embolism in trauma are discussed. IMPLICATIONS:Paradoxical embolism after m...

journal_title：Anesthesia and analgesia

authors： Price MD,Kanake P,Talmor D

更新日期：2004-04-01 00:00:00

abstract：UNLABELLED:To determine whether a weight-related dose had advantages over a fixed, large-dose regimen, we measured plasma concentrations of aprotinin by using an enzyme-linked immunosorbent assay method at set time points in 30 patients having heart surgery with cardiopulmonary bypass. A weight-related dose comprising ...

journal_title：Anesthesia and analgesia

authors： Royston D,Cardigan R,Gippner-Steppert C,Jochum M

更新日期：2001-04-01 00:00:00

abstract：IMPLICATIONS:The number of patients supported by ventricular assist devices (VADs) that present for noncardiac surgery is increasing in our institution. Our recent experience with eight such patients is reported, along with a review of the most commonly implanted VADs and the anesthetic implications and considerations ...

journal_title：Anesthesia and analgesia

authors： Stone ME,Soong W,Krol M,Reich DL

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:The perioperative course of patients undergoing intracranial surgery is frequently complicated by hypertensive episodes. Dexmedetomidine (DEX), an alpha-2 adrenoreceptor agonist, is gaining popularity in neuroanesthesia, because its sympatholytic and antinociceptive properties may improve hemodynamic stabili...

journal_title：Anesthesia and analgesia

authors： Bekker A,Sturaitis M,Bloom M,Moric M,Golfinos J,Parker E,Babu R,Pitti A

更新日期：2008-10-01 00:00:00

abstract：:We studied the effect of halothane on the fetal cardiovascular system of six lambs in utero by measuring fetal heart rate and femoral arterial blood pressure and by injecting labeled microspheres during a control period and again after 60 and 90 min of halothane anesthesia administered to six pregnant ewes at an inspi...

journal_title：Anesthesia and analgesia

authors： Biehl DR,Tweed WA,Cote J,Wade JG,Sitar D

更新日期：1983-05-01 00:00:00

abstract：:Ondansetron is a potent antiemetic drug that acts through inhibition of the 5HT3 receptors for serotonin. Minimum alveolar concentration (MAC) for isoflurane is not affected by systemic ondansetron; however ondansetron is a substrate of P-glycoprotein, a transport pump expressed in the blood-brain barrier. Thus, we hy...

journal_title：Anesthesia and analgesia

authors： Scott JA,Wood M,Flood P

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Statins have been shown to possess antiinflammatory and immunomodulatory effects. In this study, we sought to determine if preoperative statin therapy is associated with a reduced frequency of postoperative acute respiratory distress syndrome (ARDS) in surgical populations at increased risk of developing ARD...

journal_title：Anesthesia and analgesia

authors： Yadav H,Lingineni RK,Slivinski EJ,Stockler KA,Subramanian A,Oderich GS,Wigle DA,Carter RE,Kor DJ

更新日期：2014-10-01 00:00:00

abstract：:Wound perfusion and oxygenation are important determinants of the development of postoperative wound infections. Supplemental fluid administration significantly increases tissue oxygenation in surrogate wounds in the subcutaneous tissue of the upper arm in perioperative surgical patients. We tested the hypothesis that...

journal_title：Anesthesia and analgesia

authors： Kabon B,Akça O,Taguchi A,Nagele A,Jebadurai R,Arkilic CF,Sharma N,Ahluwalia A,Galandiuk S,Fleshman J,Sessler DI,Kurz A

更新日期：2005-11-01 00:00:00

abstract：:Although the pathogenesis of acute renal injury after cardiac surgery is multifactorial, atherosclerosis of the ascending aorta and embolic burden are strong independent predictors. Use of the Symmetry aortic connector device (ACD) for proximal anastomosis of coronary grafts may reduce ascending aortic atheroembolism....

journal_title：Anesthesia and analgesia

authors： Fischer SS,Phillips-Bute B,Swaminathan M,Milano C,Stafford-Smith M

更新日期：2006-01-01 00:00:00

abstract：UNLABELLED:Endotracheal administration of epinephrine 0.02 mg/kg (twice the IV dose) is recommended when IV access is unavailable during cardiopulmonary resuscitation. The standard IV dose has been considered too small for the endotracheal route by causing a detrimental decrease of arterial blood pressure (BP), presuma...

journal_title：Anesthesia and analgesia

authors： Manisterski Y,Vaknin Z,Ben-Abraham R,Efrati O,Lotan D,Berkovitch M,Barak A,Barzilay Z,Paret G

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Atelectasis occurs regularly after induction of general anesthesia, persists postoperatively, and may contribute to significant postoperative morbidity and additional health care costs. Laparoscopic surgery has been reported to be associated with an increased incidence of postoperative atelectasis. It has be...

journal_title：Anesthesia and analgesia

authors： Talab HF,Zabani IA,Abdelrahman HS,Bukhari WL,Mamoun I,Ashour MA,Sadeq BB,El Sayed SI

更新日期：2009-11-01 00:00:00

abstract：IMPLICATIONS:Postoperative management of sedation and analgesia in pediatric cardiac patients presents many challenges. This case report describes a child who experienced dramatic clinical improvement with the postoperative use of caudal morphine and clonidine after conventional therapy had failed. ...

journal_title：Anesthesia and analgesia

authors： Diaz LK,Cantu F

更新日期：2003-01-01 00:00:00