Reversal of combination nondepolarized neuromuscular block.

Abstract:

:The antagonism of a pancuronium-curare (P + C) neuromuscular block was assessed and compared to the antagonism of a pancuronium (P) block. One group of seven patients received P + C (0.024 mg/kg + 0.144 mg/kg); another similar group of seven patients received P (0.07 mg/kg). Both groups were anesthetized with nitrous oxide/oxygen/narcotic anesthesia. Each patient received 0.025 mg/kg of neostigmine when a train-of-four revealed only one twitch (90% block). The resultant antagonism of the pancuronium-curare blocks was the same as the antagonism of the pancuronium blocks (train-of-four ratio, 0.38 vs 0.32; P = 0.5). The authors conclude that neostigmine requirements for combination blocks are the same as those for single agent blocks.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Vitez TS,Difrancesco LV

subject

Has Abstract

pub_date

1983-12-01 00:00:00

pages

1081-2

issue

12

eissn

0003-2999

issn

1526-7598

journal_volume

62

pub_type

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