Meloxicam, a specific COX-2 inhibitor, does not enhance the isoflurane minimum alveolar concentration reduction produced by morphine in the rat.

abstract：UNLABELLED:Linking physiological pharmacokinetic models to models of the cardiovascular system requires knowledge of the sites in the body that mediate a drug's cardiovascular effects. We examined the role of the coronary concentrations of propofol. Nine sheep anesthetized with isoflurane (2%) were instrumented acutely...

journal_title：Anesthesia and analgesia

authors： Zheng D,Upton RN,Martinez AM

更新日期：2003-06-01 00:00:00

abstract：:Blind oral intubation using the Augustine Guide is helpful for intubating the trachea of patients presenting with difficult airways. This device has been modified by adding a fiberoptic scope with a built-in battery-powered light. We studied this Augustine Scope in 104 patients (Group AS) and compared the results with...

journal_title：Anesthesia and analgesia

authors： Krafft P,Krenn CG,Fitzgerald RD,Pernerstorfer T,Fridrich P,Weinstabl C

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Burnout is a psychological syndrome that results from chronic exposure to job stress. It is defined by a triad of emotional exhaustion, depersonalization, and reduced personal accomplishment. In research, mostly from high-income countries, burnout is common in health care professionals, especially in anesthe...

journal_title：Anesthesia and analgesia

authors： Mumbwe MC,McIsaac D,Jarman A,Bould MD

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Tissue factor pathway inhibitor (TFPI) is a 40-kDa, endogenous protein that inhibits tissue factor (TF)-initiated coagulation by bonding with activated factor X (FXa). The TFPI/FXa complex then subsequently binds with TF/activated factor VII (FVIIa) complex, ultimately inhibiting thrombin generation. Heparin...

journal_title：Anesthesia and analgesia

authors： Audu P,Nielsen VG,Armstead V,Powell G,Kim J,Kim L,Mehta M

更新日期：2006-10-01 00:00:00

abstract：:Because we have noticed dramatic hemodynamic responses in brain dead patients undergoing surgery for organ donation, we analyzed the anesthetic records of cadaver organ donors. Ten records contain complete data for heart rate, blood pressure, central venous pressure, and time of incision. Systolic pressure increased b...

journal_title：Anesthesia and analgesia

authors： Wetzel RC,Setzer N,Stiff JL,Rogers MC

更新日期：1985-02-01 00:00:00

abstract：:Combinations of benzodiazepines (midazolam and diazepam) with barbiturates (pentobarbital and phenobarbital) exhibit synergistic (supra-additive) hypnotic interactions in rats. Because both benzodiazepines and barbiturates interact with the gamma-aminobutyric acidA (GABAA) receptor complex, we have tested the hypothes...

journal_title：Anesthesia and analgesia

authors： DeLorey TM,Kissin I,Brown P,Brown GB

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Chronic pain is one of the most common complaints in patients with human immunodeficiency virus (HIV)-associated sensory neuropathy. Ryanodine receptor (RyR) and mitochondrial oxidative stress are involved in neuropathic pain induced by nerve injury. Here, we investigated the role of RyR and mitochondrial su...

journal_title：Anesthesia and analgesia

authors： Godai K,Takahashi K,Kashiwagi Y,Liu CH,Yi H,Liu S,Dong C,Lubarsky DA,Hao S

更新日期：2019-07-01 00:00:00

abstract：UNLABELLED:A microscope will be used for the first case of the day in operating room (OR) 1 and then may be used in the second case of the day by a different surgeon in a different OR, OR 2. Provided that the probability is reasonably high that the first case of the day in OR 2 will last longer than the first case in O...

journal_title：Anesthesia and analgesia

authors： Dexter F,Traub RD

更新日期：2000-04-01 00:00:00

abstract：:Atelectasis is common after cardiac surgery and may result in impaired gas exchange. Continuous positive airway pressure (CPAP) is often used to prevent or treat postoperative atelectasis. We hypothesized that noninvasive pressure support ventilation (NIPSV) by increasing tidal volume could improve the evolution of at...

journal_title：Anesthesia and analgesia

authors： Pasquina P,Merlani P,Granier JM,Ricou B

更新日期：2004-10-01 00:00:00

abstract：:Outpatients undergoing minor diagnostic and therapeutic procedures associated with intermittent discomfort are frequently given bolus injections of intravenous opioid analgesics. In a group of 80 healthy women undergoing vaginal ovum pickup procedures, we evaluated patient-controlled administration of alfentanil using...

journal_title：Anesthesia and analgesia

authors： Zelcer J,White PF,Chester S,Paull JD,Molnar R

更新日期：1992-07-01 00:00:00

abstract：:The purpose of this study was to determine the analgesic efficacy, opioid-sparing effect, and tolerability of ketorolac administered as an intravenous (i.v.) bolus followed by a continuous infusion after total hip or knee arthroplasty. After general anesthesia, patients received either placebo or ketorolac 30 mg i.v. ...

journal_title：Anesthesia and analgesia

authors： Etches RC,Warriner CB,Badner N,Buckley DN,Beattie WS,Chan VW,Parsons D,Girard M

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:The spinal cord is an important site where volatile anesthetics decrease sensation and produce immobility. Beyond this knowledge, our understanding of a site of anesthetic action is limited. Previous evidence suggests that dorsal horn neurons with ascending projections may be more susceptible to depression b...

journal_title：Anesthesia and analgesia

authors： Barter LS,Mark LO,Jinks SL,Carstens EE,Antognini JF

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Peripheral neuropathy is a common dose-limiting side effect of chemotherapy. There are no clinically proven analgesics for the treatment of this condition. Drugs from different classes have been tested with mixed results. Identification of novel molecular targets for analgesic(s) is important. Antagonism of ...

journal_title：Anesthesia and analgesia

authors： Wala EP,Crooks PA,McIntosh JM,Holtman JR Jr

更新日期：2012-09-01 00:00:00

abstract：:Jet ventilation is often used during laryngoscopy to permit improved visualization of the larynx and to eliminate a potentially flammable endotracheal tube when laser surgery of the airway is performed. Observation of chest wall movement and blood gas analysis are the usual standards for assessing the adequacy of vent...

journal_title：Anesthesia and analgesia

authors： Gottschalk A,Mirza N,Weinstein GS,Edwards MW

更新日期：1997-07-01 00:00:00

abstract：UNLABELLED:We investigated the physiological reaction to mobilization the first and second day after aortic valve replacement in an open, prospective study. Hemodynamic and oxygenation variables were recorded in 15 patients using a pulmonary artery oximetry catheter and bench oximetry. Serious intraoperative events occ...

journal_title：Anesthesia and analgesia

authors： Kirkeby-Garstad I,Sellevold OF,Stenseth R,Skogvoll E,Karevold A

更新日期：2004-02-01 00:00:00

abstract：UNLABELLED:Forty-eight healthy parturients scheduled for elective cesarean delivery were randomly allocated to receive intrathecally either 12 mg of hyperbaric bupivacaine plus 12.5 microg of fentanyl (n = 23) or bupivacaine alone (n = 25). In the latter group, IV 12.5 microg of fentanyl was administered immediately af...

journal_title：Anesthesia and analgesia

authors： Siddik-Sayyid SM,Aouad MT,Jalbout MI,Zalaket MI,Berzina CE,Baraka AS

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Thoracic aorta dissection is an acute critical condition associated with shock-induced endotheliopathy, coagulopathy, massive bleeding, and significant morbidity and mortality. Our aim was to compare the effect of coagulation support with solvent/detergent-treated pooled plasma (OctaplasLG) versus standard f...

journal_title：Anesthesia and analgesia

authors： Stensballe J,Ulrich AG,Nilsson JC,Henriksen HH,Olsen PS,Ostrowski SR,Johansson PI

更新日期：2018-10-01 00:00:00

abstract：:This study examined global hemodynamic responses to increasing concentrations of halothane and isoflurane in pigs with an acute critical coronary stenosis (CCS) on the left anterior descending coronary artery (LAD). The CCS was caused by graded inflation of an hydraulic occluder to the point where no hyperemic respons...

journal_title：Anesthesia and analgesia

authors： Gilbert M,Mori M,Myhre ES

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Even though current perception threshold (CPT) has been used for evaluating the effectiveness of sensory block in patients before surgery, its reliability under controlled conditions has not been investigated. Two independent investigations were performed. The primary objective of the first study was to dete...

journal_title：Anesthesia and analgesia

authors： Gaudreault F,Drolet P,Fallaha M,Varin F

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Pulmonary complications related to residual neuromuscular blockade lead to morbidity and mortality. Using an interrupted time series design, we tested whether proportions of reintubation for respiratory failure or new noninvasive ventilation were changed after a system-wide transition of the standard reversa...

journal_title：Anesthesia and analgesia

authors： Krause M,McWilliams SK,Bullard KJ,Mayes LM,Jameson LC,Mikulich-Gilbertson SK,Fernandez-Bustamante A,Bartels K

更新日期：2020-07-01 00:00:00

abstract：UNLABELLED:In the present study, we investigated the effect of remifentanil on cerebral blood flow velocity (CBFV). We investigated 20 patients (ASA physical status III) scheduled for elective coronary artery bypass graft surgery. Anesthesia was induced with remifentanil 5 microg/kg IV (Group 1, n = 10) or 2 microg/kg ...

journal_title：Anesthesia and analgesia

authors： Paris A,Scholz J,von Knobelsdorff G,Tonner PH,Schulte am Esch J

更新日期：1998-09-01 00:00:00

abstract：UNLABELLED:We sought to determine minimum alveolar anesthetic concentrations for skin incision (MAC) and for tracheal extubation (MAC(Ex)) for sevoflurane and its associated awakening time and respiratory complications during emergence from sevoflurane anesthesia in children. We studied 40 (20 in each group) unpremedic...

journal_title：Anesthesia and analgesia

authors： Inomata S,Suwa T,Toyooka H,Suto Y

更新日期：1998-12-01 00:00:00

abstract：:Two concentrations of etidocaine (1 and 1.5%) and of pH-adjusted bupivacaine (0.5 and 0.75%, pH 6.8), all fortified with hyaluronidase, were compared as local anesthetics in regional ophthalmic surgery for cataract extraction. The series comprised 160 patients assigned randomly to four groups (n = 40). Each patient re...

journal_title：Anesthesia and analgesia

authors： Sarvela PJ

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Erythropoiesis-stimulating agents, such as erythropoietin (EPO), can be used to treat preoperative anemia. Some studies suggest an increased risk of mortality and thrombotic events, and use in cardiovascular surgery remains off-label. This study compares outcomes in cardiac surgery patients declining blood t...

journal_title：Anesthesia and analgesia

authors： Duce L,Cooter ML,McCartney SL,Lombard FW,Guinn NR

更新日期：2018-08-01 00:00:00

abstract：:The effects of continuous epidural anesthesia and of general anesthesia on the incidence of thromboembolism following total hip replacement were studied. Sixty patients were randomly allotted to one of two groups receiving either epidural or general anesthesia. Epidural anesthesia (N = 30) consisted of 0.5% bupivacain...

journal_title：Anesthesia and analgesia

authors： Modig J,Borg T,Karlström G,Maripuu E,Sahlstedt B

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension and resulting right ventricular (RV) dysfunction are associated with significant perioperative morbidity and mortality. Although echocardiography permits real-time, noninvasive assessment of RV function, objective and comparative measures are underdeveloped, and appropriate animal mode...

journal_title：Anesthesia and analgesia

authors： Bartels K,Brown RD,Fox DL,Bull TM,Neary JM,Dorosz JL,Fonseca BM,Stenmark KR

更新日期：2016-05-01 00:00:00

abstract：:Intraoperative hypoxia occurred in two patients during the maintenance of the medical gas system. Engineers were purging oxygen pipelines with nitrogen to remove particulate debris but were unaware of a connection to operating room pipelines. This case illustrates the importance of communication between anesthesia pro...

journal_title：Anesthesia and analgesia

authors： Elizaga AM,Frerichs RL

更新日期：2000-07-01 00:00:00

abstract：:This study used the activated clotting time (ACT) to determine the clinical onset of four different doses of heparin after bolus injection into the central circulation. Ten consenting adults (Group A) undergoing coronary artery bypass grafting were given 350 U/kg of bovine lung heparin and had simultaneous duplicate a...

journal_title：Anesthesia and analgesia

authors： Heres EK,Speight K,Benckart D,Marquez J,Gravlee GP

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The α2-adrenergic agonist dexmedetomidine is a sedative and can be used as an adjunct to anesthetics. Our primary goal was thus to determine the extent to which dexmedetomidine reduces the requirement for propofol and remifentanil. METHODS:This double-blinded, randomized study (NCT00921284) used an automate...

journal_title：Anesthesia and analgesia

authors： Le Guen M,Liu N,Tounou F,Augé M,Tuil O,Chazot T,Dardelle D,Laloë PA,Bonnet F,Sessler DI,Fischler M

更新日期：2014-05-01 00:00:00

abstract：UNLABELLED:N-methyl-D-aspartate (NMDA) antagonists, such as MK801, delay the development of morphine tolerance. Magnesium, a noncompetitive NMDA antagonist, reduces postoperative morphine requirements. The present study was designed to evaluate the effects of intrathecal co-administration of magnesium sulfate with morp...

journal_title：Anesthesia and analgesia

authors： McCarthy RJ,Kroin JS,Tuman KJ,Penn RD,Ivankovich AD

更新日期：1998-04-01 00:00:00