Barbiturate-benzodiazepine interactions at the gamma-aminobutyric acidA receptor in rat cerebral cortical synaptoneurosomes.

abstract：:As most of us are aware, almost every facet of our society is becoming, for better or worse, progressively more technology-dependent. Technological advancement has made autonomous systems, also known as robots, an integral part of our life in several fields, including medicine. The application of robots in anesthesia ...

journal_title：Anesthesia and analgesia

authors： Zaouter C,Joosten A,Rinehart J,Struys MMRF,Hemmerling TM

更新日期：2020-05-01 00:00:00

abstract：:Local anesthetics have been used clinically for more than a century, but new insights into their mechanisms of action and their interaction with biological systems continue to surprise researchers and clinicians alike. Next to their classic action on voltage-gated sodium channels, local anesthetics interact with calci...

journal_title：Anesthesia and analgesia

authors： Lirk P,Hollmann MW,Strichartz G

更新日期：2018-04-01 00:00:00

abstract：:Waste anesthetic gas scavenging technology has not changed appreciably in the past 30 years. Open reservoir systems entrain high volumes of room air and dilute waste gases before emission into the atmosphere. This process requires a large vacuum pump, which is both costly to install and, although efficient, operates c...

journal_title：Anesthesia and analgesia

authors： Barwise JA,Lancaster LJ,Michaels D,Pope JE,Berry JM

更新日期：2011-11-01 00:00:00

abstract：:The renal effects of pulsatile (pulse pressure 18.0 +/- 1.5 mm Hg [mean +/- SEM]) or nonpulsatile perfusion (mean pulse pressure 1.9 +/- 0.4 mm Hg) during either alpha-stat (mean PaCO2 41.2 +/- 0.9 mm Hg measured at 37 degrees C) or pH-stat (mean PaCO2 60.6 +/- 1.7 mm Hg measured at 37 degrees C) pH management of hypo...

journal_title：Anesthesia and analgesia

authors： Badner NH,Murkin JM,Lok P

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Calmodulin (CaM) activation by Ca(2+), its translocation to the nucleus, and stimulation of phosphorylation of cyclic adenosine monophosphate response element-binding protein (CREB) (P-CREB) are necessary for new gene expression and have been linked to long-term potentiation, a process important in memory fo...

journal_title：Anesthesia and analgesia

authors： Zhang J,Sutachan JJ,Montoya-Gacharna J,Xu CF,Xu F,Neubert TA,Recio-Pinto E,Blanck TJ

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:In 2001, the Center for Medicare and Medicaid Services issued a rule permitting states to "opt-out" of federal regulations requiring physician supervision of nurse anesthetists. We examined the extent to which this rule increased access to anesthesia care for urgent cases. METHODS:Using data from a national...

journal_title：Anesthesia and analgesia

authors： Sun E,Dexter F,Miller TR

更新日期：2016-06-01 00:00:00

abstract：:Enhanced recovery after surgery (ERAS) has rapidly gained popularity in a variety of surgical subspecialities. A large body of literature suggests that ERAS leads to superior outcomes, improved patient satisfaction, reduced length of hospital stay, and cost benefits, without affecting rates of readmission after surger...

journal_title：Anesthesia and analgesia

authors： Soffin EM,Gibbons MM,Ko CY,Kates SL,Wick E,Cannesson M,Scott MJ,Wu CL

更新日期：2019-03-01 00:00:00

abstract：UNLABELLED:Thiopental is a racemate. In this study, we examined whether thiopental total body clearance and its distribution into central nervous system (CNS) tissue of rats was enantioselective. Rats, either anesthetized with halothane or conscious and restrained, were infused to stepwise steady-state targets of 5, 10...

journal_title：Anesthesia and analgesia

authors： Mather LE,Edwards SR,Duke CC,Cousins MJ

更新日期：1999-07-01 00:00:00

abstract：UNLABELLED:The effects of heparinization and the reversal of heparin activity on platelet function after cardiopulmonary bypass have not been well defined. Flow cytometry has become a convenient and powerful technique for characterizing platelets. We examined the expression of a secretion marker (P-selectin) and an agg...

journal_title：Anesthesia and analgesia

authors： Kozek-Langenecker SA,Mohammad SF,Masaki T,Kamerath C,Cheung AK

更新日期：2000-04-01 00:00:00

abstract：:One-hundred and eight-five pairs of gas samples were collected from inspired gas (10 cm behind the head at nose level) and end-tidal gas of persons administering anesthesia in 3 operating rooms during daily routine anesthesia. Mean operating-room N2O concentrations from 22 to 144 ppm (volume/volume [V/V]) were measure...

journal_title：Anesthesia and analgesia

authors： Beynen FM,Knopp TJ,Rehder K

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Insufficient fixation of an epidural catheter may result in migration of the catheter and eventual catheter failure. However, the best fixation method remains to be established. Aron Alpha A (2-ethyl cyanoacrylate) adhesive is approved for clinical use and can be used for surgical adhesion to both skin and b...

journal_title：Anesthesia and analgesia

authors： Tadokoro T,Kakinohana M,Navarro M,Goya M,Odo Y

更新日期：2019-07-01 00:00:00

abstract：:A new mode of pulmonary ventilation called intratracheal pulmonary ventilation (ITPV) was studied. Briefly, a continuous flow of air/oxygen is introduced through a small catheter, the tip of which is positioned at the carina, with a diffuser mounted at its distal end. A timed expiration valve, when closed, provides fo...

journal_title：Anesthesia and analgesia

authors： Kolobow T,Powers T,Mandava S,Aprigliano M,Kawaguchi A,Tsuno K,Mueller E

更新日期：1994-03-01 00:00:00

abstract：:Intraoperative hypoxia occurred in two patients during the maintenance of the medical gas system. Engineers were purging oxygen pipelines with nitrogen to remove particulate debris but were unaware of a connection to operating room pipelines. This case illustrates the importance of communication between anesthesia pro...

journal_title：Anesthesia and analgesia

authors： Elizaga AM,Frerichs RL

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:To prevent reflex-induced bronchoconstriction in patients with asthma, local anesthetics are commonly administered by aerosol or IV as adjunct medication. Lidocaine attenuates responsiveness to a neurally active stimulus that increases tone, but there is scant information about the effect of lidocaine on bas...

journal_title：Anesthesia and analgesia

authors： Chang HY,Togias A,Brown RH

更新日期：2007-05-01 00:00:00

abstract：:As part of an oximetry research effort in which plethysmographic data were collected from moving patients, a wide variety of patient motion affecting pulse oximetry was observed and characterized by the clinical incidence, type, severity and duration of patient motion. 350 patients were observed for movement in clinic...

journal_title：Anesthesia and analgesia

authors： Tobin RM,Pologe JA,Batchelder PB

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a "lighter" depth of sedation. Among these strategies are "analgosedation" protocols, which prioritize pain management and preferentially use IV opioids before administration of continuously...

journal_title：Anesthesia and analgesia

authors： Faust AC,Rajan P,Sheperd LA,Alvarez CA,McCorstin P,Doebele RL

更新日期：2016-10-01 00:00:00

abstract：:In pediatric practice, complications due to the laryngeal mask airway (LMA) have been studied with size 2 LMA, but not with size 1 LMA. We, therefore, compared prospectively the complications induced by LMA size 1 and 2 in 141 children aged 21 days to 11 yr. Intraoperative and lowest SpO2 values after removal of LMA w...

journal_title：Anesthesia and analgesia

authors： Dubreuil M,Laffon M,Plaud B,Penon C,Ecoffey C

更新日期：1993-03-01 00:00:00

abstract：:To investigate the effect of intravenous dopamine on the chemical regulation of ventilation, we studied the ventilatory responses to hypercapnic hypoxia during dopamine infusion. Intravenous dopamine (3 micrograms X kg-1 X min-1) was administered to six healthy human subjects. Two hypoxic challenges (PETO2 = 52.5 +/- ...

journal_title：Anesthesia and analgesia

authors： Sabol SJ,Ward DS

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Impaired cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB) is associated with stroke and other adverse outcomes. Large and small arterial stenosis is prevalent in patients undergoing cardiac surgery. We hypothesize that large and/or small vessel cerebral arterial disease is associa...

journal_title：Anesthesia and analgesia

authors： Nomura Y,Faegle R,Hori D,Al-Qamari A,Nemeth AJ,Gottesman R,Yenokyan G,Brown C,Hogue CW

更新日期：2018-12-01 00:00:00

abstract：:We have developed computer software to store data on all surgical and obstetrical anesthetics administered by our department. The computer system provides information for monitoring the residency training program, department and operating room management, professional fee billing, and research. It imposes little addit...

journal_title：Anesthesia and analgesia

authors： Bashein G,Barna CR

更新日期：1985-04-01 00:00:00

abstract：:The fatal/anesthetic ratio (FAR) in 44 swine weighing 32.6 +/- 0.7 kg (SEM) was determined. Fatal anesthetic concentration (the numerator for FAR) was defined as the end-tidal concentration at which the pig lived at least 10 min, during experiments that involved step increments in anesthetic concentrations. Previously...

journal_title：Anesthesia and analgesia

authors： Roberts SL,Gilbert M,Tinker JH

更新日期：1987-06-01 00:00:00

abstract：:Hypertonic saline improves organ perfusion and animal survival during hemorrhagic shock because it expands plasma volume and increases tissue oxygenation. Because both decreased and increased myocardial performance have been reported with hypertonic saline, the effects of hyperosmolarity and the mechanism accounting f...

journal_title：Anesthesia and analgesia

authors： Mouren S,Delayance S,Mion G,Souktani R,Fellahi JL,Arthaud M,Baron JF,Viars P

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Incomplete reversal with a recommended 5-g dose of idarucizumab has been reported in patients with excessively high dabigatran concentrations. A timely detection of reversal failure after idarucizumab using whole blood (WB) coagulation testing is clinically useful. The aims of this study were to determine re...

journal_title：Anesthesia and analgesia

authors： Takeshita S,Tanaka KA,Sawa T,Sanda M,Mizobe T,Ogawa S

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Cerebral cholinergic transmission plays a key role in cognitive function, and anticholinergic drugs administered during the perioperative phase are a hypothetical cause of postoperative cognitive dysfunction (POCD). We hypothesized that a perioperative increase in serum anticholinergic activity (SAA) is asso...

journal_title：Anesthesia and analgesia

authors： Rossi A,Burkhart C,Dell-Kuster S,Pollock BG,Strebel SP,Monsch AU,Kern C,Steiner LA

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Sepsis is currently the leading cause of direct maternal death in the United Kingdom. In this study, we aimed to determine frequency, temporal trends, and independent associations for severe sepsis during hospitalization for delivery in the United States. METHODS:Data were obtained from the Nationwide Inpat...

journal_title：Anesthesia and analgesia

authors： Bauer ME,Bateman BT,Bauer ST,Shanks AM,Mhyre JM

更新日期：2013-10-01 00:00:00

abstract：UNLABELLED:Combined spinal-epidural anesthesia (CSE) is a popular technique for cesarean delivery. Regional blocks in obstetrics are often performed with the parturient in the sitting position because the midline may be recognized more easily than in the lateral decubitus position. When conventional spinal anesthesia i...

journal_title：Anesthesia and analgesia

authors： Yun EM,Marx GF,Santos AC

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:The possibility that μ opioid agonists can influence cancer recurrence is a subject of recent interest. Epidemiologic studies suggested that there were differences in cancer recurrence in breast and prostate cancer contingent on anesthetic regimens. In this study, we identify a possible mechanism for these e...

journal_title：Anesthesia and analgesia

authors： Mathew B,Lennon FE,Siegler J,Mirzapoiazova T,Mambetsariev N,Sammani S,Gerhold LM,LaRiviere PJ,Chen CT,Garcia JG,Salgia R,Moss J,Singleton PA

更新日期：2011-03-01 00:00:00

abstract：:The correlation between the potency of inhaled anesthetics and their solubility in a hydrophobic phase provides an opportunity to define better the characteristics of the anesthetic site of action. The correlation implies that inhaled anesthetics act in a hydrophobic site and that the solvent used has properties repre...

journal_title：Anesthesia and analgesia

authors： Taheri S,Halsey MJ,Liu J,Eger EI 2nd,Koblin DD,Laster MJ

更新日期：1991-05-01 00:00:00

abstract：:Aging and disease may make the elderly patient with cardiac disease particularly susceptible to hypotension during spinal anesthesia. We studied 15 men, 59-80 y old, with histories of prior myocardial infarction (n = 9), congestive heart failure (n = 2), and/or stable myocardial ischemia (n = 11) given spinal anesthes...

journal_title：Anesthesia and analgesia

authors： Rooke GA,Freund PR,Jacobson AF

更新日期：1997-07-01 00:00:00

abstract：UNLABELLED:Propofol is a cardiac depressant with minimal diastolic effects in the adult myocardium. Cardiac effects of propofol in the newborn are unknown. We examined hemodynamic variables and systolic and diastolic left ventricular function in 12 newborn pigs exposed to propofol at three different infusion rates (7.5...

journal_title：Anesthesia and analgesia

authors： Graham MR,Thiessen DB,Mutch WA

更新日期：1998-04-01 00:00:00