Sciatic cryoneurolysis in rats: a model of sympathetically independent pain. Part 1: Effects of sympathectomy.

Abstract:

:The purpose of this study was to evaluate the effects of preemptive and postlesion sympathectomy in the sciatic cryoneurolysis (SCN) model of neuropathic pain in rats. SCN in rats produces a prolonged significant mechanical allodynia (hypersensitivity to previously non-noxious mechanical stimuli) with no thermal hyperalgesia. In at least two other models, sympathectomy is effective in attenuating existing mechanical allodynia and thermal hyperalgesia or deterring their development after nerve injury. These models appear to mimic the direct sympathetic involvement characteristic of the clinical syndrome termed sympathetically maintained pain (SMP). To investigate these concepts in the SCN model, sympathectomy was performed prior to SCN in animals with established SCN-induced allodynia. Sympathectomy did not alter the pattern of existing allodynia or its development in this model. The results suggest that SCN is a useful and easily reproducible model of sympathetically independent pain (SIP).

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Willenbring S,Beauprie IG,DeLeo JA

doi

10.1097/00000539-199509000-00021

subject

Has Abstract

pub_date

1995-09-01 00:00:00

pages

544-8

issue

3

eissn

0003-2999

issn

1526-7598

journal_volume

81

pub_type

杂志文章
  • Halogenation and anesthetic potency.

    abstract::Previous studies have shown that the anesthetic potency of organic compounds increases as a given halogen is replaced with successively larger halogens. These studies often are limited in the accuracy of determination of potency, rarely correlate potency with physical properties, and usually fail to include ether comp...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Targ AG,Yasuda N,Eger EI 2nd,Huang G,Vernice GG,Terrell RC,Koblin DD

    更新日期:1989-05-01 00:00:00

  • Clinical and metabolic responses to different types of premedication.

    abstract::Clinical and metabolic responses to three types of premedication were studied in ASA physical status I patients given any one of the following: (a) 0.5 mg of atropine and 50 mg of meperidine given intramuscularly plus an oral placebo tablet (n = 14), (b) 10 mg of oral diazepam and an intramuscular placebo (2 mL NaCl, ...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Kirvelä OA,Kanto JH

    更新日期:1991-07-01 00:00:00

  • Electro-acupuncture at the Zusanli, Yanglingquan, and Kunlun points does not reduce anesthetic requirement.

    abstract:UNLABELLED:We tested the hypothesis that electro-acupuncture at the Zusanli, Yanglingquan, and Kunlun acupuncture points on the legs decreases anesthetic requirement. Fourteen young, healthy volunteers were anesthetized with desflurane on two separate days. Needle electrodes were positioned at the three acupuncture poi...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000539-200207000-00017

    authors: Morioka N,Akça O,Doufas AG,Chernyak G,Sessler DI

    更新日期:2002-07-01 00:00:00

  • The minimum alveolar anesthetic concentration of 2-, 3-, and 4-alcohols and ketones in rats: relevance to anesthetic mechanisms.

    abstract::The Meyer-Overton hypothesis predicts that anesthetic potency correlates inversely with lipophilicity; e.g., MAC times the olive oil/gas partition coefficient equals a constant of approximately 1.82 +/- 0.56 atm (mean +/- sd) for conventional inhaled anesthetics. MAC is the minimum alveolar concentration of anesthetic...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000204258.00676.98

    authors: Won A,Oh I,Liao M,Sonner JM,Harris RA,Laster MJ,Brosnan R,Trudell JR,Eger EI 2nd

    更新日期:2006-05-01 00:00:00

  • Evaluating Patient-Centered Outcomes in Clinical Trials of Procedural Sedation, Part 1 Efficacy: Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations.

    abstract::The Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research, established by the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks public-private partnership with the US Food and Drug Administration, convened a meeting of sedation e...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000001566

    authors: Williams MR,Ward DS,Carlson D,Cravero J,Dexter F,Lightdale JR,Mason KP,Miner J,Vargo JJ,Berkenbosch JW,Clark RM,Constant I,Dionne R,Dworkin RH,Gozal D,Grayzel D,Irwin MG,Lerman J,O'Connor RE,Pandharipande P,Rappap

    更新日期:2017-03-01 00:00:00

  • The effect of fibrinogen substitution on reversal of dilutional coagulopathy: an in vitro model.

    abstract::Colloids and crystalloids are usually administered as treatment for hypovolemia in severely injured patients. However, dilution of clotting factors and platelets together with impaired fibrinogen polymerization are associated with fluid therapy and may aggravate hemorrhage, thus worsening final outcome of these patien...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000194359.06286.d4

    authors: Fries D,Innerhofer P,Reif C,Streif W,Klingler A,Schobersberger W,Velik-Salchner C,Friesenecker B

    更新日期:2006-02-01 00:00:00

  • Hemodynamic effects of desflurane/nitrous oxide anesthesia in volunteers.

    abstract::We determined the cardiovascular effects of 0.91, 1.34, and 1.74 MAC of desflurane/nitrous oxide anesthesia (60% inspired nitrous oxide contributed 0.5 MAC at each level) in 12 healthy, normocapnic male volunteers. Desflurane/nitrous oxide anesthesia decreased systemic blood pressures, cardiac index, stroke volume ind...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-199108000-00008

    authors: Cahalan MK,Weiskopf RB,Eger EI 2nd,Yasuda N,Ionescu P,Rampil IJ,Lockhart SH,Freire B,Peterson NA

    更新日期:1991-08-01 00:00:00

  • Nocebo-induced hyperalgesia during local anesthetic injection.

    abstract::Common practice during local anesthetic injection is to warn the patient using words such as: "You will feel a big bee sting; this is the worst part." Our hypothesis was that using gentler words for administration of the local anesthetic improves pain perception and patient comfort. One hundred forty healthy women at ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0b013e3181cc5727

    authors: Varelmann D,Pancaro C,Cappiello EC,Camann WR

    更新日期:2010-03-01 00:00:00

  • Joint hypothesis testing and gatekeeping procedures for studies with multiple endpoints.

    abstract::A claim of superiority of one intervention over another often depends naturally on results from several outcomes of interest. For such studies the common practice of making conclusions about individual outcomes in isolation can be problematic. For example, an intervention might be shown to improve one outcome (e.g., p...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3182504435

    authors: Mascha EJ,Turan A

    更新日期:2012-06-01 00:00:00

  • Is succinylcholine after pretreatment with d-tubocurarine and lidocaine contraindicated for outpatient anesthesia?

    abstract:UNLABELLED:Because succinylcholine has obvious advantages for facilitating endotracheal intubation in the ambulatory setting (e.g., low cost, fast onset, and no need for reversal of neuromuscular block), it is important to determine whether this muscle relaxant is indeed associated with an increased incidence of postop...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200008000-00015

    authors: Mikat-Stevens M,Sukhani R,Pappas AL,Fluder E,Kleinman B,Stevens RA

    更新日期:2000-08-01 00:00:00

  • Gallamine administered by combined bolus and infusion.

    abstract::A technique combining an intravenous bolus and intravenous infusion regimen of gallamine based on its pharmacokinetics was developed to produce continuous relaxation during surgery. The combination of a bolus dose of gallamine, 2.5 mg/kg, and infusion, 0.8 mg/kg/hr, was tested in 11 patients. In 10 patients, surgery c...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Shanks CA,Funk DI,Avram MJ,Henthorn TK

    更新日期:1982-10-01 00:00:00

  • Intrabiliary pressure changes produced by narcotic drugs and inhalation anesthetics in guinea pigs.

    abstract::The effects of narcotic agents and two inhalation anesthetics on intrabiliary pressure (IBP) were measured before and after morphine (0.2 mg/kg), meperidine (2 mg/kg), fentanyl (0.002 mg/kg), or pentazocine (1 mg/kg) given intramuscularly to guinea pigs, and after halothane (0.5, 1.0, 1.5, or 2.0 MAC) or enflurane (sa...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Arguelles JE,Franatovic Y,Romo-Salas F,Aldrete JA

    更新日期:1979-03-01 00:00:00

  • Effects of augmenting cardiac contractility, preload, and heart rate on cardiac output during enflurane anesthesia.

    abstract::Changes in cardiac output in response to augmenting cardiac contractility, preload, and heart rate during enflurane anesthesia were examined in 12 open-chested dogs. Cardiac contractility was assessed by the slope of the end-systolic pressure-volume relation (Emax). Dobutamine (3, 6, and 9 micrograms.kg-1.min-1) was a...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-199111000-00014

    authors: Sato M,Hoka S,Arimura H,Ono K,Yoshitake J

    更新日期:1991-11-01 00:00:00

  • The effects of plasma and brain magnesium concentrations on lidocaine-induced seizures in the rat.

    abstract::Lidocaine and MgSO4 are often coadministered to patients with pregnancy-induced hypertension. This study examined whether MgSO4 alters the lidocaine-seizure threshold in the rat and, if so, whether systemic MgSO4 administration is as effective as intracerebroventricular MgSO4 infusion. In Experiment 1, rats were admin...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199612000-00016

    authors: Kim YJ,McFarlane C,Warner DS,Baker MT,Choi WW,Dexter F

    更新日期:1996-12-01 00:00:00

  • The bispectral index and explicit recall during the intraoperative wake-up test for scoliosis surgery.

    abstract:UNLABELLED:In this prospective study, we evaluated the bispectral index (BIS) and postoperative recall during the intraoperative wake-up examination in 34 children and adolescents undergoing scoliosis surgery. Each anesthesiologist was blinded to BIS values throughout surgery and the wake-up test. The BIS, mean arteria...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200206000-00018

    authors: McCann ME,Brustowicz RM,Bacsik J,Sullivan L,Auble SG,Laussen PC

    更新日期:2002-06-01 00:00:00

  • Morphine kinetics and kidney transplantation: morphine removal is influenced by renal ischemia.

    abstract::Morphine plasma concentrations were determined in six patients receiving kidney transplants from living-related donors, and nine patients receiving kidney transplants from cadavers. The total cold ischemic time was about 2 hr for kidneys from living-related donors and 14 hr for those from cadavers. After an intravenou...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Sear J,Moore A,Hunniset A,Baldwin D,Allen M,Hand C,McQuay H,Morris P

    更新日期:1985-11-01 00:00:00

  • The anesthetic considerations in patients with ventricular assist devices presenting for noncardiac surgery: a review of eight cases.

    abstract:IMPLICATIONS:The number of patients supported by ventricular assist devices (VADs) that present for noncardiac surgery is increasing in our institution. Our recent experience with eight such patients is reported, along with a review of the most commonly implanted VADs and the anesthetic implications and considerations ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200207000-00007

    authors: Stone ME,Soong W,Krol M,Reich DL

    更新日期:2002-07-01 00:00:00

  • Effects of enflurane on contractile response of canine trachealis muscle.

    abstract::The effect of enflurane anesthesia on bronchomotor tone was studied in 15 dogs, using isolated tracheal segments in situ. In six animals, the changes of tracheal tension in response to changing enflurane concentration were continuously measured while keeping tidal volume, respiratory frequency, and end-tidal PCO2 cons...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Kochi T,Hagiya M,Mizuguchi T

    更新日期:1989-07-01 00:00:00

  • Bupivacaine and other amide local anesthetics inhibit the hydrolysis of chloroprocaine by human serum.

    abstract::The rate of hydrolysis of chloroprocaine by human serum was studied in the presence and absence of a number of aminde local anesthetics and their metabolites. Bupivacaine (2.4 microgram/ml) and etidocaine (2.3 microgram/ml) caused 38% and 21% inhibition respectively of the rate of chloroprocaine hydrolysis. Circulatin...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/00000539-197809000-00004

    authors: Lalka D,Vicuna N,Burrow SR,Jones DJ,Ludden TM,Haegele KD,McNay JL

    更新日期:1978-09-01 00:00:00

  • The effect of amitriptyline, gabapentin, and carbamazepine on morphine-induced hypercarbia in rabbits.

    abstract:BACKGROUND:Severe exacerbation of chronic neuropathic pain often requires morphine in patients already treated with drugs such as tricyclic antidepressants, carbamazepine and gabapentin. However, it is unclear if a combination of these drugs intensifies the effects of morphine on the respiratory system and, if so, whet...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e31817e6e53

    authors: Kozer E,Levichek Z,Hoshino N,Kapur B,Leombruno J,Taguchi N,Garcia-Bournissen F,Koren G,Ito S

    更新日期:2008-10-01 00:00:00

  • Dietary omega-3 fatty acids may be associated with increased neuropathic pain in nerve-injured rats.

    abstract:UNLABELLED:Certain dietary proteins and oils are capable of decreasing chronic neuropathic pain levels in rats after partial sciatic nerve ligation injury. We tested, for the first time, the role of dietary polyunsaturated fatty acids in suppressing pain in partial sciatic nerve ligation-injured rats. Six groups of mal...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ANE.0000158469.11775.52

    authors: Pérez J,Ware MA,Chevalier S,Gougeon R,Shir Y

    更新日期:2005-08-01 00:00:00

  • Cerebral near-infrared spectroscopy monitoring and neurologic outcomes in adult cardiac surgery patients: a systematic review.

    abstract:BACKGROUND:Near-infrared spectroscopy is used during cardiac surgery to monitor the adequacy of cerebral perfusion. In this systematic review, we evaluated available data for adult patients to determine (1) whether decrements in cerebral oximetry during cardiac surgery are associated with stroke, postoperative cognitiv...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,评审

    doi:10.1213/ANE.0b013e318277a255

    authors: Zheng F,Sheinberg R,Yee MS,Ono M,Zheng Y,Hogue CW

    更新日期:2013-03-01 00:00:00

  • Hemodynamic effects of portal triad clamping with and without pneumoperitoneum: an echocardiographic study.

    abstract::The decrease of cardiac index observed during portal triad clamping (PTC) with and without pneumoperitoneum has been studied only with right heart catheterization. To better understand this decrease of cardiac index, we investigated the balance between the adequacy of preload and the ability of the heart to pump again...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ANE.0000144592.20499.12

    authors: Decailliot F,Streich B,Heurtematte Y,Duvaldestin P,Cherqui D,Stéphan F

    更新日期:2005-03-01 00:00:00

  • Preincisional intravenous pentoxifylline attenuating perioperative cytokine response, reducing morphine consumption, and improving recovery of bowel function in patients undergoing colorectal cancer surgery.

    abstract::Cytokine release during surgery can produce a long-lasting hyperalgesia. Thus, preoperatively-administered cytokine inhibitors might reduce the production of cytokines, decreasing central nervous system sensitization and improving the quality of postoperative pain relief. We investigated the hypothesis that preincisio...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/01.ANE.0000132974.32249.C8

    authors: Lu CH,Chao PC,Borel CO,Yang CP,Yeh CC,Wong CS,Wu CT

    更新日期:2004-11-01 00:00:00

  • The efficacy of the "BURP" maneuver during a difficult laryngoscopy.

    abstract::The displacement of the larynx in the three specific directions (a) posteriorly against the cervical vertebrae, (b) superiorly as possible, and (c) slightly laterally to the right have been reported and named the "BURP" maneuver. We evaluated the efficacy of the BURP maneuver in improving visualization of the larynx. ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-199702000-00033

    authors: Takahata O,Kubota M,Mamiya K,Akama Y,Nozaka T,Matsumoto H,Ogawa H

    更新日期:1997-02-01 00:00:00

  • Distal tourniquet or leg position after injection enhances the efficacy of sciatic nerve blockade by the popliteal approach.

    abstract:BACKGROUND:In this study, we hypothesized that leg positioning and distal tourniquet application, when compared with neutral positioning of the leg, alters the efficacy of sciatic nerve block performed by the double-stimulation technique. METHODS:Ninety randomized, consecutive, ASA physical status I to III patients un...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0b013e31822f8b99

    authors: Sertoz N,Deniz MN,Ayanoglu HO

    更新日期:2011-12-01 00:00:00

  • Ropivacaine continuous wound infusion versus epidural morphine for postoperative analgesia after cesarean delivery: a randomized controlled trial.

    abstract:BACKGROUND:The infusion of local anesthetic in the surgical wound is helpful in the multimodal management of postoperative pain. We hypothesized that local anesthetic wound infusion after cesarean delivery would provide better pain control than epidural morphine analgesia. METHODS:Healthy, term women scheduled for ele...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0b013e3182368e87

    authors: O'Neill P,Duarte F,Ribeiro I,Centeno MJ,Moreira J

    更新日期:2012-01-01 00:00:00

  • Protocolized intensive care unit management of analgesia, sedation, and delirium improves analgesia and subsyndromal delirium rates.

    abstract:BACKGROUND:Sedatives and analgesics, in doses that alter consciousness in the intensive care unit (ICU), contribute to delirium and mortality. Pain, agitation, and delirium can be monitored in ICU patients. These symptoms were noted before (PRE) and after (POST) a protocol to alleviate undesirable symptoms. Analgesia a...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3181d7e1b8

    authors: Skrobik Y,Ahern S,Leblanc M,Marquis F,Awissi DK,Kavanagh BP

    更新日期:2010-08-01 00:00:00

  • The Impact of Surgery and Stored Red Blood Cell Transfusions on Nitric Oxide Homeostasis.

    abstract:BACKGROUND:Cell-free hemoglobin (Hb) forms in stored red blood cells (RBCs) as a result of hemolysis. Studies suggest that this cell-free Hb may decrease nitric oxide (NO) bioavailability, potentially leading to endothelial dysfunction, vascular injury, and multiorgan dysfunction after transfusion. We tested the hypoth...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000001392

    authors: Nagababu E,Scott AV,Johnson DJ,Goyal A,Lipsitz JA,Barodka VM,Berkowitz DE,Frank SM

    更新日期:2016-08-01 00:00:00

  • Recent advances in and limitations of cardiac output monitoring by means of electrical impedance tomography.

    abstract:BACKGROUND:Currently, the monitoring of cardiac output (CO) and stroke volume (SV) is mainly performed using invasive techniques. Therefore, performing CO monitoring noninvasively by means of electrical impedance tomography (EIT) would be advantageous for intensive care. Our hypothesis was that, by means of EIT, it is ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000000241

    authors: Pikkemaat R,Lundin S,Stenqvist O,Hilgers RD,Leonhardt S

    更新日期:2014-07-01 00:00:00